Research Center of Thoracic Medicine-Chronic Airway Disease

Research Output 2007 2019

  • 481 Citations
  • 14 h-Index
  • 57 Article
  • 2 Comment/debate
  • 2 Review article
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Article
2019

Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization

Chen, W-T., Hsu, W-T., Yen, M-H., Changou, C. A., Han, C-L., Chen, Y-J., Cheng, J-Y., Chang, T-H., Lee, O. K-S. & Ho, J. H-C., Jan 1 2019, In : Biomaterials. 190-191, p. 1-10 10 p.

Research output: Contribution to journalArticle

Catenins
Cell Polarity
Stem cells
Mesenchymal Stromal Cells
Shear stress
1 Citation (Scopus)
Pulmonary diseases
pneumonia
Air pollution
atmospheric pollution
confidence interval

FOSB-PCDHB13 axis disrupts the microtubule network in non-small cell lung cancer

Ting, C. H., Lee, K. Y., Wu, S. M., Feng, P. H., Chan, Y. F., Chen, Y. C. & Chen, J. Y., Jan 1 2019, In : Cancers. 11, 1, 107.

Research output: Contribution to journalArticle

Open Access
Non-Small Cell Lung Carcinoma
Microtubules
Tilapia
Mortality
Chromatin Immunoprecipitation
1 Citation (Scopus)

Induction of nuclear protein-1 by thyroid hormone enhances platelet-derived growth factor a mediated angiogenesis in liver cancer

Chen, C. Y., Wu, S. M., Lin, Y. H., Chi, H. C., Lin, S. L., Yeh, C. T., Chuang, W. Y. & Lin, K. H., Jan 1 2019, In : Theranostics. 9, 8, p. 2361-2379 19 p.

Research output: Contribution to journalArticle

Open Access
Platelet-Derived Growth Factor
Liver Neoplasms
Nuclear Proteins
Thyroid Hormones
Hepatocellular Carcinoma
Haptoglobins
Chronic Obstructive Pulmonary Disease
Inflammation
Phenotype
Alveolar Epithelial Cells
2018
9 Citations (Scopus)
Protein-Tyrosine Kinases
Disease-Free Survival
Cytotoxic T-Lymphocytes
Bevacizumab
Myeloid-Derived Suppressor Cells
3 Citations (Scopus)

Chemotherapy Immunophenoprofiles in Non-Small-Cell Lung Cancer by Personalized Membrane Proteomics

Putri, D. U., Feng, P. H., Hsu, Y. H., Lee, K. Y., Jiang, F. W., Kuo, L. W., Chen, Y. J. & Han, C. L., Jan 1 2018, (Accepted/In press) In : Proteomics - Clinical Applications.

Research output: Contribution to journalArticle

Pemetrexed
Chemotherapy
Non-Small Cell Lung Carcinoma
Proteomics
Cisplatin
2 Citations (Scopus)
Computer aided diagnosis
Pattern recognition
Lung Neoplasms
Color
Bronchoscopy
2 Citations (Scopus)

Effects of diesel exhaust particles on the expression of tau and autophagy proteins in human neuroblastoma cells

Bai, K. J., Chuang, K. J., Wu, S. M., Chang, L. T., Chang, T. Y., Ho, K. F. & Chuang, H. C., Sep 1 2018, In : Environmental Toxicology and Pharmacology. 62, p. 54-59 6 p.

Research output: Contribution to journalArticle

Vehicle Emissions
tau Proteins
Autophagy
Neuroblastoma
Soot
10 Citations (Scopus)

ROS-independent ER stress-mediated NRF2 activation promotes warburg effect to maintain stemness-associated properties of cancer-initiating cells

Chang, C. W., Chen, Y. S., Tsay, Y. G., Han, C. L., Chen, Y. J., Yang, C. C., Hung, K. F., Lin, C. H., Huang, T. Y., Kao, S. Y., Lee, T. C. & Lo, J. F., Feb 1 2018, In : Cell Death and Disease. 9, 2, 194.

Research output: Contribution to journalArticle

Neoplasms
Maintenance
Acetyl Coenzyme A
Citric Acid Cycle
Neoplastic Stem Cells
4 Citations (Scopus)

S100A9+ MDSC and TAM-mediated EGFR-TKI resistance in lung adenocarcinoma: The role of RELB

Feng, P. H., Yu, C. T., Chen, K. Y., Luo, C. S., Wu, S. M., Liu, C. Y., Kuo, L. W., Chan, Y. F., Chen, T. T., Chang, C. C., Lee, C. N., Chuang, H. C., Lin, C. F., Han, C. L., Lee, W. H. & Lee, K. Y., Jan 26 2018, In : Oncotarget. 9, 7, p. 7631-7643 13 p.

Research output: Contribution to journalArticle

Protein-Tyrosine Kinases
Macrophages
Microarray Analysis
Blood Cells
Alveolar Macrophages
4 Citations (Scopus)

Stimulation of Interferon-Stimulated Gene 20 by Thyroid Hormone Enhances Angiogenesis in Liver Cancer

Lin, S. L., Wu, S. M., Chung, I. H., Lin, Y. H., Chen, C. Y., Chi, H. C., Lin, T. K., Yeh, C. T. & Lin, K. H., Jan 1 2018, In : Neoplasia (United States). 20, 1, p. 57-68 12 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Thyroid Hormones
Interferons
Chromatin Immunoprecipitation
Genes
6 Citations (Scopus)

Subcellular Proteome Landscape of Human Embryonic Stem Cells Revealed Missing Membrane Proteins

Weldemariam, M. M., Han, C-L., Shekari, F., Kitata, R. B., Chuang, C-Y., Hsu, W-T., Kuo, H-C., Choong, W-K., Sung, T-Y., He, F-C., Chung, M. C. M., Salekdeh, G. H. & Chen, Y-J., Dec 7 2018, In : Journal of Proteome Research. 17, 12, p. 4138-4151 14 p.

Research output: Contribution to journalArticle

Proteome
Stem cells
Membrane Proteins
Proteins
Peptides
3 Citations (Scopus)
Trace Elements
Pleural Effusion
Lung Neoplasms
L-Lactate Dehydrogenase
Glucose 1-Dehydrogenase
6 Citations (Scopus)

β-Amyloid Induces Pathology-Related Patterns of Tau Hyperphosphorylation at Synaptic Terminals

Wu, H-Y., Kuo, P-C., Wang, Y-T., Lin, H-T., Roe, A. D., Wang, B. Y., Han, C-L., Hyman, B. T., Chen, Y-J. & Tai, H-C., Sep 1 2018, In : Journal of Neuropathology and Experimental Neurology. 77, 9, p. 814-826 13 p.

Research output: Contribution to journalArticle

Presynaptic Terminals
Amyloid
Phosphotransferases
Proline
Pathology

初階臨床體驗課程對醫學生專業素養及基礎醫學學習成效之影響

Translated title of the contribution: Effects of Early Clinical Exposure Courses on the Professionalism and Basic Medicine Learning Outcomes of Medical Students唐功培, 陳資濤 & 蔡博方, Sep 2018, In : 教學實踐與創新.

Research output: Contribution to journalArticle

Open Access
medical student
medicine
learning
mentoring
tutor
2017
19 Citations (Scopus)
Antrodia
Taiwanofungus camphoratus
Ubiquinone
Neoplastic Stem Cells
ubiquinones
16 Citations (Scopus)

EGFR mutation, smoking, and gender in advanced lung adenocarcinoma

Tseng, C. H., Chiang, C. J., Tseng, J. S., Yang, T. Y., Hsu, K. H., Chen, K. C., Wang, C. L., Chen, C. Y., Yen, S. H., Tsai, C. M., Huang, M. S., Ho, C. C., Yu, C. J., Tsai, Y. H., Chen, J. S., Chou, T. Y., Tsai, M. H., Chen, H. Y., Su, K. Y., Chen, J. J. W. & 4 others, Chen, H. W., Yu, S. L., Liu, T. W. & Chang, G. C., Jan 1 2017, In : Oncotarget. 8, 58, p. 98384-98393 10 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Smoking
Mutation
Survival
Mutation Rate
8 Citations (Scopus)

Heat shock protein70 is implicated in modulating NF-κ B activation in alveolar macrophages of patients with active pulmonary tuberculosis

Wang, C. H., Chou, P. C., Chung, F. T., Lin, H. C., Huang, K. H. & Kuo, H. P., Dec 1 2017, In : Scientific Reports. 7, 1, 1214.

Research output: Contribution to journalArticle

Alveolar Macrophages
Pulmonary Tuberculosis
Shock
Tuberculosis
Hot Temperature
15 Citations (Scopus)

Hepatoma cell functions modulated by NEK2 are associated with liver cancer progression

Wu, S. M., Lin, S. L., Lee, K. Y., Chuang, H. C., Feng, P. H., Cheng, W. L., Liao, C. J., Chi, H. C., Lin, Y. H., Tsai, C. Y., Chen, W. J., Yeh, C. T. & Lin, K. H., Apr 1 2017, In : International Journal of Cancer. 140, 7, p. 1581-1596 16 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Hepatocellular Carcinoma
Drug Resistance
Centrosome
Neoplasm Metastasis
7 Citations (Scopus)

Identification of Potential Plasma Biomarkers for Nonalcoholic Fatty Liver Disease by Integrating Transcriptomics and Proteomics in Laying Hens

Tsai, M. T., Chen, Y. J., Chen, C. Y., Tsai, M. H., Han, C. L., Chen, Y. J., Mersmann, H. J. & Ding, S. T., Mar 1 2017, In : The Journal of nutrition. 147, 3, p. 293-303 11 p.

Research output: Contribution to journalArticle

Proteomics
Biomarkers
Chickens
Liver
Dipeptidyl Peptidase 4
3 Citations (Scopus)

Membrane proteomics of impaired energetics and cytoskeletal disorganization in elderly diet-induced diabetic mice

Hung, C. L., Pan, S. H., Han, C. L., Chang, C. W., Hsu, Y. L., Su, C. H., Shih, S. C., Lai, Y. J., Chiau, J. S. C., Yeh, H. I., Liu, C. Y., Lee, H. C. & Lam, C. S. P., Oct 6 2017, In : Journal of Proteome Research. 16, 10, p. 3504-3513 10 p.

Research output: Contribution to journalArticle

Diabetic Diet
Nutrition
Proteomics
Membranes
Cardiac Myocytes
1 Citation (Scopus)
Proteasome Endopeptidase Complex
Chronic Obstructive Pulmonary Disease
Exercise
Healthy Volunteers
Ubiquitin
7 Citations (Scopus)

Proteome analysis of human embryonic stem cells organelles

Shekari, F., Nezari, H., Larijani, M. R., Han, C. L., Baharvand, H., Chen, Y. J. & Salekdeh, G. H., Jun 6 2017, In : Journal of Proteomics. 162, p. 108-118 11 p.

Research output: Contribution to journalArticle

Proteome
Stem cells
Organelles
Protein Databases
Membrane Proteins
1 Citation (Scopus)

SUV39H1 reduction is implicated in abnormal inflammation in COPD

Chen, T. T., Wu, S. M., Ho, S. C., Chuang, H. C., Liu, C. Y., Chan, Y. F., Kuo, L. W., Feng, P. H., Liu, W. T., Chen, K. Y., Hsiao, T. C., Juang, J. N. & Lee, K. Y., Jan 1 2017, In : Scientific Reports. 7, 46667.

