Taipei Heart Institute (THI), Taipei Medical University

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2019 2021

• 151 Finished

Projects per year

Search results

• Finished

  探討UBE2S在 Oxaliplatin抗藥性大腸癌中的DNA修補功能與評估小分子物SMDB1在臨床上的治療

  Cheng, C.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 研究CEACAM6參與結直腸癌發生中的機制以及抗CEACAM6抗體偶合的納米粒子對轉移性結直腸癌的靶向療法和臨床前評估

  Wu, A. T.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Engineering and Optimization of Nano-enabled Targeting and Therapeutic System

  Mi, F.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Development of Smart Peptide-based Therapeutic System for Coronary Ischemia

  Cheng, T.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Preclinical efficacy evaluation and mechanistic exploration of CII-NTTS

  Wu, A. T.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 發展具有靶向及溶解血栓功能的奈米藥物治療平台(1/2)

  Mi, F.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展具化學/光熱複合療效及骨組織修復功能之奈米粒子應用於發生骨轉移之乳癌治療(1/3)

  Mi, F.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討小分子藥物在肺癌抑制 UBE2S 的癌化機轉及評估其臨床的應用

  Cheng, C.

  3/1/20 → 2/28/21

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 探討UBE2S在 Oxaliplatin抗藥性大腸癌中的DNA修補功能與評估小分子物SMDB1在臨床上的治療

  Cheng, C.

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 新聘教師研究補助

  Shih, C.

  1/1/20 → 12/31/20

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Study the Toxicity of Chitosan Nanowaste in Freshwater Fishes: Establishment of Toxicity Assessment Platform for Nanomaterials

  Cheng, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation on the Effect of Momordicine I on the Insulin-Induced Hypoxia-Inducible Factor-1α/Vascular Endothelial Growth Factor Dependent Microvascular Dysfunction in Diabetes Mellitus

  Sung, L.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Optimal Cut-Off Values for Obesity: Investigating Dxa-Based Abdominal Fat Distribution to Predict Cardiovascular Risk Factors in Taiwan

  Tay, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanistic Insight of Pcsk9 Suppression on Atrial Fibrosis with Direct Anti-Fibrotic Activity: a Novel Therapeutic Strategy for Atrial Myopathy and Arrhythmogenesis.(1/3)

  Chung, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Phosphodiesterase Isoforms Inhibitors on Atrial Arrhythmogenesis from Modulations on Fibroblasts Activity and Cardiomyocytes Electrophysiology(2/2)

  Huang, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Galectins-Immune Signaling Reprograming in Atrial Remodeling and Arrhythmogenesis: a Novel Therapeutic Strategy for Atrial Fibrillation(2/3)

  Chen, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanistic Insights into Scn5a Deficiency on Fibrogenesis: Implications in Channelopathy Induced Structure Remodeling

  Kao, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Effect of Chrna7-P38mapk Inflammatory Signaling Axis on Lipoprotein(A)-Induced Macrophage Polarization and Coronary Artery Spasm Development(1/3)

  Hung, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Fucoidan/Urokinase Assembled Magnetic Nanoparticles for the Detection of Thrombosis and Targeted Thrombolytic Therapy

  Mi, F.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Cafestol on Cardiac Hypertrophy.

  Liu, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Nutritional Ketosis on Cardiac Metabolism, Remodeling, and Arrhythmogenesis in Heart Failure: a Novel Stagey in Restoring Heart Function and Electrical Integrity

  Lin, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建構阿茲海默氏症細胞藥物篩選模式：分析小分子藥物488和電漿活化水抑制類澱粉斑塊的形成

  Cheng, C.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Reducing Rehospitalization and Mortality of Patients with Heart Failure by Using a Smart Database System and a Personalized Early Warning System

  Liu, J.

  6/1/19 → 5/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新聘教師研究補助

  Chung, C.

  4/1/19 → 3/31/20

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 探討UBE2S在神經膠質瘤的癌化機轉及評估在臨床的治療

  Cheng, C.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 血管內皮生長因子對於肺靜脈心肌組織之電生理特性及細胞內鈣恆定調控的研究

  Lin, Y.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › q - Cathay General Hospital

• 纖維芽細胞生成因子1對氧化誘導之氧化壓力、鈣平衡失調、和心律不整在肺靜脈的影響：一種新的心房顫動治療策略

  Chen, Y.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 人性化的網路平台協助醫學資訊管理與報表產出-自動化資訊擷取應用於輻射檢驗劑量管理

  Tay, S.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• Evolution Haptoglobins as Protein Drugs for Coronary Artery Diseas

  Cheng, T.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Haptoglobins 100%
  • Coronary Artery Disease 52%
  • Inflammation 27%
  • Nanoparticles 20%
  • Monocytes 19%

• Phosphodiesterase Isoforms Inhibitors on Atrial Arrhythmogenesis from Modulations on Fibroblasts Activity and Cardiomyocytes Electrophysiology

  Huang, J.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Galectins-Immune Signaling Reprograming in Atrial Remodeling and Arrhythmogenesis: a Novel Therapeutic Strategy for Atrial Fibrillation

  Chen, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pathophysiology of Macrophage Migration Inhibitory Factor on Electrical and Structural Remodelings in Heart Failure-Induced Atrial Arrhythmogenesis(3/3)

  Chen, Y.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heart Failure 100%
  • Atrial Fibrillation 95%
  • Atrial Remodeling 81%
  • Histone Deacetylases 68%
  • Pulmonary Veins 44%

• The Effects of Lipoprotein on the Endothelial-To-Mesenchymal Transition Process and Vessel Neo-Intimal Formation (Continuation of Most 106-2314-B-038-081; 2/3 & 3/3)

  Huang, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Endothelial Progenitor Cells 100%
  • Lipoproteins 44%
  • Endothelium 20%
  • Cardiac Catheters 16%
  • Observation 16%

• Environment-Sensitive Chitosan Nanomicelles for Ph-Jump Activation, Oxygen Evolution and Anticancer Drug Delivery(2/2)

  Mi, F.

  8/1/18 → 10/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hyaluronic Acid 100%
  • Chitosan 71%
  • Micelle 67%
  • Resistance 54%
  • Pluronic 49%

• Effects of Cafestol on Cardiac Hypertrophy.

  Liu, J.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 1. Cardiac Fibroblast Inhibition and Potential Treatment of Heart Failure: Histone Deacetylase Regulates the Mitochondria

  Kao, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylases 100%
  • Fibroblasts 86%
  • Calcium 53%
  • Homeostasis 34%
  • Heart Failure 34%

• Study the Toxicity of Chitosan Nanowaste in Freshwater Fishes

  Cheng, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • chitosan 100%
  • nanomaterials 86%
  • Danio rerio 53%
  • toxicity 32%
  • nanoparticles 21%

• Ionic Currents and Calcium Homeostasis in Atrial Arrhythmogenesis of Chronic Obstructive Pulmonary Disease Animal Model

  Lin, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Atrial Fibrillation 70%
  • Calcium 18%
  • difebarbamate, febarbamate, phenobarbital drug combination 13%
  • Homeostasis 9%

• To Study the Effects and Underlying Mechanisms of B Type Natriuretic Peptide in Endothelial-Mesenchymal Transition: a Study Regarding to Cardiac Allograft Vasculopathy

  Lin, F.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Brain Natriuretic Peptide 100%
  • Thrombomodulin 99%
  • Endothelial Progenitor Cells 55%
  • Allografts 52%
  • Tissue Donors 47%

• Ionic Currents and Calcium Homeostasis in Atrial Arrhythmogenesis of Chronic Obstructive Pulmonary Disease Animal Model

  Lin, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Atrial Fibrillation 70%
  • Calcium 18%
  • difebarbamate, febarbamate, phenobarbital drug combination 13%
  • Homeostasis 9%

• Cellular and Molecular Mechanisms with Epigenetic Regulation by Histone Deacetylation on Postopratetive Atrial and Pulmonary Vein Arrhythmogenesis

  Chen, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylases 100%
  • Atrial Fibrillation 85%
  • Pulmonary Veins 63%
  • Calcium 44%
  • Heart Atria 40%

• Effects of Cafestol on Cardiac Hypertrophy.

  Liu, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pathophysiology of Macrophage Migration Inhibitory Factor on Electrical and Structural Remodelings in Heart Failure-Induced Atrial Arrhythmogenesis

  Chen, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heart Failure 100%
  • Atrial Fibrillation 95%
  • Atrial Remodeling 81%
  • Histone Deacetylases 68%
  • Pulmonary Veins 44%

• Epigenetic Role of Pitx2c in Atrial Myocyte and Fibroblast: Therapeutic Implications of Atrial Fibrillation Mechanisms

  Kao, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibroblasts 100%
  • Calcium 50%
  • Histone Deacetylases 42%
  • MicroRNAs 41%
  • Electrophysiology 41%

• Identification and Characterization of Mutation Gene of Familiar Lymphedema

  Cheng, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lymphedema 100%
  • Mutation 46%
  • Genes 44%
  • Zebrafish 18%
  • Taiwan 18%

• The Effects of Lipoprotein on the Endothelial-To-Mesenchymal Transition Process of Mature Endothelial Cell and Endothelial Progenitor Cells in Vessel Neo-Intimal Formation

  Huang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • erucylphosphocholine 100%
  • HDL Lipoproteins 96%
  • oxidized low density lipoprotein 25%
  • Dyslipidemias 16%
  • Atherosclerosis 13%

• Environment-Sensitive Chitosan Nanomicelles for Ph-Jump Activation, Oxygen Evolution and Anticancer Drug Delivery

  Mi, F.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hyaluronic Acid 100%
  • Chitosan 71%
  • Micelle 67%
  • Resistance 54%
  • Pluronic 49%

• 代謝壓力透過AMP依賴性蛋白激酶對肺動脈心律不整之影響來解釋心臟衰竭誘發心房顫動的機轉

  Chen, Y.

  3/1/17 → 2/28/18

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 新聘教師研究補助

  Sung, L.

  1/1/17 → 12/31/17

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Anxiety, Depression and Coronary Spasm: a Synthesis of Epidemiological and Experimental Studies

  Hung, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Spasm 100%
  • Coronary Vessels 78%
  • Anxiety 22%
  • Coronary Artery Disease 22%
  • Depression 17%