Ph.D. Program for Cancer Molecular Biology and Drug Discovery

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output 1996 2020

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6 Citations (Scopus)

Resveratrol inhibits human leiomyoma cell proliferation via crosstalk between integrin αvβ3 and IGF-1R

Ho, Y., SH Yang, Y. C., Chin, Y. T., Chou, S. Y., Chen, Y. R., Shih, Y. J., Whang-Peng, J., Changou, C. A., Liu, H. L., Lin, S. J., Tang, H. Y., Lin, H. Y. & Davis, P. J., Oct 1 2018, In : Food and Chemical Toxicology. 120, p. 346-355 10 p.

Research output: Contribution to journalArticle

resveratrol
integrins
Myoma
Cell proliferation
somatomedins
8 Citations (Scopus)

Resveratrol inhibits proliferation of myometrial and leiomyoma cells and decreases extracellular matrix-associated protein expression

Wu, C. H., Shieh, T. M., Wei, L. H., Cheng, T. F., Chen, H. Y., Huang, T. C., Wang, K. L. & Hsia, S. M., May 1 2016, In : Journal of Functional Foods. 23, p. 241-252 12 p.

Research output: Contribution to journalArticle

Extracellular Matrix Proteins
resveratrol
Leiomyoma
extracellular matrix
smooth muscle

Ribonucleotide reductase and non-small cell lung cancer

Hsu, N. Y., Lee, H., Cheng, Y. W. & Yen, Y., Jan 1 2012, In : Chinese Journal of Lung Cancer. 15, 11, p. 619-623 5 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Non-Small Cell Lung Carcinoma
13 Citations (Scopus)

Ribonucleotide Reductase Large Subunit M1 Predicts Poor Survival Due to Modulation of Proliferative and Invasive Ability of Gastric Cancer

Wang, Q., Liu, X., Zhou, J., Huang, Y., Zhang, S., Shen, J., Loera, S., Yuan, X., Chen, W., Jin, M., Shibata, S., Liu, Y., Chu, P., Wang, L. & Yen, Y., Jul 29 2013, In : PLoS One. 8, 7, e70191.

Research output: Contribution to journalArticle

ribonucleotide reductase
Ribonucleotide Reductases
stomach neoplasms
Stomach Neoplasms
Modulation

Ribonucleotide reductase subunit M2B deficiency leads to mitochondrial permeability transition pore opening and is associated with aggressive clinicopathologic manifestations of breast cancer

Xue, L., Liu, X., Wang, Q., Liu, C. Q., Chen, Y., Jia, W., Hsie, R., Chen, Y., Luh, F., Zheng, S. & Yen, Y., Jan 1 2018, In : American Journal of Translational Research. 10, 11, p. 3635-3649 15 p., AJTR0084684.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Breast Neoplasms
KB Cells
Spermine
MCF-7 Cells
12 Citations (Scopus)

Ring fusion strategy for synthesis and lead optimization of sulfur-substituted anthra[1,2-c[[1,2,5]thiadiazole-6,11-dione derivatives as promising scaffold of antitumor agents

Lee, Y. R., Chen, T. C., Lee, C. C., Chen, C. L., Ahmed Ali, A. A., Tikhomirov, A., Guh, J. H., Yu, D. S. & Huang, H. S., Sep 18 2015, In : European Journal of Medicinal Chemistry. 102, p. 661-676 16 p.

Research output: Contribution to journalArticle

Sulfur
Scaffolds
Antineoplastic Agents
Fusion reactions
Apoptosis
13 Citations (Scopus)

Ring fusion strategy for the synthesis of anthra[2,3-d ]oxazole-2-thione-5,10-dione homologues as DNA topoisomerase inhibitors and as antitumor agents

Chen, C. L., Liu, F. L., Lee, C. C., Chen, T. C., Chang, W. W., Guh, J. H., Ahmed Ali, A. A., Chang, D. M. & Huang, H. S., Nov 24 2014, In : European Journal of Medicinal Chemistry. 87, p. 30-38 9 p.

Research output: Contribution to journalArticle

Topoisomerase Inhibitors
Oxazoles
Thiones
Type I DNA Topoisomerase
Antineoplastic Agents

RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene transcription

Yang, C. P., Kuo, Y. L., Lee, Y. C., Lee, K. H., Chiang, C. W., Wang, J. M., Hsu, C. C., Chang, W. C. & Lin, D. Y., Sep 16 2016, In : Biochemical and Biophysical Research Communications. 478, 2, p. 873-880 8 p.

Research output: Contribution to journalArticle

Transcription
Genes
Proteins
Ribosomal DNA
Ribosomes
3 Citations (Scopus)

Risk analysis of malignant potential of oral verrucous hyperplasia: A follow-up study of 269 patients and copy number variation analysis

Wu, M. H., Luo, J. D., Wang, W. C., Chang, T. H., Hwang, W. L., Lee, K. H., Liu, S. Y., Yang, J. W., Chiou, C. T., Chang, C. H. & Chiang, W. F., Jan 1 2018, (Accepted/In press) In : Head and Neck.

Research output: Contribution to journalArticle

Hyperplasia
Oral Submucous Fibrosis
Mastication
Survival Rate
Gene Amplification
2 Citations (Scopus)

Risk of fracture in transfusion-naïve thalassemia population: A nationwide population-based retrospective cohort study

Chen, Y. G., Lu, C. S., Lin, T. Y., Lin, C. L., Tzeng, H. E. & Tsai, C. H., Jan 1 2018, In : Bone. 106, p. 121-125 5 p.

Research output: Contribution to journalArticle

Thalassemia
Cohort Studies
Retrospective Studies
Population
Control Groups

Rrm2b deletion causes mitochondrial metabolic defects in renal tubules

Chen, Y. F., Lin, I. H., Guo, Y. R., Chiu, W. J., Wu, M. S., Jia, W. & Yen, Y., Sep 13 2019, In : Scientific Reports. 9, 1, 1 p.

Research output: Contribution to journalArticle

Open Access
Kidney
Mitochondria
Kidney Diseases
DNA Replication
Knockout Mice
7 Citations (Scopus)

RRM2B-mediated regulation of mitochondrial activity and inflammation under oxidative stress

Cho, E. C., Kuo, M. L., Cheng, J. H., Cheng, Y. C., Hsieh, Y. C., Liu, Y. R., Hsieh, R. H. & Yen, Y., 2015, In : Mediators of Inflammation. 2015, 287345.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Oxidative Stress
Inflammation
Mitochondrial Genes
DNA Damage
21 Citations (Scopus)

RRM2B suppresses activation of the oxidative stress pathway and is Up-regulated by P53 during senescence

Kuo, M. L., Sy, A. J., Xue, L., Chi, M., Michelle, M. T., Yen, T., Chiang, M. I., Chang, L., Chu, P. & Yen, Y., Nov 22 2012, In : Scientific Reports. 2, 822.

Research output: Contribution to journalArticle

Oxidative Stress
Fibroblasts
Prostatic Intraepithelial Neoplasia
Deoxyribonucleosides
Ribonucleotide Reductases
27 Citations (Scopus)

S-adenosyl-L-methionine-competitive inhibitors of the histone methyltransferase EZH2 induce autophagy and enhance drug sensitivity in cancer cells

Liu, T. P., Lo, H. L., Wei, L. S., Hsiao, H. H. Y. & Yang, P. M., 2015, In : Anti-Cancer Drugs. 26, 2, p. 139-147 9 p.

Research output: Contribution to journalArticle

S-Adenosylmethionine
Autophagy
Pharmaceutical Preparations
Neoplasms
Antineoplastic Agents
15 Citations (Scopus)

SCP phosphatases suppress renal cell carcinoma by stabilizing PML and inhibiting mTOR/HIF signaling

Lin, Y. C., Lu, L. T., Chen, H. Y., Duan, X., Lin, X., Feng, X. H., Tang, M. J. & Chen, R. H., Dec 1 2014, In : Cancer Research. 74, 23, p. 6935-6946 12 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Phosphoric Monoester Hydrolases
Leukemia
Neoplasms
Down-Regulation
7 Citations (Scopus)

Selective recognition and stabilization of new ligands targeting the potassium form of the human telomeric G-quadruplex DNA

Lin, Y. H., Chuang, S. M., Wu, P. C., Chen, C. L., Jeyachandran, S., Lo, S. C., Huang, H. S. & Hou, M. H., Aug 11 2016, In : Scientific Reports. 6, 31019.

