Research Output 2014 2020

  • 700 Citations
  • 15 h-Index
  • 69 Article
  • 3 Review article
17 Citations (Scopus)

(N-Hydroxycarbonylbenylamino)quinolines as Selective Histone Deacetylase 6 Inhibitors Suppress Growth of Multiple Myeloma in Vitro and in Vivo

Lee, H. Y., Nepali, K., Huang, F. I., Chang, C. Y., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Feb 8 2018, In : Journal of Medicinal Chemistry. 61, 3, p. 905-917 13 p.

Research output: Contribution to journalArticle

Quinolines
Histone Deacetylase Inhibitors
Multiple Myeloma
Growth
Hydroxamic Acids
2 Citations (Scopus)

1,4-Naphthoquinones as inhibitors of Itch, a HECT domain-E3 ligase, and tumor growth suppressors in multiple myeloma

Liu, Y. M., HuangFu, W. C., Huang, H. L., Wu, W. C., Chen, Y. L., Yen, Y., Huang, H. L., Nien, C. Y., Lai, M. J., Pan, S. L. & Liou, J. P., Nov 10 2017, In : European Journal of Medicinal Chemistry. 140, p. 84-91 8 p.

Research output: Contribution to journalArticle

Ubiquitin-Protein Ligases
Multiple Myeloma
Tumors
Lead compounds
Growth
8 Citations (Scopus)

1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC

Ojha, R., Huang, H. L., HuangFu, W. C., Wu, Y. W., Nepali, K., Lai, M. J., Su, C. J., Sung, T. Y., Chen, Y. L., Pan, S. L. & Liou, J. P., Apr 25 2018, In : European Journal of Medicinal Chemistry. 150, p. 667-677 11 p.

Research output: Contribution to journalArticle

Hydroxamic Acids
Histone Deacetylase Inhibitors
Antineoplastic Agents
Protein Isoforms
Cells
13 Citations (Scopus)
Histone Deacetylase Inhibitors
Tumors
Prostatic Neoplasms
Cells
Lead compounds
5 Citations (Scopus)

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
5 Citations (Scopus)

2-(Phenylsulfonyl)quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase

Lee, H. Y., Chang, C. Y., Su, C. J., Huang, H. L., Mehndiratta, S., Chao, Y. H., Hsu, C. M., Kumar, S., Sung, T. Y., Huang, Y. Z., Li, Y. H., Yang, C. R. & Liou, J. P., Oct 21 2016, In : European Journal of Medicinal Chemistry. 122, p. 92-101 10 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Antineoplastic Agents
Acetylation
Acrylamide
Structure-Activity Relationship
6 Citations (Scopus)

2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition

Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J. Y., Liou, J. P. & Lee, H. Y., 2015, In : Organic and Biomolecular Chemistry. 14, 2, p. 716-723 8 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
Dione
Tubulin
Antineoplastic Agents
Inhibitory Concentration 50
9 Citations (Scopus)

3-Aroylindoles display antitumor activity in vitro and in vivo: Effects of N1-substituents on biological activity

Lee, H-Y., Lee, J. F., Kumar, S., Wu, Y. W., HuangFu, W-C., Lai, M-J., Li, Y-H., Huang, H. L., Kuo, F. C., Hsiao, C. J., Cheng, C. C., Yang, C. R. & Liou, J-P., Jan 5 2017, In : European Journal of Medicinal Chemistry. 125, p. 1268-1278 11 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Tubulin
Bioactivity
Hydroxamic Acids
Tubulin Modulators
8 Citations (Scopus)

4-Indolyl-N-hydroxyphenylacrylamides as potent HDAC class I and IIB inhibitors in vitro and in vivo

Mehndiratta, S., Wang, R. S., Huang, H. L., Su, C. J., Hsu, C. M., Wu, Y. W., Pan, S. L. & Liou, J. P., Jul 7 2017, In : European Journal of Medicinal Chemistry. 134, p. 13-23 11 p.

Research output: Contribution to journalArticle

Heterografts
Tumors
Bearings (structural)
Histone Deacetylase Inhibitors
Acrylamide
12 Citations (Scopus)

5-Aroylindoles Act as Selective Histone Deacetylase 6 Inhibitors Ameliorating Alzheimer's Disease Phenotypes

Lee, H. Y., Fan, S. J., Huang, F. I., Chao, H. Y., Hsu, K. C., Lin, T. E., Yeh, T. K., Lai, M. J., Li, Y. H., Huang, H. L., Yang, C. R. & Liou, J. P., Jan 29 2018, (Accepted/In press) In : Journal of Medicinal Chemistry.

Research output: Contribution to journalArticle

tau Proteins
Histone Deacetylase Inhibitors
Alzheimer Disease
Hydroxamic Acids
Phenotype
25 Citations (Scopus)
Transforming Growth Factors
Angiotensin II
Androgens
Testosterone
Fibroblasts
3 Citations (Scopus)

An oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cells

Chao, M. W., Huang, H. L., HuangFu, W. C., Hsu, K. C., Liu, Y. M., Wu, Y. W., Lin, C. F., Chen, Y. L., Lai, M. J., Lee, H. Y., Liou, J. P., Teng, C. M. & Yang, C. R., 2017, In : Oncotarget. 8, 17, p. 27772-27785 14 p.

Research output: Contribution to journalArticle

Leukemia
Pharmaceutical Preparations
Neoplasms
Glycoproteins
National Cancer Institute (U.S.)
7 Citations (Scopus)

A novel action mechanism for MPT0g013, a derivative of arylsulfonamide, inhibits tumor angiogenesis through upregulation of TIMP3 expression

Wang, C-Y., Liou, J. P., Tsai, A-C., Lai, M-J., Liu, Y-M., Lee, H. Y., Wang, J-C., Pan, S. L. & Teng, C-M., 2014, In : Oncotarget. 5, 20, p. 9838-9850 13 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-3
Up-Regulation
Neoplasms
Cell Cycle Resting Phase
Proteins
22 Citations (Scopus)

A novel class I HDAC inhibitor, MPT0G030, induces cell apoptosis and differentiation in human colorectal cancer cells via HDAC1/PKCδ and E-cadherin

Wang, L. T., Liou, J. P., Li, Y. H., Liu, Y. M., Pan, S. L. & Teng, C. M., 2014, In : Oncotarget. 5, 14, p. 5651-5662 12 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Cadherins
Protein Kinase C
Cell Differentiation
Colorectal Neoplasms
3 Citations (Scopus)

A novel dual HDAC6 and tubulin inhibitor, MPT0B451, displays anti-tumor ability in human cancer cells in vitro and in vivo

Wu, Y. W., Hsu, K. C., Lee, H. Y., Huang, T. C., Lin, T. E., Chen, Y. L., Sung, T. Y., Liou, J. P., Hwang-Verslues, W. W., Pan, S. L. & HuangFu, W. C., Mar 13 2018, In : Frontiers in Pharmacology. 9, MAR, 205.

Research output: Contribution to journalArticle

Tubulin Modulators
Histone Deacetylases
Neoplasms
Tubulin
Molecular Docking Simulation
3 Citations (Scopus)

A novel tubulin polymerization inhibitor, MPT0B206, downregulates Bcr-Abl expression and induces apoptosis in imatinib-sensitive and imatinib-resistant CML cells

Chen, C. W., Lee, Y. L., Liou, J. P., Liu, Y. H., Liu, C. W., Chen, T. Y. & Huang, H. M., Sep 1 2016, In : Apoptosis. 21, 9, p. 1008-1018 11 p.

