School of Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 3 Not started
• 202 Active
• 2322 Finished

Projects per year

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• b - Ministry of Science and Technology

  真實世界數據應用於風險評估設定醫療照護模式以提昇住院照護品質研究-方法建立與導入實施(1/2)

  Chen, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發血吸蟲蟲卵抗原中標的抗原蛋白作為抑制肺部發炎藥物及成分分析與機制研究

  Cheng, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Functional Investigation of Heat Shock Protein in Esophageal Squamous Cell Cancer with Implications in Prognostic Prediction and Therapeutic Targeting

  Tzao, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heat-Shock Proteins 100%
  • Esophageal Squamous Cell Carcinoma 56%
  • Neoplasms 33%
  • 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin 28%
  • Esophageal Neoplasms 24%

• Mri Study on Trans-Neuronal Degeneration of the Thalamic Networks after Ischemic Stroke

  Chen, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thalamus 100%
  • Stroke 96%
  • Thalamic Nuclei 52%
  • Cerebral Infarction 43%
  • Gait 38%

• Glutamine Modulates Hepatic Akt/Mtorc2/Foxo1 Pathway in Mice with Polymicrobial Sepsis.

  Pai, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glutamine 100%
  • Mechanistic Target of Rapamycin Complex 2 73%
  • Sepsis 53%
  • Phosphatidylinositol 3-Kinases 28%
  • Kupffer Cells 26%

• 抑制NLRP3發炎體- 糖尿病心肌病變的治療新策略

  Lee, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Study on Trans-Neuronal Striato-Nigral Degeneration-Induced Movement Disorders after Stroke---Evaluation with Grey Matter Suppression Ir and Diffusion Tensor Imaging (III)

  Chen, C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects of the Apoe4 Allele on Cerebral Structural and Functional Connectivity- a Diffusion Tensor Imaging and Resting-State Mri Study

  Chen, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Apolipoprotein E4 100%
  • Alleles 78%
  • Brain 39%
  • Short-Term Memory 31%
  • Magnetic Resonance Imaging 26%

• Detrimental Effects of an Aryl-Hydrocarbon Receptor Agonist, 3mc, on Brain Vascular Integrity and Permeability, and the Therapeutic Intervention by Statin Derivatives.

  Juan, S. & Hwang, L.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Aryl Hydrocarbon Receptors 100%
  • Retinoblastoma Protein 56%
  • extracellular matrix receptor 50%
  • Extracellular Matrix Proteins 49%
  • Phosphatidylinositol 3-Kinases 33%

• Molecular Mechanisms of Propofol-Involved Protection against Ischemia Brain Injuries 全文電子檔： 全文連結1

  Chen, T.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Propofol 100%
  • Ischemia 76%
  • Brain Injuries 75%
  • Reperfusion 34%
  • Mitogen-Activated Protein Kinases 30%

• Circuits of IGF-1R and Niche Signaling (Hypoxia/Inflammation) in Stem Cell Transformation and Its Clinical Implication of Molecular Target Therapy (Model of Germline Stem Cells)

  Huang, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplastic Stem Cells 100%
  • Stem Cells 86%
  • Hypoxia 55%
  • Inflammation 34%
  • Seminoma 29%

• Amyloid and Neuroinflammation in Vascular Dementia Animal Model

  Hu, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Amyloid 100%
  • Cognitive Dysfunction 86%
  • Blood Vessels 62%
  • Alzheimer Disease 51%
  • Stroke 45%

• The Potential Role of Glycogen Synthase Kinase-3 in Dengue Virus-Infected Mononuclear Phagocytes

  Lin, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycogen Synthase Kinase 3 100%
  • Dengue Virus 93%
  • Virus Diseases 47%
  • Interleukin-10 35%
  • Cellular Immunity 28%

• Molecular Insights into Ketogenic Diet on Cardiac Metabolic Disorders in Diabetic Cardiomyopathy

  Lee, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 膠淋巴系統於混合型失智症之角色(2/2)

  Hu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related HCC under Hypoxia and Its Clinical Implication

  Huang, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Interleukin-6 100%
  • Hepatocellular Carcinoma 94%
  • Hypoxia 55%
  • Drug Resistance 32%
  • Neoplasms 30%

• Novel Roles of Aryl-Hydrocarbon Receptor ((AhR) on Epigenetic and Post-Translational Modification of Cell-Cycle Regulatory Genes and Enos in Vascular Endothelial Cells---The Therapeutic Potential of Resveratrol/Statins

