School of Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2026

• 3 Not started
• 216 Active
• 2074 Finished

Projects per year

Search results

• b - Ministry of Science and Technology

  Characterization of Thalamocortical Dysrhythmia in Mild Traumatic Brain Injury Using Simultaneous Mri and Eeg Measurements and Pre-Clinical N-Acetylcysteine Treatment Response

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Acetylcysteine 44%
  • Post-Concussion Syndrome 17%
  • Neuroimaging 15%
  • Electroencephalography 14%
  • Atrophy 9%

• A Toxicological Assessment of Air Pollution in the Vicinity of a Petrochemical Complex

  Chuang, H. & Lee, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Particulate Matter 100%
  • Taiwan 54%
  • Toxicology 44%
  • Risk Assessment 38%
  • Methionine 19%

• To Study the Role of Multidrug Resistance Protein 4 on Induction of Aspirin Resistance in Type 2 Diabetes Mellitus

  Lu, W.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Subfamily B ATP Binding Cassette Transporter 100%
  • Aldehyde Reductase 68%
  • Aspirin 64%
  • Platelet Activation 25%
  • Blood Platelets 25%

• Construction and Application of Medical Image Database in Tmu Healthcare System( I )

  Huang, C.

  11/1/17 → 10/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Obesity and Cardiovascular Disease in Taiwan Women with Polycystic Ovary Syndrome

  Hsu, M., Liou, T., Chen, Y., Tzeng, C. & Hsu, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Polycystic Ovary Syndrome 100%
  • Obesity 13%
  • Metabolic Syndrome 13%
  • Endocrinologists 12%
  • Hirsutism 12%

• Molecular Mechanism of the Effect of Cafestol on Growth Factor-Induced Cardiomyocyte Hypertrophy

  Liu, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • cafestol 100%
  • Cardiac Myocytes 57%
  • urotensin II 55%
  • Hypertrophy 48%
  • Cardiomegaly 38%

• The Investigation of the Protective Effect of the Ethanol Extract from Brown Seaweed Laminaria Japonica on Chronic Kidney Disease and Its Molecular Mechanism

  Chen, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Seaweed 100%
  • fucoxanthin 53%
  • Chronic Renal Insufficiency 48%
  • Kidney 18%
  • PPAR alpha 16%

• Effect of HMGA2 in Chemotherapy Response of Colorectal Cancer Patients with Different APC Status (II)

  Yen, Y., Cheng, Y. & Wei, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Development and Clinical Application of a Miniature Transcranial Direct Current Stimulator in Rehabilitation Therapy

  Peng, C.

  11/1/13 → 10/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Patient rehabilitation 100%
  • Animals 34%
  • Health insurance 17%
  • Experiments 12%
  • Medicine 11%

• Development of Interactive Augmented Reality and Electrical Neuromodulation System to Improve Neuroplasticity and Limbs Function in Persons with Stroke

  Lai, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Targeting Class III Phosphoinositide 3-Kinase (Pi3k) for Anticancer Drug Discovery

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphoinositide 100%
  • 3-Methyladenine 41%
  • Antineoplastic Agent 32%
  • Protein Synthesis 25%
  • LY294002 22%

• The Role and Molecular Mechanism of PPARα in Acute Kidney Injury---Focus on the Protective Effect in Renal Tubular Cell

  Hsu, Y., Chen, T. & Chen, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Type C Phospholipases 73%
  • Kidney 56%
  • Acute Kidney Injury 37%
  • Gentamicins 27%

• Macro and Micro Biomechanical Studies of Soft Tissue Remodeling under Tissue Expansion (II)

  Chen, H.

  8/1/12 → 1/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tissues 100%
  • mechanical properties 29%
  • animal injuries 22%
  • clinical trials 21%
  • texture 16%

• The Comparison of Complications and Mortality after Surgery between General Anesthesia and Regional Anesthesia in the Elderly

  Liao, C., Cherng, Y. & Chen, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Conduction Anesthesia 100%
  • General Anesthesia 89%
  • Elderly 42%
  • Mortality 35%
  • Postoperative Complications 30%

• In Vi Vo and in Vi Tro Screening of the Dyslipidemic Antihypertensives, Studying the Mechanism to Modulate Signaling Srebp and Ppar in the Renal Cells, and Investigating the Cotherapy with Mountain Celery Seed Aqueous Extract in Reducing Worsen Renal F(3/3)

  Chen, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Apium 100%
  • Seeds 63%
  • Kidney 60%
  • Antihypertensive Agents 47%
  • Sterol Regulatory Element Binding Proteins 31%

• Modulation of Tumor Microenvironment by Nucleic Acid Chimeras as a New Paradigm for Adjuvant Cancer Therapy

  Yeh, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • neoplasms 100%
  • cytokines 66%
  • neoplasm progression 60%
  • neoplasm cells 55%
  • chimerism 45%

• A Large Series of Clinical and Imaging Investigation to Patients with Chronic Lower Limb Edema with Unclear Etiology

  Chan, W. P.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phlebography 100%
  • Edema 47%
  • Lower Extremity 36%
  • Angiography 15%
  • Leg 10%

• The Roles of Fibronectin Fragments in the Articular Chondrocytes: from Single Nucleotide Polymorphism to Functional Investigation.