Research output: Contribution to journalArticle

Tubulin Modulators
K562 Cells
Myeloid Cells
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Down-Regulation
11 Citations (Scopus)

Anticancer activity of MPT0G157, a derivative of indolylbenzenesulfonamide, inhibits tumor growth and angiogenesis

Huang, Y. C., Huang, F. I., Mehndiratta, S., Lai, S. C., Liou, J. P. & Yang, C. R., 2015, In : Oncotarget. 6, 21, p. 18590-18601 12 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Growth
Neoplasms
HCT116 Cells
HSP90 Heat-Shock Proteins
2 Citations (Scopus)

Anti-leukemia effects of the novel synthetic 1-benzylindole derivative 21-900 in vitro and in vivo

Huangfu, W. C., Chao, M. W., Cheng, C. C., Wei, Y. C., Wu, Y. W., Liou, J. P., Hsiao, G., Lee, Y. C. & Yang, C. R., Feb 9 2017, In : Scientific Reports. 7, 42291.

Research output: Contribution to journalArticle

Tubulin
Leukemia
Apoptosis
Caspase 7
Drug Therapy
3 Citations (Scopus)

Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo

Hsieh, Y. L., Tu, H. J., Pan, S. L., Liou, J. P. & Yang, C. R., Jun 1 2019, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 6, p. 992-1003 12 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Histone Deacetylase Inhibitors
Breast Neoplasms
Histone Deacetylases
Acetylation
15 Citations (Scopus)

Antimitotic and antivascular activity of heteroaroyl-2-hydroxy-3,4,5-trimethoxybenzenes

Lee, H. Y., Chang, C-Y., Lai, M-J., Chuang, H-Y., Kuo, C-C., Chang, C-Y., Chang, J-Y. & Liou, J. P., Jul 23 2015, In : Bioorganic and Medicinal Chemistry. 23, 15, p. 4230-4236 7 p.

Research output: Contribution to journalArticle

Antimitotic Agents
KB Cells
Colchicine
Tubulin
Polymerization
7 Citations (Scopus)

Antimitotic and vascular disrupting agents: 2-Hydroxy-3,4,5- trimethoxybenzophenones

Chang, C. Y., Chuang, H. Y., Lee, H. Y., Yeh, T. K., Kuo, C. C., Chang, C. Y., Chang, J. Y. & Liou, J. P., Apr 22 2014, In : European Journal of Medicinal Chemistry. 77, p. 306-314 9 p.

Research output: Contribution to journalArticle

Benzophenones
Antimitotic Agents
KB Cells
Endothelial cells
Human Umbilical Vein Endothelial Cells
33 Citations (Scopus)

Azaindolylsulfonamides, with a more selective inhibitory effect on histone deacetylase 6 activity, exhibit antitumor activity in colorectal cancer HCT116 cells

Lee, H. Y., Tsai, A. C., Chen, M. C., Shen, P. J., Cheng, Y. C., Kuo, C. C., Pan, S. L., Liu, Y. M., Liu, J. F., Yeh, T. K., Wang, J. C., Chang, C. Y., Chang, J. Y. & Liou, J. P., May 22 2014, In : Journal of Medicinal Chemistry. 57, 10, p. 4009-4022 14 p.

Research output: Contribution to journalArticle

HCT116 Cells
Histone Deacetylases
Colorectal Neoplasms
Histone Deacetylase Inhibitors
Heterografts
6 Citations (Scopus)

Concise syntheses of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents

Mehndiratta, S., Chiang, Y-F., Lai, M-J., Lee, H. Y., Chen, M. C., Kuo, C-C., Chang, C-Y., Chang, J-Y. & Liou, J. P., Sep 1 2014, In : Bioorganic and Medicinal Chemistry. 22, 17, p. 4917-4923 7 p.

Research output: Contribution to journalArticle

Antimitotic Agents
Blood Vessels
Cells
Cell Line
G2 Phase

Correction: 2-Aroylquinoline-5,8-diones as potent anticancer agents displaying tubulin and heat shock protein 90 (HSP90) inhibition (Org. Biomol. Chem. (2016) 14 (716-723))

Nepali, K., Kumar, S., Huang, H. L., Kuo, F. C., Lee, C. H., Kuo, C. C., Yeh, T. K., Li, Y. H., Chang, J. Y., Liou, J. P. & Lee, H. Y., Jan 1 2018, In : Organic and Biomolecular Chemistry. 16, 25, p. 4734 1 p.

Research output: Contribution to journalArticle

HSP90 Heat-Shock Proteins
Dione
Tubulin
Antineoplastic Agents
Emotions
10 Citations (Scopus)
Curcumin
Extracellular Matrix
Fibroblasts
Angiotensin II
Transforming Growth Factors
16 Citations (Scopus)

Denbinobin upregulates miR-146a expression and attenuates IL-1β-induced upregulation of ICAM-1 and VCAM-1 expressions in osteoarthritis fibroblast-like synoviocytes

Yang, C. R., Shih, K. S., Liou, J. P., Wu, Y. W., Hsieh, I. N., Lee, H. Y., Lin, T. C. & Wang, J. H., Oct 22 2014, In : Journal of Molecular Medicine. 92, 11, p. 1147-1158 12 p.

Research output: Contribution to journalArticle

Vascular Cell Adhesion Molecule-1
Intercellular Adhesion Molecule-1
MicroRNAs
Interleukin-1
Osteoarthritis
10 Citations (Scopus)

Dual inhibition of PIK3C3 and FGFR as a new therapeutic approach to treat bladder cancer

Chen, C. H., Changou, C. A., Hsieh, T. H., Lee, Y. C., Chu, C. Y., Hsu, K. C., Wang, H. C., Lin, Y. C., Lo, Y. N., Liu, Y. R., Liou, J. P. & Yen, Y., Mar 1 2018, In : Clinical Cancer Research. 24, 5, p. 1176-1189 14 p.

Research output: Contribution to journalArticle

Autophagy
Urinary Bladder Neoplasms
Cell Death
Therapeutics
Clustered Regularly Interspaced Short Palindromic Repeats
15 Citations (Scopus)

Early investigational tubulin inhibitors as novel cancer therapeutics

Nepali, K., Ojha, R., Lee, H. Y. & Liou, J. P., Aug 2 2016, In : Expert Opinion on Investigational Drugs. 25, 8, p. 917-936 20 p.

Research output: Contribution to journalReview article

Tubulin Modulators
Microtubules
Clinical Trials
Taxoids
Neoplasms
6 Citations (Scopus)

Effect of C7-substitution of 1-arylsulfonyl-5-(N-hydroxyacrylamide)indolines on the selectivity towards a subclass of histone deacetylases

Lee, H. Y., Wang, L. T., Li, Y. H., Pan, S. L., Chen, Y. L., Teng, C. M. & Liou, J. P., Nov 28 2014, In : Organic and Biomolecular Chemistry. 12, 44, p. 8966-8976 11 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Tumors
Substitution reactions
selectivity
substitutes

Erratum to: A novel tubulin polymerization inhibitor, MPT0B206, downregulates Bcr-Abl expression and induces apoptosis in imatinib-sensitive and imatinib-resistant CML cells

Chen, C. W., Lee, Y. L., Liou, J. P., Liu, Y. H., Liu, C. W., Chen, T. Y. & Huan, H. M., Aug 18 2017, (Accepted/In press) In : Apoptosis. p. 1 1 p.

Research output: Contribution to journalArticle

Tubulin Modulators
Emitter coupled logic circuits
Apoptosis
Industry
Imatinib Mesylate
23 Citations (Scopus)

Hypoxia-induced downregulation of DUSP-2 phosphatase drives colon cancer stemness

Hou, P. C., Li, Y. H., Lin, S. C., Lin, S. C., Lee, J. C., Lin, B. W., Liou, J. P., Chang, J. Y., Kuo, C. C., Liu, Y. M., Sun, H. S. & Tsai, S. J., Aug 15 2017, In : Cancer Research. 77, 16, p. 4305-4316 12 p.

