Taipei Medical University

Projects

Projects per year 2002 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 3 Not started
• 603 Active
• 7294 Finished

Projects per year

Search results

• b - Ministry of Science and Technology

  Role and Molecular Mechanisms of N-Α-Acetyltransferase in Driving Tumor Invasion and Metastasis of Osteosarcoma

  Chien, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • osteosarcoma 100%
  • gelatinase A 66%
  • metastasis 59%
  • neoplasms 30%
  • acetyltransferases 21%

• Developing Therapeutic Mesoporous Silica Nanoparticles for Neurodegenerative Diseases

  Chen, Y.

  1/1/18 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Silicon Dioxide 100%
  • Nanoparticles 78%
  • Neurodegenerative Diseases 42%
  • Blood-Brain Barrier 28%
  • Genetic Therapy 18%

• Application of High-Throughput Sequencing Approaches in Immunogenomic Research : Diversity and Clonal Selection in the Human T-Cell Repertoire for Colonrectal Cancers

  Chang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • T-Cell Antigen Receptor 54%
  • V(D)J Recombination 52%
  • T-Lymphocytes 44%
  • Neoplasms 28%

• Amyloid and Neuroinflammation in Vascular Dementia Animal Model

  Hu, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Amyloid 100%
  • Cognitive Dysfunction 86%
  • Blood Vessels 62%
  • Alzheimer Disease 51%
  • Stroke 45%

• The Potential Role of Glycogen Synthase Kinase-3 in Dengue Virus-Infected Mononuclear Phagocytes

  Lin, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycogen Synthase Kinase 3 100%
  • Dengue Virus 93%
  • Virus Diseases 47%
  • Interleukin-10 35%
  • Cellular Immunity 28%

• Genetic Polymorphisms of Estrogen Genes in Young Ischemic Stroke (III)

  Chiou, H., Lin, H., Hu, C. & Bai, C.

  12/1/10 → 11/30/11

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of indoor air quality improvement on cardiovascular health in general population

  Chuang, K.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Indoor Air Pollution 100%
  • Air Pollution 15%
  • Taiwan 13%
  • Cardiovascular System 13%
  • Quality Improvement 13%

• Effects of Exercise Training on Sleep Disturbances, Anxiety, and Depression among Newly Diagnosed Elderly Lung Cancer Patients

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Building The Big Data Database of Technological Innovation, Research and Development (Ⅱ)

  Shia, B.

  3/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用基因網絡分析尋找假定蛋白質 （hypothetical protein)與抗藥性的關係

  Wu, Y.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 奈米HEVnp於晚期大腸直腸癌患者的治療策略(2/3)

  Whang-Peng, J.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Benefical Effects and Mechanisms of Probiotics and Exercise Intervention Strategies in 6-Ohda Induced Parkinson'S Disease Rat(1/3)

  Huang, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Probiotics 100%
  • Oxidopamine 81%
  • Parkinson Disease 39%
  • Substantia Nigra 25%
  • Gastrointestinal Microbiome 23%

• 利用大型基因資料庫及臨床收案，探討台灣族群ITPKC基因變異在氣喘之角色

  Chang, W.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 鑑定癌症幹細胞抑制劑(2/3)

  Whang-Peng, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 隨機模型於精準健康科學之應用-生物資訊隨機過程於精準健康科學之應用(3/3)

  Chen, L.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• DeepNLP-DNA：運用深度編解碼架構及二維卷積神經網路以分析去氧核糖核酸序列表現之預先訓練自然語言處理模型研究(2/2)

  Le, N. Q. K.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 椰糖對葡聚醣硫酸鈉（DSS）誘發結腸炎大鼠的影響

  Shih, C.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Verify Cd44 and Arpc2 Expressions in Gbm of Different Brain Lobes via Tissue Array Identifies Cd44/Arpc2 Regulate Radioresistance and Radiomics of Gbm in Different Brain Lobes to Build up Radiogenomics and Develop Ai for Personally Precise Medicine.

