Ph.D. Program for Cancer Molecular Biology and Drug Discovery

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output 1996 2019

Filter
Review article
2019

Host immune response to anti-cancer camptothecin conjugated cyclodextrin-based polymers

Chen, Y. F., Wang, Y. H., Lei, C. S., Changou, C. A., Davis, M. E. & Yen, Y., Oct 23 2019, In : Journal of Biomedical Science. 26, 1, 1 p.

Research output: Contribution to journalReview article

Open Access
Camptothecin
Cyclodextrins
Polymers
Neoplasms
Nanoparticles
2 Citations (Scopus)

New paradigm of functional regulation by DNA mimic proteins: Recent updates

Wang, H. C., Chou, C. C., Hsu, K. C., Lee, C. H. & Wang, A. H. J., May 1 2019, In : IUBMB Life. 71, 5, p. 539-548 10 p.

Research output: Contribution to journalReview article

DNA
Charge distribution
Proteins
Clustered Regularly Interspaced Short Palindromic Repeats
Uracil-DNA Glycosidase

The role of ubiquitin-specific peptidases in cancer progression

Young, M. J., Hsu, K. C., Lin, T. E., Chang, W. C. & Hung, J. J., May 27 2019, In : Journal of Biomedical Science. 26, 1, 42.

Research output: Contribution to journalReview article

Open Access
Ubiquitin
Peptide Hydrolases
Ubiquitination
Neoplasms
Proteins
1 Citation (Scopus)
Open Access
biomarkers
Castration
Androgen Receptors
Biomarkers
Prostatic Neoplasms
2018

Bioactivity of Thyroid Hormone Analogs at Cancer Cells

Davis, P. J., Tang, H-Y., Hercbergs, A., Lin, H-Y., Keating, K. A. & Mousa, S. A., 2018, In : Frontiers in Endocrinology. 9, p. 739

Research output: Contribution to journalReview article

Thyroid Hormones
Thyronines
Thyroid Hormone Receptors
Integrins
Neoplasms
5 Citations (Scopus)

Contributions of thyroid hormone to cancer metastasis

Mousa, S. A., Glinsky, G. V., Lin, H. Y., Ashur-Fabian, O., Hercbergs, A., Keating, K. A. & Davis, P. J., Sep 1 2018, In : Biomedicines. 6, 3, 89.

Research output: Contribution to journalReview article

Open Access
Thyroid Hormones
Genes
Neoplasm Metastasis
Thyroxine
Neoplasms
6 Citations (Scopus)

Molecular Basis of Nongenomic Actions of Thyroid Hormone

Davis, P. J., Leonard, J. L., Lin, H. Y., Leinung, M. & Mousa, S. A., 2018, In : Vitamins and Hormones. p. 67-96

Research output: Contribution to journalReview article

Thyroid Hormone Receptors
Thyroid Hormones
Hormones
Protein Isoforms
Cell Membrane
2017
4 Citations (Scopus)

Biological mechanisms by which antiproliferative actions of resveratrol are minimized

Ho, Y., Lin, Y. S., Liu, H. L., Shih, Y. J., Lin, S. Y., Shih, A., Chin, Y. T., Chen, Y. R., Lin, H. Y. & Davis, P. J., Oct 1 2017, In : Nutrients. 9, 10, 1046.

Research output: Contribution to journalReview article

resveratrol
thyroid hormones
Thyroid Hormones
Polyphenols
neoplasms
12 Citations (Scopus)

Long non-coding RNA and tumor hypoxia: New players ushered toward an old arena

Shih, J. W. & Kung, H. J., Aug 8 2017, In : Journal of Biomedical Science. 24, 1, 53.

