School of Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2026

• 3 Not started
• 222 Active
• 2067 Finished

Projects per year

Search results

• Finished

  Investigated the Role of Mir-200 Family in the Prognostic and Therapeutic of Hcc and Dissected the Possible Mechanism

  Wang, W.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • MicroRNAs 22%
  • Hypoxia 20%
  • Neoplasms 14%
  • Hep G2 Cells 9%

• Translational Relevance and Mechanism of Glucose Transporter 3 in Colon Cancer Metastasis: Focus on Tumor Microenvironment and Developing Therapeutics(1/3)

  Lin, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Restoration of Mitochondrial Function: in Search of Therapeutic Agents for Metabolic Myopathy

  Kuo, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Muscular Diseases 100%
  • Organelle Biogenesis 52%
  • Electric Stimulation 37%
  • Nutrients 35%
  • Smegmamorpha 31%

• Identification of Estrogen Receptor Regulates Stemness Properties of Endometrial Stem Cells and Its Clinical Significance in Endometriosis.

  Au, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • stem cells 100%
  • endometrium 74%
  • chocolate 40%
  • estrogens 30%
  • tissues 29%

• Investigating Immunopathologic Effects of Blimp-1 in the Brain of Mice Infected with Angiostrongylus Cantonensis by Evaluated Model of Nuclear Medical Imaging

  Cheng, P.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Positive Regulatory Domain I-Binding Factor 1 100%
  • Angiostrongylus cantonensis 50%
  • Angiostrongyliasis 29%
  • Brain 17%
  • Fluorodeoxyglucose F18 13%

• Study of Prevention, Control, Genotyping and Risk Factors of Intestinal Parasitic Infections and Head Lice in Schoolchildren in Cambodia(2/3)

  Liao, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Association between Plasma Folate and Selenium Concentrations, Gene Polymorphisms of Selenoprotein and One Carbon Metabolism Related Enzymes and Developmental Delay in Preschool Children

  Hsueh, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Preschool Children 100%
  • Arsenic 88%
  • Selenoproteins 47%
  • Selenium 45%
  • Cystathionine 38%

• 新聘教師研究補助

  Kuan, Y.

  8/1/18 → 7/31/20

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• The Anti-Fibrotic Activity of Sodium Glucose Co-Transporters (Sglts) Inhibition: Therapeutic Potential in Diabetes Mellitus Cardiomyopathy

  Lee, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cardiomyopathies 100%
  • Diabetes Mellitus 99%
  • 3-(3-(4-(3-(glucopyranosyloxy)-5-isopropyl-1H-pyrazol-4-ylmethyl)-3-methylphenoxy)propylamino)propionamide 82%
  • empagliflozin 70%
  • (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(methylthio)tetrahydro-2H-pyran-3,4,5-triol 69%

• Reflective Implementation Deepens the Understanding of Life through the Visit to Family Members of the Silent Mentor.

  Chiou, R.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • love 100%
  • learning 95%
  • student 82%
  • death 81%
  • medical student 50%

• Metabolomic Analysis of Tuberculous Pleural Effusions with Residual Pleural Thickening

  Chung, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pleural Effusion 100%
  • Platelet Activating Factor 90%
  • Small Interfering RNA 21%
  • Epithelial-Mesenchymal Transition 19%
  • Metabolomics 13%

• Therapeutic Potentials of Peptide-Based Cytokine Binding Decoy against Sepsis and Its Effects on Modulating Inflammation, Oxidation, Apoptosis, Autophagy and Inflammasome

  Huang, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sepsis 100%
  • Peptides 37%
  • Cytokine Receptors 31%
  • Cytokines 24%
  • Inflammasomes 23%

• Pharmacological Mechanisms of the Novel Aliphatic Hydroxamate Derivative Wmj-J in Suppressing Colorectal Cancer Progression: the Role of Phosphatase, Micrornas and Survivin Modulation

  Hsu, M.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • MicroRNAs 70%
  • WMJ-S-001 67%
  • HCT116 Cells 54%
  • Survivin 50%

• The Investigation of Anti-Neuroinflammatory Constituents from Fungal Species and Their Protective Profiles in the Retinal Diseases(1/3)

  Hsiao, G.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pank2 Mutations and the Neurodegeration: Investigating the Pathogenetic Mechanisms and Identifying the New Treatment

  Hong, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Genetic Polymorphisms on Efficacy and Safety of Opioid Analgesics in Patients with Postoperative Pain in a Taiwanese Population

  Tai, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Opioid Analgesics 100%
  • Genetic Polymorphisms 59%
  • Analgesics 38%
  • Pain Management 34%
  • Postoperative Pain 22%

• 中風後丘腦神經網路調節機制之轉譯影像研究(3/3)

  Chen, C.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thalamus 100%
  • Stroke 83%
  • Thalamic Nuclei 52%
  • Cerebral Infarction 43%
  • Gait 38%

• Effects of Cafestol on Cardiac Hypertrophy.

  Liu, J.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Application of the Combination of Decelluarized Extracellular Matrix Grafted by Graphene and Bone Marrow Aspirate Concentrates on the Healing of Partial Tear of Anterior Cruciate Ligament(3/3)

  Chen, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • anterior cruciate ligament 100%
  • bone marrow 53%
  • extracellular matrix 44%
  • concentrates 35%
  • graphene 28%

• Cinacalcet Hydrochloride Improves Bone Disorder in Renal Osteodystrophy by Regulating Endoplasmic Reticulum Stress and Autophagy

  Zheng, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cinacalcet 100%
  • Chronic Renal Insufficiency 66%
  • Chronic Kidney Disease-Mineral and Bone Disorder 60%
  • Endoplasmic Reticulum Stress 48%
  • Bone and Bones 38%

• Exploring the Potential Impacts of Maternal Early-Life Sleep Deprivation on Metabolic Function of the Offspring(III)(3/3)

  Chang, H.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploring the Potential Impact of Periodontitis on the Induction or Development of Parkinson’S Disease: Utilizing Platelet Lysate as a Possible Therapeutic Strategy(2/2)

  Chang, H.

  8/1/18 → 12/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Investigate the Role of Rbm3 in Therapeutic Hypothermia Mediated Neuroprotection in Ischemia Stroke(2/3)

  Yang, C. H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of Reactive Dicarbonyl Species-Induced Epithelial to Mesenchymal Transition in Diabetes Exacerbating Pulmonary Fibrosis (Ii)－Clarification of Age/Rage-Independent Pathways and Analysis of Correlation with Clinical Outcome(2/2)

  Hsieh, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pulmonary Fibrosis 100%
  • Epithelial-Mesenchymal Transition 72%
  • Pyruvaldehyde 49%
  • Receptor for Advanced Glycation End Products 30%
  • Glyoxal 27%

• Psychophysiological Effects of Lactobacillus Plantarum Ps128 in Patients with Major Depressive Disorder: a Pilot Study of 8-Week Open Trial

  Chen, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lactobacillus plantarum 100%
  • Probiotics 77%
  • Gastrointestinal Microbiome 71%
  • Inflammation 53%
  • Permeability 46%

• Diabetes and the Risk of Parkinson'S Disease&Quot; Investigate the Association between Insulin Resistance and Parkinson'S Disease-Second Term Project

  Hong, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• New Brain Cortical Electrical Stimulation Technology for the Neurorehabilitation Therapy of Bladder Dysfunction in the Parkinson’S Disease Animal Model(2/3)

  Peng, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of novel genetic mutations for antibiotic resistance, intracellular upregulated Salmonella genes within host cells, and the mechanisms of yqiC-induced host innate immunity for combating Salmonella infection (3/3)

  Fang, S.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Salmonella 100%
  • antibiotic resistance 37%
  • ciprofloxacin 34%
  • point mutation 33%
  • genes 26%

• Thermodynamic Stability and Folding Kinetics of Membrane Proteins(2/2)

  Chang, Y.

  8/1/18 → 9/30/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • protein 100%
  • membrane 79%
  • trapping 76%
  • folding 48%
  • thermodynamics 22%

• A Translational Investigation of the Role of Myc/Pd-L1/Akt Axis as a Therapeutic Target for Treating Glioblastoma Multiforme

  Lin, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Dose Effect of Extended-Release Metformin on Metabolic Parameters and Neurocognitive Function Treated by Clozapine or Olanzapine in Patients with Schizophrenia: a Randomized, Double-Blinded, Placebo-Controlled Trial

  Lu, M.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Metformin 100%
  • Olanzapine 32%
  • Clozapine 31%
  • Schizophrenia 27%
  • Placebos 22%

• Role of Hbx and Androgen Receptor in Regulating Senp1/Stemess-Related Properties in Hbv-Related Hcc and Its Clinical Impact

  Huang, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatitis B virus 100%
  • Hepatocellular Carcinoma 65%
  • Hep G2 Cells 23%
  • Hepatitis B 21%
  • Neoplasms 19%

• The Protective Role of Hmg-Coa Reductase Inhibitor，Statins，In Postoperative Complications and Survival of Critically Ill Subjects(2/3)

  Chen, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 樺木酸可作為IRE1/XBP1/Herp路徑抑制劑以阻斷膠質母細胞瘤的增殖和存活(1/3)

  Lo, W.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Molecular Epidemiological Studies of Arsenical Skin Cancer: Effect of Gwas-Derived Snp Variants and Their Gene Expression on Cancer Risk

  Wu, M.

  8/1/18 → 7/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Skin Neoplasms 100%
  • Arsenic 97%
  • Single Nucleotide Polymorphism 31%
  • Methylation 26%
  • Neoplasms 24%

• Investigation on the Potentials of Water Extracts Obtains from Ganoderma Lucidum Fruit Body for Inhibition of Colorectal Cancer (Crc) Mediated by Regulating Gut Microbiota

  Tai, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • colorectal neoplasms 100%
  • intestinal microorganisms 54%
  • neoplasms 41%
  • Ganoderma lucidum 36%
  • neoplasm progression 20%

• Targeting Hepatitis C Virus-Induced Hepatocellular Carcinoma with Precision Medicine-Tailored Oncolytic Measles Virus(1/3)

  Lin, L. T.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Overcoming Chemo-Resistance in Glioma-Bearing Rats by Using Sequential and Biodegradable Multidrug-Loaded Nanofibrous Membranes(2/2)

  Tseng, Y.

  8/1/18 → 10/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Nanofibers 100%
  • Carmustine 85%
  • Temozolomide 63%
  • Glioblastoma 50%
  • Membranes 30%

• Effects of Long-Term Exposure to Indoor Air Pollution and Indoor Air Quality Improvement on Cardiovascular Health in General Population(1/2)

  Chuang, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• In Vi Vo and in Vi Tro Screening of the Dyslipidemic Antihypertensives, Studying the Mechanism to Modulate Signaling Srebp and Ppar in the Renal Cells, and Investigating the Cotherapy with Mountain Celery Seed Aqueous Extract in Reducing Worsen Renal F(3/3)

  Chen, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Apium 100%
  • Seeds 63%
  • Kidney 60%
  • Antihypertensive Agents 47%
  • Sterol Regulatory Element Binding Proteins 31%

• Investigation of the Relationship between Gait Disturbance and Cognitive Impairment

  Kuan, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Gait 100%
  • Cognitive Dysfunction 98%
  • Dementia 87%
  • Cognition 59%
  • Alzheimer Disease 46%

• Investigations of Corneal Endothelial Cells on Biomaterials

  Wang, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Machnism of Calcium Containing Cystals in Bone Remodeling

  Chang, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • bones 100%
  • osteoclasts 77%
  • arthritis 67%
  • osteoblasts 43%
  • calcium 31%

• Evaluating the Role of Fibrinolytic Proteins on Insulin Secretion and Regeneration of Islet Cells in Obesity and Type 2 Diabetes during Exercise

  Wu, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Plasminogen Activators 100%
  • Urokinase-Type Plasminogen Activator 96%
  • Type 2 Diabetes Mellitus 74%
  • Insulin Secretion 56%
  • Exercise 55%

• Autolysin Regulatory Machinery of Streptococcus Mutans in Bacterial Survival and Biofilm Formation in Infective Endocarditis

  Jung, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Endocarditis 100%
  • Streptococcus mutans 24%
  • Ions 22%
  • N-Acetylmuramoyl-L-alanine Amidase 20%
  • Biofilms 20%

• Catalpol Acts as an Immunomodulator on Immune Cells and Exerts Anti-Allergic Effects on Ovalbumin-Induced Allergic Diseases in Mice

  Lee, Y.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • catalpol 100%
  • Mast Cells 16%
  • Asthma 15%
  • Immunoglobulin E 15%
  • Dendritic Cells 12%

• Studies on the Potential Antitumor Mechanisms of Hyaluronan Synthase Involved in Early Onset Breast Tumor Tissues(2/3)

  Tu, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Niche Inflammatory Cytokine and Epigenetic Regulation in Expressions of Pluripotent Transcription Factor Oct4 and Sorafenib Refractoriness in Hbv-Related Hepatocellular Carcinoma and Its Clinical Implication.(I)(1/3)

  Huang, Y.

  8/1/18 → 10/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation on Molecular Pathogenic Mechanisms and Therapy for Park14 Using Pla2g6 Knockin Mouse Model

  Yeh, T.

  8/1/18 → 12/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Traumatic Brain Injury: Degenerative Mechanisms, Phenserine Treatment and Exosome Biomarkers of Response

  Chiang, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • phenserine 49%
  • Alzheimer Disease 34%
  • Exosomes 29%
  • Oxidative Stress 14%