  Lin, J.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Large Series of Clinical and Imaging Investigation to Patients with Chronic Lower Limb Edema with Unclear Etiology

  Chan, W. P.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phlebography 100%
  • Edema 47%
  • Lower Extremity 36%
  • Angiography 15%
  • Leg 10%

• A Novel Porcine Bone Xenograft Development

  Chang, W.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • bones 100%
  • dentistry 66%
  • testing 36%
  • skeletal development 31%
  • biocompatibility 27%

• Cellular and Molecular Mechanisms of Oxidative Stress and Anti-Oxidant Agents on the Electrophysiology and Calcium Regulation in Atrium and Pulmonary Vein Cardiomyocytes

  Chen, Y.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • cardiomyocytes 100%
  • lungs 91%
  • atrial fibrillation 80%
  • calcium 66%
  • oxidative stress 58%

• The Investigation of Anti-Neuroinflammatory Mechanisms of Differential Histone Deacetylase Regulators and Their Therapeutic Profiles in Experimental Intracerebral Haemorrahge and Encephalitis

  Hsiao, G.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Encephalitis 100%
  • Monocytes 77%
  • Acetylation 73%
  • Microglia 71%
  • Psychological Inhibition 57%

• Preclinical Assessment of the Potential Prognostic and Therapeutic Values of Hippo Signaling Cascade in Targeting Therapy-Resistant Cancer Stem Cells in Hepatocellular Carcinoma

  Lee, W.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Neoplastic Stem Cells 29%
  • Liver 28%
  • Neoplasms 22%
  • Side-Population Cells 20%

• Evaluations of Anti-Photoaging, Anti-Melanogenesis and Transdermal Delivery of Safflower Yellow

  Chien, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • hydroxysafflor yellow A 100%
  • safflower yellow 48%
  • Carthamus tinctorius 26%
  • Skin 22%
  • Skin Absorption 21%

• Reflecting on Issues of End-Of-Life by Approaching Ventilator-Dependent Patients: an Interdisciplinary Educational Action Research

  Chen, C., Lin, W., Lin, S. & Tang, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • team teaching 100%
  • action research 70%
  • curriculum 64%
  • medicine 57%
  • dialogue 56%

• 選擇性抗癌標靶藥物HDAC6抑制劑臨床前試驗研究(II)

  Pan, S.

  5/1/19 → 1/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploring Gene-Lifestyle Factors of Childhood Obesity, Pubertal Development, and Insulin Resistance(2/3)

  Chen, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 行人低頭族風險行為探討: 以虛擬擴增實境遊戲、賽車遊戲為例

  Pai, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of a Program of Mind-Body Interventions on Psychological Resilience, Vagal Tone, Emotional States, and Outcomes of Heart Failure

  Tsai, P.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heart Failure 100%
  • Psychological Resilience 61%
  • Anxiety 56%
  • Depression 51%
  • Heart Rate 42%

• Genetic Polymorphisms of Calcium Channel in the Risk of Breast Cancer

  Chang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Calcium Channels 63%
  • Breast Neoplasms 60%
  • Genetic Polymorphisms 37%
  • Calcium 24%
  • Case-Control Studies 18%

• 睡眠困擾是癌症病人最常主訴的問題之一。患有睡眠困擾之癌症病人經常同時伴隨 疲憊、憂鬱等現象發生，形成症狀群集，影響生活品質。雖然目前對於癌症病人睡眠障 礙之量性研究已多有著墨，然而對於癌症病人經歷睡眠障礙之主觀經驗之瞭解，仍相當 有限。瞭解病人經歷睡眠障礙之主觀經驗，將有助於未來睡眠評估工具之修訂。另外， 在評估癌症病人睡眠品質時，若能以簡單工具評估，會更具效率及助益。阿森斯失眠量 表(Athens Insomnia Scale, AIS) 是一個簡單的8 題問卷，廣為使用在一般失眠的病人， 在癌症病人使用上，尚未有豐富的實證資料，若能建立其在癌症病人的信效度，將可作 為一簡單篩檢癌症病人失眠的工具。 睡眠遵行日夜節律規則，日夜節律又需要光作為矯正的線索，光在癌症病人睡眠的 角色，尚未有研究證實，過去研究顯示癌症病人睡眠品質不佳與生物節律有關係。光是 重要日夜節律的線索，光療法透過褪黑激素調節，調整日夜節律週期，可能可以改善睡 眠品質。另外，由於，睡眠障礙、憂鬱、疲憊經常形成一症狀群集，光療法於改善睡眠 障礙之同時，是否亦同時改善憂鬱、疲憊及生活品質。目前，光療法在癌症病人的運用 上，付之闕如，故建立光療法於癌症病人的有效性值得探究。 本研究為三年期研究計畫，目的包括有：1.瞭解癌症個案對於睡眠困擾的主觀經驗 （第一年）。2.建立阿森斯失眠量表中文版的信效度、敏感性、特異性（第一年）。3.瞭 解癌症病人光暴露與生物節率、睡眠障礙的關係（第二年）。4.瞭解光療法對於改善癌 症病人睡眠障礙及相關症狀群集、及生活品質之成效；以及瞭解光療法影響褪黑激素之 程度（第三年）。 本研究擬以癌症住院及門診病人為對象，研究工具包括基本資料、匹茲堡睡眠品質 問卷、阿森斯失眠問卷，簡明疲憊量表，貝克憂鬱量表度、SF-36 生活品質量表、腕動 力器等。資料處理分析方式包括：內容分析、描述性統計、t 檢定、皮爾森相關、GEE (generalized estimating equations)等。 本研究之結果將可瞭解光暴露與生物節率與睡眠障礙之間的關係，並可進一步瞭解 光療法作為改善癌症病人睡眠障礙之護理措施之成效，以期，最終能藉由改善癌症病人 之睡眠品質提昇病人之生活品質。

