Taipei Medical University

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    11031 Taipei

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2-(Phenylsulfonyl)quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase

Lee, H. Y., Chang, C. Y., Su, C. J., Huang, H. L., Mehndiratta, S., Chao, Y. H., Hsu, C. M., Kumar, S., Sung, T. Y., Huang, Y. Z., Li, Y. H., Yang, C. R. & Liou, J. P., Oct 21 2016, In : European Journal of Medicinal Chemistry. 122, p. 92-101 10 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

2007-2012年全國發展遲緩兒童通報概況

Translated title of the contribution: Overview of the Reporting of Developmentally-Delayed Children in Taiwan between 2007 and 2012Kang, C-W., Chen, C-L., 李俊毅(Jiun-Yih L & Tseng, S-H., 2014, In : 台灣復健醫學雜誌. 42, 2, p. 121-128 8 p.

Research output: Contribution to journalArticle

2010 Guidelines of the Taiwan society of cardiology for the management of hypertension

Chiang, C. E., Wang, T. D., Li, Y. H., Lin, T. H., Chien, K. L., Yeh, H. I., Shyu, K. G., Tsai, W. C., Chao, T. H., Hwang, J. J., Chiang, F. T. & Chen, J. H., Oct 2010, In : Journal of the Formosan Medical Association. 109, 10, p. 740-773 34 p.

Research output: Contribution to journalArticle

71 Citations (Scopus)

2016 Guidelines of the Taiwan Heart Rhythm Society and the Taiwan Society of Cardiology for the management of atrial fibrillation

Chiang, C. E., Wu, T. J., Ueng, K. C., Chao, T. F., Chang, K. C., Wang, C. C., Lin, Y. J., Yin, W. H., Kuo, J. Y., Lin, W. S., Tsai, C. T., Liu, Y. B., Lee, K. T., Lin, L. J., Lin, L. Y., Wang, K. L., Chen, Y-J., Chen, M. C., Cheng, C. C., Wen, M. S. & 7 others, Chen, W. J., Chen, J. H., Lai, W. T., Chiou, C. W., Lin, J. L., Yeh, S. J. & Chen, S. A., Nov 1 2016, In : Journal of the Formosan Medical Association. 115, 11, p. 893-952 60 p.

Research output: Contribution to journalArticle

51 Citations (Scopus)

2016年第13屆國際老年聯盟全球研討會活動紀實

徐慧娟(Hui-Chuan H, 2016, In : 人口學刊. 53, p. 183-189 7 p.

Research output: Contribution to journalArticle

2018 Guidelines of the Taiwan Society of Cardiology, Taiwan Society of Emergency Medicine and Taiwan Society of Cardiovascular Interventions for the management of non ST-segment elevation acute coronary syndrome

The Writing Group of 2018 Taiwan Guidelines for the Management of Non ST-segment Elevation Acute Coronary Syndrome, Sep 1 2018, In : Journal of the Formosan Medical Association. 117, 9, p. 766-790 25 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

2019 consensus statement of the Taiwan hypertension society and the Taiwan society of cardiology on renal denervation for the management of arterial hypertension

Wang, T. D., Lee, Y. H., Chang, S. S., Tung, Y. C., Yeh, C. F., Lin, Y. H., Pan, C. T., Hsu, C. Y., Huang, C. Y., Wu, C. K., Sung, P. H., Chiang, L. T., Wang, Y. C., Tsai, W. C., Lin, T. T., Lin, C. P., Chen, W. J. & Hwang, J. J., May 1 2019, In : Acta Cardiologica Sinica. 35, 3, p. 199-230 32 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

2019 focused update of the guidelines of the Taiwan society of cardiology for the diagnosis and treatment of heart failure

Wang, C. C., Wu, C. K., Tsai, M. L., Lee, C. M., Huang, W. C., Chou, H. H., Huang, J. L., Chi, N. H., Yen, H. W., Tzeng, B. H., Chang, W. T., Chang, H. Y., Wang, C. H., Lu, Y. Y., Tsai, J. P., Su, C. H., Cherng, W. J., Yin, W. H., Tsai, C. T., Wu, Y. W. & 2 others, Lin, J-L. & Hwang, J. J., May 1 2019, In : Acta Cardiologica Sinica. 35, 3, p. 244-283 40 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

2-Amino-3,4,5-Trimethoxybenzophenones as Potent Tubulin Polymerization Inhibitors

Chuang, H-Y., Chang, J-Y., Lai, M-J., Kuo, C-C., Lee, H. Y., Hsieh, H-P., Chen, Y-J., Chen, L-T., Pan, W-Y. & Liou, J. P., Mar 7 2011, In : ChemMedChem. 6, 3, p. 450-456 7 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

2-Amino and 2′-aminocombretastatin derivatives as potent antimitotic agents

Chang, J. Y., Yang, M. F., Chang, C. Y., Chen, C. M., Kuo, C. C. & Liou, J. P., Oct 2006, In : Journal of Medicinal Chemistry. 49, 21, p. 6412-6415 4 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition

Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J. Y., Liou, J. P. & Lee, H. Y., 2015, In : Organic and Biomolecular Chemistry. 14, 2, p. 716-723 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

2-Methoxyestradiol attenuates phosphatidylinositol 3-kinase/Akt pathway-mediated metastasis of gastric cancer

Lin, H. L., Yang, M. H., Wu, C. W., Chen, P. M., Yang, Y. P., Chu, Y. R., Kao, C. L., Ku, H. H., Lo, J. F., Liou, J. P., Chi, C. W. & Chiou, S. H., Dec 1 2007, In : International Journal of Cancer. 121, 11, p. 2547-2555 9 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

2-naphthol levels and allergic disorders in children

Lin, T-J., Guo, Y. L., Hsu, J. C. & Wang, I. J., Jul 9 2018, In : International Journal of Environmental Research and Public Health. 15, 7, 1449.

Research output: Contribution to journalArticle

2-Phenyl-5-(pyrrolidin-1-yl)-1-(3,4,5-trimethoxybenzyl)-1H-benzimidazole, a benzimidazole derivative, inhibits growth of human prostate cancer cells by affecting tubulin and c-Jun N-terminal kinase

Chang, W. L., Chang, C. S., Chiang, P. C., Ho, Y. F., Liu, J. F., Chang, K. W. & Guh, J. H., Aug 1 2010, In : British Journal of Pharmacology. 160, 7, p. 1677-1689 13 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

30 years follow-up and increased risks of breast cancer and leukaemia after long-term low-dose-rate radiation exposure

Hsieh, W. H., Lin, I. F., Ho, J. C. & Chang, P. W., Dec 5 2017, In : British Journal of Cancer. 117, 12, p. 1883-1887 5 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity

Lee, H-Y., Lee, J. F., Kumar, S., Wu, Y. W., HuangFu, W-C., Lai, M-J., Li, Y-H., Huang, H. L., Kuo, F. C., Hsiao, C. J., Cheng, C. C., Yang, C. R. & Liou, J-P., Jan 5 2017, In : European Journal of Medicinal Chemistry. 125, p. 1268-1278 11 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

3D scaffold with PCL combined biomedical ceramic materials for bone tissue regeneration

Chern, M. J., Yang, L. Y., Shen, Y. K. & Hung, J. H., 2013, In : International Journal of Precision Engineering and Manufacturing. 14, 12, p. 2201-2207 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)

3D影像電腦輔助設計合併兩片式手術模板正顎手術矯正治療之精準度分析: 前驅性研究

Translated title of the contribution: Accuracy of the Computer-Aided 3-D Virtual Planning System Combined with Double-Splint Design in the Orthognathic Surgery: A Pilot StudyLee, S-Y., 姜厚任 & 謝明吉, 2016, In : 中華民國齒顎矯正學雜誌. p. 152-162 11 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
7 Citations (Scopus)

3-OH flavone inhibition of epidermal growth factor-induced proliferaton through blocking prostaglandin E2 production

Shen, S. C., Ko, C. H., Hsu, K. C. & Chen, Y. C., Feb 4 2004, In : International Journal of Cancer. 108, 4, p. 502-510 9 p.

