School of Medical Laboratory Science and Biotechnology

Projects

Projects per year 2010 2012 2013 2014 2015 2016 2017 2018 2020 2021 2022 2023

• 8 Active
• 170 Finished

Projects per year

Search results

• Finished

  Study of the Roles of Au-Rich Element (Are)-Binding Proteins and Alternative Polyadenylation on the Tumorigenesis of Human Colorectal Cancer(1/3)

  Liang, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Therapeutic Role of Niemann-Pick Type C2 Protein in the Inhibition of Hscs Activation and Liver Fibrosis Treatment

  Liao, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Liver Cirrhosis 100%
  • Cholesterol 39%
  • Becaplermin 35%
  • Fibrosis 13%
  • Fetal Proteins 12%

• Carbamylation Modification of Novel Synovial Fluid and Serum Proteins and Its Role of Anti-Carbanylated Protein Autoantibodies in the Clinic Association of Rheumatoid Arthritis Was Investigated

  Lin, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Rheumatoid Arthritis 100%
  • Protein Carbamylation 74%
  • Synovial Fluid 68%
  • Proteins 44%
  • Autoantibodies 41%

• Investigation of the Curcumin- and Berberine-Mediated Post-Transcriptional Regulation on Ehnancing Brown Adipogenesis

  Lin, J.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • adipogenesis 100%
  • microRNA 84%
  • berberine 64%
  • curcumin 59%
  • amino acid motifs 59%

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer(3/3)

  Liu, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• 腸病毒A71型3A蛋白質與Rab7A蛋白質的交互作用對病毒複製及晚期自噬作用之影響

  Lin, J.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討電脈衝刺激強化肌肉細胞的能量代謝及降低肌肉細胞萎縮與壞死的分子機制

  Kao, S.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the mechanisms of novel benzimidazole derivative in the sorafenib-resistance liver cancer cell

  Liao, Y.

  7/1/18 → 2/28/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 紫膜光電生物晶片於血流病原菌快速檢測應用之探討

  Wu, H.

  1/1/18 → 12/31/18

  Project: C - Project of Alliance › m - National Taiwan University of Science and Technology

• Human Anti-Citrullinated Inter-Alpha-Trypsin Inhibitor Heavy Chain H3 Peptide Antibody Elisa Kit : in Vi Tro Diagnostics Kit of Autoimmune Rheumatic Diseases Examination

  Lin, C.

  11/1/17 → 10/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Rheumatoid Arthritis 100%
  • Peptides 38%
  • inter-alpha-inhibitor 32%
  • Anti-Citrullinated Protein Antibodies 27%
  • Autoantibodies 27%

• Protective Effects Ofα-Lipoic Acid against Renal Fibrosis in Diabetic Mice

  Lee, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Thioctic Acid 100%
  • Kidney 53%
  • Lysine 48%
  • Osteopontin 44%
  • Diabetic Nephropathies 39%

• Study the Roles of Npc2 in the Regulation of Hepatic Stellate Cells Activation and Liver Fibrosis

  Liao, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Liver Cirrhosis 82%
  • Cholesterol 41%
  • Down-Regulation 17%
  • Fetal Proteins 11%
  • Becaplermin 10%

• Investigation of Long Non-Coding Rna on the Tumorigenesis in Human Colorectal Cancer

  Liang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Long Noncoding RNA 100%
  • MicroRNAs 26%
  • Colorectal Neoplasms 19%
  • Single Nucleotide Polymorphism 17%
  • Nestin 13%

• Impact of Electron-Transfer-Flavoprotein Dehydrogenase Mutation on Bioenergetic Metabolism and Muscular Differentiation in Vitro

  Kao, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Multiple Acyl Coenzyme A Dehydrogenase Deficiency 100%
  • Electron-Transferring Flavoproteins 89%
  • Mutation 24%
  • Energy Metabolism 19%
  • Fatty Acids 18%

• Mechanisms by Which Enterovirus-Host Interactions Form Viral Replication Organelles and Regulate Viral Replication

  Lin, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Organelles 100%
  • Enterovirus 53%
  • Intracellular Membranes 29%
  • Host Microbial Interactions 29%
  • Membranes 27%

• Investigation for the Molecular Mechanism Involved in the Expression and Impact of Alternatively-Spliced Srsf3 and Map4k4 Variants on Brown Adipogenesis

  Lin, J.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • serine 100%
  • arginine 95%
  • adipogenesis 82%
  • brown adipose tissue 72%
  • alternative splicing 55%

• Occupation Choices, Work Characteristics, and Career Success of Medical Technology Undergraduates from Gender and Generational Perspectives (K01)

  Liang, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • medical technology 100%
  • bachelor 44%
  • graduate 29%
  • gender role 22%
  • Taiwan 19%

• Crystal Structures and Functional Studies of Novel Glycosyltransferases from Staphylococcus Aureus

  Liu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycosyltransferases 100%
  • Staphylococcus aureus 64%
  • Fibrin 30%
  • Cathepsin G 22%
  • Minisatellite Repeats 19%

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer

  Liu, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• 以阿茲海默症模型細胞篩選與評估醣苷神經鞘醯胺衍生物之藥效

  Lin, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以基因剪輯技術(CRISPR/Cas9)應用於費城染色體為標靶之慢性骨髓性白血病治療

  Lee, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討新型benzimidazole衍生物抑制肝癌抗藥性細胞生長的角色

  Liao, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 苦瓜葉抽取物對於腸胃道免疫提昇與降低畜產養殖業抗生素使用模式評估研究

  Liu, J.

  7/1/17 → 12/31/17

  Project: A - Government Institution › e - Council of Agriculture

• EBP1蛋白質對於細胞及病毒IRES的影響及其作用機轉

  Lin, J.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• MCPIPs鋅指蛋白家族在人類大腸直腸癌組織的表現及調控Akt訊息傳遞路徑之研究

  Liang, Y.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 抗免疫監測點抑制因子PD1 與PDL1的嵌合抗原受體修飾性γδ-T細胞用於治療卵巢癌療效之探討

  Liu, C.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討鼻咽癌的標的治療奈米分子雙抗體或配合化學治療的特性

  Chen, C.

  3/1/17 → 2/28/18

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 以白色念珠菌 alpha-enolase 為目標的單株抗體的人源化與其可能的應用

  Yang, Y.

  2/1/17 → 1/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanisms by Which Enterovirus-Host Interactions Form Viral Replication Organelles and Regulate Viral Replication

  Lin, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Organelles 100%
  • Enterovirus 53%
  • Intracellular Membranes 29%
  • Host Microbial Interactions 29%
  • Membranes 27%

• Investigate Pathogenic Role of Rheumatoid Arthritis, Sjogren$S Syndrome, Systemic Lupus Erythematosus and Its Combined Syndromes from Post-Translational Modification of Serum Proteins: Study of Malondialdehyde Modification

  Lin, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Malondialdehyde 100%
  • Sjogren's Syndrome 94%
  • Systemic Lupus Erythematosus 54%
  • Autoantibodies 23%
  • Peptides 20%

• 研究NPC2蛋白抑制肝細胞增生與癌化的機制(3/3)

  Liao, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Liver Neoplasms 52%
  • Carcinogenesis 40%
  • Cholesterol 39%
  • Liver 36%

• Impact of Electron-Transfer-Flavoprotein Dehydrogenase Mutation on Bioenergetic Metabolism and Muscular Differentiation in Vitro

  Kao, S.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Multiple Acyl Coenzyme A Dehydrogenase Deficiency 100%
  • Electron-Transferring Flavoproteins 89%
  • Mutation 24%
  • Energy Metabolism 19%
  • Fatty Acids 18%

• 亨丁頓關聯蛋白與阿伯爾森幫手整合位點蛋白的交互作用在乙型類澱粉引起的神經退化中之角色

  Lin, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Engineering Chimeric Antigen Receptor T-Cells against Immune Checkpoint Inhibitor Pd1 and Pd-L1 for Treating Pancreatic Cancer

  Liu, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chimeric Antigen Receptors 100%
  • T-Lymphocytes 34%
  • Pancreatic Neoplasms 29%
  • Neoplasms 17%
  • atezolizumab 9%

• Crystal Structures and Functional Studies of Novel Glycosyltransferases from Staphylococcus aureus(2/3)

