School of Medical Laboratory Science and Biotechnology

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2020 2021 2022 2023

• 8 Active
• 170 Finished

Projects per year

Search results

• Finished

  Targeting Cancer Cell’s Metabolism for Treatment of Human Malignant Glioma

  Lee, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glioma 100%
  • Anoikis 28%
  • Fenofibrate 26%
  • Thioctic Acid 26%
  • Lipids 25%

• Development of Novel Therapeutic Agents for Breast Cancer through Targeting Nicotinic Acetylcholine Receptors.

  Wu, C., Ho, Y. & Lee, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Resistance 100%
  • Nicotine 97%
  • Acute Toxicity 95%
  • Acetylcholine 85%
  • Drug 83%

• Crystal Structures and Functional Studies of Novel Glycosyltransferases from Staphylococcus aureus

  Liu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycosyltransferases 100%
  • Staphylococcus aureus 64%
  • Fibrin 30%
  • Cathepsin G 22%
  • Minisatellite Repeats 19%

• Study of C3H-Type Zinc-Finger Proteins on the Down-Regulation of Ubiquitination-Mediated Activation of Signal Transduction

  Liang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ubiquitin 100%
  • Ubiquitination 71%
  • Lysine 32%
  • Zinc Fingers 28%
  • Signal Transduction 25%

• Investigate the Biological and Prognostic Association of Annexin A2 in Nasopharyngeal Carcinoma

  Chen, C. & Lee, F.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Annexin A2 100%
  • Nasopharyngeal Carcinoma 85%
  • Annexins 40%
  • DC-specific ICAM-3 grabbing nonintegrin 12%
  • Radiotherapy 10%

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C. & Ho, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Trastuzumab 88%
  • Neoplastic Stem Cells 39%
  • Drug Resistance 27%
  • Luciferases 20%

• 台灣小葉葡萄抽取物改善高血糖之體內與體外研究

  Liang, Y.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 鋅指蛋白質負向調控生長訊息分子活性之研究

  Liang, Y.

  5/1/15 → 4/30/16

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 探討Annexin A2 在鼻咽癌的致癌功能與臨床應用

  Chen, C.

  3/1/15 → 2/29/16

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 產學合作開發嶄新抗體藥物之平台（3/3）

  Yang, Y.

  2/1/15 → 1/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Host Factors Affecting the Pathogenesis of Enterovirus 71 in Neuron and Non-Returnable Cells

  Lin, J.

  12/1/14 → 11/30/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Enterovirus 100%
  • Enterovirus Infections 87%
  • Tropism 44%
  • Small Interfering RNA 31%
  • Taiwan 24%

• Novel Strategies to Target Long-Lived Plasma Cells for Treating Hemophilia a Inhibitors

  Liu, C.

  9/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Plasma Cells 100%
  • Hemophilia A 70%
  • Stromal Cells 37%
  • Antibody Formation 33%
  • plerixafor octahydrochloride 18%

• Exploration of RBM4-Regulated Splicing Events in Differentiating Adipocytes by Using Next-Generation Sequencing

  Lin, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • brown adipose tissue 100%
  • insulin receptors 70%
  • adipocytes 54%
  • adipose tissue 50%
  • adipogenesis 45%

• Dysregulation of Huntingtin-Associated Protein-Mediated Calcium Trafficking in Neurodegenerative Diseases

  Lin, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Proto-Oncogene Proteins c-bcr 100%
  • Proteins 89%
  • Huntingtin Protein 71%
  • Neurodegenerative Diseases 63%
  • Kinesin 62%

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Trastuzumab 88%
  • Neoplastic Stem Cells 39%
  • Drug Resistance 27%
  • Luciferases 20%

• Investigation on the Suppressive Mechanisms of Novel Anti-Glypican3 Antibody Drugs

  Yang, Y.