Research output: Contribution to journalArticle

Potassium
Stabilization
Ligands
DNA
Anthraquinones
19 Citations (Scopus)

Signature miRNAs in colorectal cancers were revealed using a bias reduction small RNA deep sequencing protocol

Sun, G., Cheng, Y. W., Lai, L., Huang, T. C., Wang, J., Wu, X., Wang, Y., Huang, Y., Wang, J., Zhang, K., Hu, S., Yang, J. R. & Yen, Y., 2016, In : Oncotarget. 7, 4, p. 3857-3872 16 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
High-Throughput Nucleotide Sequencing
MicroRNAs
Colorectal Neoplasms
Rectal Neoplasms
3 Citations (Scopus)

Significance of cyclin D1 overexpression in progression and radio-resistance of pediatric ependymomas

Liang, M. L., Hsieh, T. H., Liu, Y. R., Chen, Y. W., Lee, Y. Y., Chang, F. C., Lin, S. C., Huang, M. C., Ho, D. M. T., Wong, T-T., Yen, Y. & Yang, M. H., Jan 1 2018, In : Oncotarget. 9, 2, p. 2527-2542 16 p.

Research output: Contribution to journalArticle

Ependymoma
Cyclin D1
Radio
Pediatrics
DNA Repair
49 Citations (Scopus)

Silencing of miR-124 induces neuroblastoma SK-N-SH cell differentiation, cell cycle arrest and apoptosis through promoting AHR

Huang, T. C., Chang, H. Y., Chen, C. Y., Wu, P. Y., Lee, H., Liao, Y. F., Hsu, W. M., Huang, H. C. & Juan, H. F., Nov 16 2011, In : FEBS Letters. 585, 22, p. 3582-3586 5 p.

Research output: Contribution to journalArticle

Aryl Hydrocarbon Receptors
Cell Cycle Checkpoints
Neuroblastoma
Cell Differentiation
Cells
6 Citations (Scopus)

Simvastatin inhibits cell proliferation and migration in human anaplastic thyroid cancer

Chen, M. C., Tsai, Y. C., Tseng, J. H., Liou, J. J., Horng, S., Wen, H. C., Fan, Y. C., Zhong, W. B. & Hsu, S. P., Dec 13 2017, In : International Journal of Molecular Sciences. 18, 12, 2690.

Research output: Contribution to journalArticle

Simvastatin
Cell proliferation
Cell Movement
cancer
Cell Proliferation
56 Citations (Scopus)

Sirtuin 7 plays a role in ribosome biogenesis and protein synthesis

Tsai, Y. C., Greco, T. M. & Cristea, I. M., 2014, In : Molecular and Cellular Proteomics. 13, 1, p. 73-83 11 p.

Research output: Contribution to journalArticle

Transcription
Ribosomes
Transfer RNA
Ribosomal DNA
Purification
13 Citations (Scopus)

Sphere-Formation Assay: Three-dimensional in vitro culturing of prostate cancer stem/Progenitor sphere-forming cells

Bahmad, H. F., Cheaito, K., Chalhoub, R. M., Hadadeh, O., Monzer, A., Ballout, F., El-Hajj, A., Mukherji, D., Liu, Y. N., Daoud, G. & Abou-Kheir, W., Aug 28 2018, In : Frontiers in Oncology. 8, AUG, 347.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Prostatic Neoplasms
Neoplasms
Castration
In Vitro Techniques
10 Citations (Scopus)

Spontaneous and vaccine-induced clearance of Mus musculus papillomavirus 1 infection

Jiang, R. T., Wang, J. W., Peng, S., Huang, T. C., Wang, C., Cannella, F., Chang, Y. N., Viscidi, R. P., Best, S. R. A., Hung, C. F. & Roden, R. B. S., Aug 1 2017, In : Journal of Virology. 91, 15, e00699-17.

Research output: Contribution to journalArticle

Papillomavirus Infections
Papillomaviridae
Mus musculus
papilloma
Papilloma
4 Citations (Scopus)

Sterol O-acyltransferase 2 contributes to the yolk cholesterol trafficking during zebrafish embryogenesis

Chang, N. Y., Chan, Y. J., Ding, S. T., Lee, Y. H., Huangfu, W. C. & Liu, I. H., Dec 1 2016, In : PLoS One. 11, 12, e0167644.

Research output: Contribution to journalArticle

cholesterol acyltransferase
Zebrafish
Danio rerio
Embryonic Development
embryogenesis
3 Citations (Scopus)

Structural insights to the heterotetrameric interaction between the vibrio parahaemolyticus pirA vp and pirB vp toxins and activation of the cry-like pore-forming domain

Lin, S. J., Chen, Y. F., Hsu, K. C., Chen, Y. L., Ko, T. P., Lo, C. F., Wang, H. C. & Wang, H. C., Apr 1 2019, In : Toxins. 11, 4, 233.

Research output: Contribution to journalArticle

Open Access
Vibrio parahaemolyticus
Penaeidae
Chemical activation
Necrosis
Hepatopancreas
17 Citations (Scopus)

Structure-based hybridization, synthesis and biological evaluation of novel tetracyclic heterocyclic azathioxanthone analogues as potential antitumor agents

Chen, T. C., Wu, C. L., Lee, C. C., Chen, C. L., Yu, D. S. & Huang, H. S., Oct 20 2015, In : European Journal of Medicinal Chemistry. 103, p. 615-627 13 p.

Research output: Contribution to journalArticle

Antineoplastic Agents
Inhibitory Concentration 50
Assays
Cytostatic Agents
Caspase 3
13 Citations (Scopus)

Suppression of pancreatic cancer by sulfated non-anticoagulant low molecular weight heparin

Sudha, T., Yalcin, M., Lin, H. Y., Elmetwally, A. M., Nazeer, T., Arumugam, T., Phillips, P. & Mousa, S. A., Aug 1 2014, In : Cancer Letters. 350, 1-2, p. 25-33 9 p.

Research output: Contribution to journalArticle

Low Molecular Weight Heparin
Pancreatic Neoplasms
Heparin
gemcitabine
Neoplasms
Open Access
Minimally Invasive Surgical Procedures
Robotics
Rectal Neoplasms
Neoplasms
Length of Stay
32 Citations (Scopus)

Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in liver cancer cells in vitro and in vivo

Chen, C. H., Chen, M. C., Wang, J. C., Tsai, A. C., Chen, C. S., Liou, J. P., Pan, S. L. & Teng, C. M., 2014, In : Clinical Cancer Research. 20, 5, p. 1274-1287 14 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Liver Neoplasms
Heterografts
Cell Survival
Histone Code
47 Citations (Scopus)

Synthesis and biological evaluation of 1-arylsulfonyl-5-(N -hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo

Lai, M. J., Huang, H. L., Pan, S. L., Liu, Y. M., Peng, C. Y., Lee, H. Y., Yeh, T. K., Huang, P. H., Teng, C. M., Chen, C. S., Chuang, H. Y. & Liou, J. P., Apr 26 2012, In : Journal of Medicinal Chemistry. 55, 8, p. 3777-3791 15 p.

Research output: Contribution to journalArticle

Indoles
Histone Deacetylase Inhibitors
Heterografts
Isoenzymes
Cell Line

Synthesis and biological evaluation of anthra[1,9-cd]pyrazol-6(2H)-one scaffold derivatives as potential anticancer agents

Chen, T. C., Guh, J. H., Hsu, H. W., Chen, C. L., Lee, C. C., Wu, C. L., Lee, Y. R., Lin, J. J., Yu, D. S. & Huang, H. S., 2015, In : Arabian Journal of Chemistry.

Research output: Contribution to journalArticle

Scaffolds
Antineoplastic Agents
Cells
Derivatives
losoxantrone
1 Citation (Scopus)

Synthesis and evaluation of new 3-substituted-4-chloro-thioxanthone derivatives as potent anti-breast cancer agents

Chen, C. L., Chen, T. C., Lee, C. C., Shih, L. C., Lin, C. Y., Hsieh, Y. Y., Ali, A. A. A. & Huang, H. S., 2015, In : Arabian Journal of Chemistry.

Research output: Contribution to journalArticle

Cells
Derivatives
thioxanthone
Screening
Molecules
5 Citations (Scopus)

Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: Identification of functional disparities between azacytidine and decitabine

Hsieh, Y. Y., Huang, T. C., Lo, H. L., Jhan, J. Y., Chen, S. T. & Yang, P. M., May 10 2016, In : Oncotarget. 7, 19, p. 27363-27378 16 p.

