Taipei Medical University

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output 1958 2019

Granulosa Cells
Phosphatidylinositol 3-Kinases
2 Citations (Scopus)

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Inhibitory Concentration 50

A bioinspired hyperthermic macrophage-based polypyrrole-polyethylenimine (Ppy-PEI) nanocomplex carrier to prevent and disrupt thrombotic fibrin clots

Burnouf, T., Chen, C. H., Tan, S. J., Tseng, C. L., Lu, K. Y., Chang, L. H., Nyambat, B., Huang, S. C., Jheng, P. R., Aditya, R. N., Mi, F. L. & Chuang, E. Y., Jan 1 2019, In : Acta Biomaterialia.

Research output: Contribution to journalArticle


Abnormal Functional Relationship of Sensorimotor Network With Neurotransmitter-Related Nuclei via Subcortical-Cortical Loops in Manic and Depressive Phases of Bipolar Disorder

Martino, M., Magioncalda, P., Conio, B., Capobianco, L., Russo, D., Adavastro, G., Tumati, S., Tan, Z., Lee, H-C., Lane, T. J., Amore, M., Inglese, M. & Northoff, G., May 31 2019, In : Schizophrenia Bulletin. 12 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Neurotransmitter Agents
Raphe Nuclei
Basal Ganglia
Coronary Angiography
Optical Coherence Tomography
Return to Work
Appointments and Schedules
ROC Curve
Traumatic Brain Injury
Open Access
Health Services
Public Health
Cross-Sectional Studies
1 Citation (Scopus)

A Cross-Sectional Study of Endogenous Antioxidants and Patterns of Dental Visits of Periodontitis Patients

Lee, C. Y., Choy, C. S., Lai, Y. C., Chang, C. C., Teng, N. C., Huang, W. T., Lin, C. T. & Huang, Y. K., Jan 9 2019, In : International Journal of Environmental Research and Public Health. 16, 2

Research output: Contribution to journalArticle

Cross-Sectional Studies
Oral Health
1 Citation (Scopus)

Action of Reverse T3 on Cancer Cells

Lin, H. Y., Tang, H. Y., Leinung, M., Mousa, S. A., Hercbergs, A. & Davis, P. J., Jan 1 2019, In : Endocrine Research.

Research output: Contribution to journalArticle

Thyroid Hormone Receptors

Acupuncture treatment and the risk of urinary tract infection in stroke patients: a nationwide matched cohort study

Yang, J. L., Chen, T. L., Yeh, C. C., Hu, C. J., Liao, C. C., Lane, H. L. & Shih, C. C., Jan 1 2019, In : Acupuncture in Medicine.

Research output: Contribution to journalArticle

Acupuncture Therapy
Urinary Tract Infections
Cohort Studies

Acute exacerbations of chronic obstructive pulmonary disease (COPD) experiences among COPD patients with comorbid gastrooesophageal reflux disease

Lin, Y. H., Tsai, C. L., Tsao, L. I. & Jeng, C., May 1 2019, In : Journal of Clinical Nursing. 28, 9-10, p. 1925-1935 11 p.

Research output: Contribution to journalArticle

Gastroesophageal Reflux
Chronic Obstructive Pulmonary Disease
Disease Progression
Medical Assistance
Qualitative Research

Adaptation and Validation of Alternative Healthy Eating Index in Hemodialysis Patients (AHEI-HD) and Its Association with all-Cause Mortality: A Multi-Center Follow-Up Study

Van Duong, T., Tseng, I. H., Wong, T. C., Chen, H. H., Chen, T. H., Hsu, Y. H., Peng, S. J., Kuo, K. L., Liu, H. C., Lin, E. T., Feng, Y. W. & Yang, S. H., Jun 21 2019, In : Nutrients. 11, 6

Research output: Contribution to journalArticle

Open Access
healthy diet
Renal Dialysis
nutritional adequacy

A decline in the prevalence of angina pectoris: Data from the Nutrition and Health Survey in Taiwan

Tsai, C. C., Hsieh, I. C., Jeng, C., Ho, L. H., Chu, P. H. & Chuang, S. Y., Apr 1 2019, In : International Journal of Cardiology. 280, p. 1-7 7 p.

Research output: Contribution to journalArticle

Nutrition Surveys
Angina Pectoris
Health Surveys
Heart Diseases

Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis

Jan, Y. H., Lai, T. C., Yang, C. J., Lin, Y. F., Huang, M. S. & Hsiao, M., Jan 29 2019, In : Journal of Hematology and Oncology. 12, 1, 12.

Research output: Contribution to journalArticle

Adenylate Kinase
Oxidative Stress
Neoplasm Metastasis
Lung Neoplasms
Epithelial-Mesenchymal Transition

Adipose-derived Stem Cells Attenuates Diabetic Osteoarthritis via Inhibition of Glycation-mediated Inflammatory Cascade

Dubey, N. K., Wei, H-J., Yu, S. H., Williams, D. F., Wang, J. R., Deng, Y. H., Tsai, F. C., Wang, D. P. & Deng, W-P., 2019, In : Aging and Disease.

Research output: Contribution to journalArticle

Stem Cells
Knee Joint
Advanced Glycosylation End Products
NF-kappa B
1 Citation (Scopus)
Open Access
smooth muscle
1 Citation (Scopus)

A double-virally-inactivated (Intercept–solvent/detergent) human platelet lysate for in vitro expansion of human mesenchymal stromal cells

Barro, L., Su, Y. T., Nebie, O., Wu, Y. W., Huang, Y. H., Koh, M. B. C., Knutson, F. & Burnouf, T., Jan 1 2019, In : Transfusion.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Blood Platelets
In Vitro Techniques
Hip Fractures
Cohort Studies
International Classification of Diseases

Advanced glycosylated end products restrain the osteogenic differentiation of the periodontal ligament stem cell

Guo, Z. L., Gan, S. L., Cao, C. Y., Fu, R., Cao, S. P., Xie, C., Chen, J. W., Gibson, A., Zheng, X. & Teng, N. C., Jan 1 2019, In : Journal of Dental Sciences.

Research output: Contribution to journalArticle

Open Access
Periodontal Ligament
Stem Cells
Third Molar
Periodontal Diseases

Adverse Outcomes after Major Surgeries in Patients with Diabetes: A Multicenter Matched Study

Lin, C-S., Chang, C-C., Lee, Y-W., Liu, C-C., Yeh, C-C., Chang, Y-C., Chuang, M-T., Chang, T-H., Chen, T-L. & Liao, C-C., Jan 16 2019, In : Journal of Clinical Medicine. 8, 1

Research output: Contribution to journalArticle

Multicenter Studies
Odds Ratio
Confidence Intervals
Hospital Mortality
Necrotizing Fasciitis

Adverse stroke outcomes among patients with bipolar disorder

Chen, P. H., Kao, Y. W., Shia, B. C., Lin, H. C. & Kang, J. H., Mar 1 2019, In : PLoS One. 14, 3, e0213072.

Research output: Contribution to journalArticle

Open Access
Bipolar Disorder
Length of Stay
Hospital Mortality
2 Citations (Scopus)
Job Satisfaction
Social Change

A high linoleic acid diet exacerbates metabolic responses and gut microbiota dysbiosis in obese rats with diabetes mellitus

Lee, H. C., Yu, S. C., Lo, Y. C., Lin, I. H., Tung, T. H. & Huang, S. Y., Feb 1 2019, In : Food and Function. 10, 2, p. 786-798 13 p.

Research output: Contribution to journalArticle

Linoleic Acid
diabetes mellitus
intestinal microorganisms
linoleic acid

Alteration in iron efflux affects male sex hormone testosterone biosynthesis in a diet-induced obese rat model

Kurniawan, A. L., Lee, Y. C., Shih, C. K., Hsieh, R. H., Chen, S. H. & Chang, J. S., Jul 1 2019, In : Food and Function. 10, 7, p. 4113-4123 11 p.

Research output: Contribution to journalArticle

Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization

Chen, W-T., Hsu, W-T., Yen, M-H., Changou, C. A., Han, C-L., Chen, Y-J., Cheng, J-Y., Chang, T-H., Lee, O. K-S. & Ho, J. H-C., Jan 1 2019, In : Biomaterials. 190-191, p. 1-10 10 p.

Research output: Contribution to journalArticle

Cell Polarity
Stem cells
Mesenchymal Stromal Cells
Shear stress
Air Pollution
Pleural Effusion

Altered frontal aslant tracts as a heritable neural basis of social communication deficits in autism spectrum disorder: A sibling study using tract-based automatic analysis

Lo, Y. C., Chen, Y. J., Hsu, Y. C., Chien, Y. L., Gau, S. S. F. & Tseng, W. Y. I., 2019, In : Autism Research.

Research output: Contribution to journalArticle

Diffusion Magnetic Resonance Imaging
2 Citations (Scopus)

Altered Global Signal Topography and Its Different Regional Localization in Motor Cortex and Hippocampus in Mania and Depression

Zhang, J., Magioncalda, P., Huang, Z., Tan, Z., Hu, X., Hu, Z., Conio, B., Amore, M., Inglese, M., Martino, M. & Northoff, G., Jun 18 2019, In : Schizophrenia Bulletin. 45, 4, p. 902-910 9 p.

Research output: Contribution to journalArticle

Motor Cortex
Bipolar Disorder
Episodic Memory

Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5-diamino-6-chloro-N-(N-(2,6-dichlorobenzoyl)carbamimidoyl)pyrazine-2-carboxide

Lee, C. C., Chang, W. H., Chang, Y. S., Yang, J. M., Chang, C. S., Hsu, K. C., Chen, Y. T., Liu, T. Y., Chen, Y. C., Lin, S. Y., Wu, Y. C. & Chang, J. G., Jan 1 2019, In : Molecular Oncology.

Research output: Contribution to journalArticle

Open Access

A machine learning approach for predicting urine output after fluid administration

Lin, P. C., Huang, H. C., Komorowski, M., Lin, W. K., Chang, C. M., Chen, K. T., Li, Y. C. & Lin, M. C., Aug 1 2019, In : Computer Methods and Programs in Biomedicine. 177, p. 155-159 5 p.

Research output: Contribution to journalArticle

Learning systems

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Shen, T. J., Jhan, M. K., Kao, J. C., Ho, M. R., Tsai, T. T., Tseng, P-C., Wang, Y. T. & Lin, C-F., 2019, In : Journal of Visualized Experiments.

Research output: Contribution to journalArticle

Viral Encephalitis
Dengue Virus
Severe Dengue
2 Citations (Scopus)

Analysis of Electroencephalography Event-Related Desynchronisation and Synchronisation Induced by Lower-Limb Stepping Motor Imagery

Liu, Y. H., Lin, L. F., Chou, C. W., Chang, Y., Hsiao, Y. T. & Hsu, W. C., Feb 6 2019, In : Journal of Medical and Biological Engineering. 39, 1, p. 54-69 16 p.

Research output: Contribution to journalArticle

Stepping motors

An artificial intelligence approach to early predict non-ST-elevation myocardial infarction patients with chest pain

Wu, C. C., Hsu, W. D., Islam, M. M., Poly, T. N., Yang, H. C., Nguyen, P. AA., Wang, Y. C. & Li, Y. CJ., May 1 2019, In : Computer Methods and Programs in Biomedicine. 173, p. 109-117 9 p.

Research output: Contribution to journalArticle

Artificial Intelligence
Chest Pain
Artificial intelligence
Neural networks
Neural Networks (Computer)

An Assessment of the Interoperability of Electronic Health Record Exchanges Among Hospitals and Clinics in Taiwan

Wen, H-C., Chang, W-P., Hsu, M-H., Ho, C-H. & Chu, C. M., Mar 28 2019, In : JMIR medical informatics. 7, 1, p. e12630

Research output: Contribution to journalArticle

Electronic Health Records
National Health Programs
Medical Records
2 Citations (Scopus)

Androgen deprivation-induced ZBTB46-PTGS1 signaling promotes neuroendocrine differentiation of prostate cancer

Chen, W. Y., Zeng, T., Wen, Y. C., Yeh, H. L., Jiang, K. C., Chen, W. H., Zhang, Q., Huang, J. & Liu, Y. N., Jan 1 2019, In : Cancer Letters. 440-441, p. 35-46 12 p.

Research output: Contribution to journalArticle

Prostaglandin-Endoperoxide Synthases
Prostatic Neoplasms
Cyclooxygenase Inhibitors
Androgen Receptors
Open Access
Gastric Parietal Cells

An evaluation of pitavastatin for the treatment of hypercholesterolemia

Chan, P., Shao, L., Tomlinson, B., Zhang, Y. & Liu, Z. M., Jan 2 2019, In : Expert Opinion on Pharmacotherapy. 20, 1, p. 103-113 11 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
LDL Cholesterol
Expert Testimony

Angiotensin-converting enzyme inhibitors or angiotensin receptor blocker monotherapy retard deterioration of renal function in Taiwanese chronic kidney disease population

Zheng, C. M., Wang, J. Y., Chen, T. T., Wu, Y. C., Wu, Y. L., Lin, H. T., Chiu, S. P., Chang, T. J., Zheng, J. Q., Chu, N. F., Lin, Y. M., Su, S. L., Lu, K. C., Chen, J. S., Sung, F. C., Lee, C. T., Yang, Y., Hwang, S. J., Wang, M. C., Hsu, Y. H. & 4 others, Chiou, H. Y., Kao, S., Wu, M. Y. & Lin, Y. F., Dec 1 2019, In : Scientific Reports. 9, 1, 2694.

Research output: Contribution to journalArticle

Open Access
Angiotensin Receptor Antagonists
Chronic Renal Insufficiency
Angiotensin-Converting Enzyme Inhibitors
Open Access
Electronic Health Records
Human Influenza
Centers for Disease Control and Prevention (U.S.)

An Open-Label, Multicenter, Phase I, Dose Escalation Study with Phase II Expansion Cohort to Determine the Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Intravenous TKM-080301 in Subjects with Advanced Hepatocellular Carcinoma

El Dika, I., Lim, H. Y., Yong, W. P., Lin, C. C., Yoon, J. H., Modiano, M., Freilich, B., Choi, H. J., Chao, T. Y., Kelley, R. K., Brown, J., Knox, J., Ryoo, B. Y., Yau, T. & Abou-Alfa, G. K., Jan 1 2019, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Open Access
Maximum Tolerated Dose
Hepatocellular Carcinoma
Small Interfering RNA
4 Citations (Scopus)

A novel injectable in situ forming gel based on carboxymethyl hexanoyl chitosan/hyaluronic acid polymer blending for sustained release of berberine

Lu, K. Y., Lin, Y. C., Lu, H. T., Ho, Y. C., Weng, S. C., Tsai, M. L. & Mi, F. L., Feb 15 2019, In : Carbohydrate Polymers. 206, p. 664-673 10 p.

Research output: Contribution to journalArticle

Hyaluronic acid
Hyaluronic Acid

Antagonism of Ca 2+ -sensing receptors by NPS 2143 is transiently masked by p38 activation in mouse brain bEND.3 endothelial cells

Chen, C. Y., Hour, M. J., Lin, W. C., Wong, K. L., Shiao, L. R., Cheng, K. S., Chan, P. & Leung, Y. M., Jan 1 2019, In : Naunyn-Schmiedeberg's Archives of Pharmacology.

Research output: Contribution to journalArticle

Calcium-Sensing Receptors
Endothelial Cells
Cardiovascular Agents

Antecedent Administration of Glutamine Benefits the Homeostasis of CD4+ T Cells and Attenuates Lung Injury in Mice With Gut-Derived Polymicrobial Sepsis

Lei, C. S., Wu, J. M., Lee, P. C., Kuo, T. C., Chen, P. D., Hou, Y. C., Yeh, S. L. & Lin, M. T., Jan 1 2019, In : Journal of Parenteral and Enteral Nutrition.

Research output: Contribution to journalArticle

Lung Injury

Antidepressant use and hepatocellular carcinoma in patients with hepatitis C who had received interferon therapy: A population-based cohort study

Chen, V. C. H., Lu, M. L., Yang, Y. H., Weng, J. C. & Chang, C. C., Jun 15 2019, In : Journal of Affective Disorders. 253, p. 147-153 7 p.

Research output: Contribution to journalArticle

Hepatitis C
Antidepressive Agents
Hepatocellular Carcinoma
Cohort Studies
Single-Chain Antibodies
Escherichia coli
Amino Acids
OMPA outer membrane proteins
2 Citations (Scopus)

Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo

Hsieh, Y. L., Tu, H. J., Pan, S. L., Liou, J. P. & Yang, C. R., Jun 1 2019, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 6, p. 992-1003 12 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Histone Deacetylase Inhibitors
Breast Neoplasms
Histone Deacetylases
1 Citation (Scopus)

Antimetastatic effects of Terminalia catappa leaf extracts on cervical cancer through the inhibition of matrix metalloprotein-9 and MAPK pathway

Lee, C. Y., Yang, S. F., Wang, P. H., Su, C. W., Hsu, H. F., Tsai, H. T. & Hsiao, Y. H., Jan 1 2019, In : Environmental Toxicology. 34, 1, p. 60-66 7 p.

Research output: Contribution to journalArticle

Uterine Cervical Neoplasms
Open Access
Klebsiella pneumoniae
Pseudomonas aeruginosa
Intensive Care Units