Research Center of Thoracic Medicine-Lung Cancer Group

Research Output 2003 2020

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2019
4 Citations (Scopus)

A double-virally-inactivated (Intercept–solvent/detergent) human platelet lysate for in vitro expansion of human mesenchymal stromal cells

Barro, L., Su, Y. T., Nebie, O., Wu, Y. W., Huang, Y. H., Koh, M. B. C., Knutson, F. & Burnouf, T., Jan 1 2019, In : Transfusion.

Research output: Contribution to journalArticle

Mesenchymal Stromal Cells
Detergents
Blood Platelets
Serum
In Vitro Techniques
3 Citations (Scopus)

Chloramphenicol induces autophagy and inhibits the hypoxia inducible factor-1 alpha pathway in non-small cell lung cancer cells

Hsu, H. L., Liao, P. L., Cheng, Y. W., Huang, S. H., Wu, C. H., Li, C. H. & Kang, J. J., Jan 1 2019, In : International Journal of Molecular Sciences. 20, 1, 157.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
hypoxia
Autophagy
Chloramphenicol
Non-Small Cell Lung Carcinoma
2 Citations (Scopus)
Pulmonary diseases
pneumonia
Air pollution
atmospheric pollution
confidence interval
1 Citation (Scopus)

DNMT3b/OCT4 expression confers sorafenib resistance and poor prognosis of hepatocellular carcinoma through IL-6/STAT3 regulation

Lai, S. C., Su, Y. T., Chi, C. C., Kuo, Y. C., Lee, K. F., Wu, Y. C., Lan, P. C., Yang, M. H., Chang, T. S. & Huang, Y. H., Nov 26 2019, In : Journal of Experimental and Clinical Cancer Research. 38, 1, 474.

Research output: Contribution to journalArticle

Open Access
Octamer Transcription Factors
Methyltransferases
Hepatocellular Carcinoma
Interleukin-6
DNA

Effects of PM2.5 on Skeletal Muscle Mass and Body Fat Mass of the Elderly in Taipei, Taiwan

Chen, C. H., Huang, L. Y., Lee, K. Y., Wu, C. D., Chiang, H. C., Chen, B. Y., Chin, W. S., Pan, S. C. & Guo, Y. L., Aug 1 2019, In : Scientific Reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Taiwan
Adipose Tissue
Body Composition
Skeletal Muscle
Air Pollution
1 Citation (Scopus)

Electrospun polylactic acid (PLLA) microtube array membrane (MTAM)-An advanced substrate for anticancer drug screening

Tseng, C. H., Huang, W. T., Chew, C. H., Lai, J. K., Tu, S. H., Wei, P. L., Lee, K. Y., Lai, G. M. & Chen, C. C., Feb 14 2019, In : Materials. 12, 4, 569.

Research output: Contribution to journalArticle

Open Access
Assays
Screening
Membranes
Cells
Acids
1 Citation (Scopus)

FOSB-PCDHB13 axis disrupts the microtubule network in non-small cell lung cancer

Ting, C. H., Lee, K. Y., Wu, S. M., Feng, P. H., Chan, Y. F., Chen, Y. C. & Chen, J. Y., Jan 1 2019, In : Cancers. 11, 1, 107.

Research output: Contribution to journalArticle

Open Access
Non-Small Cell Lung Carcinoma
Microtubules
Tilapia
Mortality
Chromatin Immunoprecipitation
Open Access
Spermatic Cord Torsion
Sperm Motility
Stem cells
Mesenchymal Stromal Cells
Metabolism
Haptoglobins
Chronic Obstructive Pulmonary Disease
Inflammation
Phenotype
Alveolar Epithelial Cells
2018
1 Citation (Scopus)

A machine learning texture model for classifying lung cancer subtypes using preliminary bronchoscopic findings

Feng, P. H., Lin, Y. T. & Lo, C. M., Jan 1 2018, (Accepted/In press) In : Medical Physics.

Research output: Contribution to journalArticle

Lung Neoplasms
Color
Bronchoscopy
ROC Curve
Squamous Cell Carcinoma
12 Citations (Scopus)

Association of PM2.5 with sleep-disordered breathing from a population-based study in Northern Taiwan urban areas

Shen, Y. L., Liu, W. T., Lee, K. Y., Chuang, H. C., Chen, H. W. & Chuang, K. J., Feb 1 2018, In : Environmental Pollution. 233, p. 109-113 5 p.

Research output: Contribution to journalArticle

Air Pollution
Sleep Apnea Syndromes
Apnea
Air pollution
Taiwan
6 Citations (Scopus)

Association of ultrafine particles with cardiopulmonary health among adult subjects in the urban areas of northern Taiwan

Liu, J. Y., Hsiao, T. C., Lee, K. Y., Chuang, H. C., Cheng, T. J. & Chuang, K. J., Jun 15 2018, In : Science of the Total Environment. 627, p. 211-215 5 p.

Research output: Contribution to journalArticle

urban area
Health
Blood pressure
Air pollution
confidence interval
11 Citations (Scopus)
Protein-Tyrosine Kinases
Disease-Free Survival
Cytotoxic T-Lymphocytes
Bevacizumab
Myeloid-Derived Suppressor Cells
3 Citations (Scopus)

Chemotherapy Immunophenoprofiles in Non-Small-Cell Lung Cancer by Personalized Membrane Proteomics

Putri, D. U., Feng, P. H., Hsu, Y. H., Lee, K. Y., Jiang, F. W., Kuo, L. W., Chen, Y. J. & Han, C. L., Jan 1 2018, (Accepted/In press) In : Proteomics - Clinical Applications.

Research output: Contribution to journalArticle

Pemetrexed
Chemotherapy
Non-Small Cell Lung Carcinoma
Proteomics
Cisplatin
2 Citations (Scopus)
Computer aided diagnosis
Pattern recognition
Lung Neoplasms
Color
Bronchoscopy
6 Citations (Scopus)

Effects of physical characteristics of carbon black on metabolic regulation in mice

Chuang, H. C., Hsiao, T. C., Lee, C. H., Chun-Te Lin, J., Chuang, K. J., Feng, P. H. & Cheng, T. J., Jan 2018, In : Environmental Pollution. 232, p. 494-504

Research output: Contribution to journalArticle

Soot
Carbon black
NADP
Metabolism
Zeta potential
9 Citations (Scopus)

IGF-1R Promotes Symmetric Self-Renewal and Migration of Alkaline Phosphatase+ Germ Stem Cells through HIF-2α-OCT4/CXCR4 Loop under Hypoxia

Kuo, Y. C., Au, H. K., Hsu, J. L., Wang, H. F., Lee, C. J., Peng, S. W., Lai, S. C., Wu, Y. C., Ho, H. N. & Huang, Y. H., Feb 13 2018, In : Stem Cell Reports. 10, 2, p. 524-537 14 p.

Research output: Contribution to journalArticle

Stem cells
Germ Cells
Alkaline Phosphatase
Stem Cells
Insulin-Like Growth Factor I

Impact of prolonged and early bevacizumab treatment on the overall survival of EGFR-mutant and EGFR-wild type nonsquamous non-small cell lung cancer

Huang, Y. C., Shen, S. M., Liu, C. Y., Pavlidis, S., Wang, C. L., Ko, H. W., Chung, F. T., Lin, T. Y., Feng, P. H., Lee, K. Y., Guo, Y. K., Yang, C. T. & Kuo, C. H. S., Jan 1 2018, (Accepted/In press) In : Thoracic Cancer.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Survival
Confidence Intervals
Therapeutics
Vascular Endothelial Growth Factor A
4 Citations (Scopus)

Investigation into the pulmonary inflammopathology of exposure to nickel oxide nanoparticles in mice

Bai, K. J., Chuang, K. J., Chen, J. K., Hua, H. E., Shen, Y. L., Liao, W. N., Lee, C. H., Chen, K. Y., Lee, K. Y., Hsiao, T. C., Pan, C. H., Ho, K. F. & Chuang, H. C., Oct 1 2018, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 14, 7, p. 2329-2339 11 p.

Research output: Contribution to journalArticle

Nickel oxide
Nanoparticles
Lung
Pneumonia
Tissue
6 Citations (Scopus)

Lipoteichoic acid upregulates plasminogen activator inhibitor-1 expression in parapneumonic effusions

Lee, K. L., Chen, W. L., Chen, R. J., Lai, K. S. & Chung, C. L., Jan 1 2018, In : Respirology. 23, 1, p. 89-95 7 p.

Research output: Contribution to journalArticle

Plasminogen Activator Inhibitor 1
Up-Regulation
Gram-Positive Bacteria
Toll-Like Receptor 2
lipoteichoic acid

Lupus pneumonitis presenting with high titre of anti-ro antibody

Chen, M. C., Wu, Y. L., Lee, K. L., Lai, K. S. & Chung, C. L., Jan 1 2018, In : Respirology Case Reports. 6, 1, e00280.

Research output: Contribution to journalArticle

Anti-Idiotypic Antibodies
Pneumonia
Systemic Lupus Erythematosus
Lung
Serum
6 Citations (Scopus)

Pulmonary exposure to metal fume particulate matter cause sleep disturbances in shipyard welders

Chuang, H. C., Su, T. Y., Chuang, K. J., Hsiao, T. C., Lin, H. L., Hsu, Y. T., Pan, C. H., Lee, K. Y., Ho, S. C. & Lai, C. H., Jan 2018, In : Environmental Pollution. 232, p. 523-532

Research output: Contribution to journalArticle

Welding
Fumes
Particulate Matter
Shipyards
Sleep
5 Citations (Scopus)

S100A9+ MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: The role of RELB

Feng, P. H., Yu, C. T., Chen, K. Y., Luo, C. S., Wu, S. M., Liu, C. Y., Kuo, L. W., Chan, Y. F., Chen, T. T., Chang, C. C., Lee, C. N., Chuang, H. C., Lin, C. F., Han, C. L., Lee, W. H. & Lee, K. Y., Jan 26 2018, In : Oncotarget. 9, 7, p. 7631-7643 13 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Macrophages
Microarray Analysis
Blood Cells
Alveolar Macrophages
3 Citations (Scopus)
Trace Elements
Pleural Effusion
Lung Neoplasms
L-Lactate Dehydrogenase
Glucose 1-Dehydrogenase
11 Citations (Scopus)
Carbon Monoxide Poisoning
Meta-Analysis
Randomized Controlled Trials
Oxygen
Therapeutics
2 Citations (Scopus)

Unique immune gene expression patterns in bronchoalveolar lavage and tumor adjacent non-neoplastic lung tissue in non-small cell lung cancer

Kuo, C. H. S., Liu, C. Y., Pavlidis, S., Lo, Y. L., Wang, Y. W., Chen, C. H., Ko, H. W., Chung, F. T., Lin, T. Y., Wang, T. Y., Lee, K. Y., Guo, Y. K., Wang, T. H. & Yang, C. T., Feb 12 2018, In : Frontiers in Immunology. 9, FEB, 232.

Research output: Contribution to journalArticle

Bronchoalveolar Lavage
Non-Small Cell Lung Carcinoma
Gene Expression
Lung
Neoplasms
2017
7 Citations (Scopus)
Aryl Hydrocarbon Receptors
Methylcholanthrene
Nitric Oxide Synthase Type III
Hypertension
Blood pressure
3 Citations (Scopus)

Ankylosing spondylitis and the risk of cancer

Chang, C. C., Chang, C. W., Nguyen, P. A. A., Chang, T. H., Shih, Y. L., Chang, W. Y., Horng, J. T., Lee, O. K. S. & Ho, J. H. C., 2017, In : Oncology Letters. 14, 2, p. 1315-1322 8 p.

Research output: Contribution to journalArticle

Ankylosing Spondylitis
Neoplasms
Incidence
Confidence Intervals
Bone Neoplasms

Brain metastases in patients with non-small cell lung cancer: the role of mutated-EGFRs with an exon 19 deletion or L858R point mutation in cancer cell dissemination

Hsiao, S-H., Chou, Y-T., Lin, S-E., Hsu, R-C., Chung, C-L., Kao, Y-R., Liu, H. E. & Wu, C-W., Aug 8 2017, In : Oncotarget. 8, 32, p. 53405-53418 14 p.