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Inflammation
Epithelial Cells
Interleukin-8
Lung
8 Citations (Scopus)
Fatal Outcome
Pulmonary Tuberculosis
Cohort Studies
Therapeutics
Molecular Pathology
2016
3 Citations (Scopus)
Lung Volume Measurements
Air Pollution
Autophagy
Chronic Obstructive Pulmonary Disease
Oxygen
2 Citations (Scopus)

Exercise-Induced Changes in Exhaled NO Differentiates Asthma with or Without Fixed Airway Obstruction from COPD with Dynamic Hyperinflation

Huang, S. Y., Chou, P. C., Wang, T. Y., Lo, Y. L., Joa, W. C., Chen, L. F., Sheng, T. F., Chung, K. F., Wang, C. H. & Kuo, H. P., Apr 1 2016, In : Medicine (United States). 95, 15, e3400.

Research output: Contribution to journalArticle

Airway Obstruction
Chronic Obstructive Pulmonary Disease
Asthma
Exercise
Nitric Oxide
3 Citations (Scopus)

Higher frequency but random distribution of EGFR mutation subtypes in familial lung cancer patients

Hsu, K. H., Tseng, J. S., Wang, C. L., Yang, T. Y., Tseng, C. H., Chen, H. Y., Chen, K. C., Tsai, C. R., Yang, C. T., Yu, S. L., Su, K. Y., Yu, C. J., Ho, C. C., Hsia, T. C., Wu, M. F., Chiu, K. L., Liu, C. M., Yang, P. C., Chen, J. J. W. & Chang, G. C., Aug 1 2016, In : Oncotarget. 7, 33, p. 53299-53308 10 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Lung Neoplasms
Mutation
Mutation Rate
Mutagenesis
6 Citations (Scopus)
Chronic Obstructive Pulmonary Disease
Body Mass Index
Mortality
Confidence Intervals
Geriatric Assessment
9 Citations (Scopus)
Malignant Pleural Effusion
Pleural Effusion
Biomarkers
Pleurisy
Interleukins
14 Citations (Scopus)

Protein oxidation and degradation caused by particulate matter

Lai, C-H., Lee, C-N., Bai, K-J., Yang, Y-L., Chuang, K-J., Wu, S-M. & Chuang, H-C., Sep 20 2016, In : Scientific Reports. 6, p. 33727

Research output: Contribution to journalArticle

Vehicle Emissions
Particulate Matter
Autophagy
Proteolysis
Ubiquitin
3 Citations (Scopus)

Pulmonary rehabilitation coupled with negative pressure ventilation decreases decline in lung function, hospitalizations, and medical cost in COPD: A 5-year study

Huang, H. Y., Chou, P. C., Joa, W. C., Chen, L. F., Sheng, T. F., Lin, H. C., Yang, L. Y., Pan, Y. B., Chung, F. T., Wang, C. H. & Kuo, H. P., Oct 1 2016, In : Medicine. 95, 41, p. e5119

Research output: Contribution to journalArticle

Chronic Obstructive Pulmonary Disease
Ventilation
Hospitalization
Rehabilitation
Pressure
1 Citation (Scopus)

Streptococcal pyrogenic exotoxin B inhibits apoptotic cell clearance by macrophages through protein S cleavage

Chen, C. L., Wu, Y. Y., Lin, C. F., Kuo, C. F., Han, C. L., Wang, S., Chuang, W. J., Chen, C. Y., Wu, J. J., Tsai, P. J., Liu, C. C. & Lin, Y. S., May 16 2016, In : Scientific Reports. 6, 26026.

Research output: Contribution to journalArticle

Protein S
Macrophages
streptopain
Streptococcus
Phagocytosis
18 Citations (Scopus)

Thyroid hormone suppresses hepatocarcinogenesis via DAPK2 and SQSTM1-dependent selective autophagy

Chi, H. C., Chen, S. L., Tsai, C. Y., Chuang, W. Y., Huang, Y. H., Tsai, M. C., Wu, S. M., Sun, C. P., Yeh, C. T. & Lin, K. H., Dec 1 2016, In : Autophagy. 12, 12, p. 2271-2285 15 p.

Research output: Contribution to journalArticle

Death-Associated Protein Kinases
Autophagy
Thyroid Hormones
Diethylnitrosamine
Hepatocellular Carcinoma
2015
11 Citations (Scopus)

Associated bone mineral density and obstructive sleep apnea in chronic obstructive pulmonary disease

Wang, T. Y., Lo, Y. L., Chou, P. C., Chung, F. T., Lin, S. M., Lin, T. Y., Lin, H. C., Wang, C. H., Yu, C. T. & Kuo, H. P., Jan 29 2015, In : International Journal of COPD. 10, p. 231-237 7 p.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Bone Density
Chronic Obstructive Pulmonary Disease
Total Lung Capacity
Polysomnography
10 Citations (Scopus)

Circulating Angiopopietin-1 Correlates with the Clinical Course of Multiple Organ Dysfunction Syndrome and Mortality in Patients with Severe Sepsis

Lin, S. M., Chung, F. T., Kuo, C. H., Chou, P. C., Wang, T. Y., Chang, P. J., Lo, Y. L., Huang, C. D., Lin, H. C., Wang, C. H., Kuo, H. P. & Eriksson., E., Jan 1 2015, In : Medicine (United States). 94, 20, e878.

Research output: Contribution to journalArticle

Angiopoietin-1
Multiple Organ Failure
Sepsis
Angiopoietin-2
Mortality
4 Citations (Scopus)

EGFR mutation and lobar location of lung adenocarcinoma

Tseng, C. H., Chen, K. C., Hsu, K. H., Tseng, J. S., Ho, C. C., Hsia, T. C., Su, K. Y., Wu, M. F., Chiu, K. L., Liu, C. M., Wu, T. C., Chen, H. J., Chen, H. Y., Chang, C. S., Hsu, C. P., Hsia, J. Y., Chuang, C. Y., Lin, C. H., Chen, J. J. W., Chen, K. Y. & 7 others, Liao, W. Y., Shih, J. Y., Yu, S. L., Yu, C. J., Yang, P. C., Yang, T. Y. & Chang, G. C., Sep 8 2015, In : Carcinogenesis. 37, 2, p. 157-162 6 p.

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Mutation
Exons
Lung Neoplasms
erbB-1 Genes
20 Citations (Scopus)

Fibrocyte trafficking in patients with chronic obstructive asthma and during an acute asthma exacerbation

Wang, C. H., Punde, T. H., Huang, C. D., Chou, P. C., Huang, T. T., Wu, W. H., Liu, C. H., Chung, K. F. & Kuo, H. P., May 1 2015, In : Journal of Allergy and Clinical Immunology. 135, 5, p. 1154-1162e5

Research output: Contribution to journalArticle

Asthma
Chemokine CCL19
Chemokine CXCL12
Chemokine Receptors
Chemotactic Factors
15 Citations (Scopus)

Improvement in the prediction of ventilator weaning outcomes by an artificial neural network in a medical ICU

Kuo, H. J., Chiu, H. W., Lee, C. N., Chen, T. T., Chang, C. C. & Bien, M. Y., Nov 1 2015, In : Respiratory Care. 60, 11, p. 1560-1569 10 p.

Research output: Contribution to journalArticle

Ventilator Weaning
Respiration
Neural Networks (Computer)
Weaning
Artificial Respiration
10 Citations (Scopus)
Particulate Matter
Air Pollution
Environmental Exposure
Chronic Obstructive Pulmonary Disease
Biomarkers
17 Citations (Scopus)

Mitochondrial translocation of EGFR regulates mitochondria dynamics and promotes metastasis in NSCLC

Che, T. F., Lin, C. W., Wu, Y. Y., Chen, Y. J., Han, C. L., Chang, Y. L., Wu, C. T., Hsiao, T. H., Hong, T. M. & Yang, P. C., 2015, In : Oncotarget. 6, 35, p. 37349-37366 18 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Mitochondria
Mitochondrial Dynamics
Neoplasm Metastasis
Neoplasms
7 Citations (Scopus)

Proteoglycan 4 is a diagnostic biomarker for COPD

Lee, K. Y., Chuang, H. C., Chen, T. T., Liu, W. T., Su, C-L., Feng, P. H., Chiang, L. L., Bien, M. Y. & Ho, S. C., Sep 18 2015, In : International Journal of COPD. 10, 1, p. 1999-2007 9 p.