  Lee, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibronectins 100%
  • chondrocytes 59%
  • cartilage 53%
  • integrins 43%
  • osteoarthritis 23%

• Effects of Propofol on Traumatic Brain Injury-Induced Insults to the Mouse Blood-Brain Barrier and Its Possible Mechanisms

  Chang, H. & Chen, R.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Propofol 90%
  • Blood-Brain Barrier 73%
  • Brain Edema 28%
  • Craniocerebral Trauma 16%

• Study the Bacteria Species of Pneumonia and Early Detect the Pathogen from Expired Gas by Electronic Nose

  Shih, C.

  5/1/11 → 4/30/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electronic Nose 100%
  • Pneumonia 35%
  • Sputum 34%
  • Air 28%
  • Medicine Chests 15%

• A Multidisciplinary Study of the Pathophysiology of Blast-Induced Mild Traumatic Brain Injury

  Chiang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of the Angiogenesis Promoting Effect of Irradiation Induced Mir-17-5p in Oral Cancer Cells

  Wu, S.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mouth Neoplasms 100%
  • Neoplasms 51%
  • Angiogenesis Inducing Agents 51%
  • Angiogenesis Inhibitors 27%
  • Cell Culture Techniques 26%

• Functional Mri Evaluation of the Cognitive Outcome in the Patients Receiving Carotid Artery Stenting

  Chen, D. C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Carotid Stenosis 100%
  • Carotid Arteries 60%
  • Stroke 30%
  • Cognitive Dysfunction 29%
  • Dementia 14%

• Microarray Investigation of Global Regulation by speG in Salmonella typhimurium, Human Intestinal Epithelium, and B Lymphocytes in an in vitro M-Cell Model

  Fang, S.

  4/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • cells 100%
  • Salmonella 86%
  • B-lymphocytes 85%
  • Salmonella Typhimurium 68%
  • transposons 39%

• Clinical Evaluation of an Oligonucleotide Array for Detection of First- and Second-Line Drug Resistance of Mycobacterium tuberculosis Complex in a Northern Taiwan Medical Center (I)

  Yu, M.

  3/1/15 → 2/29/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tuberculosis 100%
  • ofloxacin 84%
  • amikacin 81%
  • rifampicin 73%
  • kanamycin 67%

• 臺北醫學大學自有貴重儀器共用服務計畫

  Lin, S.

  12/1/17 → 12/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Relationships of One-Carbon Cycle Pathways with Psychopathology and Metabolic Abnormalities in Patients with Schizophrenia and Potential Intervention Strategy with 5-Methyltetrahydrofolate and Vitamin B12

  Chen, C., Huang, S. & Lu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Folic Acid 100%
  • Vitamin B 12 69%
  • Carbon Cycle 66%
  • Schizophrenia 51%
  • 5-methyltetrahydrofolate 48%

• Activation of Adenosine A3 Receptors Suppresses Airway Hypersensitivity

  Lin, Y. & Hwang, L.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adenosine A3 Receptor Agonists 100%
  • Adenosine A3 Receptors 80%
  • Hypersensitivity 72%
  • Unmyelinated Nerve Fibers 47%
  • Lung 37%

• Macro and Micro Biomechanical Studies of Soft Tissue Remodeling under Tissue Expansion

  Chen, H.

  8/1/11 → 11/30/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tissues 100%
  • skin (animal) 31%
  • mechanical properties 29%
  • animal injuries 22%
  • clinical trials 21%

• Relationships of One-Carbon Cycle Pathways with Psychopathology and Metabolic Abnormalities in Patients with Schizophrenia and Potential Intervention Strategy with 5-Methyltetrahydrofolate and Vitamin B12

  Chen, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Folic Acid 100%
  • Vitamin B 12 69%
  • Carbon Cycle 66%
  • Schizophrenia 51%
  • 5-methyltetrahydrofolate 48%

• Development of 3d-Printing Dynamic Orthosis-For Hemiplegic Lower Limbs( I )

  Chen, S.

  9/1/14 → 11/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • 3D printers 100%
  • Fabrication 37%
  • Costs 12%

• Power-Assisted Rehabilitation Device with Electrical Stimulation---Brige from Engineering to Clinical Trials

  Chen, S.

  9/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Biomedical equipment 100%
  • Patient rehabilitation 86%
  • Muscle 85%
  • Brain 50%
  • Biofeedback 43%

• Investigation of the cerebral perfusion changes in patients with mild traumatic brain injury using 3D bSSFP arterial spin labeling MRI

  Liu, H., Tsai, P., Chen, C. & Lu, C.