Research output: Contribution to journalArticle

Point Mutation
Non-Small Cell Lung Carcinoma
Exons
Neoplasm Metastasis
Brain
27 Citations (Scopus)
Myositis
Polyneuropathies
Myasthenia Gravis
Non-Small Cell Lung Carcinoma
Muscle Weakness
20 Citations (Scopus)
Esophagectomy
Chemoradiotherapy
Radiotherapy
Thorax
Confidence Intervals
Epidermal Growth Factor Receptor
Squamous Cell Carcinoma
Lung Neoplasms
Adenocarcinoma
Radiotherapy
30 Citations (Scopus)

Elevation of YAP promotes the epithelial-mesenchymal transition and tumor aggressiveness in colorectal cancer

Ling, H. H., Kuo, C. C., Lin, B. X., Huang, Y. H. & Lin, C. W., Jan 1 2017, In : Experimental Cell Research. 350, 1, p. 218-225 8 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Colorectal Neoplasms
Neoplasms
Proteins
Neoplasm Metastasis
14 Citations (Scopus)

Expression of neuroendocrine factor VGF in lung cancer cells confers resistance to EGFR kinase inhibitors and triggers epithelial-to-mesenchymal transition

Hwang, W., Chiu, Y. F., Kuo, M. H., Lee, K. L., Lee, A. C., Yu, C. C., Chang, J. L., Huang, W. C., Hsiao, S. H., Lin, S. E. & Chou, Y. T., Jun 1 2017, In : Cancer Research. 77, 11, p. 3013-3026 14 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Lung Neoplasms
Phosphotransferases
Protein-Tyrosine Kinases
Neoplasms
20 Citations (Scopus)

Fluorescent nanodiamonds enable quantitative tracking of human mesenchymal stem cells in miniature pigs

Su, L. J., Wu, M. S., Hui, Y. Y., Chang, B. M., Pan, L., Hsu, P. C., Chen, Y. T., Ho, H. N., Huang, Y. H., Ling, T. Y., Hsu, H. H. & Chang, H. C., Mar 30 2017, In : Scientific Reports. 7, 45607.

Research output: Contribution to journalArticle

Nanodiamonds
Mesenchymal Stromal Cells
Swine
Placenta
Stem Cells
15 Citations (Scopus)

Hepatoma cell functions modulated by NEK2 are associated with liver cancer progression

Wu, S. M., Lin, S. L., Lee, K. Y., Chuang, H. C., Feng, P. H., Cheng, W. L., Liao, C. J., Chi, H. C., Lin, Y. H., Tsai, C. Y., Chen, W. J., Yeh, C. T. & Lin, K. H., Apr 1 2017, In : International Journal of Cancer. 140, 7, p. 1581-1596 16 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Hepatocellular Carcinoma
Drug Resistance
Centrosome
Neoplasm Metastasis
13 Citations (Scopus)
Peroxisome Proliferator-Activated Receptors
Epithelial-Mesenchymal Transition
Carnitine
Fibrosis
Kidney
3 Citations (Scopus)
Leukocyte Elastase
Interleukin-8
Smooth Muscle Myocytes
Smooth Muscle
RNA Polymerase II
14 Citations (Scopus)

Panobinostat sensitizes KRAS-mutant non-small-cell lung cancer to gefitinib by targeting TAZ

Lee, W. Y., Chen, P. C., Wu, W. S., Wu, H. C., Lan, C. H., Huang, Y. H., Cheng, C. H., Chen, K. C. & Lin, C. W., 2017, (Accepted/In press) In : International Journal of Cancer.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Histone Deacetylase Inhibitors
gefitinib
panobinostat
1 Citation (Scopus)

Proteasome activity related with the daily physical activity of COPD patients

Lee, K. Y., Chen, T. T., Chiang, L. L., Chuang, H. C., Feng, P. H., Liu, W. T., Chen, K. Y. & Ho, S. C., May 22 2017, In : International Journal of COPD. 12, p. 1519-1525 7 p.

Research output: Contribution to journalArticle

Proteasome Endopeptidase Complex
Chronic Obstructive Pulmonary Disease
Exercise
Healthy Volunteers
Ubiquitin
6 Citations (Scopus)

Pulmonary pathobiology induced by zinc oxide nanoparticles in mice: A 24-hour and 28-day follow-up study

Chuang, H. C., Chuang, K. J., Chen, J. K., Hua, H. E., Shen, Y. L., Liao, W. N., Lee, C. H., Pan, C. H., Chen, K. Y., Lee, K. Y., Hsiao, T. C. & Cheng, T. J., Jul 15 2017, In : Toxicology and Applied Pharmacology. 327, p. 13-22 10 p.