Research output: Contribution to journalArticle

35 Citations (Scopus)

3-O-methylquercetin more selectively inhibits phosphodiesterase subtype 3

Ko, W. C., Chen, M. C., Wang, S. H., Lai, Y. H., Chen, J. H. & Lin, C. N., Apr 1 2003, In : Planta Medica. 69, 4, p. 310-315 6 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

3′UTR polymorphisms of carbonic anhydrase IX determine the miR-34a targeting efficiency and prognosis of hepatocellular carcinoma

Hua, K. T., Liu, Y. F., Hsu, C. L., Cheng, T. Y., Yang, C. Y., Chang, J. S., Lee, W. J., Hsiao, M., Juan, H. F., Chien, M. H. & Yang, S. F., Dec 1 2017, In : Scientific Reports. 7, 1, 4466.

Research output: Contribution to journalArticle

23 Citations (Scopus)

4~8歲過動兒與正常兒童飲食攝取之比較

Translated title of the contribution: Dietary intakes of 4~8 years old children with attention-deficit hyperactivity disorderYang, S-C., Chiu, W-C., Chen, J-R., Lee, J. C. & Hsieh, M-C., 1999, In : Nutritional Sciences Journal. 24, 2, p. 153-165 13 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism-related enzymes gene polymorphisms, NNK metabolites levels and urothelial carcinoma

Chung, C. J., Pu, Y. S., Shiue, H. S., Lee, H. L., Lin, P., Yang, H. Y., Su, C-T. & Hsueh, Y-M., Jan 2013, In : Toxicology Letters. 216, 1, p. 16-22 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone is correlated with 8-hydroxy-2'-deoxyguanosine in humans after exposure to environmental tobacco smoke

Chiang, H. C., Huang, Y. K., Chen, P. F., Chang, C. C., Wang, C. J., Lin, P. & Lee, H. L., Jan 1 2012, In : Science of the Total Environment. 414, p. 134-139 6 p.

Research output: Contribution to journalArticle

12 Citations (Scopus)

45-60歲婦女之更年期症狀與生活品質相關因素研究

Huang, H-M., 趙湘台(Hsiang-Tai C, 林寬佳(Kuan-Chia L, Cheng, S-Y. & Liao, Y-M., 2010, In : 新臺北護理期刊. 12, 1, p. 7-20 14 p.

Research output: Contribution to journalArticle

4-Acetylantroquinonol B inhibits colorectal cancer tumorigenesis and suppresses cancer stem-like phenotype

Chang, T. C., Yeh, C-T., Adebayo, B. O., Lin, Y-C., Deng, L., Rao, Y. K., Huang, C. C., Lee, W. H., Wu, A. T. H., Hsiao, M., Wu, C. H., Wang, L. S. & Tzeng, Y. M., Oct 15 2015, In : Toxicology and Applied Pharmacology. 288, 2, p. 258-268 11 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

4-Acetylantroquinonol B suppresses autophagic flux and improves cisplatin sensitivity in highly aggressive epithelial cancer through the PI3K/Akt/mTOR/p70S6K signaling pathway

Liu, M., Bamodu, O. A., Huang, W. C., Zucha, M. A., Lin, Y. K., Wu, A. T. H., Huang, C. C., Lee, W. H., Yuan, C. C., Hsiao, M., Deng, L., Tzeng, Y. M. & Yeh, C. T., Mar 15 2017, In : Toxicology and Applied Pharmacology. p. 48-60

Research output: Contribution to journalArticle

8 Citations (Scopus)

4-acetyl-antroquinonol B suppresses SOD2-enhanced cancer stem cell-like phenotypes and chemoresistance of colorectal cancer cells by inducing hsa-miR-324 re-expression

Bamodu, O. A., Yang, C. K., Cheng, W. H., Tzeng, D. T. W., Kuo, K. T., Huang, C. C., Deng, L., Hsiao, M., Lee, W. H. & Yeh, C. T., Aug 10 2018, In : Cancers. 10, 8, 269.

