Projects per year
- 600 - 650 out of 2,305 results
Search results
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Effect of Vasopressin Receptor Agonist and Antagonist on Pulmonary Vein and Atrial Arrhythmogenesis
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Relationships of One-Carbon Cycle Pathways with Psychopathology and Metabolic Abnormalities in Patients with Schizophrenia and Potential Intervention Strategy with 5-Methyltetrahydrofolate and Vitamin B12
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Pragmatic Challenges to Contemporary Vi Sions on Professionalism in Taiwan and Western Countries：Proposing and Evaluating a Situational and Relational Learning Paradigm Based upon Community Mental Health
Tsai, D.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects of Central Neuromodulation with Functional Electrical Stimulation on Bladder Functions in Traumatic Brain Injured Rats
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Determined the Role and the Mechanims of GRP94 in Mediating the Progression and Therapeutic Responses of HCC
Huang, M.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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氧化還原作用調控蛋白質去磷酸酉每羰基化和去羰基化反應對動脈血管內膜增生之影響(1/2)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Study the Function and Regulation of miRNAs in Pancreatic Cancer Progression (I)
Huang, M.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Evaluation of Clinical Feasibility of Quantitative MR Perfusion Imaging and Its Calibration
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Neurotrophic/Neuroprotective Role of GIP in Cellular and Rodent Models of Mild Traumatic Brain Injury (III)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects of Uteroplacental Insufficiency and Hyperoxia on Lung Development and Epigenetic Alterations in the Rat Offspring
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Serum Free Cultivation of Multi-Layered Oral Mucosa Epithelial Cell Sheet for Autologous Corneal Epithelium Repairing and Its Animal Model
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Role of HBX and IL-6 in Regulating SENP1/Stemness Properties of HBV-Related HCC under Hypoxia and Its Clinical Implication
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Investigation of Glioblastoma Cell-Secreted microRNA Signatures and Their Functional Effects on Tumor Angiogenesis
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Studies of Anti-Cancer Activity of Folic Acid
Lee, W.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Establish the Research Platform for Studying Triple-Negative Breast Tumor Microenvironment Regulation: the Hyaluronan Synthase-3 Mediated Antitumor Effects as an Example.
Ho, Y. & Wu, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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CXCL5/CXCR2/JNK Axis Is the Shared Pathway of Neuroinflammation and Microvascular Damage That Contributes to White Matter Injury in the Immature Brain
Huang, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Development of a Computerized Adaptive Testing of the Health Literacy in Stroke Rehabilitation
Hou, W.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Efficacy Studies of Tn-Directed Therapeutic Antibody and Immunotoxin in Syngeneic Mouse Tumor Models
Hwang, J.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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探討不同選擇作用之組織蛋白去乙醯?調節成分抑制神經發炎之機制及其對腦內出血與腦炎之治療特性評估(2/3)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Highly Reliable Surface-Enhanced Raman Scattering Sensors
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Short-Chain Fatty Acids Act as Anti-Allergic Regulators on Immune Effector Cells and Exert Immune-Modulatory Effects on Ovalbumin-Induced Allergic Diseases in Mice
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Effect of Muscle Strength Training on Body Composition and Sarcopenic Obesity among the Female Overweight Elderly
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Biomarkers Associated with Toll-Like Receptors and Neuroimage Study in Ischemic Stroke Patients (II)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Therapeutic Strategies for Traumatic Brain Injury with Novelly Desinged Drugs (III)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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粒狀空氣污染物所產生的氧化壓力對慢性阻塞性肺疾病患者的泛素-蛋白酉每平衡系統之影響:探討氧化壓力，異常發炎以及蛋白質氧化之關係
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Explore the Molecular Mechanisms and Application of microRNA-16 in In Acute Kidney Injury
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Evaluation of the Mechanism of Post-Traumatic Immunosuppression---The Role of TLR4 Trafficking and microRNA
Lin, J. A.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Development of Vector-Borne Disease Forecasting Models Using Satellite Remote Sensing Techniques
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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探討NLRP12調控病毒引起免疫反應之機轉(1/3)
Chen, S.
8/1/15 → 8/1/15
Project: A - Government Institution › b - Ministry of Science and Technology
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人類 ZFP36L1與ZFP36L2蛋白質在抗病毒機制之研究(1/2)
Lin, R.
8/1/15 → 8/5/15
Project: A - Government Institution › b - Ministry of Science and Technology
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TGF-beta誘導人類大腸癌細胞CTGF表現之機轉研究
6/1/14 → 8/31/15
Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital
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Chitosan Nanoparticle as a Macrophage-Targeting Drug Delivery Carrier
8/1/14 → 8/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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北區高階生醫產業聚落及產業規劃-台灣遠距健康產業聚落發展先導計畫
9/1/14 → 8/31/15
Project: A - Government Institution › c - Ministry of Health and Welfare
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TMU103-AE1-B03
10/1/14 → 9/30/15
Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty
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Study of glycosyl hydrolase and carbohydrate interaction by silicon nanowire effect
1/1/14 → 9/30/15
Project: C - Project of Alliance › j - National Taipei University of Technology
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Differential Machinery of Pluripotency Regulation in Stem Cells in Embryonic Stage and Somatic Cancers and Its Clinical Implications in Human Diseases---Crosstalk among Niche Growth Factor/Cytokine Signaling, Extracellular Matrix, and Epigenetic Netw (I)
10/1/14 → 9/30/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Mechanisms Underlying Airway Hypersensitivity Induced by Hydrogen Sulfide
8/1/14 → 10/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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TMU103-AE1-B08
11/1/14 → 10/31/15
Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty
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TMU103-AE1-B05
11/1/14 → 10/31/15
Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty
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A Study on Trans-Neuronal Striato-Nigral Degeneration-Induced Movement Disorders after Stroke---Evaluation with Grey Matter Suppression Ir and Diffusion Tensor Imaging (III)
8/1/14 → 10/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Analyze Exhaled Gas of COPD Patients( I )
5/1/14 → 10/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Developing Human Intestinal in vitro Organ Culture and an in vitro M-Cell Model as Platforms for Investigation of Novel Oral Vaccines
8/1/14 → 10/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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經表皮塗抹硝酸甘油軟膏於痔瘡切除術後之止痛作用
3/1/14 → 10/31/15
Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital
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Down-Regulation of RanGAP Augments Nucleus BCR-ABL Level to Potentiate the Drug Efficacy of Imatinib in Chronic Myelogenous Leukemia
8/1/14 → 10/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Optimization of Human Meniscus Imaging and Its Clinical Application for Osteoarthritis (II)
Tsai, P.
8/1/14 → 10/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Development of 3d-Printing Dynamic Orthosis-For Hemiplegic Lower Limbs( I )
9/1/14 → 11/30/15
Project: A - Government Institution › b - Ministry of Science and Technology
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奈米金屬微粒對勞工健康效應指標影響評估
6/12/15 → 11/30/15
Project: A - Government Institution › f - Other (Funded by Government)
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Evaluation on prevention for metabolic syndrome and diabetes mellitus through lifestyle modification intervention in pre-diabetic subjects (100-104)
Chiou, H., Bai, C., Tang, C., Yang, S., Su, C., Liou, T., Wang, S., Chen, J., Hsieh, A. & Huang, C.
12/24/14 → 12/5/15
Project: A - Government Institution › c - Ministry of Health and Welfare