Research output: Contribution to journalReview article

Long Noncoding RNA
Tumors
Hypoxia-Inducible Factor 1
Tumor Biomarkers
Gene expression
7 Citations (Scopus)

Mechanisms of action of nonpeptide hormones on resveratrol-induced antiproliferation of cancer cells

Lin, H. Y., Hsieh, M. T., Cheng, G. Y., Lai, H. Y., Chin, Y. T., Shih, Y. J., Nana, A. W., Lin, S. Y., Yang, Y. C. S. H., Tang, H. Y., Chiang, I. J. & Wang, K., 2017, (Accepted/In press) In : Annals of the New York Academy of Sciences. p. 92-100

Research output: Contribution to journalReview article

Cells
Hormones
Neoplasms
Integrins
Phosphotransferases
9 Citations (Scopus)

Structural Insights into the Cytotoxic Mechanism of Vibrio parahaemolyticus PirAvp and PirBvp Toxins

Lin, S-J., Hsu, K-C. & Wang, H-C., Dec 1 2017, In : Marine Drugs. 15, 12

Research output: Contribution to journalReview article

Vibrio parahaemolyticus
Necrosis
Penaeidae
Agriculture
Aquaculture
9 Citations (Scopus)

Therapeutic applications of resveratrol and its derivatives on periodontitis

Chin, Y. T., Cheng, G. Y., Shih, Y. J., Lin, C. Y., Lin, S. J., Lai, H. Y., Whang-Peng, J., Chiu, H. C., Lee, S. Y., Fu, E., Tang, H. Y., Lin, H. Y. & Liu, L. F., Sep 1 2017, In : Annals of the New York Academy of Sciences. 1403, 1, p. 101-108 8 p.

Research output: Contribution to journalReview article

Periodontitis
Derivatives
Tissue
Signal transduction
Glucosides
2016
8 Citations (Scopus)

Actions of Thyroid Hormone Analogues on Chemokines

Davis, P. J., Glinsky, G. V., Lin, H. Y. & Mousa, S. A., 2016, In : Journal of Immunology Research. 2016, 3147671.

Research output: Contribution to journalReview article

Thyroid Hormones
Chemokines
Chemokine CX3CL1
Integrins
Brain
2 Citations (Scopus)

A new era for cancer target therapies: Applying systems biology and computer-aided drug design to cancer therapies

Wong, Y. H., Chiu, C. C., Lin, C. L., Chen, T. S., Jheng, B. R., Lee, Y. C., Chen, J. & Chen, B. S., Nov 1 2016, In : Current Pharmaceutical Biotechnology. 17, 14, p. 1246-1267 22 p.

Research output: Contribution to journalReview article

Computer-Aided Design
Systems Biology
Drug Design
Neoplasms
Ligands
7 Citations (Scopus)

Cul 3-KLHL20 ubiquitin ligase: Physiological functions, stress responses, and disease implications

Chen, H. Y., Liu, C. C. & Chen, R. H., 2016, In : Cell Division. 11, 1, 5.

Research output: Contribution to journalReview article

Physiological Stress
Ligases
Ubiquitin
Cullin Proteins
Substrates
22 Citations (Scopus)

Cullin 3 ubiquitin ligases in cancer biology: Functions and therapeutic implications

Chen, H. Y. & Chen, R. H., 2016, In : Frontiers in Oncology. 6, MAY, 113.

Research output: Contribution to journalReview article

Cullin Proteins
Ligases
Ubiquitin
Ubiquitin-Protein Ligases
Neoplasms
3 Citations (Scopus)

Possible contributions of thyroid hormone replacement to specific behaviors of cancer

Hercbergs, A., Davis, P. J., Lin, H. Y. & Mousa, S. A., Dec 1 2016, In : Biomedicine and Pharmacotherapy. 84, p. 655-659 5 p.

Research output: Contribution to journalReview article

Thyroid Hormones
Hypothyroidism
Neoplasms
Thyronines
Thyroxine
29 Citations (Scopus)

Thyroid Hormone, Cancer, and Apoptosis

Lin, H. Y., Chin, Y. T., Yang, Y. C. S. H., Lai, H. Y., Wang-Peng, J., Liu, L. F., Tang, H. Y. & Davis, P. J., Jun 13 2016, In : Comprehensive Physiology. 6, 3, p. 1221-1237 17 p.

Research output: Contribution to journalReview article

Thyroid Hormones
Thyroid Neoplasms
Apoptosis
Neoplasms
Integrin alpha Chains
22 Citations (Scopus)

Thyroid Hormone, Hormone Analogs, and Angiogenesis

Davis, P. J., Sudha, T., Lin, H. Y. & Mousa, S. A., Jan 1 2016, In : Comprehensive Physiology. 6, 1, p. 353-362 10 p.

Research output: Contribution to journalReview article

Thyroid Hormones
Hormones
Integrins
Growth Factor Receptors
Fibroblast Growth Factor 2
2015
16 Citations (Scopus)

Non-coding RNAs in castration-resistant prostate cancer: Regulation of androgen receptor signaling and cancer metabolism

Shih, J. W., Wang, L. Y., Hung, C. L., Kung, H. J. & Hsieh, C. L., Dec 4 2015, In : International Journal of Molecular Sciences. 16, 12, p. 28943-28978 36 p.

Research output: Contribution to journalReview article

Untranslated RNA
Castration
Androgen Receptors
metabolism
RNA
17 Citations (Scopus)

Overview of transforming growth factor β superfamily involvement in glioblastoma initiation and progression

Nana, A. W., Yang, P. M. & Lin, H. Y., 2015, In : Asian Pacific Journal of Cancer Prevention. 16, 16, p. 6813-6823 11 p.

Research output: Contribution to journalReview article

Transforming Growth Factors
Glioblastoma
Bone Morphogenetic Proteins
Growth Differentiation Factors
Activins
19 Citations (Scopus)

Thyroid hormone and anti-apoptosis in tumor cells

Lin, H. Y., Glinsky, G. V., Mousa, S. A. & Davis, P. J., 2015, In : Oncotarget. 6, 17, p. 14735-14743 9 p.

Research output: Contribution to journalReview article

Thyroid Hormones
Apoptosis
Neoplasms
Thyroxine
Integrins
13 Citations (Scopus)

Thyroid hormone and P-glycoprotein in tumor cells

Davis, P. J., Incerpi, S., Lin, H. Y., Tang, H. Y., Sudha, T. & Mousa, S. A., 2015, In : BioMed Research International. 2015, 168427.

Research output: Contribution to journalReview article

P-Glycoprotein
Thyroid Hormones
Tumors
Cells
Acidification
2014
47 Citations (Scopus)

Cancer cell gene expression modulated from plasma membrane integrin αvβ3 by thyroid hormone and nanoparticulate tetrac

Davis, P. J., Glinsky, G. V., Lin, H. Y., Leith, J. T., Hercbergs, A., Tang, H. Y., Ashur-Fabian, O., Incerpi, S. & Mousa, S. A., 2014, In : Frontiers in Endocrinology. 5, DEC, 240.

Research output: Contribution to journalReview article

Neoplasm Genes
Thyroid Hormones
Integrins
Cell Membrane
Gene Expression
16 Citations (Scopus)

Human DExD/H RNA helicases: Emerging roles in stress survival regulation

Shih, J. W. & Lee, Y. H. W., Sep 25 2014, In : Clinica Chimica Acta. 436, p. 45-58 14 p.

Research output: Contribution to journalReview article

RNA Helicases
RNA
Molecular Models
Cell death
Enzymes
14 Citations (Scopus)

Long non-coding RNA and epigenetic gene regulation of KSHV

Campbell, M., Kung, H. J. & Izumiya, Y., Nov 4 2014, In : Viruses. 6, 11, p. 4165-4177 13 p.

Research output: Contribution to journalReview article

Long Noncoding RNA
Human Herpesvirus 8
Epigenomics
Nuclear RNA
Genes
24 Citations (Scopus)

Nanotetrac targets integrin αvβ3 on tumor cells to disorder cell defense pathways and block angiogenesis

Davis, P. J., Lin, H. Y., Sudha, T., Yalcin, M., Tang, H. Y., Hercbergs, A., Leith, J. T., Luidens, M. K., Ashur-Fabian, O., Incerpi, S. & Mousa, S. A., 2014, In : OncoTargets and Therapy. 7, p. 1619-1624 6 p.

Research output: Contribution to journalReview article

Integrins
Hormones
Thyroid Hormones
Neoplasms
Thyronines
7 Citations (Scopus)

Recurrence of Differentiated Thyroid Carcinoma During Full TSH Suppression: Is the Tumor Now Thyroid Hormone Dependent?

Davis, P. J., Hercbergs, A., Luidens, M. K. & Lin, H. Y., 2014, In : Hormones and Cancer. 6, 1, p. 7-12 6 p.

Research output: Contribution to journalReview article

Thyroid Hormones
Thyroid Neoplasms
Recurrence
Follicular Adenocarcinoma
Neoplasms
12 Citations (Scopus)

Sumo and kshv replication

Chang, P. C. & Kung, H. J., Jan 1 2014, In : Cancers. 6, 4, p. 1905-1924 20 p.

Research output: Contribution to journalReview article

Ubiquitin
Human Herpesvirus 8
Sumoylation
Herpesviridae
Viral Proteins
22 Citations (Scopus)

The functions and regulations of DAPK in cancer metastasis

Chen, H. Y., Lee, Y. R. & Chen, R. H., Feb 2014, In : Apoptosis. 19, 2, p. 364-370 7 p.

Research output: Contribution to journalReview article

Death-Associated Protein Kinases
Neoplasm Metastasis
Neoplasms
Cell Death
Cell death
2013
21 Citations (Scopus)

Adjunctive input to the nuclear thyroid hormone receptor from the cell surface receptor for the hormone

Davis, P. J., Lin, H. Y., Tang, H. Y., Davis, F. B. & Mousa, S. A., Dec 1 2013, In : Thyroid. 23, 12, p. 1503-1509 7 p.

Research output: Contribution to journalReview article

Thyroid Hormone Receptors
Cell Surface Receptors
Cytoplasmic and Nuclear Receptors
CD3 Antigens
Co-Repressor Proteins
6 Citations (Scopus)

Human papillomavirus and non-small cell lung cancer

Hsu, N. Y., Lee, H., Yen, Y. & Cheng, Y. W., Nov 2013, In : Thoracic Cancer. 4, 4, p. 345-353 9 p.

Research output: Contribution to journalReview article

Non-Small Cell Lung Carcinoma
Papillomavirus Infections
Lung Neoplasms
Carcinogenesis
p16 Genes
3 Citations (Scopus)

Identification of novel mutations of TP53, ALK and RET gene in metastatic thymic squamous cell carcinoma and its therapeutic implication

Hu, Z., Wang, J., Yao, T., Hong, R. L., Zhang, K., Gao, H., Wu, X., Li, J., Bai, C. & Yen, Y., Jul 1 2013, In : Lung Cancer. 81, 1, p. 27-31 5 p.

Research output: Contribution to journalReview article

Thymus Neoplasms
Squamous Cell Carcinoma
Mutation
Neoplasm Genes
Genes
17 Citations (Scopus)

Small Molecule Hormone or Hormone-Like Ligands of Integrin αVβ3: Implications for Cancer Cell Behavior

Davis, P. J., Mousa, S. A., Cody, V., Tang, H. Y. & Lin, H. Y., Dec 2013, In : Hormones and Cancer. 4, 6, p. 335-342 8 p.

Research output: Contribution to journalReview article

Integrins
Hormones
Ligands
Thyroid Hormone Receptors
Neoplasms
2009

Nongenomic Actions of Thyroid Hormone Initiated at the Plasma Membrane or in Cytoplasm

Davis, P. J., Davis, F. B., Lin, H-Y., Hercbergs, A. & Mousa, S. A., 2009, In : Hot Thyroidology.

Research output: Contribution to journalReview article

Thyroid Hormones
Integrins
Cytoplasm
Cell Membrane
Hormones