  2/1/16 → 1/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。

  Wang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • glucose-regulated proteins 100%
  • Neoplasm Metastasis 25%
  • Neoplasms 23%
  • Breast Neoplasms 16%
  • Psychological Inhibition 12%

• The Role of Endothelial-To-Mesenchymal Transition in Arteriovenous Fistula Neointimal Hyperplasia

  Sue, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Decellularized Plant Extracellular Matrices as a Scaffold for Tissue Engineering(2/2)

  Tseng, H.

  8/1/18 → 8/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • extracellular matrix 100%
  • animal tissues 65%
  • tissue engineering 44%
  • porometers 29%
  • polyglutamic acid 28%

• Pulmonary Effects of Chorioamnionitis and Postnatal Hyperoxia in Rat Offspring

  Chen, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chorioamnionitis 100%
  • Hyperoxia 72%
  • Bronchopulmonary Dysplasia 58%
  • Renin-Angiotensin System 48%
  • Lung Injury 37%

• Investigation on Developing Novel Biomarkers and Treatments in the Patients with Fibromyalgia

  Kang, J.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Transcranial Direct Current Stimulation 38%
  • Exercise 32%
  • Virtual Reality 30%
  • Biomarkers 12%

• The Integrated Theraptic Effect of the Major Components of Psidium guajava L. Aqueous Extracts (PE) (Gallic Acid, Quercetin, EGCG, and Rutin) Combining with Medical Trials and Control Diets on the Chronic Kidney Disease

  Chen, K. & Peng, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Gallic Acid 66%
  • Psidium 32%
  • Diet 27%
  • Rutin 26%

• Psychophysiological Effects of Lactobacillus Plantarum Ps128 in Patients with Major Depressive Disorder: an 8-Week Randomized, Double-Blind, Placebo-Controlled Trial

  Chen, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Study on Trans-Neuronal Striato-Nigral Degeneration-Induced Movement Disorders after Stroke: Evaluation with Grey Matter Suppression Ir and Diffusion Tensor Imaging( I )

  Chen, C.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Movement Disorders 100%
  • Stroke 53%
  • Diffusion Tensor Imaging 50%
  • Middle Cerebral Artery 48%
  • Gray Matter 45%

• The Alteration of Inflammatory Reflex and Its Association with Psychotropic Drugs in Bipolar Disorder from Acute Mania to Full Remission(2/2)

  Tsai, S.

  8/1/16 → 10/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Bipolar Disorder 100%
  • Reflex 82%
  • Cholinergic Agents 32%
  • Psychological Power 21%
  • Antipsychotic Agents 21%

• Molecular Mechanism in Amyloid Peptide-Induced Cerebral Endothelial Cell Apoptosis:Role of Hdac and Ampk

  Hsu, M.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Acetylation 100%
  • Histone Deacetylases 95%
  • Endothelial Cells 60%
  • Cerebral Amyloid Angiopathy 57%
  • Sirtuins 55%

• Effect of pacemaker current inhibitor (Ivabradine) on sinoatrial node function and pulmonary vein arrhythmogenesis

  Lin, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pulmonary Veins 100%
  • Ivabradine 66%
  • Atrial Fibrillation 48%
  • Sinoatrial Node 40%
  • Cardiac Arrhythmias 27%

• Anti-Tumor Mechanisms of the Novel Series of Aliphatic Hydroxamate Derivatives, Wmj-J Compounds

  Hsu, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • WMJ-S-001 100%
  • Neoplasms 73%
  • Colorectal Neoplasms 66%
  • Acetylation 65%
  • HCT116 Cells 53%

• Exploring the Potential Impacts of Early-Life Sleep Deprivation on Tooth Development and Dental Structure: Translational Study with Spectroscopy, Computed Tomography, Ultrastructural Morphology and Cell Biology

  Chang, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Analyze Exhaled Gas of COPD Patients( I )

  Shih, C.

  5/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Gases 47%
  • Electronic Nose 30%
  • Volatile Organic Compounds 27%
  • Therapeutic Irrigation 21%

• Role of Activating Transcription Factor 3 in the Protective Effect of Resveratrol in Cardiomyocytes

  Liu, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Resveratrol 100%
  • Activating Transcription Factor 3 81%
  • Doxorubicin 63%
  • Cardiac Myocytes 47%
  • Activating Transcription Factors 25%

• Dissected the Role of Glucose-Regulated Protein 94 (GRP94),The Clinically Therapeutic Implication and Drug Development in Colon Cancer

  Wei, P. & Chang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • glucose-regulated proteins 100%
  • Colonic Neoplasms 43%
  • Colorectal Neoplasms 38%
  • Neoplasms 23%
  • Neoplasm Metastasis 19%

• Studies on the Role of ORMDL3 in Thrombin-Induced IL-8/CXCL8 Expression and Airway Inflammation

  Chen, B.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Orosomucoid 100%
  • Thrombin 74%
  • Interleukin-8 34%
  • Transcription Factor AP-1 26%
  • Asthma 23%