Projects per year
- 1,700 - 1,750 out of 2,491 results
Search results
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Finished
Evaluation of Clinical Feasibility of Quantitative MR Perfusion Imaging and Its Calibration
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Short-Chain Fatty Acids Act as Anti-Allergic Regulators on Immune Effector Cells and Exert Immune-Modulatory Effects on Ovalbumin-Induced Allergic Diseases in Mice
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Studies on the Role of ORMDL3 in Thrombin-Induced IL-8/CXCL8 Expression and Airway Inflammation
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Evaluate the Molecluar Mechanims and Clinical Application on Atf3 Regulated microRNAs
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Role of CISD2 in the Female Reproductive System of Mammal
Chang, H.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Effect of Long Acting GnRH Agonist Treatment on Mitochondrial Function in
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Role of Oxidative Stress-triggered Redox Adaptation Mechanism and Genetically Endowed Expression Profile of Antioxidant Enzymes in the modulation of Intrinsic and Acquired Chemoand Radio-resistance of Human Hepatocellular Carcinoma Cells
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects of Uteroplacental Insufficiency and Hyperoxia on Lung Development and Epigenetic Alterations in the Rat Offspring
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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粒狀空氣污染物所產生的氧化壓力對慢性阻塞性肺疾病患者的泛素-蛋白酉每平衡系統之影響:探討氧化壓力,異常發炎以及蛋白質氧化之關係
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Effect of Endothelin-1 on Myofibroblast Transformation of Pleural Mesothelial Cells and Its Implications for Pleural and Pulmonary Fibrosis
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Investigation of Glioblastoma Cell-Secreted microRNA Signatures and Their Functional Effects on Tumor Angiogenesis
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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An Investigation of the Effects of Tea Component on the Inhibition of Leukocyte Nicotinic Acetylcholine Receptor Expression on Breast Cancer Patients
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Role of ADAM 17 in Hypoxia-Induced CTGF Expression and Pulmonary Fibrosis (II)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Relationship and Predictors of Electrocardiography, Inflammatory Markers, Clinical Features in Older Bipolar and Schizophrenia Patients Concurrent with Coronary Heart and Cerebro-Vascular Diseases
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Development of Vector-Borne Disease Forecasting Models Using Satellite Remote Sensing Techniques
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Dissected the Role of Glucosed-Regulated Portein 78 in the Progression, Metastasis and Therapy of Colorectal Cancer
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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組蛋白去甲基酉每JARID1B基因在肺腺癌之腫瘤形成與影響腫瘤生物行為機轉之探討(1/2)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Chitosan Nanoparticle as a Macrophage-Targeting Drug Delivery Carrier
8/1/14 → 8/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Study the Function and Regulation of miRNAs in Pancreatic Cancer Progression (I)
Huang, M.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關,曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能,包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義,這也促使我們想要釐清E1A抑制癌症的機制。因此,我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣,並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示,E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中,GRP78所扮演的生物功能及其調控的機轉。為了達到此目的,我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標: 目標一:探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二:研究E1A抑制GRP78表現之分子機轉 目標三:於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四:探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外,藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Study on the Mechanism of Cross-Talk between Ahr and Autophagy, and Autophagy---Associated Physiological or Pathological Phenomenon on Vascular and Airway Systems (I)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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A Study on Trans-Neuronal Striato-Nigral Degeneration-Induced Movement Disorders after Stroke---Evaluation with Grey Matter Suppression Ir and Diffusion Tensor Imaging (III)
8/1/14 → 10/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Study of Therapeutic Effects for Stroke with Phenserine, an Amyloid Precursor Protein Inhibitor, in Rodent Focal Cerebral Ischemia Model(2/3)
Chang, C. & Chiang, Y.
8/1/14 → 7/31/15
Project: A - Government Institution › a - National Health Research Institutes
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Application of Scaffold in Ovarian Transplantation for Female Fertility Preservation---An in vivo Transgenic Mouse Model (I)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Studies of Anti-Cancer Activity of Folic Acid
Lee, W.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Highly Reliable Surface-Enhanced Raman Scattering Sensors
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effect of Vasopressin Receptor Agonist and Antagonist on Pulmonary Vein and Atrial Arrhythmogenesis
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Molecular Epidemiological Study of Renal Cell Carcinoma---Arsenic Methylation Capability, 8-OHdG and Polymorphism of IRS and RAAS Exploration
Hsueh, Y.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Investigation of Mechanisms of SSRI Antidepressants and GABAAR Modulators Inhibit High-Grade Glioma Invasion
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects of Direct Renin Inhibitor on Visceral Adipose Tissue and Vascular Remodeling of Fructose-Fed Hypertensive Rats
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Kidney Injury and Heat Shock Protein Modulate the Atrial Electrophysiological Characterisitcs
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Association Study of Persistent Metabolic Syndrome, Inflammatory Markers, Adipose Markers and Mild Cognitive Decline
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Evaluate the Radio-Biological Roles of miR-17-5P in Oral Cancer Cell Line OC3
Wu, S.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Molecular Mechanisms of a Novel Aliphatic Hydroxamate, WMJ-S-001, in Suppressing Colorectal Cancer Progression---The Causal Role of AMPK-p53 Modification-miRNAs Cascade
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Influence of Porphyromonas gingivalis Groel in Vascular Cells
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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榖胱甘月太硫轉移酉每參與乳癌致癌之分子機制探討(3/3)
Wu, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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肝醣合成酉每激酉每3於登革病毒感染單核吞噬細胞的潛在角色(2/3)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Neurotrophic/Neuroprotective Role of GIP in Cellular and Rodent Models of Mild Traumatic Brain Injury (III)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects of Indoor Air Quality Improvement on Cardiovascular Health in General Population
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects of Ultrafine Particles on Cardiopulmonary System: a Population-Based Approach
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Characterization of 5-Hydroxymethylcytosine and Ten-to-Eleven Translocation Gene (TET) in Cervical Cancer
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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建立癌症新診斷病人健康素養評量工具與評估計畫(103-104年)
Bai, C. & Yang, K.
6/4/14 → 6/3/15
Project: A - Government Institution › c - Ministry of Health and Welfare
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Tetrac於初代大腸癌細胞中強化白藜蘆醇誘導之
6/1/14 → 5/31/15
Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital
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腦外傷臨床生物標幟之研究
6/1/14 → 5/31/15
Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital
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單碳循環路徑與精神分裂症患者之精神病理學和代謝異常的關係
6/1/14 → 5/31/15
Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital
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探討微核醣核酸miR-520h在三重陰性乳癌的角色
6/1/14 → 5/31/15
Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital
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探討DPP-IV抑制劑對傷口癒合過程中血管新生之影響
6/1/14 → 5/31/15
Project: C - Project of Alliance › p - Taipei Medical University Hospital
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To Study the Correlation between Serum Markers of Oxidative Stress, Inflammation, and Endocrine-Disrupting Chemicals (Edcs) and Their Impact on the Menstrual Cycle and Reproductive Hormone in Taiwanese Women.
Hsu, M.
6/1/14 → 5/31/15
Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital
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探討以特定微型核糖核酸16作為顯影劑引發之腎病變的標的
6/1/14 → 5/31/15
Project: C - Project of Alliance › p - Taipei Medical University Hospital
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CD44和RhoA蛋白在腎細胞癌之角色並鑑別miRNAs對CD44的誘導作用之影響
6/1/14 → 5/31/16
Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital