Research Center of Thoracic Medicine-TB

Research Output 1995 2020

2020

Comparison of the predictive outcomes for anti-tuberculosis drug-induced hepatotoxicity by different machine learning techniques

Lai, N. H., Shen, W. C., Lee, C. N., Chang, J. C., Hsu, M. C., Kuo, L. N., Yu, M. C. & Chen, H. Y., May 2020, In : Computer Methods and Programs in Biomedicine. 188, 105307.

Research output: Contribution to journalArticle

Learning systems
Tuberculosis
Neural networks
ROC Curve
Support vector machines
2019

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Shen, T. J., Jhan, M. K., Kao, J. C., Ho, M. R., Tsai, T. T., Tseng, P-C., Wang, Y. T. & Lin, C-F., 2019, In : Journal of Visualized Experiments.

Research output: Contribution to journalArticle

Viral Encephalitis
Dengue Virus
Viruses
Severe Dengue
Arboviruses
Social Welfare
Taiwan
Pharmacists
Pharmaceutical Services
Community Pharmacy Services
37 Citations (Scopus)

A trial of a shorter regimen for rifampin-resistant tuberculosis

Nunn, A. J., Phillips, P. P. J., Meredith, S. K., Chiang, C. Y., Conradie, F., Dalai, D., Van Deun, A., Dat, P. T. O., Lan, N., Master, I., Mebrahtu, T., Meressa, D., Moodliar, R., Ngubane, N., Sanders, K., Squire, S. B., Torrea, G., Tsogt, B. & Rusen, I. D., Mar 28 2019, In : New England Journal of Medicine. 380, 13, p. 1201-1213 13 p.

Research output: Contribution to journalArticle

Fluoroquinolones
Aminoglycosides
Rifampin
Tuberculosis
United States Agency for International Development
1 Citation (Scopus)
Open Access
Calciphylaxis
Trichosporon
Necrotizing Fasciitis
Infection
Therapeutics
2 Citations (Scopus)

Calling time on asthma deaths in tropical regions—how much longer must people wait for essential medicines?

Asher, I., Bissell, K., Chiang, C. Y., El Sony, A., Ellwood, P., García-Marcos, L., Marks, G. B., Mortimer, K., Pearce, N. & Strachan, D., Jan 1 2019, In : The Lancet Respiratory Medicine. 7, 1, p. 13-15 3 p.

Research output: Contribution to journalComment/debate

Asthma
1 Citation (Scopus)

Circulating sphingosine-1-phosphate as a prognostic biomarker for community-acquired pneumonia

Hsu, S. C., Chang, J. H., Hsu, Y. P., Bai, K. J., Huang, S. K. & Hsu, C. W., May 1 2019, In : PLoS ONE. 14, 5, e0216963.

Research output: Contribution to journalArticle

Open Access
sphingosine
Biomarkers
pneumonia
biomarkers
Pneumonia

Essential medicines at the national level: The global asthma network’s essential asthma medicines survey 2014

Global Asthma Network Study Group, Bissell, K., Ellwood, P., Ellwood, E., Chiang, C. Y., Marks, G. B., El Sony, A., Asher, I., Billo, N. & Perrin, C., Feb 1 2019, In : International Journal of Environmental Research and Public Health. 16, 4, 605.

Research output: Contribution to journalArticle

Open Access
Asthma
Adrenal Cortex Hormones
Surveys and Questionnaires
Albuterol
Cross-Sectional Studies
Ionizing radiation
Ionizing Radiation
Interferons
Cytotoxicity
STAT1 Transcription Factor
4 Citations (Scopus)

Functional neutralization of anti-IFN-γ autoantibody in patients with nontuberculous mycobacteria infection

Krisnawati, D. I., Liu, Y. C., Lee, Y. J., Wang, Y. T., Chen, C. L., Tseng, P. C. & Lin, C. F., Apr 5 2019, In : Scientific Reports. 9, 1, p. 5682 5682.