  Juan, S. & Hwang, L.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Aryl Hydrocarbon Receptors 100%
  • Phosphatidylinositol 3-Kinases 25%
  • cdc Genes 24%
  • Epigenomics 22%
  • Umbilical Cord 22%

• Biodegradable Multi-Agents Incorporated Nanoparticles Supported Chemoprotective Gene Therapy Enhances Chemotherapy Tolerance and Efficacy in Malignant Glioma Rats

  Tseng, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Carcinogenic Mechanisms of Histamine N-Methyltransferase-Mediated Breast Cancer Formation

  Wu, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Breast Neoplasms 19%
  • Neoplasms 7%
  • Carcinogenesis 6%

• 探討臨床級胎盤間質幹細胞分泌體於促進半月板前驅細胞之再生能力與免疫調控之研究

  Huang, Y.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 肝醣合成酉每激酉每3於登革病毒感染單核吞噬細胞的潛在角色(2/3)

  Lin, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Clinical Evaluation of an Oligonucleotide Array for Detection of First- and Second-Line Drug Resistance of Mycobacterium tuberculosis Complex in a Northern Taiwan Medical Center (I)

  Yu, M.

  3/1/15 → 2/29/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • tuberculosis 100%
  • ofloxacin 84%
  • amikacin 81%
  • rifampicin 73%
  • kanamycin 67%

• Indoxyl Sulfate, Chronic Kidney Disease and Heat Shock Protein Modulate the Atrial Electrophysiological Characteristics

  Hsieh, M.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Atrial Fibrillation 89%
  • Indican 89%
  • Pulmonary Veins 48%
  • Heat-Shock Proteins 43%

• Service for Sharing Precious Instruments of Taipei Medical University

  Lin, C.

  1/1/12 → 12/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the carcinogenic mechanisms of histamine N-methyltransferase-mediated breast cancer formation

  Wu, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Breast Neoplasms 19%
  • Neoplasms 7%
  • Carcinogenesis 6%

• Effect of Sumoylation on Gsk-3beta-Mediated Autophagy

  Shih, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycogen Synthase Kinase 3 100%
  • Autophagy 79%
  • Cadmium 41%
  • Sumoylation 38%
  • Small Interfering RNA 19%

• Effect of Sumoylation on Gsk-3beta-Mediated Autophagy

  Shih, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycogen Synthase Kinase 3 100%
  • Autophagy 79%
  • Cadmium 41%
  • Sumoylation 38%
  • Small Interfering RNA 19%

• Regulatory Mechanisms of Mitochondria Involved in Apoptosis, Necrosis and Autophagy in Anuclear Cells, Platelets

  Sheu, J.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Blood Platelets 100%
  • Mitochondrial Transmembrane Permeability-Driven Necrosis 53%
  • Mitochondria 40%
  • Cyclophilin D 39%
  • Apoptosis 35%

• Gene Polymorphism of Fatty Acids Metabolism Enzymes in Elderly Patients with Depression and Mild Cognitive Impairment

  Huang, S. & Lee, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cognitive Dysfunction 100%
  • Elderly 82%
  • Depression 79%
  • Apolipoprotein E2 61%
  • Fatty Acids 52%

• Service for Sharing Precious Instruments of Taipei Medical University

  Lin, C.

  1/1/13 → 1/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Novel Roles of Aldose Reductase (AR) in Collagen GPVI- and Thrombin PAR4-Mediated Platelet Activation and Apoptosis---Regulatory Machinery of Arf-AR Signaling in Anucleate Cells

  Sheu, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Aldehyde Reductase 100%
  • Platelet Activation 32%
  • Blood Platelets 28%
  • convulxin 26%
  • epalrestat 21%

• Chemical Modification to the Surface of Mesoporous Silica Nanoparticles Effects on the Blood-Brain-Barrier Permeability, Nano-Hazard, and Immune-Enhance

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Nanoparticle 100%
  • Permeability 49%
  • Protein 38%
  • Confocal Microscopy 35%
  • Neutralization 31%

• Environment-Sensitive Chitosan Nanomicelles for Ph-Jump Activation, Oxygen Evolution and Anticancer Drug Delivery

  Mi, F.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hyaluronic Acid 100%
  • Chitosan 71%
  • Micelle 67%
  • Resistance 54%
  • Pluronic 49%

• Molecular Mechanisms of Anti-Inflammatory Effects of Intravenous Anesthetic Agent Ketamine on Lipopolysaccharide-Activated Macrophages

  Chen, T. & Chen, R.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • ketamine 100%
  • lipopolysaccharides 80%
  • macrophages 39%
  • Toll-like receptors 32%
  • cytokines 32%

• Preclinical Assessment of Cadherin11 Antagonists for Treating Drug-Resistant Breast Cancer through Modulating Tumor Immunity and Suppression of Cancer Stem Cells

  Chao, T.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • osteoblast cadherin 100%
  • Breast Neoplasms 37%
  • Neoplastic Stem Cells 31%
  • Neoplasm Metastasis 12%
  • Breast 7%

• Study of Expression and Functional Mechanisms of Histamine N-Methyltransferase (HNMT) in Tumorigenesis and Correlation with Progression in Lung Cancer

  Wang, L., Lee, W., Ho, Y. & Wu, A. T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Lung Neoplasms 43%
  • Carcinogenesis 18%
  • Neoplasms 10%
  • Genes 9%

• The Role of Inflammatory Gene Polymorphisms on Risk of Post-Stroke Vascular Dementia (I)

  Chiou, H., Chi, N., Lin, H., Wu, C., Hsieh, F., Hu, C. & Hsieh, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 93%
  • Cognitive Dysfunction 89%
  • Blood Vessels 52%
  • Inflammation 36%
  • Whole Exome Sequencing 16%

• The Machnism of Calcium Containing Cystals in Bone Remodeling

  Chang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • bones 100%
  • osteoclasts 77%
  • arthritis 67%
  • osteoblasts 43%
  • calcium 31%

• Translational Investigation for Tea Attenuate Smoking-Induced Disease---Breast Cancer and Atherosclerosis as a Mechanistic Study

  Ho, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tea 100%
  • Nicotine 26%
  • Capsules 23%
  • Breast Neoplasms 23%
  • Smoking 19%

• 纖維肌痛症患者之微生物叢相-腸-腦軸線異常與神經發炎的研究

  Kang, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Effects of Metabolic Abnormalities on Cognitive Function in Schizophrenic Patients

  Lu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Metabolic Syndrome 100%
  • Schizophrenia 78%
  • Cognitive Dysfunction 49%
  • Cognition 38%
  • Executive Function 12%

• The Measure of Palliative Care Spiritual Care Competency and the Effectiveness of an Educational Program for Palliative Spiritual Care Providers

  Chiou, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Palliative Care 100%
  • Program Evaluation 46%
  • Education 32%
  • Research Design 24%
  • Learning 15%

• Wearable Medical Modnles with Far Infrared Light and Microwave Pules Measurement (Emphasis Theme:A3)( I )

  Chen, C.

  5/1/17 → 4/30/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Huang, Y., Shen, S., Yang, W., Li, Y., Yeh, C. & Kao, S.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • endometrium 100%
  • microRNA 90%
  • stem cells 61%
  • cell adhesion molecules 54%
  • metastasis 35%

• The Study of the Protective Effect of Far-Infrared-Improved Mitochondrial Function on Pancreatic Β-Cells in Diabetes Mice and Its Sirt1- and Plzf-Associated Mechanisms

  Chen, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• HMGA2, a New Target of Thyroid Hormone-Induced Progression in Colorectal Cancers

  Lin, H., Chang, T. & Yen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • AT-Hook Motifs 100%
  • Thyroid Hormones 75%
  • tetraiodothyroacetic acid 70%
  • Colorectal Neoplasms 43%
  • Catenins 31%

• Mechanisms and Clinical Applications of Transcranial Direct Current Stimulation in Treating Patients with Firbomyalgia

  Kang, J., Chen, S. & Lee, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Transcranial Direct Current Stimulation 57%
  • Serotonin and Noradrenaline Reuptake Inhibitors 11%
  • Hyperalgesia 8%
  • Hydrotherapy 6%

• Development of 3d-Printing Dynamic Orthosis-For Hemiplegic Lower Limbs( III )

  Chen, S.

  9/1/16 → 12/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Activating Transcription Factor 3 on Endoplasmic Reticulum Stress, Oxidative Stress, Visceral Fat Metabolism, and Inflammation in Fructose-Fed Hypertensive Mice

  Fang, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Activating Transcription Factor 3 100%
  • Fructose 55%
  • Intra-Abdominal Fat 43%
  • Endoplasmic Reticulum Stress 27%
  • Oxidative Stress 21%

• Study of the Molecular Mechanisms of Hdac Inhibitors on the Regulation of Calcium Pyrophosphate Crystals Formation

  Chang, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology