School of Medical Laboratory Science and Biotechnology

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2020 2021 2022 2023

• 8 Active
• 170 Finished

Projects per year

Search results

• Finished

  長期暴露低劑量塑化劑對肝癌藥物 （sorafenib）感受性的影響

  Liao, Y.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎PDI抑制劑誘導鐵死亡之研究

  Liang, Y.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 粒線體衍生肽對於細胞自噬作用的影響

  Kao, S.

  7/1/22 → 2/28/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• 嵌合抗原受體T細胞用於治療人類卵巢癌的免疫療法(3/3)

  Liu, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 腸道菌叢-腸道代謝體-宿主細胞轉錄後事件組成之調控網絡於維持腸道平衡或誘發腸道細胞癌化特性之探究

  Lin, J.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討內質網氧化還原酶-1a在胰導管腺癌上皮細胞間質轉化過程所扮演的角色

  Liang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討NPC2基因調控肝癌細胞內游離型膽固醇恆定在sorafenib抗藥性之角色(3/3)

  Liao, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 裝載GM-CSF及標靶奈米粒子疫苗之水膠複合系統用於原位募集並活化樹突細胞以增強腫瘤特異性免疫反應達到抑制癌症轉移之功效(1/3)

  Pan, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探究粒線體衍胜肽對粒線體功能障礙的細胞保護作用(1/3)

  Kao, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以尿?雙磷酸葡萄糖醛酸基轉移?2B7 (UGT2B7) 開發新穎三陰性乳癌標靶治療策略(2/3)

  Lee, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 組織胺甲基化轉換酵素(HNMT)輔助臨床醫師鑑別乳癌病患作為Herceptin療效評估之新穎分子標記(3/3)

  Ho, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯 研究-乳癌細胞α9尼古丁受體/HER2複合體作為RNA奈米藥物治療HerceptinR抗藥 性之機制探討(2/3)

  Ho, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Artemisia santolinifolia對頭頸癌細胞生長抑製及其機制研究

  Liu, J.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以玻尿酸合成酶為平台探討RNA適體奈米質粒抑制乳癌之機制

  Ho, Y.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• miR-1作為非小細胞肺癌對歐洲紫杉醇敏感性的調節機制探討

  Liu, J.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討酮體對肝癌細胞sorafenib感受性影響

  Liao, Y.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討ERO1α經由c-Met調控腫瘤細胞移動的分子機制

  Liang, Y.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以CRISPR/Cas9建立exosome-free研究模式探討外泌體(exosome)調控三陰性乳癌轉移機制

  Lee, C.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以CRISPR/cas9開發三陰性乳癌轉移中iPS相關基因作為標靶研究平台

  Lee, C.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發ㄧ奈米粒子水膠複合系統作為手術後的DNA疫苗以預防癌症之復發

  Pan, W.

  11/1/20 → 10/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新聘教師研究補助

  Pan, W.

  10/1/20 → 9/30/21

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 以尿苷雙磷酸葡萄糖醛酸基轉移酶2B7 (UGT2B7) 開發新穎三陰性乳癌標靶治療策略(1/3)

  Lee, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討NPC2基因調控肝癌細胞內游離型膽固醇恆定在sorafenib抗藥性之角色(2/3)

  Liao, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 嵌合抗原受體T細胞用於治療人類卵巢癌的免疫療法(2/3)

  Liu, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯 研究-乳癌細胞α9尼古丁受體/HER2複合體作為RNA奈米藥物治療HerceptinR抗藥 性之機制探討(1/3)

  Ho, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 組織胺甲基化轉換酵素(HNMT)輔助臨床醫師鑑別乳癌病患作為Herceptin療效評估之新穎分子標記(2/3)

  Ho, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 噬菌體展現技術製備之辨識蛇毒蛋白的雞源單鏈抗體之分析與人源化研究

  Yang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探查Pearson氏症候群的基因診斷與在患者衍生細胞上的施行清除粒線體DNA缺失的可行性

  Kao, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討ARE結合蛋白質與選擇性聚腺甘酸化作用在人類大腸直腸癌上所扮演的角色(3/3)

  Liang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• ETFDH突變於阿茲海默症之類澱粉前驅蛋白生成和細胞焦亡扮演的角色

  Kao, S.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• G蛋白偶聯雌激素受體在EGFR突變之肺腺癌細胞中扮演的角色

  Kao, S.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以單點基因編輯(single base editing)作為KRAS基因突變校正之抗癌治療研究

  Lee, C.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新神經與疼痛相關蛋白抗體開發-抗酸敏感離子通道3蛋白的抗體製備與定性

  Yang, Y.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以新穎mito-FD-CRISPR/Cas9系統開發粒線體基因編輯模式

  Lee, C.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 動物冠狀病毒抗體開發-抗豬流行性下痢病毒蛋白的抗體製備與定性

  Yang, Y.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 產學合作計畫－全基因組定序用於鑑別結核桿菌抗藥性基因試劑組之開 發計畫

  Lin, J.

  6/1/20 → 6/30/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新聘教師研究補助

  Chiu, J.

  6/1/20 → 5/31/22

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 紫膜光電生物晶片於血流病原菌快速檢測應用之探討(2)

  Wu, H.

  1/1/20 → 12/31/20

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Impacts of the Electron Transfer Flavoprotein Dehydrogenase Mutation on in Vitro Human Skeletal Muscle Plasticity

  Kao, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Emerging Impact of Mbnl1-Celf1 Regulatory Circuit Involved in the Development of White Adipocyte, Inducible Brown Adipocytes, and Classical Brown Adipocyte through Post-Transcriptional Regulation.

  Lin, J.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Roles of Npc2 Mediated Free Cholesterol Homeostasis in the Sorafenib-Resistant Hepatocellular Carcinoma( I )(1/3)

  Liao, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Targeting Ovarian Cancers with Chimeric Antigens Receptor (Cars) T-Cells Mediated Immunotherapy(1/3)

  Liu, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Job Mobility and Its Determinants among Medical Technology Undergraduates: Educational and Managerial Perspectives

  Liang, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Genetic and Cellular Factors in Women with Endometriosis(3/3)

  Tzeng, C. & Kao, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of the Roles of Au-Rich Element (Are)-Binding Proteins and Alternative Polyadenylation on the Tumorigenesis of Human Colorectal Cancer(2/3)

  Liang, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 人參莖、葉萃取物對阿茲海默症模型小鼠的療效評估

  Lin, Y.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以NIADS優化TNBC藥物篩檢平台並以基因編輯技術探討IL6R及IL7R在乳癌轉移所扮演的角色

  Lee, C.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抗組織胺藥物ketotifen抑制肝癌細胞生長之機制探討

  Liang, Y.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 腸病毒與宿主間的相互作用對病毒複製複合體形成及病毒複製之作用機轉(3/3)

  Lin, J.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Impact of Electron-Transfer-Flavoprotein Dehydrogenase Mutation on Bioenergetic Metabolism and Muscular Differentiation in Vitro

  Kao, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Multiple Acyl Coenzyme A Dehydrogenase Deficiency 100%
  • Electron-Transferring Flavoproteins 89%
  • Mutation 24%
  • Energy Metabolism 19%
  • Fatty Acids 18%