Research output: Contribution to journalArticle

Proteoglycans
Chronic Obstructive Pulmonary Disease
Biomarkers
C-Reactive Protein
Lung
2014
11 Citations (Scopus)

Characterization of the interactions between protein and carbon black

Chen, T. T., Chuang, K. J., Chiang, L. L., Chen, C. C., Yeh, C-T., Wang, L. S., Gregory, C., Jones, T., BéruBé, K., Lee, C-N., Chuang, H. C. & Cheng, T. J., Jan 15 2014, In : Journal of Hazardous Materials. 264, p. 127-135 9 p.

Research output: Contribution to journalArticle

Soot
black carbon
Carbon black
Proteins
protein
16 Citations (Scopus)

Clinical characteristics and treatment outcomes of patients with low- and high-concentration isoniazid-monoresistant tuberculosis

Wang, T. Y., Lin, S. M., Shie, S. S., Chou, P. C., Huang, C. D., Chung, F. T., Kuo, C. H., Chang, P. J. & Kuo, H. P., Jan 22 2014, In : PLoS One. 9, 1, e86316.

Research output: Contribution to journalArticle

isoniazid
Pyrazinamide
Isoniazid
Rifampin
tuberculosis
8 Citations (Scopus)
Pyrazinamide
Rifampin
Ethambutol
Tuberculosis
Pharmacokinetics
14 Citations (Scopus)

Mobile-phone-based home exercise training program decreases systemic inflammation in COPD: A pilot study

Wang, C. H., Chou, P. C., Joa, W. C., Chen, L. F., Sheng, T. F., Ho, S. C., Lin, H. C., Huang, C. D., Chung, F. T., Chung, K. F. & Kuo, H. P., 2014, In : BMC Pulmonary Medicine. 14, 1, 142.

Research output: Contribution to journalArticle

Cell Phones
Chronic Obstructive Pulmonary Disease
Exercise
Inflammation
Education

The effectiveness of care bundles in maintaining the skin integrity and reducing the incidence density of pressure ulcers in lung cancer inpatients

Lin, W. L., Tseng, C. H., Chung, Y. J., Chuang, H. C., Lin, Y. L. & Chang, P. H., Jan 1 2014, In : Journal of Nursing. 61, p. S85-S94

Research output: Contribution to journalArticle

Patient Care Bundles
Pressure Ulcer
Inpatients
Lung Neoplasms
Skin
2013
12 Citations (Scopus)

An iTRAQ proteomic study reveals an association between diet-induced enhanced fatty acid metabolism and the development of glucose intolerance in prediabetic mice

Ho, J. H., Lee, O. K., Fu, Y. J., Shih, H. T., Tseng, C. Y., Chung, C. C., Han, C. L. & Chen, Y. J., 2013, In : Journal of Proteome Research. 12, 3, p. 1120-1133 14 p.

Research output: Contribution to journalArticle

Glucose Intolerance
High Fat Diet
Nutrition
Metabolism
Proteomics
9 Citations (Scopus)

Chronic cough and obstructive sleep apnoea in a sleep laboratory-based pulmonary practice

Wang, T. Y., Lo, Y. L., Liu, W. T., Lin, S. M., Lin, T. Y., Kuo, C. H., Chung, F. T., Chou, P. C., Chang, P. J., Ni, Y. L., Ho, S. C., Lin, H. C., Wang, C. H., Yu, C. T. & Kuo, H. P., Nov 5 2013, In : Cough. 9, 1, 24.

Research output: Contribution to journalArticle

Obstructive Sleep Apnea
Cough
Sleep
Lung
Continuous Positive Airway Pressure