School of Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2026

• 2 Not started
• 185 Active
• 2304 Finished

Projects per year

Search results

• Mechanisms and Clinical Applications of Transcranial Direct Current Stimulation in Treating Patients with Firbomyalgia

  Kang, J., Chen, S. & Lee, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Transcranial Direct Current Stimulation 57%
  • Serotonin and Noradrenaline Reuptake Inhibitors 11%
  • Hyperalgesia 8%
  • Hydrotherapy 6%

• Mechanisms and Functional Roles of Orexins’Cardiovascular Effects in the Dorsomedial Hypothalamus

  Hwang, L.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hypothalamus 100%
  • Orexins 78%
  • Neurons 16%
  • Sodium-Calcium Exchanger 10%
  • Neural Pathways 8%

• Mechanisms for Epithelium-Derived Interleukin 33 (Il-33) Up-Regulation and Its Effects on Circulating Fibrocyte Chemotaxis, Proliferation and Differentiation in Patients with Chronic Obstructive Asthma

  Kuo, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanisms of Empaglifozin on Cardiac Metabolism with Electrical and Structural Remodelings: Implications in Cardio-Protection of Sodium Glucose Transporter 2 Inhibitor

  Lee, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • empagliflozin 100%
  • Diabetes Mellitus 36%
  • Sodium-Glucose Transporter 2 Inhibitors 31%
  • Peroxisome Proliferator-Activated Receptors 21%
  • Cardiomyopathies 20%

• Mechanisms Underlying Airway Hypersensitivity Induced by Hydrogen Sulfide

  Lin, Y.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Unmyelinated Nerve Fibers 100%
  • Lung 65%
  • Hypersensitivity 50%
  • Reflex 39%
  • Ankyrins 37%

• Mechanistic Exploration of the Role of SCUBE2 in Suppressing the Generation of Cancer Stem Cells and Its Potential in Developing Novel Therapeutics (III)

  Chao, T.

  5/1/14 → 4/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanistic Insights and Novel Therapeutic Strategy for Nicotine-Induced Ventricular Arrhythmogenesis from the Translational Animal Model of Chronic Obstructive Pulmonary Disease (2/2)

  Chan, C.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanistic Insights Into the Therapeutic Potential of Lithium on Cardiac Remodeling: Targeting the Allostatic Load and Dysregulated Mitochondrial Bioenergetics in Rapid Eye Movement Sleep Deprivation

  Chen, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanistic Studies of Renal Cell Carcinoma: from Rhoa-Mediated Expression of Cd44-Targeting Micrornas to the Development of Biomarkers and Therapies

  Juan, S.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Renal Cell Carcinoma 100%
  • MicroRNAs 67%
  • Biomarkers 15%
  • Simvastatin 14%
  • Epithelial Cells 13%

• Mechanistic Studies of Renal Cell Carcinoma: from Rhoa-Mediated Expression of Cd44-Targeting Micrornas to the Development of Biomarkers and Therapies

  Juan, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Renal Cell Carcinoma 100%
  • MicroRNAs 67%
  • Biomarkers 15%
  • Simvastatin 14%
  • Epithelial Cells 13%

• Mechanistic Studies of Renal Cell Carcinoma: from Rhoa-Mediated Expression of Cd44-Targeting Micrornas to the Development of Biomarkers and Therapies

  Juan, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Renal Cell Carcinoma 100%
  • MicroRNAs 67%
  • Biomarkers 15%
  • Simvastatin 14%
  • Epithelial Cells 13%

• MEKK1/JNK依賴SMAD3活化媒介CXCL12誘導肺部纖維母細胞CTGF表現之探討

  Chen, B.

  6/1/13 → 5/31/14

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• Metabolomic Analysis of Tuberculous Pleural Effusions with Residual Pleural Thickening

  Chung, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pleural Effusion 100%
  • Platelet Activating Factor 90%
  • Small Interfering RNA 21%
  • Epithelial-Mesenchymal Transition 19%
  • Metabolomics 13%

• Metabolomics and Microbiomics Approach in Providing Prediction of Early Puberty and Nutritional Guidance for Children Undergone Pubertal Growth( II )

  Chen, Y.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Metformin抑制TRPA1與P2X3受器所引發的呼吸反射及過度敏感之機制探討

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Microarray Investigation of Global Regulation by speG in Salmonella typhimurium, Human Intestinal Epithelium, and B Lymphocytes in an in vitro M-Cell Model

  Fang, S.

  4/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • cells 100%
  • Salmonella 86%
  • B-lymphocytes 85%
  • Salmonella Typhimurium 68%
  • transposons 39%

• Modulation of Dendritics Cells Differentiation and Maturation by Valproic Acid

  Leu, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Valproic Acid 100%
  • Dendritic Cells 46%
  • Bipolar Disorder 31%
  • T-Lymphocytes 16%
  • Preliminary Data 14%

• Modulation of Tumor Microenvironment by Nucleic Acid Chimeras as a New Paradigm for Adjuvant Cancer Therapy

  Yeh, S.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • neoplasms 100%
  • cytokines 66%
  • neoplasm progression 60%
  • neoplasm cells 55%
  • chimerism 45%

• Modulation of Tumor Microenvironment by Nucleic Acid Chimeras as a New Paradigm for Adjuvant Cancer Therapy

  Yeh, S.

  1/1/12 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • neoplasms 100%
  • cytokines 66%
  • neoplasm progression 60%
  • neoplasm cells 55%
  • chimerism 45%

• Molecular and Immunopathogenesis of Recombinant Toxocara Antimicrobial Peptides in Wound Healing on Skin Lesion Infected by Opportunistic Staphylococcus Aureus and Therapeutic Effects on Systemic Sepsis Caused by Mdrsa in Mice (1/3)

  Fan, C.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Biomarkers Targeting the Metastatic Relapse of Neuroblastoma

  Liu, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neuroblastoma 100%
  • Biomarkers 65%
  • Residual Neoplasm 17%
  • Neoplasm Metastasis 10%
  • Molecular Imaging 9%

• Molecular Biomarkers Targeting the Metastatic Relapse of Neuroblastoma

  Liu, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neuroblastoma 100%
  • Biomarkers 65%
  • Residual Neoplasm 17%
  • Neoplasm Metastasis 10%
  • Molecular Imaging 9%

• Molecular Epidemiological Studies of Arsenical Skin Cancer: Effect of Gwas-Derived Snp Variants and Their Gene Expression on Cancer Risk

  Wu, M.

  8/1/18 → 7/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Skin Neoplasms 100%
  • Arsenic 97%
  • Single Nucleotide Polymorphism 31%
  • Methylation 26%
  • Neoplasms 24%

• Molecular Epidemiological Study of Renal Cell Carcinoma - Arsenic Methylation Capability, 8OHdG and Polymorphism of IRS and RAAS Exploration

  Hsueh, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Arsenic 100%
  • Renal Cell Carcinoma 62%
  • Methylation 54%
  • Insulin Receptor 26%
  • Enzymes 25%

• Molecular Epidemiological Study of Renal Cell Carcinoma---Arsenic Methylation Capability, 8-OHdG and Polymorphism of IRS and RAAS Exploration

  Hsueh, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Arsenic 100%
  • Renal Cell Carcinoma 62%
  • Methylation 54%
  • Insulin Receptor 26%
  • Enzymes 25%

• Molecular Epidemiology, Related Risk Factors and Phylogenetic Analysis of Epilepsy-Causing Neurotoxocariasis or Neurocysticercosis in the Kingdom of Eswatini, Africa

  Fan, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Immunopathogenesis of Dermatophagoides Pteronyssinus (Der P1) Allergen on the Progression of Pulmonary Toxocariasis-Causing Asthma and Fibrosis by Proteomic Approaches

  Fan, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Toxocariasis 100%
  • Toxocara canis 85%
  • Lung 52%
  • Ovum 50%
  • Asthma 44%

• Molecular Insights into Ketogenic Diet on Cardiac Metabolic Disorders in Diabetic Cardiomyopathy

  Lee, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Ivestigation of the Electron Transfer Flavoprotein Dehydrogenase Mutation Induced Mitochondrial Dysfunction and Metabolic Defects

  Kao, S. & Hsu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • acyl-CoA dehydrogenase 100%
  • flavoproteins 97%
  • electron transfer 79%
  • droplets 39%
  • myoblasts 31%

• Molecular Mechanism in Amyloid Peptide-Induced Cerebral Endothelial Cell Apoptosis:Role of Hdac and Ampk

  Hsu, M.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Acetylation 100%
  • Histone Deacetylases 95%
  • Endothelial Cells 60%
  • Cerebral Amyloid Angiopathy 57%
  • Sirtuins 55%

• Molecular Mechanism in Amyloid Peptide-Induced Cerebral Endothelial Cell Apoptosis---Role of HDAC and AMPK

  Hsu, M.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylases 100%
  • Acetylation 90%
  • Endothelial Cells 54%
  • Cerebral Amyloid Angiopathy 51%
  • Sirtuins 49%

• Molecular Mechanism of the Effect of Cafestol on Growth Factor-Induced Cardiomyocyte Hypertrophy

  Liu, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • cafestol 100%
  • urotensin II 55%
  • Cardiac Myocytes 49%
  • Hypertrophy 40%
  • Intercellular Signaling Peptides and Proteins 21%

• Molecular Mechanisms of a Novel Aliphatic Hydroxamate, WMJ-S-001, in Suppressing Colorectal Cancer Progression---The Causal Role of AMPK-p53 Modification-miRNAs Cascade

  Hsu, M.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • WMJ-S-001 100%
  • Neoplasms 11%
  • MicroRNAs 10%
  • Colorectal Neoplasms 8%
  • Lymphangiogenesis 7%

• Molecular Mechanisms of Anti-Angiogenic Effects of 3-Methylcholanthrene, an Aryl-Hydrocarbon Receptor Agonist, in Relation to Cell Proliferation, Adhesion and Migration of Endothelial Cells, and Its Therapeutic Intervention Using Resveratrol

  Juan, S.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Methylcholanthrene 100%
  • Aryl Hydrocarbon Receptors 79%
  • Resveratrol 26%
  • Xenobiotics 24%
  • PTEN Phosphohydrolase 16%

• Molecular Mechanisms of Anti-Inflammatory Effects of Intravenous Anesthetic Agent Ketamine on Lipopolysaccharide-Activated Macrophages

  Chen, T. & Chen, R.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • ketamine 100%
  • lipopolysaccharides 80%
  • macrophages 39%
  • Toll-like receptors 32%
  • cytokines 32%

• Molecular Mechanisms of C/EBP-Β Regulates microRNA-16 and Its Clinical Application

  Chen, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Acute Kidney Injury 78%
  • Transcription Factors 68%
  • Reperfusion Injury 17%
  • Kidney 14%

• Molecular Mechanisms of C/EBP-Β Regulates microRNA-16 and Its Clinical Application(2/2)

  Chen, H.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Acute Kidney Injury 78%
  • Transcription Factors 68%
  • Reperfusion Injury 17%
  • Kidney 14%

• Molecular Mechanisms of Helicobacter Pylori Virulence Factors for Regulating Inflammation Responses in Epithelial Cells and Macrophages

  Lin, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Helicobacter pylori 100%
  • pylorus 80%
  • macrophages 74%
  • inducible nitric oxide synthase 44%
  • cholesterol 36%

• Molecular Mechanisms of Helicobacter Pylori Virulence Factors for Regulating Inflammation Responses in Epithelial Cells and Macrophages

  Lin, H.

  4/1/11 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Helicobacter pylori 100%
  • pylorus 80%
  • macrophages 74%
  • inducible nitric oxide synthase 44%
  • cholesterol 36%

• Molecular mechanisms of propofol-involved protection against ischemia brain injuries

  Chen, T.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Propofol 100%
  • Ischemia 76%
  • Brain Injuries 75%
  • Reperfusion 34%
  • Mitogen-Activated Protein Kinases 30%

• Molecular Mechanisms of Propofol-Involved Protection against Ischemia Brain Injuries

  Chen, T.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Propofol 100%
  • Ischemia 76%
  • Brain Injuries 75%
  • Reperfusion 34%
  • Mitogen-Activated Protein Kinases 30%

• Molecular Mechanisms of Propofol-Involved Protection against Ischemia Brain Injuries 全文電子檔： 全文連結1

  Chen, T.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Propofol 100%
  • Ischemia 76%
  • Brain Injuries 75%
  • Reperfusion 34%
  • Mitogen-Activated Protein Kinases 30%

• Molecular Mechanisms of Secretory Rab Gtpase 3c in Promoting Colon Cancer Metastasis

  Chen, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of Secretory Rab Gtpase 3c in Promoting Colon Cancer Metastasis(1/3)

  Chen, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms of Secretory Rab Gtpase 3c in Promoting Colon Cancer Metastasis(3/3)

  Chen, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Mechanisms Underlying Statins-Suppressed Colorectal Cancer Progression: Role of P53 Family Proteins and Microrna

  Hsu, M.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors 100%
  • Simvastatin 61%
  • Colorectal Neoplasms 49%
  • MicroRNAs 43%
  • Cell Death 31%

• Molecular Mechanism Underlying Progesterone-Regulated p27 Gene Expression

  Hsu, S.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • transcription (genetics) 100%
  • angiogenesis 82%
  • 5' untranslated regions 73%
  • promoter regions 72%
  • 3' untranslated regions 72%

• Molecular Pathogenesis of Cerebral Neuroglia Cells on Tjps and Biabs Expressions as Well as Ups Dysfunction in Neurotoxocariasis That Develops Progressively into Alzheimer's-Like Diseases as Assessed by SP/NK-1R Inhibition

  Fan, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Substance P 100%
  • Toxocara canis 69%
  • Astrocytes 64%
  • Tight Junction Proteins 59%
  • Blood-Brain Barrier 56%

• Molecular Pathogenesis of Cerebral Neuroglia Cells on TJPs and Biabs Expressions as Well as UPS Dysfunction in Neurotoxocariasis That Develops Progressively into Alzheimer's-Like Diseases as Assessed by SP/NK-1R Inhibition

  Fan, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Substance P 100%
  • Tight Junction Proteins 74%
  • Toxocara canis 69%
  • Astrocytes 64%
  • Blood-Brain Barrier 56%

• Molecular Pathogenesis of Progression of Cerebral toxocariasis into Alzheimer’s-Like Disease Affected by Dysfunctional Regulation from Impaired UPS and ALS That Lead to Aberrant Βeta-Amyloid Generation and Metabolism in Brain

  Fan, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Toxocariasis 100%
  • Toxocara canis 75%
  • Proteasome Endopeptidase Complex 60%
  • Ubiquitin 51%
  • Amyloid Precursor Protein Secretases 45%