Research output: Contribution to journalArticle

Open Access
Nontuberculous Mycobacterium Infections
Autoantibodies
Interferons
Serum
Chemokines

Impact of metformin use among tuberculosis close contacts with diabetes mellitus in a nationwide cohort study

Lee, M. C., Lee, C. H., Lee, M. R., Wang, J. Y. & Chen, S. M., Nov 6 2019, In : BMC Infectious Diseases. 19, 1, 936.

Research output: Contribution to journalArticle

Open Access
Metformin
Diabetes Mellitus
Tuberculosis
Cohort Studies
Insulin

Impact of universal drug susceptibility testing and effective management of multidrug-resistant tuberculosis in Taiwan

Lee, P. H., Chan, P. C., Peng, Y. T., Chu, P. W., Wu, M. H., Jou, R., Yu, M. C., Lin, C. J., Huang, Y. W., Chien, S. T., Lee, J. J. & Chiang, C. Y., Apr 1 2019, In : PLoS One. 14, 4, e0214792.

Research output: Contribution to journalArticle

Open Access
Multidrug-Resistant Tuberculosis
Taiwan
tuberculosis
drugs
Testing

Microglial activation and inflammation caused by traffic-related particulate matter

Bai, K. J., Chuang, K. J., Chen, C. L., Jhan, M. K., Hsiao, T. C., Cheng, T. J., Chang, L. T., Chang, T. Y. & Chuang, H. C., Sep 25 2019, In : Chemico-Biological Interactions. 311, 108762.

Research output: Contribution to journalArticle

Soot
Vehicle Emissions
Particulate Matter
Chemical activation
Inflammation
1 Citation (Scopus)

Streptolysin S induces mitochondrial damage and macrophage death through inhibiting degradation of glycogen synthase kinase-3β in Streptococcus pyogenes infection

Tsao, N., Kuo, C. F., Cheng, M. H., Lin, W. C., Lin, C. F. & Lin, Y. S., Dec 1 2019, In : Scientific Reports. 9, 1, 5371.

Research output: Contribution to journalArticle

Glycogen Synthase Kinase 3
Streptococcus pyogenes
Streptococcus
Macrophages
Infection
2 Citations (Scopus)

Tolerability of rifapentine-based regimens in latent tuberculosis infection treatment in the elderly

Chan, P. C., Lee, P. H., Lu, M. J., Huang, Y. C., Feng, T. Y., Chen, W. W., Lee, C. C., Huang, Y. F. & Chiang, C. Y., Mar 1 2019, In : The European respiratory journal. 53, 3

Research output: Contribution to journalLetter

Open Access
rifapentine
Latent Tuberculosis
Therapeutics
2 Citations (Scopus)

Treatment outcomes for multidrug-resistant tuberculosis in Eastern Taiwan

Lin, C. B., Sun, H. C., Chiang, C. Y., Wu, C. W., Chou, H. W., Tang, T. Q. & Lee, J. J., Jan 1 2019, In : Tzu Chi Medical Journal. 31, 1, p. 35-39 5 p.

Research output: Contribution to journalArticle

Open Access
Multidrug-Resistant Tuberculosis
Taiwan
Therapeutics
Quality of Health Care
Lost to Follow-Up
2018
2 Citations (Scopus)

Acute biliary events during anti-tuberculosis treatment: Hospital case series and a nationwide cohort study

Chang, L. Y., Lee, C. H., Chang, C. H., Lee, M. C., Lee, M. R., Wang, J. Y. & Lee, L. N., Feb 1 2018, In : BMC Infectious Diseases. 18, 1, 64.

Research output: Contribution to journalArticle

Chronic Disease Hospitals
Tuberculosis
Cohort Studies
Pulmonary Tuberculosis
Therapeutics
5 Citations (Scopus)

Anti-TNF-α restricts dengue virus-induced neuropathy

Jhan, M. K., Huangfu, W. C., Chen, Y. F., Kao, J. C., Tsai, T. T., Ho, M. R., Shen, T. J., Tseng, P. C., Wang, Y. T. & Lin, C. F., Jan 1 2018, (Accepted/In press) In : Journal of Leukocyte Biology.

Research output: Contribution to journalArticle

Dengue Virus
Encephalitis
Virus Diseases
Dengue
Neurons
1 Citation (Scopus)

Autophagy regulates vinorelbine sensitivity due to continued Keap1-mediated ROS generation in lung adenocarcinoma cells

Wu, Y-W., Lin, C-F., Lin, Y-S., Su, W-C. & Chiu, W-H., 2018, In : Cell Death Discovery. 5, p. 33

Research output: Contribution to journalArticle

Autophagy
Antioxidant Response Elements
Apoptosis
Drug Therapy
Physiological Stress
11 Citations (Scopus)
Protein-Tyrosine Kinases
Disease-Free Survival
Cytotoxic T-Lymphocytes
Bevacizumab
Myeloid-Derived Suppressor Cells
1 Citation (Scopus)

Building the evidence base for shortened MDR-TB treatment regimens

Rusen, I. D. & Chiang, C. Y., Jan 1 2018, In : International Journal of Tuberculosis and Lung Disease. 22, 1, 1 p.

Research output: Contribution to journalEditorial

2 Citations (Scopus)

Characterization of chicken-derived single chain antibody fragments against venom of Naja naja atra

Lee, C. H., Leu, S. J., Lee, Y. C., Liu, C. I., Lin, L. T., Mwale, P. F., Chiang, J. R., Tsai, B. Y., Chen, C. C., Hung, C. S. & Yang, Y. Y., Oct 1 2018, In : Toxins. 10, 10, 383.

Research output: Contribution to journalArticle

Cobra Venoms
Elapidae
Single-Chain Antibodies
Immunoglobulin Fragments
Venoms
5 Citations (Scopus)

Comparative effectiveness of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in chemoprevention of hepatocellular carcinoma: A nationwide high-risk cohort study

Ho, C. M., Lee, C. H., Lee, M. C., Zhang, J. F., Wang, J. Y., Hu, R. H. & Lee, P. H., Apr 10 2018, In : BMC Cancer. 18, 1, 401.

Research output: Contribution to journalArticle

Angiotensin Receptor Antagonists
Chemoprevention
Angiotensin-Converting Enzyme Inhibitors
Hepatocellular Carcinoma
Hepacivirus
Technology
Adenocarcinoma of lung
Myeloid-Derived Suppressor Cells
2 Citations (Scopus)

Effects of diesel exhaust particles on the expression of tau and autophagy proteins in human neuroblastoma cells

Bai, K. J., Chuang, K. J., Wu, S. M., Chang, L. T., Chang, T. Y., Ho, K. F. & Chuang, H. C., Sep 1 2018, In : Environmental Toxicology and Pharmacology. 62, p. 54-59 6 p.

Research output: Contribution to journalArticle

Vehicle Emissions
tau Proteins
Autophagy
Neuroblastoma
Soot
2 Citations (Scopus)
Histone Deacetylases
Autophagy
High Fat Diet
Nutrition
Streptozocin
4 Citations (Scopus)

Investigation into the pulmonary inflammopathology of exposure to nickel oxide nanoparticles in mice

Bai, K. J., Chuang, K. J., Chen, J. K., Hua, H. E., Shen, Y. L., Liao, W. N., Lee, C. H., Chen, K. Y., Lee, K. Y., Hsiao, T. C., Pan, C. H., Ho, K. F. & Chuang, H. C., Oct 1 2018, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 7, p. 2329-2339 11 p.