Research output: Contribution to journalArticle

decitabine
Azacitidine
Drug Discovery
Genomics
Polypharmacology
2 Citations (Scopus)

Systematic polypharmacology and drug repurposing via an integrated L1000-based Connectivity Map database mining

Liu, T. P., Hsieh, Y. Y., Chou, C. J. & Yang, P. M., Nov 1 2018, In : Royal Society Open Science. 5, 11, 181321.

Research output: Contribution to journalArticle

Polypharmacology
Drug Repositioning
Databases
Pharmaceutical Preparations
Topoisomerase Inhibitors
17 Citations (Scopus)

Targeted delivery of cisplatin to tumor xenografts via the nanoparticle component of nano-diamino-tetrac

Sudha, T., Bharali, D. J., Yalcin, M., Darwish, N. H. E., Coskun, M. D., Keating, K. A., Lin, H. Y., Davis, P. J. & Mousa, S. A., Feb 1 2017, In : Nanomedicine. 12, 3, p. 195-205 11 p.

Research output: Contribution to journalArticle

Heterografts
tumor
Nanoparticles
Cisplatin
Tumors
13 Citations (Scopus)

Targeted delivery of paclitaxel and doxorubicin to cancer xenografts via the nanoparticle of nano-diamino-tetrac

Sudha, T., Bharali, D. J., Yalcin, M., Darwish, N. H. E., Coskun, M. D., Keating, K. A., Lin, H. Y., Davis, P. J. & Mousa, S. A., Feb 15 2017, In : International Journal of Nanomedicine. 12, p. 1305-1315 11 p.

Research output: Contribution to journalArticle

Paclitaxel
Heterografts
Nanoparticles
Doxorubicin
Drug delivery
1 Citation (Scopus)
Open Access
Autophagy
Fibroblast Growth Factor Receptors
Neoplasms
Drug Combinations
gemcitabine
5 Citations (Scopus)

Targeting galectin-1 impairs castration-resistant prostate cancer progression and invasion

Shih, T-C., Liu, R., Wu, C-T., Li, X., Xiao, W., Deng, X., Kiss, S., Wang, T., Chen, X-J., Carney, R., Kung, H-J., Duan, Y., Ghosh, P. M. & Lam, K. S., 2018, In : Clinical Cancer Research. 24, 17, p. 4319-4331 13 p.

Research output: Contribution to journalArticle

Galectin 1
Castration
Prostatic Neoplasms
Androgen Receptors
docetaxel
6 Citations (Scopus)

Targeting insulin-like growth factor-binding protein-3 by microRNA-125b promotes tumor invasion and poor outcomes in non-small-cell lung cancer

Wang, H. H., Wang, Y. C., Wu, D-W., Hung, C. S., Chen, C. Y. & Lee, H., Apr 1 2017, In : Tumor Biology. 39, 4

Research output: Contribution to journalArticle

Insulin-Like Growth Factor Binding Protein 3
MicroRNAs
Non-Small Cell Lung Carcinoma
Phosphatidylinositol 3-Kinases
Neoplasms
23 Citations (Scopus)

Targeting of multiple oncogenic signaling pathways by Hsp90 inhibitor alone or in combination with berberine for treatment of colorectal cancer

Su, Y-H., Tang, W. C., Cheng, Y. W., Sia, P., Huang, C. C., Lee, Y. C., Jiang, H. Y., Wu, M. H., Lai, I. L., Lee, J. W. & Lee, K. H., Oct 1 2015, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1853, 10, p. 2261-2272 12 p.

Research output: Contribution to journalArticle

Berberine
HSP90 Heat-Shock Proteins
Colorectal Neoplasms
Chemical Databases
Catenins
69 Citations (Scopus)

Targeting therapy for breast carcinoma by ATP synthase inhibitor aurovertin b

Huang, T. C., Chang, H. Y., Hsu, C. H., Kuo, W. H., Chang, K. J. & Juan, H. F., Apr 2008, In : Journal of Proteome Research. 7, 4, p. 1433-1444 12 p.