  Lin, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sleep 100%
  • Phototherapy 34%
  • Neoplasms 25%
  • Sleep Initiation and Maintenance Disorders 22%
  • Light 15%

• Dementia Care and Quality Improvement

  Chien, L., Chiou, H., Chi, N. & Hu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • dementia 100%
  • health insurance 28%
  • Medical records 19%
  • utilization 17%
  • resources 9%

• Effects of fish oil on alcoholic liver disease in rats based on pathological mechanisms

  Yang, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • liver diseases 100%
  • alcohol abuse 83%
  • fish oils 81%
  • liver function 46%
  • rats 39%

• The Effect of Health Risk Behaviors on Recurrent Traffic Injury

  Chen, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Health risks 100%
  • Risk assessment 55%
  • Telephone 39%
  • Health insurance 28%
  • Telecommunication traffic 19%

• The Use of Organometallic Reaction in the Syntheses of Anticancer Agents.( I )

  Liou, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antineoplastic Agent 100%
  • Chan-Lam Coupling 96%
  • Buchwald-Hartwig Cross Coupling Reaction 79%
  • Ullmann Reaction 76%
  • Alkynylation 75%

• Bullying Experience, Attitude and Suicide Attempts among Adolescents

  Chen, P.

  8/1/12 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Bullying 100%
  • Suicide 41%
  • Taiwan 7%
  • Psychometrics 7%
  • Mental Health 5%

• 從基礎研究到臨床診斷及治療之輕度腦外傷轉譯醫學研究─臺北醫學大學/美國國家衛生研究院國際合作研究案-建立輕度腦外傷之診斷工具與治療策略(2-3)

  Chiu, W.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Investigation of Nutritional Intake and Associated Influence Factors of Patients in Different Stages of Alzheimer'S Disease

  Lin, C., Lin, Y. & Chao, J. C.

  7/1/18 → 10/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Alzheimer Disease 100%
  • Nutritional Status 63%
  • Activities of Daily Living 47%
  • Dementia 40%
  • Behavioral Symptoms 39%

• 以單點基因編輯(single base editing)作為KRAS基因突變校正之抗癌治療研究

  Lee, C.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Use of Organometallic Reaction in the Syntheses of Anticancer Agents(2/2)

  Liou, J.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Galectins-Immune Signaling Reprograming in Atrial Remodeling and Arrhythmogenesis: a Novel Therapeutic Strategy for Atrial Fibrillation

  Chen, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用幹細胞及類器官技術剖析發炎性腸道疾病及消化道癌症的病理機轉並發展治療策略(1/3)

  Lee, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Role of Pctk1 in the Progression of Colorectal Cancer and Molecular Mechanism (Continuation Project)(2/3)

  Wei, P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of the Relationship of Acid-Sensing Ion Channels and Osteoblasts

  Lee, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Acid Sensing Ion Channels 100%
  • Osteoclasts 33%
  • Osteoblasts 31%
  • Bone and Bones 14%
  • Degenerin Sodium Channels 14%

• 認知功能缺損長者的平衡控制與動作策略：三維動作分析以及穿戴式雙重任務訓練裝置之開發及其於居家介入之成效(第二、三期)(2/2)

  Kuan, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Structural Engineering of Biaryls, Alkaloids, Flavones and Coumarins to Furnish Anti-Fibrotic Agents for Idiopathic Pulmonary Fibrosis

  Nepali, K.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylase Inhibitors 100%
  • Drug Design 98%
  • Flavones 62%
  • Coumarins 59%
  • Research Personnel 59%

• 科研創業計畫：居家互動式呼吸監測與肺復原

  Tseng, C.

  7/1/22 → 6/30/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討新型雙效HSP及HDAC抑制藥物在視網膜疾病之治療作用

  Hsiao, G.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以CD3標靶微脂粒包覆免疫佐劑結合樹突狀細胞之胞外泌體應用於大腸癌免疫治療(1/3)

  Lin, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 肺阻塞表型分析與治療策略(2/3)

  Tseng, C.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology