Taipei Medical University

Projects

Projects per year 2002 2013 2014 2015 2016 2017 2018 2019 2020 2021 2024

• 2 Not started
• 829 Active
• 6002 Finished

Projects per year

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• b - Ministry of Science and Technology

  有機金屬催化反應於合成化學和藥物化學之抗癌表觀遺傳學抑制劑研究(2/2)

  Liou, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 失眠症患者使用中西醫醫療利用之長期趨勢分析

  Chien, L.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• ERK/p65及p300在Pref-1誘導肺部纖維母細胞CTGF表現之研究

  Chen, B.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 打造即時「同理心溫度計」協助醫病互動(1/2)

  Li, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討pan-HDACs 抑制劑對抗藥性腦癌的抑制療效和作用機轉

  Hsu, K.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Lysine-specific histone demethylase 1 抑制劑的研發

  Liou, J.

  2/1/20 → 1/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 小分子抗前列腺癌之藥物研發

  Liou, J.

  6/1/16 → 4/30/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 在慢性阻塞性氣喘中double cortin like kinase 1 (DCLK1)在thrombin誘導IL-8/CXCL8表現及氣道發炎的病理角色之研究(2/3)

  Chen, B.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性選擇性HDAC抑制劑之抗癌藥物開發與藥理機轉探討(3/3)

  Pan, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究ADAM10/Notch1調控TGF-β誘導肺部上皮細胞CTGF表現之分子機轉探討

  Chen, B.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討檸檬香蜂草水萃物誘導大腸癌細胞鐵依賴性細胞死亡之抗腫瘤機轉

  Huang, T.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Association Study of Genetic Polymorphisms of Toll-Like Receptors on Ischemic Stroke (I)

  Chiou, H.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of Regioselective Substitution on 1,4-Benzoquinone Derivatives to Provide Potent Anticancer Agents

  Liou, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 1,4-benzoquinone 100%
  • Wittig Olefination 54%
  • Intramolecular Cyclization 40%
  • Nucleophilic Substitution 38%
  • Regioselectivity 35%

• The Role of ADAM 17 in Hypoxia-Induced CTGF Expression and Pulmonary Fibrosis (I)

  Chen, B.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Publication of Journal of Biomedical Science

  Chang, W.

  1/1/11 → 12/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Scholarly Communication 100%
  • Taiwan 99%
  • Publications 83%
  • Biological Science Disciplines 62%
  • Information Dissemination 59%

• Role of Sp-Family in Lung Tumorigenesis

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lung 100%
  • Lung Neoplasms 73%
  • Carcinogenesis 61%
  • Doxycycline 61%
  • Neoplasms 43%

• The First Randomized Controlled Clinical Trial for Computerized Decision Support System (II)

  Li, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Contrast Media 100%
  • Drug-Related Side Effects and Adverse Reactions 60%
  • Clinical Decision Support Systems 56%
  • Physicians 54%
  • Randomized Controlled Trials 43%

• Drug Discovery and Pharmacological Study of Novel pan-HDAC Inhibitors as Anti-Angiogenic Drugs

  Pan, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylase Inhibitors 100%
  • Histone Deacetylases 36%
  • Drug Discovery 23%
  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 18%
  • Animal Models 16%

• Study of Anti-Αlpha-Enolase I Antibodies on Cancers and Their Potential Applications

  Yang, Y. & Leu, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphopyruvate Hydratase 100%
  • Antibodies 32%
  • Single-Chain Antibodies 13%
  • Neoplasms 10%
  • Proteins 9%

• Functional Role of Growth Factor-Induced Metabolic Enzymes Expression in Cancer Cell Anti-Oxidation and Drug Resistance

  Chang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epidermal Growth Factor 100%
  • Enzymes 83%
  • Neoplasms 82%
  • Drug Resistance 46%
  • Carcinogenesis 39%

• Novel Roles of Arnt in Breast Tumor Progression, Metastasis and Therapy

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Epidermal Growth Factor 100%
  • Neoplasms 65%
  • Arachidonate 12-Lipoxygenase 45%
  • Neoplasm Metastasis 45%
  • Xenobiotics 32%

• Role of Sp-family in lung tumorigenesis

  Chang, W.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lung 100%
  • Lung Neoplasms 73%
  • Carcinogenesis 61%
  • Doxycycline 61%
  • Neoplasms 43%

• To See Is to Believe- Visualization of the Spectrum on Chronic Kidney Disease (II)

  Jian, W., Li, Y. & Wu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Health care 100%
  • Data visualization 75%
  • Patient treatment 50%
  • Disease control 49%
  • Health insurance 49%

• The Role of ADAM 17 in Hypoxia-Induced CTGF Expression and Pulmonary Fibrosis (III)

  Chen, B.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • ADAM17 Protein 100%
  • Connective Tissue Growth Factor 83%
  • Hypoxia 49%
  • Small Interfering RNA 38%
  • Fibrosis 21%

• 新穎性pan-HDAC 抑制劑抑制血管新生之藥物研發與藥理作用機轉(3/3)

  Pan, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylase Inhibitors 100%
  • Histone Deacetylases 49%
  • 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxyacrylamide 20%
  • Animal Models 18%
  • Drug Discovery 17%

• 探討小分子核糖核酸和腸道微生物在中風後血管性認知功能障礙所扮演的角色(3/3)

  Chiou, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Establishment of Screening Platform by Novel Bio-Markers of Clinical Osteoporosis and Development of Taiwanese Native Plants in Bone Remodeling: in Vivo and in Vitro Study

  Lee, M.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Establishment of Screening Platform by Novel Bio-Markers of Clinical Osteoporosis and Development of Taiwanese Native Plants in Bone Remodeling: in Vivo and in Vitro Study(3/3)

  Lee, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study Clinical Feasibility of Cdk Iv Inhibitor for Pediatric Malignant Brain Tumors Treatment(1/3)

  Hsieh, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 產學合作計畫－開發千根草於調控骨頭再塑產品之應用

  Lee, M.

  11/1/20 → 10/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 藉由全方位探索新致病機制發現新的第2型糖尿病之肝臟治療靶點：基於慢性C型肝炎病毒感染模式到一般族群、連結基礎，生物信息學和臨床的系統性探討之轉譯研究－整合生物資訊方法研究C型肝炎誘發之第二型糖尿病的機轉與藥物開發(1/3)

  Hsu, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以小分子甲殼素奈米粒子建構水生魚類的核酸運輸平台

  Cheng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Involvement of Genes Encoding Apoptosis Regulatory Pathway in the Pathogenesis of Hyperglycemia in Acute Ischemic Stroke

  Hsieh, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Involvement of Genes Encoding Apoptosis Regulatory Pathway in the Pathogenesis of Hyperglycemia in Acute Ischemic Stroke

  Hsieh, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 噬菌體展現技術製備之辨識蛇毒蛋白的雞源單鏈抗體之分析與人源化研究

  Yang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研發新穎性 MAP3K9 抑制劑並探討其對胰臟癌之抗癌機轉

  Pan, S.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 產學合作開發嶄新抗體藥物之平台（3/3）

  Yang, Y.

  2/1/15 → 1/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎性DYRK1A抑制劑於阿茲海默症之機轉探討(3/3)

  HuangFu, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Radiogenomic Mapping of Angiogenesis in Glioblastoma

  Hsieh, K. L.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glioblastoma 100%
  • Phenotype 30%
  • Survival 28%
  • Multiparametric Magnetic Resonance Imaging 23%
  • Genetic Profile 21%

• 生命科技群組政府科技發展計畫規劃及審議之研究

  Chang, W.

  1/1/15 → 12/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Role of Transcription Factor Sp1 in Brain Neuronal Injury (II)

  Chang, W.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Investigate the Role of Rbm3 in Therapeutic Hypothermia Mediated Neuroprotection in Ischemia Stroke(2/3)

  Yang, C. H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Transgenerational Epigenetic Reprogramming of Neuronal Maturation by Early-Life Maternal Sleep Deprivation( I )

  Yang, C. H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Maternal Deprivation 100%
  • Sleep Deprivation 86%
  • Epigenomics 63%
  • Sleep 32%
  • Puberty 22%

• To Investigate the Role of Rbm3 in Therapeutic Hypothermia Mediated Neuroprotection in Ischemia Stroke(3/3)

  Yang, C. H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Relationships of One-Carbon Cycle Pathways with Psychopathology and Metabolic Abnormalities in Patients with Schizophrenia and Potential Intervention Strategy with 5-Methyltetrahydrofolate and Vitamin B12(3/3)

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Folic Acid 100%
  • Vitamin B 12 69%
  • Carbon Cycle 66%
  • Schizophrenia 51%
  • 5-methyltetrahydrofolate 48%

• The Impact of Chronic Sleep Deprivation on Neurocognition, Mood and Stress Regulation among Adolescents: Observational Follow-Up and Intervention Studies of Healthy Adolescent Cohorts( I )

  Lee, H. & Chiu, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effect of Wnt Signals and Programmed Cell Death on the Organization of Neural Circuit in Spinal Motor Neurons

  Kao, T.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Motor Neurons 100%
  • Wnt Receptors 73%
  • Ephrins 46%
  • Nerve Growth Factors 42%
  • Growth Cones 40%

• The Synergistic Integration of Ephrin and Netrin Signals in the Developing Nervous System

  Kao, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Netrins 100%
  • Growth Cones 95%
  • Ephrins 91%
  • Motor Neurons 60%
  • Ephrin-B2 41%

• Predictions of Therapeutic Effects of Zolpidem in Disorders of Consciousness Patients(1/3)

  Lane, T. J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Trajectory and Biomarkers for Post-Stroke Cognitive Impairment(1/3)

  Hu, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology