The Ph.D. Program for Neural Regenerative Medicine

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output

2020

AR ubiquitination induced by the curcumin analog suppresses growth of temozolomide-resistant glioblastoma through disrupting GPX4-Mediated redox homeostasis

Chen, T. C., Chuang, J. Y., Ko, C. Y., Kao, T. J., Yang, P. Y., Yu, C. H., Liu, M. S., Hu, S. L., Tsai, Y. T., Chan, H., Chang, W. C. & Hsu, T. I., Feb 1 2020, In : Redox Biology. 30, p. 101413 101413.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Early transcranial direct current stimulation treatment exerts neuroprotective effects on 6-OHDA-induced Parkinsonism in rats

Feng, X. J., Huang, Y. T., Huang, Y. Z., Kuo, C. W., Peng, C. W., Rotenberg, A., Juan, C. H., Pei, Y. C., Chen, Y. H., Chen, K. Y., Chiang, Y. H., Liu, H. H., Wu, J. X. & Hsieh, T. H., May 1 2020, In : Brain Stimulation. 13, 3, p. 655-663 9 p.

Research output: Contribution to journalArticle

Open Access

Efficient labeling of mesenchymal stem cells for high sensitivity long-term MRI monitoring in live mice brains

Ahmed Ali, A. A., Shahror, R. A. & Chen, K. Y., Jan 1 2020, In : International Journal of Nanomedicine. 15, p. 97-114 18 p.

Research output: Contribution to journalArticle

Open Access

Transplantation of mesenchymal stem cells overexpressing fibroblast growth factor 21 facilitates cognitive recovery and enhances neurogenesis in a mouse model of traumatic brain injury

Shahror, R. A., Linares, G. R., Wang, Y., Hsueh, S. C., Wu, C. C., Chuang, D. M., Chiang, Y. H. & Chen, K. Y., Jan 1 2020, In : Journal of Neurotrauma. 37, 1, p. 14-26 13 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019

(−)-Phenserine tartrate (PhenT) as a treatment for traumatic brain injury

Greig, N. H., Lecca, D., Hsueh, S. C., Nogueras-Ortiz, C., Kapogiannis, D., Tweedie, D., Glotfelty, E. J., Becker, R. E., Chiang, Y. H. & Hoffer, B. J., Jan 1 2019, (Accepted/In press) In : CNS Neuroscience and Therapeutics.

Research output: Contribution to journalArticle

Open Access

Altered frontal aslant tracts as a heritable neural basis of social communication deficits in autism spectrum disorder: A sibling study using tract-based automatic analysis

Lo, Y. C., Chen, Y. J., Hsu, Y. C., Chien, Y. L., Gau, S. S. F. & Tseng, W. Y. I., Feb 1 2019, In : Autism Research. 12, 2, p. 225-238 14 p.

Research output: Contribution to journalArticle

Open Access

Aspirin better than clopidogrel on major adverse cardiovascular events reduction after ischemic stroke: A retrospective nationwide cohort study

Vidyanti, A. N., Chan, L., Lin, C. L., Muo, C. H., Hsu, C. Y., Chen, Y. C., Wu, D. & Hu, C. J., Jan 1 2019, In : PLoS ONE. 14, 8, e0221750.

Research output: Contribution to journalArticle

Open Access
Open Access

BPR1M97, a dual mu opioid receptor/nociceptin-orphanin FQ peptide receptor agonist, produces potent antinociceptive effects with safer properties than morphine

Chao, P. K., Chang, H. F., Chang, W. T., Yeh, T. K., Ou, L. C., Chuang, J. Y., Tsu-An Hsu, J., Tao, P. L., Loh, H. H., Shih, C., Ueng, S. H. & Yeh, S. H., Jan 1 2019, In : Neuropharmacology. 107678.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Cerebro-Cerebellar Pathways for Verbal Working Memory

Sobczak-Edmans, M., Lo, Y-C., Hsu, Y-C., Chen, Y-J., Kwok, F. Y., Chuang, K-H., Tseng, W-Y. I. & Chen, S. H. A., Jan 8 2019, In : Frontiers in Human Neuroscience. 12, p. 530

Research output: Contribution to journalArticle

Convallatoxin enhance the ligand-induced mu-opioid receptor endocytosis and attenuate morphine antinociceptive tolerance in mice

Chao, P. K., Chang, H. F., Ou, L. C., Chuang, J. Y., Lee, P. T., Chang, W. T., Chen, S. C., Ueng, S. H., Hsu, J. T. A., Tao, P. L., Law, P. Y., Loh, H. H. & Yeh, S. H., Dec 1 2019, In : Scientific Reports. 9, 1, 2405.

