School of Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2026

• 3 Not started
• 222 Active
• 2064 Finished

Projects per year

Search results

• CD44和RhoA蛋白在腎細胞癌之角色並鑑別miRNAs對CD44的誘導作用之影響

  Juan, S.

  6/1/14 → 5/31/16

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 以表面增強拉曼光譜檢測關節炎微量晶體

  Liu, Y.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 第二型糖尿病人與高血壓合併腎衰竭病人之脂蛋白對血管內皮前驅細胞功能之影響。

  Huang, C.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 比較機械手臂輔助、腹腔鏡輔助或傳統開腹手術於婦科癌症治療之研究

  Liu, W.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 台灣長期接受血液透析之心臟衰竭病人使用β受體阻斷劑之治療效果與存活率分析

  Sue, Y.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 長期空氣污染物暴露與慢性阻塞性肺疾病病患骨質疏鬆症之相關性研究

  Chuang, K.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• Casein kinas 2/MSK1依賴NF-kB活化媒介thrombin誘導肺部上皮細胞IL-8/CXCL8表現之探討

  Chen, B.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 卵巢癌幹細胞之代謝研究-I

  Lai, H.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 探討胞外基質Laminin與類胰島素生長因子-1於精原幹細胞自我更新之訊息傳遞機制

  Huang, Y.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 糖尿病腎病變惡化之全基因組關聯研究

  Wu, M.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 評估小分子團水應用於幼年期睡眠剝奪傷害下護肝功能之潛在成效

  Chang, H.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 免疫蛋白?體在慢性呼吸道疾病之研究:探討免疫反應與發炎反應之交互作用

  Feng, P.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 建立癌症新診斷病人健康素養評量工具與評估計畫(103-104年)

  Bai, C. & Yang, K.

  6/4/14 → 6/3/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

• The Effect of Long Acting GnRH Agonist Treatment on Mitochondrial Function in

  Tzeng, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • hormone agonists 100%
  • mitochondria 91%
  • pathophysiology 42%
  • granulosa cells 38%
  • agonists 32%

• An Investigation of the Effects of Tea Component on the Inhibition of Leukocyte Nicotinic Acetylcholine Receptor Expression on Breast Cancer Patients

  Tu, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Leukocytes 100%
  • Tea 92%
  • Breast Neoplasms 87%
  • Nicotine 31%
  • Capsules 28%

• Evaluation of the Mechanism of Post-Traumatic Immunosuppression---The Role of TLR4 Trafficking and microRNA

  Lin, J. A.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • immunosuppression 100%
  • bones 72%
  • monocytes 53%
  • inflammation 46%
  • orthopedics 45%

• To Predict the Recurrence of Major Depressive Disorder Within an Integrated Bio-Psycho-Social Framework---A Follow-up Study

  Lee, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Major Depressive Disorder 100%
  • Recurrence 41%
  • Humanities 18%
  • Phototherapy 14%
  • Clinical Medicine 14%

• Functional Investigation of Heat Shock Protein in Esophageal Squamous Cell Cancer with Implications in Prognostic Prediction and Therapeutic Targeting

  Tzao, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heat-Shock Proteins 100%
  • Esophageal Squamous Cell Carcinoma 56%
  • Neoplasms 33%
  • 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin 28%
  • Hypoxia 25%

• Effect of Vasopressin Receptor Agonist and Antagonist on Pulmonary Vein and Atrial Arrhythmogenesis

  Huang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heart Atria 100%
  • Antidiuretic Hormone Receptor Antagonists 94%
  • Pulmonary Veins 76%
  • Heart Failure 48%
  • Sinoatrial Node 41%

• The Neurotrophic/Neuroprotective Role of GIP in Cellular and Rodent Models of Mild Traumatic Brain Injury (III)

  Lin, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Ultrafine Particles on Cardiopulmonary System: a Population-Based Approach

  Chuang, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Particulate Matter 100%
  • Air Pollution 68%
  • Taiwan 34%
  • United States Environmental Protection Agency 33%
  • Organized Financing 13%