Research output: Contribution to journalArticle

Zinc Oxide
Nanoparticles
Lung
Respiratory system
Respiratory System
1 Citation (Scopus)

Realization of a CORDIC-Based Plug-In Accelerometer Module for PSG System in Head Position Monitoring for OSAS Patients

Lin, W. Y., Chou, W. C., Shiao, T. H., Shiao, G. M., Luo, C. S. & Lee, M. Y., Jan 1 2017, In : Journal of Healthcare Engineering. 2017, 4728187.

Research output: Contribution to journalArticle

Polysomnography
Physiologic Monitoring
Digital computers
Accelerometers
Head
2 Citations (Scopus)

SUV39H1 reduction is implicated in abnormal inflammation in COPD

Chen, T. T., Wu, S. M., Ho, S. C., Chuang, H. C., Liu, C. Y., Chan, Y. F., Kuo, L. W., Feng, P. H., Liu, W. T., Chen, K. Y., Hsiao, T. C., Juang, J. N. & Lee, K. Y., Jan 1 2017, In : Scientific Reports. 7, 46667.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Inflammation
Epithelial Cells
Interleukin-8
Lung
2016
4 Citations (Scopus)
Lung Volume Measurements
Air Pollution
Autophagy
Chronic Obstructive Pulmonary Disease
Oxygen
12 Citations (Scopus)

Effects of polycyclic aromatic compounds in fine particulate matter generated from household coal combustion on response to EGFR mutations in vitro

Ho, K. F., Chang, C-C., Tian, L., Chan, C. S., Musa Bandowe, B. A., Lui, K. H., Lee, K. Y., Chuang, K. J., Liu, C. Y., Ning, Z. & Chuang, H. C., Nov 1 2016, In : Environmental Pollution. 218, p. 1262-1269 8 p.

Research output: Contribution to journalArticle

Polycyclic Compounds
Particulate Matter
Coal
Aromatic compounds
Coal combustion
15 Citations (Scopus)

Effects of zinc oxide nanoparticles on human coronary artery endothelial cells

Chuang, K-J., Lee, K-Y., Pan, C. H., Lai, C. H., Lin, L. Y., Ho, S-C., Ho, K. F. & Chuang, H-C., Jul 1 2016, In : Food and Chemical Toxicology. 93, p. 138-144 7 p.

Research output: Contribution to journalArticle

Zinc Oxide
zinc oxide
Endothelial cells
coronary vessels
nanoparticles
17 Citations (Scopus)

Inflammation promotes expression of stemness-related properties in HBV-related hepatocellular carcinoma

Chang, T. S., Chen, C. L., Wu, Y. C., Liu, J. J., Kuo, Y. C., Lee, K. F., Lin, S. Y., Lin, S-E., Tung, S. Y., Kuo, L. M., Tsai, Y. H. & Huang, Y. H., Feb 1 2016, In : PLoS One. 11, 2, e0149897.

Research output: Contribution to journalArticle

Octamer Transcription Factors
hepatoma
Viruses
Hepatitis B virus
Hepatocellular Carcinoma
9 Citations (Scopus)
Chronic Obstructive Pulmonary Disease
Body Mass Index
Mortality
Confidence Intervals
Geriatric Assessment
41 Citations (Scopus)

NF-κB-driven suppression of FOXO3a contributes to EGFR mutation-independent gefitinib resistance

Chiu, C. F., Chang, Y. W., Kuo, K. T., Shen, Y. S., Liu, C. Y., Yu, Y. H., Cheng, C. C., Lee, K. Y., Chen, F. C., Hsu, M. K., Ku, T. C., Ma, J. T. & Su, J. L., May 3 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 18, p. E2526-E2535

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Lung Neoplasms
Mutation
Forkhead Transcription Factors
gefitinib
9 Citations (Scopus)
Malignant Pleural Effusion
Pleural Effusion
Biomarkers
Pleurisy
Interleukins