Research output: Contribution to journalArticle

1 Citation (Scopus)

CYP17A1 maintains the survival of glioblastomas by regulating SAR1-mediated endoplasmic reticulum health and redox homeostasis

Lin, H. Y., Ko, C. Y., Kao, T. J., Yang, W. B., Tsai, Y. T., Chuang, J. Y., Hu, S. L., Yang, P. Y., Lo, W. L. & Hsu, T. I., Sep 2019, In : Cancers. 11, 9, 1378.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
3 Citations (Scopus)

Designing and implementing a novel transcranial electrostimulation system for neuroplastic applications: A preliminary study

Li, Y. T., Chen, S. C., Yang, L. Y., Hsieh, T. H. & Peng, C. W., May 1 2019, In : IEEE Transactions on Neural Systems and Rehabilitation Engineering. 27, 5, p. 805-813 9 p., 8680031.

Research output: Contribution to journalArticle

Early sensory neurophysiological changes in prediabetes

Lin, Y. C., Lin, C. S. Y., Chang, T. S., Lee, J. E., Tani, J., Chen, H. J. & Sung, J. Y., Jan 1 2019, (Accepted/In press) In : Journal of Diabetes Investigation.

Research output: Contribution to journalArticle

Open Access

Editorial: Risk factors and outcome predicating biomarker of neurodegenerative diseases

Hu, C. J. & Octave, J. N., Jan 1 2019, In : Frontiers in Neurology. 10, February, 45.

Research output: Contribution to journalReview article

Open Access
Open Access
3 Citations (Scopus)

Enrichment of superoxide dismutase 2 in glioblastoma confers to acquisition of temozolomide resistance that is associated with tumor-initiating cell subsets

Chien, C. H., Chuang, J. Y., Yang, S. T., Yang, W. B., Chen, P. Y., Hsu, T. I., Huang, C. Y., Lo, W. L., Yang, K. Y., Liu, M. S., Chu, J. M., Chung, P. H., Liu, J. J., Chou, S. W., Chen, S. H. & Chang, K. Y., Oct 19 2019, In : Journal of Biomedical Science. 26, 1, 77.

Research output: Contribution to journalArticle

Open Access

Erratum: A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy (Oncotarget (2015) 6 (13671–13687) DOI: 10.18632/oncotarget.3701)

Hsu, T. I., Chen, Y. J., Hung, C. Y., Wang, Y. C., Lin, S. J., Su, W. C., Lai, M. D., Kim, S. Y., Wang, Q., Qian, K., Goto, M., Zhao, Y., Kashiwada, Y., Lee, K. H., Chang, W. C. & Hung, J. J., Jan 1 2019, In : Oncotarget. 10, 60, p. 6536-6537 2 p.

Research output: Contribution to journalComment/debate

Gene-Embedded Nanostructural Biotic-Abiotic Optoelectrode Arrays Applied for Synchronous Brain Optogenetics and Neural Signal Recording

Huang, W. C., Chi, H. S., Lee, Y. C., Lo, Y. C., Liu, T. C., Chiang, M. Y., Chen, H. Y., Li, S. J., Chen, Y. Y. & Chen, S. Y., Mar 27 2019, In : ACS Applied Materials and Interfaces. 11, 12, p. 11270-11282 13 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
Open Access

Ketamine ameliorates severe traumatic event-induced antidepressant-resistant depression in a rat model through ERK activation

Lee, C. W., Chen, Y. J., Wu, H. F., Chung, Y. J., Lee, Y. C., Li, C. T. & Lin, H. C., Jul 13 2019, In : Progress in Neuro-Psychopharmacology and Biological Psychiatry. 93, p. 102-113 12 p.