  Liu, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycosyltransferases 100%
  • Staphylococcus aureus 64%
  • Fibrin 30%
  • Cathepsin G 22%
  • Minisatellite Repeats 19%

• Exploration and Investigation of Brown Adipogenesis-Associated Alternative Splicing Network by Transcriptome Analyses

  Lin, J.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • brown adipose tissue 100%
  • adipogenesis 64%
  • alternative splicing 41%
  • brown adipocytes 34%
  • obesity 25%

• Investigation of K63-Linked Deubiquitination Effects of Mcpip Family Members and Their Genetic Profiles through Tcga Data Analysis

  Liang, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • TNF Receptor-Associated Factor 2 100%
  • Ubiquitin 82%
  • Ubiquitination 71%
  • Genetic Profile 63%
  • Signal Transduction 38%

• 蝦紅素臨床應用劑型開發

  Liu, J.

  6/1/16 → 5/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討ANXA2/PD-L1雙抗體免疫療法在鼻咽癌上的協同效果

  Chen, C.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• Investigation of Host Factors Affecting the Pathogenesis of Enterovirus 71 in Neuron and Non-Returnable Cells

  Lin, J.

  12/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Enterovirus 100%
  • Enterovirus Infections 87%
  • Tropism 44%
  • Small Interfering RNA 31%
  • Taiwan 24%

• Crystal Structures and Functional Studies of Novel Glycosyltransferases from Staphylococcus aureus

  Liu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glycosyltransferases 100%
  • Staphylococcus aureus 64%
  • Fibrin 30%
  • Cathepsin G 22%
  • Minisatellite Repeats 19%

• Targeting Cancer Cell’s Metabolism for Treatment of Human Malignant Glioma

  Lee, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glioma 100%
  • Anoikis 28%
  • Fenofibrate 26%
  • Thioctic Acid 26%
  • Lipids 25%

• Development of Novel Colchicine Derivative for Anticancer

  Liu, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colchicine 100%
  • Lethal Dose 14%
  • Drug 10%
  • Safety 8%
  • Food 6%

• Multivariate Bioinformatics Analysis of Taiwanese Cancer RNA-Seq Data to Study Human Endogenous Retroviruses as Carcinogens

  Lee, Y. G. & Lin, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Endogenous Retroviruses 100%
  • Neoplasms 40%
  • RNA-Seq 36%
  • Genome 21%
  • Computational Biology 19%

• Study the Therapeutic Role of Niemann-Pick Type C2 Protein in Liver Cancer

  Liao, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hepatocellular Carcinoma 100%
  • Liver Neoplasms 70%
  • Carcinogenesis 40%
  • Cholesterol 39%
  • Liver 36%

• Study of C3H-Type Zinc-Finger Proteins on the Down-Regulation of Ubiquitination-Mediated Activation of Signal Transduction

  Liang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ubiquitin 100%
  • Ubiquitination 71%
  • Lysine 32%
  • Zinc Fingers 28%
  • Signal Transduction 25%

• Study on the Effect of the Recombinant OmpA Protein Fragments Protect Mice from Death Caused by E. coli Induced Bacteremia

  Wu, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • OMPA outer membrane proteins 100%
  • Escherichia coli Infections 70%
  • Escherichia coli 29%
  • Proteins 17%
  • Leukocytes 16%

• Huntingtin-Associated Protein-Mediated Vesicular Trafficking Biomarkers in Neurodegenerative Diseases

  Lin, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Alzheimer Disease 100%
  • Microtubules 83%
  • Neurodegenerative Diseases 74%
  • Biomarkers 69%
  • Huntingtin Protein 62%

• Molecular Ivestigation of the Electron Transfer Flavoprotein Dehydrogenase Mutation Induced Mitochondrial Dysfunction and Metabolic Defects

  Kao, S. & Hsu, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • acyl-CoA dehydrogenase 100%
  • flavoproteins 97%
  • electron transfer 79%
  • droplets 39%
  • myoblasts 31%

• The Effect of Long Acting GnRH Agonist Treatment on Mitochondrial Function

  Tzeng, C., Hsieh, R. & Kao, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • hormone agonists 100%
  • mitochondria 91%
  • pathophysiology 42%
  • granulosa cells 38%
  • agonists 32%