Organization profile

Organisation profile

The TMU Research Center of Cancer Translational Medicine (RCCTM) is established through combining all cancer-related resources of TMU and its three affiliated hospitals. RCCTM is established with the goal of translating the research discoveries into state-of-the-art therapeutics for the prevention and treatment of cancer, as well as training future oncologists. We are committed to reduce the cancer burden through skilled, integrated and compassionate clinical care, and to eliminate the threat of cancer through research and education.

Fingerprint Dive into the research topics where RCCTM - Drug discovery is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Histone Deacetylases Medicine & Life Sciences
Histone Deacetylase Inhibitors Medicine & Life Sciences
Tubulin Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Heterografts Medicine & Life Sciences
Tubulin Modulators Medicine & Life Sciences
Growth Medicine & Life Sciences

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Projects 2014 2019

運用有機金屬偶聯反應於抗癌試劑合(2/2)

Liou, J.

8/1/187/1/19

Project: A - Government Institutionb - Ministry of Science and Technology

運用有機金屬偶聯反應於抗癌試劑合成(1/2)

Liou, J.

8/1/177/31/18

Project: A - Government Institutionb - Ministry of Science and Technology

Syntheses of Anti-Lung Cancer Agents(1/2)

Liou, J.

6/1/175/31/18

Project: A - Government Institutionb - Ministry of Science and Technology

Research Output 2014 2020

  • 700 Citations
  • 15 h-Index
  • 69 Article
  • 3 Review article
1 Citation (Scopus)

N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression

Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., Jan 1 2020, In : European Journal of Medicinal Chemistry. 185, p. 111725 111725.

Research output: Contribution to journalArticle

Anilides
HSP90 Heat-Shock Proteins
Histone Deacetylase Inhibitors
Histone Deacetylases
Down-Regulation

Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment

Kaur, N., Fang, Y. C., Lee, H. Y., Singh, A., Nepali, K., Lin, M. H., Yeh, T. K., Lai, M. J., Chan, L., Tu, Y. K., Banerjee, S., Hu, C. J. & Liou, J. P., Feb 1 2020, In : European Journal of Medicinal Chemistry. 187, 111915.

Research output: Contribution to journalArticle

Azepines
Histone Deacetylase Inhibitors
Blood Vessels
Acetylation
Acrylamide
5 Citations (Scopus)

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50