Research output: Contribution to journalArticle

7 Citations (Scopus)

4- And 5-aroylindoles as novel classes of potent antitubulin agents

Liou, J. P., Wu, C. Y., Hsieh, H. P., Chang, C. Y., Chen, C. M., Kuo, C. C. & Chang, J. Y., Sep 6 2007, In : Journal of Medicinal Chemistry. 50, 18, p. 4548-4552 5 p.

Research output: Contribution to journalArticle

57 Citations (Scopus)

4-Bromophenylhydrazinyl benzenesulfonylphenylureas as indoleamine 2,3-dioxygenase inhibitors with in vivo target inhibition and anti-tumor efficacy

Lin, S. Y., Yeh, T. K., Song, J. S., Hung, M. S., Cheng, M. F., Liao, F. Y., Li, A. S., Cheng, S. Y., Lin, L. M., Chiu, C. H., Wu, M. H., Lin, Y. J., Hsiao, W., Sun, M., Wang, Y. H., Huang, C. H., Tang, Y. C., Chang, H. H., Huang, Z. T., Chao, Y. S. & 5 others, Shih, C., Pan, S. L., Wu, S. Y., Kuo, C. C. & Ueng, S. H., Apr 1 2018, In : Bioorganic Chemistry. 77, p. 600-607 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

4-Indolyl-N-hydroxyphenylacrylamides as potent HDAC class I and IIB inhibitors in vitro and in vivo

Mehndiratta, S., Wang, R. S., Huang, H. L., Su, C. J., Hsu, C. M., Wu, Y. W., Pan, S. L. & Liou, J. P., Jul 7 2017, In : European Journal of Medicinal Chemistry. 134, p. 13-23 11 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

4-O-Caffeoylquinic acid as an antioxidant marker for mulberry leaves rich in phenolic compounds

Ganzon, J. G., Chen, L. G. & Wang, C. C., 2018, In : Journal of Food and Drug Analysis.

Research output: Contribution to journalArticle

5 Citations (Scopus)

4β-Hydroxywithanolide E from Physalis peruviana (golden berry) inhibits growth of human lung cancer cells through DNA damage, apoptosis and G2/M arrest

Yen, C. Y., Chiu, C. C., Chang, F. R., Chen, J. Y., Hwang, C. C., Hseu, Y. C., Yang, H. L., Lee, A. Y. L., Tsai, M. T., Guo, Z. L., Cheng, Y. S., Liu, Y. C., Lan, Y. H., Chang, Y. C., Ko, Y. C., Chang, H. W. & Wu, Y. C., Feb 18 2010, In : BMC Cancer. 10, 46.

Research output: Contribution to journalArticle

67 Citations (Scopus)
6 Citations (Scopus)

500-Gray γ-Irradiation May Increase Adhesion Strength of Lyophilized Cadaveric Split-Thickness Skin Graft to Wound Bed

Wei, L. G., Chen, C. F., Wang, C. H., Cheng, Y. C., Li, C. C., Chiu, W. K. & Wang, H-J., Feb 3 2017, (Accepted/In press) In : Annals of Plastic Surgery.

Research output: Contribution to journalArticle

58-kDa microspherule protein (MSP58) is novel brahma-related gene 1 (BRG1)-associated protein that modulates p53/p21 senescence pathway

Hsu, C. C., Lee, Y. C., Yeh, S. H., Chen, C. H., Wu, C. C., Wang, T. Y., Chen, Y. N., Hung, L. Y., Liu, Y. W., Chen, H. K., Hsiao, Y. T., Wang, W. S., Tsou, J. H., Tsou, Y. H., Wu, M. H., Chang, W. C. & Lin, D. Y., Jun 29 2012, In : Journal of Biological Chemistry. 287, 27, p. 22533-22548 16 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

5-Amino-2-Aroylquinolines as highly potent tubulin polymerization inhibitors

Nien, C. Y., Chen, Y. C., Kuo, C. C., Hsieh, H. P., Chang, C. Y., Wu, J. S., Wu, S. Y., Liou, J. P. & Chang, J. Y., Mar 11 2010, In : Journal of Medicinal Chemistry. 53, 5, p. 2309-2313 5 p.

Research output: Contribution to journalArticle

63 Citations (Scopus)

5-Amino-2-aroylquinolines as highly potent tubulin polymerization inhibitors. Part 2. The impact of bridging groups at position C-2

Lee, H. Y., Chang, J. Y., Nien, C. Y., Kuo, C. C., Shih, K. H., Wu, C. H., Chang, C. Y., Lai, W. Y. & Liou, J. P., Dec 22 2011, In : Journal of Medicinal Chemistry. 54, 24, p. 8517-8525 9 p.

Research output: Contribution to journalArticle

42 Citations (Scopus)

5-Aminolevulinic acid induced photodynamic inactivation on Staphylococcus aureus and Pseudomonas aeruginosa

Hsieh, C. M., Huang, Y. H., Chen, C. P., Hsieh, B. C. & Tsai, T., 2014, In : Journal of Food and Drug Analysis. 22, 3, p. 350-355 6 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)

5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes

Lee, H. Y., Fan, S. J., Huang, F. I., Chao, H. Y., Hsu, K. C., Lin, T. E., Yeh, T. K., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Jan 29 2018, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

14 Citations (Scopus)

6,7-dihydroxy-2-(4′-hydroxyphenyl)naphthalene induces HCT116 cell apoptosis through activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway

Chiu, C. F., Lai, G. Y., Chen, C. H., Chiu, C. C., Hung, S. W. & Chang, C. F., Jan 1 2019, In : Drug Design, Development and Therapy. 13, p. 1609-1621 13 p.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

6-Acyl-4-aryl/alkyl-5,7-dihydroxycoumarins as anti-inflammatory agents

Lin, C. M., Huang, S. T., Lee, F. W., Kuo, H. S. & Lin, M. H., Jul 1 2006, In : Bioorganic and Medicinal Chemistry. 14, 13, p. 4402-4409 8 p.

Research output: Contribution to journalArticle

60 Citations (Scopus)

6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to trail-induced apoptosis via reactive oxygen species-mediated increase of dr5

Chen, C. Y., Tai, C. J., Cheng, J. T., Zheng, J. J., Chen, Y. Z., Liu, T. Z., Yiin, S. J. & Chern, C. L., May 12 2010, In : Journal of Agricultural and Food Chemistry. 58, 9, p. 5604-5611 8 p.

Research output: Contribution to journalArticle

23 Citations (Scopus)

7-Aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents

Chang, J. Y., Hsieh, H. P., Chang, C. Y., Hsu, K. S., Chiang, Y. F., Chen, C. M., Kuo, C. C. & Liou, J. P., Nov 16 2006, In : Journal of Medicinal Chemistry. 49, 23, p. 6656-6659 4 p.

Research output: Contribution to journalArticle

61 Citations (Scopus)
14 Citations (Scopus)

836 10-years experience in cystitis glandularis

Chang, C. H. C., Chen, K-K., Lin, T. L., Pan, C-C., Chang, Y-H., Huang, J., Kuo, J-Y., Chung, H-J. & Lin, T. L., Apr 1 2015, In : European Urology, Supplements. 14, 2, p. e836

Research output: Contribution to journalArticle

99mTc pyrene derivative complex causes double-strand breaks in dsDNA mainly through cluster-mediated indirect effect in aqueous solution

Chung, W. J., Cui, Y., Huang, F. Y. J., Tu, T. H., Yang, T. S., Lo, J. M., Chiang, C. S. & Hsu, I. C., Sep 22 2014, In : PLoS One. 9, 9, e108162.

Research output: Contribution to journalArticle

2 Citations (Scopus)