Research output: Contribution to journalArticle

Nickel oxide
Nanoparticles
Lung
Pneumonia
Tissue
9 Citations (Scopus)
metformin
Metformin
renal function
Medical problems
diabetes mellitus
3 Citations (Scopus)
Tubulin Modulators
G2 Phase Cell Cycle Checkpoints
Colorectal Neoplasms
Apoptosis
Growth
4 Citations (Scopus)

QTc and anti-tuberculosis drugs: A perfect storm or a tempest in a teacup? Review of evidence and a risk assessment

Monedero-Recuero, I., Hernando-Marrupe, L., Sánchez-Montalvá, A., Cox, V., Tommasi, M., Furin, J., Chiang, C. Y., Quelapio, M., Koura, K. G., Trébucq, A., Padanilam, X., Dravniece, G. & Piubello, A., Dec 1 2018, In : International Journal of Tuberculosis and Lung Disease. 22, 12, p. 1411-1421 11 p.

Research output: Contribution to journalReview article

Tuberculosis
Extensively Drug-Resistant Tuberculosis
Torsades de Pointes
Pharmaceutical Preparations
Cardiac Arrhythmias
5 Citations (Scopus)

S100A9+ MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: The role of RELB

Feng, P. H., Yu, C. T., Chen, K. Y., Luo, C. S., Wu, S. M., Liu, C. Y., Kuo, L. W., Chan, Y. F., Chen, T. T., Chang, C. C., Lee, C. N., Chuang, H. C., Lin, C. F., Han, C. L., Lee, W. H. & Lee, K. Y., Jan 26 2018, In : Oncotarget. 9, 7, p. 7631-7643 13 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Macrophages
Microarray Analysis
Blood Cells
Alveolar Macrophages
2 Citations (Scopus)

Should gatifloxacin be included in the model list of essential medicines?

Chiang, C-Y., Trébucq, A., Piubello, A., Rieder, H. L. & Van Deun, A., Feb 2018, In : European Respiratory Journal. 51, 2

Research output: Contribution to journalArticle

3 Citations (Scopus)

Should tobacco control intervention be implemented into tuberculosis control program?

Chiang, C. Y. & Bam, T. S., Jul 3 2018, In : Expert Review of Respiratory Medicine. 12, 7, p. 541-543 3 p.

Research output: Contribution to journalEditorial

Tobacco
Tuberculosis

Signaling of Macrophage Inflammatory Protein (MIP)-3β Facilitates Dengue Virus-Induced Microglial Cell Migration

Jhan, M-K., Shen, T-J., Tseng, P-C., Wang, Y-T. & Lin, C-F., Dec 1 2018, In : Viruses. 10, 12

Research output: Contribution to journalArticle

Macrophage Inflammatory Proteins
Dengue Virus
Cell Movement
Conditioned Culture Medium
JNK Mitogen-Activated Protein Kinases
8 Citations (Scopus)

The antiparasitic drug niclosamide inhibits dengue virus infection by interfering with endosomal acidification independent of mTOR

Kao, J. C., HuangFu, W. C., Tsai, T. T., Ho, M. R., Jhan, M. K., Shen, T. J., Tseng, P. C., Wang, Y. T. & Lin, C. F., Aug 1 2018, In : PLoS Neglected Tropical Diseases. 12, 8, e0006715.

Research output: Contribution to journalArticle

Niclosamide
Antiparasitic Agents
Dengue Virus
Virus Diseases
Sirolimus
1 Citation (Scopus)
Type 2 Diabetes Mellitus
chronic illness
Hypoglycemic Agents
drug
Taiwan
7 Citations (Scopus)

Treatment outcomes of multidrug-resistant tuberculosis in Taiwan: Tackling loss to follow-up

Yu, M. C., Chiang, C. Y., Lee, J. J., Chien, S. T., Lin, C. J., Lee, S. W., Lin, C. B., Yang, W. T., Wu, Y. H. & Huang, Y. W., Jul 2 2018, In : Clinical Infectious Diseases. 67, 2, p. 202-210 9 p.

Research output: Contribution to journalArticle

Multidrug-Resistant Tuberculosis
Taiwan
Odds Ratio
Confidence Intervals
Treatment Failure

Tuberculosis re-treatment after exclusion of rifampicin resistance

Chiang, C-Y. & Trébucq, A., Feb 2018, In : European Respiratory Journal. 51, 2

Research output: Contribution to journalArticle

1 Citation (Scopus)

Using modified information delivery to enhance the traditional pharmacy OSCE program at TMU – a pilot study

Lin, C. W., Chang, E. H., Clinciu, D. L., Peng, Y. T., Huang, W. C., Wu, C. C., Wu, J. C. & Li, Y. C., May 1 2018, In : Computer Methods and Programs in Biomedicine. 158, p. 147-152 6 p.

Research output: Contribution to journalArticle

Students
Education
Aptitude
Prescriptions
Curricula
2017
20 Citations (Scopus)
Antrodia
Taiwanofungus camphoratus
Ubiquinone
Neoplastic Stem Cells
ubiquinones
16 Citations (Scopus)

AR-12 suppresses dengue virus replication by down-regulation of PI3K/AKT and GRP78

Chen, H., Chen, C. C., Lin, Y. S., Chang, P. C., Lu, Z. Y., Lin, C. F., Chen, C. L. & Chang, C. P., Jun 1 2017, In : Antiviral Research. 142, p. 158-168 11 p.

Research output: Contribution to journalArticle

Dengue Virus
Virus Replication
Phosphatidylinositol 3-Kinases
Down-Regulation
Virus Diseases
3 Citations (Scopus)
Emergency rooms
Particulate Matter
asthma
Hospital Emergency Service
particulates
10 Citations (Scopus)

Blockade of dengue virus infection and viral cytotoxicity in neuronal cells in vitro and in vivo by targeting endocytic pathways

Ho, M. R., Tsai, T. T., Chen, C. L., Jhan, M. K., Tsai, C. C., Lee, Y. C., Chen, C. H. & Lin, C. F., Dec 1 2017, In : Scientific Reports. 7, 1, 7023.

Research output: Contribution to journalArticle

Dengue Virus
Virus Diseases
Clathrin
Vacuolar Proton-Translocating ATPases
Endocytosis
Enterobacter cloacae
Carbapenems
Klebsiella pneumoniae
Taiwan
Intensive Care Units
10 Citations (Scopus)

Dengue virus infection increases microglial cell migration

Jhan, M. K., Tsai, T. T., Chen, C. L., Tsai, C. C., Cheng, Y. L., Lee, Y. C., Ko, C. Y., Lin, Y. S., Chang, C. P., Lin, L. T. & Lin, C. F., Jan 1 2017, In : Scientific Reports. 7, 1, 91.

Research output: Contribution to journalArticle

Dengue Virus
Virus Diseases
Cell Movement
Clathrin
Viral RNA
2 Citations (Scopus)

Development and validation of a Chinese medication literacy measure

Yeh, Y. C., Lin, H. W., Chang, E. H., Huang, Y. M., Chen, Y. C., Wang, C. Y., Liu, J. W. & Ko, Y., 2017, In : Health Expectations.

Research output: Contribution to journalArticle

Literacy
Nonprescription Drugs
Health Literacy
Drug Prescriptions
Medication Errors
1 Citation (Scopus)
Mycobacterium kansasii
Sinus Histiocytosis
Mycobacterium Infections
Autoantibodies
Interferons
Taiwan
Pulmonary Tuberculosis
Dialysis
Tuberculosis
Therapeutics
31 Citations (Scopus)

Escape from IFN-γ-dependent immunosurveillance in tumorigenesis

Lin, C. F., Lin, C. M., Lee, K. Y., Wu, S. Y., Feng, P. H., Chen, K. Y., Chuang, H. C., Chen, C-L., Wang, Y. C., Tseng, P. C. & Tsai, T. T., Feb 1 2017, In : Journal of Biomedical Science. 24, 1, p. 1-9 9 p.

Research output: Contribution to journalReview article

Immunologic Monitoring
Interferons
Carcinogenesis
Cells
Immunosuppressive Agents