  8/1/14 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glypicans 100%
  • Hepatocellular Carcinoma 20%
  • Antibodies 18%
  • Single-Chain Antibodies 10%
  • Heparan Sulfate Proteoglycans 10%

• https://www.grb.gov.tw/search/planDetail?id=8356932&docId=447412

  Lin, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Malondialdehyde 100%
  • Synovial Fluid 29%
  • Proteins 28%
  • Autoantibodies 17%
  • Rheumatoid Arthritis 15%

• 探討HIV-1反轉錄酉每與新穎先導藥物之複合體結構以利優化作為抗HIV候選藥物

  Liu, C.

  8/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Roles of Novel CCCH Zinc Finger Genes on the Regulation of Cell Proliferation and Inflammation

  Liang, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pyroptosis 100%
  • Apoptosis 69%
  • Genes 65%
  • Inflammasomes 60%
  • Cell Proliferation 58%

• Study the Therapeutic Role of Niemann-Pick Type C2 Protein in Liver Cancer

  Liao, Y.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Liver Neoplasms 70%
  • Carcinogenesis 40%
  • Cholesterol 39%
  • Liver 36%

• 探討Annexin A2 在鼻咽癌致癌機轉與其在化療和放射治療的預後方針

  Chen, C.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 新穎鋅指蛋白MCPIP1誘導細胞凋亡之分子機制研究

  Liang, Y.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 神經細胞中漢丁頓關聯蛋白緩解乙型類澱粉引起的神經退化之機制

  Lin, Y.

  6/1/14 → 12/31/15

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 利用高解析液相串連質譜儀鑑定非小細胞性肺癌腫瘤組織與血漿檢體中多種蛋白水解酶抑制蛋白之轉譯後修飾及其應用於肺癌特異性生物標誌開發之研究

  Lin, J.

  6/1/14 → 5/31/15

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 葉下珠活性成分抗發炎與保護血管內皮細胞評估

  Liang, Y.

  5/1/14 → 4/30/15

  Project: C - Project of Alliance › n - Yuan's General Hospital

• Development of Novel Therapeutic Agents for Breast Cancer through Targeting Nicotinic Acetylcholine Receptors.

  Wu, C., Ho, Y. & Lee, C.

  5/1/14 → 7/30/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Resistance 100%
  • Nicotine 97%
  • Acute Toxicity 95%
  • Acetylcholine 85%
  • Drug 83%

• TMU102-AE1-B24

  Lin, J.

  1/1/14 → 12/31/14

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 利用體外藥物致敏性標的分子篩選結合抗大腸直腸癌藥物之Lipid-base奈米劑型開發

  Liu, J.

  1/1/14 → 12/31/14

  Project: A - Government Institution › c - Ministry of Health and Welfare

• TMU102-AE1-B17

  Liu, C.

  1/1/14 → 12/31/14

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• TMU102-AE1-B28

  Liu, C.

  1/1/14 → 2/28/15

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Dissolution rate improvement of active pharmaceutical ingredients using supercritical fluid technology

  Sheu, M. & Liu, J.

  1/1/14 → 12/31/14

  Project: C - Project of Alliance › j - National Taipei University of Technology

• Structural and Functional Studies on the Virulence Regulators SaeR/S in Staphylococcus aureus

  Liu, C.

  12/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Staphylococcus aureus 100%
  • virulence 52%
  • immune evasion 23%
  • sepsis (infection) 23%
  • histidine kinase 21%

• Investigation of Host Factors Affecting the Pathogenesis of Enterovirus 71 in Neuron and Non-Returnable Cells

  Lin, J.

  12/1/13 → 11/30/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Enterovirus 100%
  • Enterovirus Infections 87%
  • Tropism 44%
  • Small Interfering RNA 31%
  • Taiwan 24%

• Novel Strategies to Target Long-Lived Plasma Cells for Treating Hemophilia a Inhibitors

  Liu, C.