Research output: Contribution to journalArticle

Aurovertins
Adenosine Triphosphate
Cells
Breast Neoplasms
Tumors
8 Citations (Scopus)
T Cell Transcription Factor 1
Androgen Receptors
MicroRNAs
Androgens
Prostatic Neoplasms
12 Citations (Scopus)

TC-N19, a novel dual inhibitor of EGFR and cMET, efficiently overcomes EGFR-TKI resistance in non-small-cell lung cancer cells

Wu, D. W., Chen, T. C., Huang, H. S. & Lee, H., Jun 30 2016, In : Cell death & disease. 7, 6, p. e2290

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Paxillin
Heterografts
7 Citations (Scopus)

Ten-eleven translocation 1 (TET1) gene is a potential target of miR-21-5p in human colorectal cancer

Cheng, Y. W., Chou, C. J. & Yang, P. M., Mar 1 2018, In : Surgical Oncology. 27, 1, p. 76-81 6 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
5-Methylcytosine
Genes
3' Untranslated Regions
DNA Methylation
1 Citation (Scopus)

Tetrac and NDAT Induce Anti-proliferation via Integrin αvβ3 in Colorectal Cancers With Different K-RAS Status

Chin, Y-T., He, Z-R., Chen, C-L., Chu, H-C., Ho, Y., Su, P-Y., Yang, Y-C. S. H., Wang, K., Shih, Y-J., Chen, Y-R., Pedersen, J. Z., Incerpi, S., Nana, A. W., Tang, H-Y., Lin, H-Y., Mousa, S. A., Davis, P. J. & Whang-Peng, J., Jan 1 2019, In : Frontiers in Endocrinology. 10, APR, p. 130 130.

Research output: Contribution to journalArticle

Integrins
Colorectal Neoplasms
HCT116 Cells
Neoplasms
HT29 Cells
12 Citations (Scopus)

Tetrac downregulates β-catenin and HMGA2 to promote the effect of resveratrol in colon cancer

Nana, A. W., Chin, Y. T., Lin, C. Y., Ho, Y., Bennett, J. A., Shih, Y. J., Chen, Y. R., Changou, C. A., Pedersen, J. Z., Incerpi, S., Liu, L. F., Whang-Peng, J., Fu, E., Li, W. S., Mousa, S. A., Lin, H. Y. & Davis, P. J., Mar 1 2018, In : Endocrine-Related Cancer. 25, 3, p. 279-293 15 p.

Research output: Contribution to journalArticle

High Mobility Group Proteins
Catenins
varespladib methyl
Colonic Neoplasms
Down-Regulation
2 Citations (Scopus)

The Ambivalent Role of lncRNA Xist in Carcinogenesis

Chen, Y. K. & Yen, Y., Apr 15 2019, In : Stem Cell Reviews and Reports. 15, 2, p. 314-323 10 p.

Research output: Contribution to journalArticle

Long Noncoding RNA
X Chromosome Inactivation
Carcinogenesis
Neoplasms
X Chromosome
3 Citations (Scopus)

The anticancer effects of MPT0G211, a novel HDAC6 inhibitor, combined with chemotherapeutic agents in human acute leukemia cells

Tu, H. J., Lin, Y. J., Chao, M. W., Sung, T. Y., Wu, Y. W., Chen, Y. Y., Lin, M. H., Liou, J. P., Pan, S. L. & Yang, C. R., Dec 29 2018, In : Clinical Epigenetics. 10, 1, 162.

Research output: Contribution to journalArticle

Leukemia
Vincristine
Doxorubicin
Drug Therapy
Neoplasms
8 Citations (Scopus)

The antiparasitic drug niclosamide inhibits dengue virus infection by interfering with endosomal acidification independent of mTOR

Kao, J. C., HuangFu, W. C., Tsai, T. T., Ho, M. R., Jhan, M. K., Shen, T. J., Tseng, P. C., Wang, Y. T. & Lin, C. F., Aug 1 2018, In : PLoS Neglected Tropical Diseases. 12, 8, e0006715.

Research output: Contribution to journalArticle

Niclosamide
Antiparasitic Agents
Dengue Virus
Virus Diseases
Sirolimus
11 Citations (Scopus)

The APE1 Asp/Asp genotype and the combination of APE1 Asp/Asp and hOGG1-Cys variants are associated with increased p53 mutation in non-small cell lung cancer

Lin, C. H., Chen, P. M., Cheng, Y. W., Chen, C. Y., Yuan, C. J. & Lee, H., 2012, In : Journal of Epidemiology. 22, 6, p. 537-542 6 p.

Research output: Contribution to journalArticle

Viperidae
Non-Small Cell Lung Carcinoma
Genotype
Lung Neoplasms
Mutation