Research output: Contribution to journalArticle

Leukemia Inhibitory Factor Promotes Castration-resistant Prostate Cancer and Neuroendocrine Differentiation by Activated ZBTB46

Liu, Y-N., Niu, S., Chen, W-Y., Zhang, Q., Tao, Y., Chen, W-H., Jiang, K-C., Chen, X., Shi, H., Liu, A., Li, J., Li, Y., Lee, Y-C., Zhang, X. & Huang, J., Apr 8 2019, In : Clinical cancer research : an official journal of the American Association for Cancer Research.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Long-term voluntary physical exercise exerts neuroprotective effects and motor disturbance alleviation in a rat model of Parkinson's disease

Tsai, W. L., Chen, H. Y., Huang, Y. Z., Chen, Y. H., Kuo, C. W., Chen, K. Y. & Hsieh, T. H., Jan 1 2019, In : Behavioural Neurology. 2019, 4829572.

Research output: Contribution to journalArticle

Open Access

Modulation of Theta-Band Local Field Potential Oscillations Across Brain Networks With Central Thalamic Deep Brain Stimulation to Enhance Spatial Working Memory

Chang, C. W., Lo, Y. C., Lin, S. H., Yang, S. H., Lin, H. C., Lin, T. C., Li, S. J., Hsieh, C. C. J., Ro, V., Chung, Y. J., Chang, Y. C., Lee, C. W., Kuo, C. H., Chen, S. Y. & Chen, Y. Y., Nov 26 2019, In : Frontiers in Neuroscience. 13, 1269.

Research output: Contribution to journalArticle

Open Access

Morphological control of mitochondria as the novel mechanism of Gastrodia elata in attenuating mutant huntingtin-induced protein aggregations

Huang, N. K., Lin, C. C., Lin, Y. L., Huang, C. L., Chiou, C. T., Lee, Y. C., Lee, S. Y., Huang, H. T. & Yang, Y. C., Jun 1 2019, In : Phytomedicine. 59, 152756.

Research output: Contribution to journalArticle

2 Citations (Scopus)

MR imaging central thalamic deep brain stimulation restored autistic-like social deficits in the rat

Lin, T. C., Lo, Y. C., Lin, H. C., Li, S. J., Lin, S. H., Wu, H. F., Chu, M. C., Lee, C. W., Lin, I. C., Chang, C. W., Liu, Y. C., Chen, T. C., Lin, Y. J., Ian Shih, Y. Y. & Chen, Y. Y., Nov 1 2019, In : Brain Stimulation. 12, 6, p. 1410-1420 11 p.

Research output: Contribution to journalArticle

Neuromodulatory Effects of Transcranial Direct Current Stimulation on Motor Excitability in Rats

Liu, H. H., He, X. K., Chen, H. Y., Peng, C. W., Rotenberg, A., Juan, C. H., Pei, Y. C., Liu, H. L., Chiang, Y. H., Wang, J. Y., Feng, X. J., Huang, Y. Z. & Hsieh, T. H., Jan 1 2019, In : Neural Plasticity. 2019, 4252943.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

NPGPx-Mediated Adaptation to Oxidative Stress Protects Motor Neurons from Degeneration in Aging by Directly Modulating O-GlcNAcase

Hsieh, Y. L., Su, F. Y., Tsai, L. K., Huang, C. C., Ko, Y. L., Su, L. W., Chen, K. Y., Shih, H. M., Hu, C. M. & Lee, W. H., Nov 19 2019, In : Cell Reports. 29, 8, p. 2134-2143.e7

Research output: Contribution to journalArticle

Open Access

Plasmon-Activated Water Reduces Amyloid Burden and Improves Memory in Animals with Alzheimer’s Disease

Cheng, C. H., Lin, K. J., Hong, C. T., Wu, D., Chang, H. M., Liu, C. H., Hsiao, I. T., Yang, C. P., Liu, Y. C. & Hu, C. J., Dec 1 2019, In : Scientific Reports. 9, 1, 13252.

Research output: Contribution to journalArticle

Open Access

Pomalidomide Reduces Ischemic Brain Injury in Rodents

Tsai, Y. R., Tweedie, D., Navas-Enamorado, I., Scerba, M. T., Chang, C. F., Lai, J. H., Wu, J. C. C., Chen, Y. H., Kang, S. J., Hoffer, B. J., de Cabo, R., Greig, N. H., Chiang, Y. H. & Chen, K. Y., Apr 1 2019, In : Cell Transplantation. 28, 4, p. 439-450 12 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Potential therapeutic effect of curcumin, a natural mTOR inhibitor, in tuberous sclerosis complex

Kuo, C. J., Huang, C. C., Chou, S. Y., Lo, Y. C., Kao, T. J., Huang, N. K., Lin, C., Lin, H. C., Lin, H. C. & Lee, Y. C., Feb 15 2019, In : Phytomedicine. 54, p. 132-139 8 p.

Research output: Contribution to journalArticle

Prevalence and clinical characteristics of stroke patients with p.R544C NOTCH3 mutation in Taiwan

Tang, S. C., Chen, Y. R., Chi, N. F., Chen, C. H., Cheng, Y. W., Hsieh, F. I., Hsieh, Y. C., Yeh, H. L., Sung, P. S., Hu, C. J., Chern, C. M., Lin, H. J., Lien, L. M., Peng, G. S., Chiou, H. Y. & Jeng, J. S., Jan 1 2019, In : Annals of Clinical and Translational Neurology. 6, 1, p. 121-128 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons

Lin, H. C., Ching, Y. H., Huang, C. C., Pao, P. C., Lee, Y. H., Chang, W. C., Kao, T. J. & Lee, Y. C., Apr 26 2019, In : Journal of Biomedical Science. 26, 1, 30.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Sp1 in Astrocyte Is Important for Neurite Outgrowth and Synaptogenesis

Hung, C. Y., Hsu, T. I., Chuang, J. Y., Su, T. P., Chang, W. C. & Hung, J. J., Jan 1 2019, In : Molecular Neurobiology.

Research output: Contribution to journalArticle

Open Access

The rs1256328 (ALPL) and rs12654812 (RGS14) Polymorphisms are Associated with Susceptibility to Calcium Nephrolithiasis in a Taiwanese population

Chen, W. C., Chou, W. H., Chu, H. W., Huang, C. C., Liu, X., Chang, W. P., Chou, Y. H. & Chang, W. C., Dec 1 2019, In : Scientific Reports. 9, 1, 17296.

Research output: Contribution to journalArticle

Open Access
Open Access

Transcriptomopathies of pre- and post-symptomatic frontotemporal dementia-like mice with TDP-43 depletion in forebrain neurons

Wu, L. S., Cheng, W. C., Chen, C. Y., Wu, M. C., Wang, Y. C., Tseng, Y. H., Chuang, T. J. & Shen, C. K. J., Mar 29 2019, In : Acta neuropathologica communications. 7, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Unsupervised Classification of Cerebrospinal Fluid by Statistical Indicators

Lee, K. R., Yeh, Y. X., Wu, C. C., Lin, J. & Chiang, Y. H., Jan 16 2019, Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018. Institute of Electrical and Electronics Engineers Inc., p. 3827-3832 6 p. 8616645. (Proceedings - 2018 IEEE International Conference on Systems, Man, and Cybernetics, SMC 2018).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Voluntary exercise delays progressive deterioration of markers of metabolism and behavior in a mouse model of Parkinson's disease

Lai, J. H., Chen, K. Y., Wu, J. C. C., Olson, L., Brené, S., Huang, C. Z., Chen, Y. H., Kang, S. J., Ma, K. H., Hoffer, B. J., Hsieh, T. H. & Chiang, Y. H., Oct 1 2019, In : Brain Research. 1720, 146301.

Research output: Contribution to journalReview article

Open Access
1 Citation (Scopus)
2018
6 Citations (Scopus)

A novel missense mutation of the GTP cyclohydrolase 1 gene in a Taiwanese family with dopa-responsive dystonia: A case report

Yang, C. C., Wang, W. C., Yeh, T. H., Chen, T. H., Liu, Y. L., Lu, M. K., Lu, C. S. & Tsai, C. H., Feb 1 2018, In : Clinical Neurology and Neurosurgery. 165, p. 21-23 3 p.

Research output: Contribution to journalArticle

Astrocytic CCAAT/Enhancer-binding protein delta contributes to reactive oxygen species formation in neuroinflammation

Wang, S. M., Lim, S. W., Wang, Y. H., Lin, H. Y., Lai, M. D., Ko, C. Y. & Wang, J. M., Jun 1 2018, In : Redox Biology. 16, p. 104-112 9 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)