  9/1/13 → 8/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Emerging Role That Splicing Factor Plays in the Adipose Development

  Lin, J.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • brown adipose tissue 100%
  • adipose tissue 84%
  • insulin receptors 78%
  • adipogenesis 75%
  • energy 49%

• Huntingtin-Associated Protein-Regulated Biomarkers in Neurodegenerative Diseases

  Lin, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Proteins 100%
  • Proto-Oncogene Proteins c-bcr 55%
  • Neurodegenerative Diseases 47%
  • Microtubules 39%
  • Calcium 37%

• Functional Characterization of Niemann-Pick Type C2 Protein in Hepatocellular Carcinoma

  Liao, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Liver Neoplasms 46%
  • Cholesterol 45%
  • Mitogen-Activated Protein Kinase 1 34%
  • Liver 32%

• Study of Anti-RRM-2 Antibody Drug Generation and Their Inhibitory Mechanisms

  Yang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antibodies 100%
  • Single-Chain Antibodies 93%
  • Anti-Idiotypic Antibodies 60%
  • Diphosphates 47%
  • human RRM2B protein 46%

• The Roles of Novel CCCH Zinc Finger Genes on the Regulation of Cell Proliferation and Inflammation

  Liang, Y.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pyroptosis 100%
  • Apoptosis 69%
  • Genes 65%
  • Inflammasomes 60%
  • Cell Proliferation 58%

• Development of Novel Therapeutic Agents for Herceptin Resistance Breast Cancer Cells through Targeting Nicotinic Acetylcholine Receptors

  Lee, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• 晶體性關節炎侵蝕骨頭(蝕骨細胞分化)的分子機制

  Liang, Y.

  6/1/13 → 5/31/14

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 鼻咽癌細胞Annexin A2誘導樹突狀細胞免疫抑制反應

  Chen, C.

  5/1/13 → 7/31/14

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• Functional Characterization of Niemann-Pick Type C2 Protein in Hepatocellular Carcinoma

  Liao, Y.

  1/1/13 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Liver Neoplasms 46%
  • Cholesterol 45%
  • Mitogen-Activated Protein Kinase 1 34%
  • Liver 32%

• TMU101-AE1-B29

  Liao, Y.

  1/1/13 → 12/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Integral and innovative researches of new biodegradable nanoporous complex applied on nasal packing materials

  Liu, J. & Lee, F.

  1/1/13 → 12/31/13

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Haemostatic 100%
  • Methyl Cellulose 53%
  • Chitosan 32%
  • Collagen 22%
  • Freeze Drying 16%

• Study of Anti-Αlpha-Enolase I Antibodies on Cancers and Their Potential Applications

  Yang, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Phosphopyruvate Hydratase 100%
  • Anti-Idiotypic Antibodies 22%
  • Antibodies 17%
  • Single-Chain Antibodies 13%
  • Neoplasms 10%

• Translational Genomic Approaches in Endometriosis

  Tzeng, C., Kao, S., Huang, Y., Yang, W., Yang, W., Yeh, C., Li, Y. & Shen, S.

  8/1/12 → 10/31/13

  Project: B - Project of TMU › i - Other (Funded by TMU)

  • endometrium 100%
  • microRNA 90%
  • stem cells 61%
  • cell adhesion molecules 54%
  • metastasis 35%

• The Pathogenic Role of Posttranslational Modification of Plasma N-Linked Glycoprotein to Rheumatoid Arthritis Combined Sjogren$S Syndrome Was Investigated

  Lin, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sjogren's Syndrome 100%
  • Rheumatoid Arthritis 73%
  • Post Translational Protein Processing 62%
  • Blood Proteins 19%
  • Proteins 14%

• The Roles of Novel CCCH Zinc Finger Genes on the Regulation of Cell Proliferation and Inflammation

  Liang, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Pyroptosis 100%
  • Apoptosis 69%
  • Genes 65%
  • Inflammasomes 60%
  • Cell Proliferation 58%

• Huntingtin-Associated Protein Related Biomarkers in Neural Survival

  Lin, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Huntingtin Protein 100%
  • Mouse Hap1 protein 77%
  • Microtubules 50%
  • Biomarkers 33%
  • Proteins 25%