• Relationship between Lumbar Vertebral Perfusion and Fat Marrow Content in Normal Subjects, Osteoporosis and Bone Metastases Using DCE-MRI and Fat-Water Separation

  Chan, W. P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Perfusion 100%
  • Bone Marrow 87%
  • Fats 39%
  • Osteoporosis 35%
  • Neoplasm Metastasis 32%

• Study on the Mechanism of Cross-Talk between Ahr and Autophagy, and Autophagy---Associated Physiological or Pathological Phenomenon on Vascular and Airway Systems (I)

  Li, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Aryl Hydrocarbon Receptors 100%
  • Autophagy 88%
  • Benzo(a)pyrene 17%
  • Fibrosis 15%
  • Endothelial Cells 15%

• 乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。

  Wang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • glucose-regulated proteins 100%
  • Neoplasm Metastasis 25%
  • Neoplasms 23%
  • Breast Neoplasms 16%
  • Psychological Inhibition 12%

• Investigation on Developing Novel Biomarkers and Treatments in the Patients with Fibromyalgia

  Kang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Transcranial Direct Current Stimulation 38%
  • Exercise 32%
  • Virtual Reality 30%
  • Biomarkers 12%

• The Effects of the APOE4 Allele on Cerebral Structural and Functional Connectivity---A Diffusion Tensor Imaging and Resting-State MRI Study

  Chen, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Alleles 100%
  • Apolipoproteins E 93%
  • Brain 47%
  • Short-Term Memory 37%
  • Magnetic Resonance Imaging 31%

• A Study on Trans-Neuronal Striato-Nigral Degeneration-Induced Movement Disorders after Stroke---Evaluation with Grey Matter Suppression Ir and Diffusion Tensor Imaging (III)

  Chen, C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Influence of Porphyromonas gingivalis Groel in Vascular Cells

  Lin, F.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Porphyromonas gingivalis 100%
  • blood vessels 46%
  • myocytes 40%
  • smooth muscle 39%
  • atherosclerosis 36%

• 探討不同選擇作用之組織蛋白去乙醯?調節成分抑制神經發炎之機制及其對腦內出血與腦炎之治療特性評估(2/3)

  Hsiao, G.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role and Molecular Mechanism of PPARα in Acute Kidney Injury---Focus on the Protective Effect in Renal Tubular Cell

  Hsu, Y., Chen, T. & Chen, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Type C Phospholipases 73%
  • Kidney 56%
  • Acute Kidney Injury 37%
  • Gentamicins 27%

• The Novel Roles of Aldose Reductase (AR) in Collagen GPVI- and Thrombin PAR4-Mediated Platelet Activation and Apoptosis---Regulatory Machinery of Arf-AR Signaling in Anucleate Cells

  Sheu, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Aldehyde Reductase 100%
  • Platelet Activation 32%
  • Blood Platelets 28%
  • convulxin 26%
  • epalrestat 21%

• The Effects of Metabolic Abnormalities on Cognitive Function in Schizophrenic Patients

  Lu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Metabolic Syndrome 100%
  • Schizophrenia 78%
  • Cognitive Dysfunction 49%
  • Cognition 38%
  • Executive Function 12%

• Developing Human Intestinal in vitro Organ Culture and an in vitro M-Cell Model as Platforms for Investigation of Novel Oral Vaccines

  Fang, S.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Organ Culture Techniques 100%
  • Vaccines 84%
  • In Vitro Techniques 74%
  • Salmonella typhimurium 48%
  • Rotavirus Vaccines 39%

• 肝醣合成酉每激酉每3於登革病毒感染單核吞噬細胞的潛在角色(2/3)

  Lin, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Association Study of Persistent Metabolic Syndrome, Inflammatory Markers, Adipose Markers and Mild Cognitive Decline

  Bai, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cognitive Dysfunction 100%
  • Metabolic Syndrome 67%
  • Mental Status and Dementia Tests 50%
  • Thromboplastin 27%
  • Waist Circumference 24%

• Dissected the Role of Glucosed-Regulated Portein 78 in the Progression, Metastasis and Therapy of Colorectal Cancer

  Wei, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • colorectal neoplasms 100%
  • metastasis 69%
  • neoplasms 55%
  • endoplasmic reticulum 32%
  • death 27%

• Mechanisms Underlying Airway Hypersensitivity Induced by Hydrogen Sulfide

  Lin, Y.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Unmyelinated Nerve Fibers 100%
  • Lung 65%
  • Hypersensitivity 50%
  • Reflex 39%
  • Ankyrins 37%

• Arsenic Methylation Capacity, Methylenetetrahydrofolate Reductase and Dna Methylation Gene Polymorphisms, Plasma Selenium Concentration and Selenoprotein Gene Polymorphisms and Renal Cell Carcinoma

  Hsueh, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Arsenic 100%
  • Renal Cell Carcinoma 80%
  • Methylenetetrahydrofolate Reductase (NADPH2) 50%
  • Methylation 45%
  • Selenoproteins 39%

• Highly Reliable Surface-Enhanced Raman Scattering Sensors

  Liu, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Raman spectra 100%
  • augmentation 22%
  • noble metals 18%
  • preparation 17%
  • sensors 17%

• Efficacy Studies of Tn-Directed Therapeutic Antibody and Immunotoxin in Syngeneic Mouse Tumor Models

  Hwang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • antibodies 100%
  • mice 94%
  • prostatic neoplasms 51%
  • neoplasms 48%
  • vaccines 21%

• Unraveling the Impact of Deletion of Androgen Receptor on Brain Trauma

  Yang, L.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Androgen Receptors 63%
  • collapsin response mediator protein-2 45%
  • Phosphorylation 18%
  • Organized Financing 12%

• 探討芳香烴受體(AhR)改變血管內皮細胞功能之新角色：經由表觀基因或後轉譯修飾(細胞週期蛋白/內皮細胞一氧化氮合成酉每)的調控與白蘆黎醇/史達汀臨床治療及應用(2/3)

  Juan, S.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Determined the Role and the Mechanims of GRP94 in Mediating the Progression and Therapeutic Responses of HCC

  Huang, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • glucose-regulated proteins 100%
  • Heat-Shock Proteins 15%
  • Neoplasms 11%
  • Neoplasm Metastasis 8%
  • Preclinical Drug Evaluations 8%

• Investigation of Glioblastoma Cell-Secreted microRNA Signatures and Their Functional Effects on Tumor Angiogenesis

  Chen, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Circulating MicroRNA 100%
  • Glioblastoma 91%
  • MicroRNAs 54%
  • Temozolomide 35%
  • Glioma 26%

• Analysis the Role of Satellite Cell during Denervation Induced Muscular Atrophy and a Trail of Transplantation of Adipocyte Derived Myogenic Stem Cells

  Chang, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • atrophy 100%
  • myogenic regulatory factors 41%
  • stem cells 38%
  • muscular atrophy 37%
  • adipocytes 27%

• Evaluation of Clinical Feasibility of Quantitative MR Perfusion Imaging and Its Calibration

  Tseng, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Magnetic Resonance Imaging 100%
  • Calibration 93%
  • Cerebrovascular Circulation 87%
  • Gray Matter 45%
  • Perfusion 45%

• Development of Vector-Borne Disease Forecasting Models Using Satellite Remote Sensing Techniques

  Chuang, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Remote sensing 100%
  • Land use 87%
  • Satellites 74%
  • Alarm systems 54%
  • Land surface temperature 46%

• 腫瘤相關巨噬細胞在誘發產生表皮生長因子受器酪胺酸酉每抑制劑的抗藥性的角色

  Feng, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Correlation between Serum Markers of Oxidative Stress, Inflammation, and Endocrine-Disrupting Chemicals (Edcs) and Their Impact on the Menstrual Cycle and Reproductive Hormone in Taiwanese Women.

  Hsu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • oxidative stress 100%
  • woman 46%
  • chemical 27%
  • hormone 25%
  • reactive oxygen species 22%

• 組蛋白去甲基酉每JARID1B基因在肺腺癌之腫瘤形成與影響腫瘤生物行為機轉之探討(1/2)

  Kuo, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology