Projects per year
- 550 - 600 out of 2,491 results
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開發溶瘤麻疹病毒載體抗癌治療之癌細胞標的預篩檢研究平台暨初步抗癌效力評估
6/1/14 → 5/31/15
Project: C - Project of Alliance › p - Taipei Medical University Hospital
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懷孕及哺乳母鼠給予尼古丁對小鼠心臟細胞分化與增殖的影響
6/1/14 → 5/31/15
Project: C - Project of Alliance › p - Taipei Medical University Hospital
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探討DPP-IV抑制劑對傷口癒合過程中血管新生之影響
6/1/14 → 5/31/15
Project: C - Project of Alliance › p - Taipei Medical University Hospital
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第二型糖尿病人與高血壓合併腎衰竭病人之脂蛋白對血管內皮前驅細胞功能之影響。
6/1/14 → 5/31/15
Project: C - Project of Alliance › p - Taipei Medical University Hospital
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自體免疫疾病之發炎和骨質流失之臨床和流病研究
6/1/14 → 5/31/15
Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital
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探討microRNA494與活化轉錄因子3的關係及在肥胖引糖尿病發腎病變中所扮演之生理角色
6/1/14 → 5/31/15
Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital
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探討缺氧狀態下氯黴素抑制缺氧誘導因子活性之分子機轉與新應用
6/1/14 → 5/31/16
Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital
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檢測家族性淋巴水腫的致病基因
6/1/14 → 5/31/16
Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital
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小分子團水對降低血脂膽固醇之動物模式與其在粥狀動脈硬化症之臨床意義探討
6/1/14 → 5/31/15
Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital
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探討胞外基質Laminin與類胰島素生長因子-1於精原幹細胞自我更新之訊息傳遞機制
6/1/14 → 5/31/15
Project: C - Project of Alliance › p - Taipei Medical University Hospital
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探討以特定微型核糖核酸16作為顯影劑引發之腎病變的標的
6/1/14 → 5/31/15
Project: C - Project of Alliance › p - Taipei Medical University Hospital
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慢性呼吸道疾病的氧化壓力、發炎反應、表觀遺傳學之研究
6/1/14 → 5/31/15
Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital
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建立癌症新診斷病人健康素養評量工具與評估計畫(103-104年)
Bai, C. & Yang, K.
6/4/14 → 6/3/15
Project: A - Government Institution › c - Ministry of Health and Welfare
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Unraveling the Impact of Deletion of Androgen Receptor on Brain Trauma
Yang, L.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Serum Free Cultivation of Multi-Layered Oral Mucosa Epithelial Cell Sheet for Autologous Corneal Epithelium Repairing and Its Animal Model
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Reflex Pelvic Floor Muscle Activities in Women with Urinary Incontinence (II)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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探討芳香烴受體(AhR)改變血管內皮細胞功能之新角色：經由表觀基因或後轉譯修飾(細胞週期蛋白/內皮細胞一氧化氮合成酉每)的調控與白蘆黎醇/史達汀臨床治療及應用(2/3)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Role of ADAM 17 in Hypoxia-Induced CTGF Expression and Pulmonary Fibrosis (II)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Development of a Computerized Adaptive Testing of the Health Literacy in Stroke Rehabilitation
Hou, W.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Molecular Mechanisms of a Novel Aliphatic Hydroxamate, WMJ-S-001, in Suppressing Colorectal Cancer Progression---The Causal Role of AMPK-p53 Modification-miRNAs Cascade
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Study the Function and Regulation of miRNAs in Pancreatic Cancer Progression (I)
Huang, M.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Influence of Porphyromonas gingivalis Groel in Vascular Cells
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Functional Investigation of Heat Shock Protein in Esophageal Squamous Cell Cancer with Implications in Prognostic Prediction and Therapeutic Targeting
Tzao, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effect of Vasopressin Receptor Agonist and Antagonist on Pulmonary Vein and Atrial Arrhythmogenesis
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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New Strategies of Parkinson’s Disease Treatment
8/1/14 → 12/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Study of Therapeutic Effects for Stroke with Phenserine, an Amyloid Precursor Protein Inhibitor, in Rodent Focal Cerebral Ischemia Model(2/3)
Chang, C. & Chiang, Y.
8/1/14 → 7/31/15
Project: A - Government Institution › a - National Health Research Institutes
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CXCL5/CXCR2/JNK Axis Is the Shared Pathway of Neuroinflammation and Microvascular Damage That Contributes to White Matter Injury in the Immature Brain
Huang, C.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Role of CISD2 in the Female Reproductive System of Mammal
Chang, H.
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Neurotrophic/Neuroprotective Role of GIP in Cellular and Rodent Models of Mild Traumatic Brain Injury (III)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Relationship between Lumbar Vertebral Perfusion and Fat Marrow Content in Normal Subjects, Osteoporosis and Bone Metastases Using DCE-MRI and Fat-Water Separation
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Effects of Metabolic Abnormalities on Cognitive Function in Schizophrenic Patients
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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組蛋白去甲基酉每JARID1B基因在肺腺癌之腫瘤形成與影響腫瘤生物行為機轉之探討(1/2)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects of Central Neuromodulation with Functional Electrical Stimulation on Bladder Functions in Traumatic Brain Injured Rats
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Effect of Long Acting GnRH Agonist Treatment on Mitochondrial Function in
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects of Functional Electrical Stimulation Cycling and Central Neuromodulation on Motor Control in Stroke
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Chitosan Nanoparticle as a Macrophage-Targeting Drug Delivery Carrier
8/1/14 → 8/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Therapeutic Strategies for Traumatic Brain Injury with Novelly Desinged Drugs (III)
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Effect of Muscle Strength Training on Body Composition and Sarcopenic Obesity among the Female Overweight Elderly
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects of Uteroplacental Insufficiency and Hyperoxia on Lung Development and Epigenetic Alterations in the Rat Offspring
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Kidney Injury and Heat Shock Protein Modulate the Atrial Electrophysiological Characterisitcs
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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An Investigation of the Effects of Tea Component on the Inhibition of Leukocyte Nicotinic Acetylcholine Receptor Expression on Breast Cancer Patients
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Study of Nano-Size Memberane Tube for Tendon to Bone in Anterior Cruciate Ligament Reconstruction
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Effects of Indoor Air Quality Improvement on Cardiovascular Health in General Population
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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臨床醫學與生命倫理研究組織與參與設計人才培育計劃
Tsai, D.
8/1/14 → 7/31/15
Project: A - Government Institution › d - Ministry of Education
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Mechanisms Underlying Airway Hypersensitivity Induced by Hydrogen Sulfide
8/1/14 → 10/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Evaluation of Clinical Feasibility of Quantitative MR Perfusion Imaging and Its Calibration
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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Analysis the Role of Satellite Cell during Denervation Induced Muscular Atrophy and a Trail of Transplantation of Adipocyte Derived Myogenic Stem Cells
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology
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The Effects of Adipose-Derived Stem Cells on Denervated Rat Skeletal Muscle Atrophy
8/1/14 → 7/31/15
Project: A - Government Institution › b - Ministry of Science and Technology