Research output: Contribution to journalArticle

Dual-Specificity Phosphatases
Dual Specificity Phosphatase 2
Colonic Neoplasms
Down-Regulation
Neoplasms
5 Citations (Scopus)
Autophagy
Colorectal Neoplasms
Cell Death
HCT116 Cells
Cyclin B1
32 Citations (Scopus)

Idiopathic pulmonary fibrosis: Current status, recent progress, and emerging targets

Liu, Y. M., Nepali, K. & Liou, J. P., Jan 26 2017, In : Journal of Medicinal Chemistry. 60, 2, p. 527-553 27 p.

Research output: Contribution to journalReview article

Idiopathic Pulmonary Fibrosis
Literature
Patents
Interstitial Lung Diseases
Therapeutics
17 Citations (Scopus)

Indole-3-ethylsulfamoylphenylacrylamides: Potent histone deacetylase inhibitors with anti-inflammatory activity

Mehndiratta, S., Hsieh, Y. L., Liu, Y. M., Wang, A. W., Lee, H. Y., Liang, L. Y., Kumar, S., Teng, C. M., Yang, C. R. & Liou, J. P., Oct 6 2014, In : European Journal of Medicinal Chemistry. 85, p. 468-479 12 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Histone Deacetylases
Cell Survival
Anti-Inflammatory Agents
Cells
3 Citations (Scopus)

Indole-3-ethylsulfamoylphenylacrylamides with potent anti-proliferative and anti-angiogenic activities

Mehndiratta, S., Pan, S. L., Kumar, S. & Liou, J. P., Jul 1 2016, In : Anti-Cancer Agents in Medicinal Chemistry. 16, 7, p. 907-913 7 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Acrylamide
Acrylamides
Neoplasms
Nude Mice
13 Citations (Scopus)

Intermediary metabolite precursor dimethyl-2-ketoglutarate stabilizes hypoxia-inducible factor-1α by inhibiting prolyl-4-hydroxylase PHD2

Hou, P., Kuo, C. Y., Cheng, C. T., Liou, J. P., Ann, D. K. & Chen, Q., Nov 24 2014, In : PLoS One. 9, 11, e113865.

Research output: Contribution to journalArticle

procollagen-proline dioxygenase
Prolyl Hydroxylases
Hypoxia-Inducible Factor 1
Metabolites
metabolites
4 Citations (Scopus)

In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells

Tsai, A. C., Pai, H. C., Wang, C. Y., Liou, J. P., Teng, C. M., Wang, J. C. & Pan, S. L., Jan 2014, In : British Journal of Pharmacology. 171, 1, p. 122-133 12 p.

Research output: Contribution to journalArticle

P-Glycoprotein
Non-Small Cell Lung Carcinoma
lissamine rhodamine B
Neoplasms
Cyclin B1
5 Citations (Scopus)

LTP-1, a novel antimitotic agent and Stat3 inhibitor, inhibits human pancreatic carcinomas in vitro and in vivo

Huang, H. L., Chao, M. W., Chen, C. C., Cheng, C. C., Chen, M. C., Lin, C. F., Liou, J. P., Teng, C. M. & Pan, S. L., Jun 9 2016, In : Scientific Reports. 6, 27794.

Research output: Contribution to journalArticle

Antimitotic Agents
Pancreatic Neoplasms
Polyploidy
Microtubules
Growth
2 Citations (Scopus)
Acrylamide
Colorectal Neoplasms
Histone Deacetylases
Cadherins
Neoplasms
4 Citations (Scopus)
Myeloid Cells
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Microtubules
Down-Regulation
Apoptosis
12 Citations (Scopus)

MPT0B098, a microtubule inhibitor, suppresses JAK2/STAT3 signaling pathway through modulation of SOCS3 stability in oral squamous cell carcinoma

Peng, H. Y., Cheng, Y. C., Hsu, Y. M., Wu, G. H., Kuo, C. C., Liou, J. P., Chang, J. Y., Jin, S. L. C. & Shiah, S. G., Jul 1 2016, In : PLoS One. 11, 7, e0158440.

Research output: Contribution to journalArticle

non-specific protein-tyrosine kinase
Janus Kinase 2
STAT3 Transcription Factor
squamous cell carcinoma
Microtubules
4 Citations (Scopus)
Tubulin Modulators
Myeloid Cells
Paclitaxel
Acute Myeloid Leukemia
Down-Regulation
5 Citations (Scopus)
Antineoplastic Agents
Ovarian Neoplasms
Cisplatin
Apoptosis
Pharmaceutical Preparations
1 Citation (Scopus)

MPT0G413, A novel HDAC6-selective inhibitor, and bortezomib synergistically exert anti-tumor activity in multiple myeloma cells

Huang, F. I., Wu, Y. W., Sung, T. Y., Liou, J. P., Lin, M. H., Pan, S. L. & Yang, C. R., Jan 1 2019, In : Frontiers in Oncology. 9, APR, p. 249 249.

Research output: Contribution to journalArticle

Open Access
Histone Deacetylases
Multiple Myeloma
Neoplasms
Histone Deacetylase Inhibitors
Growth
Open Access
Colorectal Neoplasms
Apoptosis
Ligands
Autophagy
Cell Death
3 Citations (Scopus)

MT-4 suppresses resistant ovarian cancer growth through targeting tubulin and HSP27

Pai, H. C., Kumar, S., Shen, C. C., Liou, J. P., Pan, S. L. & Che, M. T., Apr 14 2015, In : PLoS One. 10, 4, e0123819.

Research output: Contribution to journalArticle

ovarian neoplasms
Tubulin
tubulin
Ovarian Neoplasms
apoptosis
1 Citation (Scopus)

N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression

Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., Jan 1 2020, In : European Journal of Medicinal Chemistry. 185, p. 111725 111725.

Research output: Contribution to journalArticle

Anilides
HSP90 Heat-Shock Proteins
Histone Deacetylase Inhibitors
Histone Deacetylases
Down-Regulation
32 Citations (Scopus)

Nitro-Group-Containing Drugs

Nepali, K., Lee, H. Y. & Liou, J. P., Mar 28 2019, In : Journal of Medicinal Chemistry. 62, 6, p. 2851-2893 43 p.

Research output: Contribution to journalReview article

Antitubercular Agents
Antiparasitic Agents
Pharmaceutical Chemistry
Prodrugs
Therapeutic Uses
14 Citations (Scopus)

Novel histone deacetylase inhibitor MPT0G009 induces cell apoptosis and synergistic anticancer activity with tumor necrosis factor-related apoptosis-inducing ligand against human hepatocellular carcinoma

Chen, M-C., Huang, H-H., Lai, C-Y., Lin, Y-J., Liou, J-P., Lai, M-J., Li, Y-H., Teng, C-M. & Yang, C-R., Jan 5 2016, In : Oncotarget. 7, 1, p. 402-17 16 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Hepatocellular Carcinoma
Tumor Necrosis Factor-alpha
Apoptosis
Ligands
2 Citations (Scopus)

Novel microtubule inhibitor MPT0B098 inhibits hypoxia-induced epithelial-to-mesenchymal transition in head and neck squamous cell carcinoma

Tsai, I. T., Kuo, C. C., Liou, J. P. & Chang, J. Y., Mar 28 2018, In : Journal of Biomedical Science. 25, 1, 28.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Phosphorylation
Epithelial-Mesenchymal Transition
Transforming Growth Factors
Microtubules