Organization profile

Organisation profile

The TMU Research Center of Cancer Translational Medicine (RCCTM) is established through combining all cancer-related resources of TMU and its three affiliated hospitals. RCCTM is established with the goal of translating the research discoveries into state-of-the-art therapeutics for the prevention and treatment of cancer, as well as training future oncologists. We are committed to reduce the cancer burden through skilled, integrated and compassionate clinical care, and to eliminate the threat of cancer through research and education.

Fingerprint Dive into the research topics where RCCTM - Drug discovery is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.

Histone Deacetylases Medicine & Life Sciences
Histone Deacetylase Inhibitors Medicine & Life Sciences
Tubulin Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Tubulin Modulators Medicine & Life Sciences
Apoptosis Medicine & Life Sciences
Heterografts Medicine & Life Sciences
Antineoplastic Agents Medicine & Life Sciences

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Projects 2014 2019

運用有機金屬偶聯反應於抗癌試劑合(2/2)

Liou, J.

8/1/187/1/19

Project: A - Government Institutionb - Ministry of Science and Technology

運用有機金屬偶聯反應於抗癌試劑合成(1/2)

Liou, J.

8/1/177/31/18

Project: A - Government Institutionb - Ministry of Science and Technology

Syntheses of Anti-Lung Cancer Agents(1/2)

Liou, J.

6/1/175/31/18

Project: A - Government Institutionb - Ministry of Science and Technology

Research Output 2014 2019

  • 584 Citations
  • 14 h-Index
  • 63 Article
  • 3 Review article
3 Citations (Scopus)

1-Arylsulfonyl indoline-benzamides as a new antitubulin agents, with inhibition of histone deacetylase

Lai, M. J., Ojha, R., Lin, M. H., Liu, Y. M., Lee, H. Y., Lin, T. E., Hsu, K. C., Chang, C. Y., Chen, M. C., Nepali, K., Chang, J. Y. & Liou, J. P., Jan 15 2019, In : European Journal of Medicinal Chemistry. 162, p. 612-630 19 p.

Research output: Contribution to journalArticle

Benzamides
Histone Deacetylases
Tubulin
Heterografts
Inhibitory Concentration 50
2 Citations (Scopus)

Anti-metastatic activity of MPT0G211, a novel HDAC6 inhibitor, in human breast cancer cells in vitro and in vivo

Hsieh, Y. L., Tu, H. J., Pan, S. L., Liou, J. P. & Yang, C. R., Jun 1 2019, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1866, 6, p. 992-1003 12 p.

Research output: Contribution to journalArticle

Triple Negative Breast Neoplasms
Histone Deacetylase Inhibitors
Breast Neoplasms
Histone Deacetylases
Acetylation
14 Citations (Scopus)

Nitro-Group-Containing Drugs

Nepali, K., Lee, H. Y. & Liou, J. P., Mar 28 2019, In : Journal of Medicinal Chemistry. 62, 6, p. 2851-2893 43 p.

Research output: Contribution to journalReview article

Antitubercular Agents
Antiparasitic Agents
Pharmaceutical Chemistry
Prodrugs
Therapeutic Uses