Ph.D. Program for Cancer Molecular Biology and Drug Discovery

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output 1996 2020

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2014
14 Citations (Scopus)

Increased levels of circulating advanced glycation end-products in menopausal women with osteoporosis

Yang, D. H., Chiang, T. I., Chang, I. C., Lin, F. H., Wei, C. C. & Cheng, Y. W., 2014, In : International Journal of Medical Sciences. 11, 4, p. 453-460 8 p.

Research output: Contribution to journalArticle

Advanced Glycosylation End Products
Osteoporosis
Metabolic Bone Diseases
Serum
Bone and Bones
4 Citations (Scopus)

In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells

Tsai, A. C., Pai, H. C., Wang, C. Y., Liou, J. P., Teng, C. M., Wang, J. C. & Pan, S. L., Jan 2014, In : British Journal of Pharmacology. 171, 1, p. 122-133 12 p.

Research output: Contribution to journalArticle

P-Glycoprotein
Non-Small Cell Lung Carcinoma
lissamine rhodamine B
Neoplasms
Cyclin B1

Jejunal Cancer with WRN Mutation Identified from Next-Generation Sequencing: A Case Study and Minireview

Chang, C., Shiah, H-S., Hsu, N-Y., Huang, H. Y., Chu, J-S. & Yen, Y., 2014, In : Case Reports in Surgery.

Research output: Contribution to journalArticle

Jejunal Neoplasms
Jejunum
Mutation
Small Intestine
Exome
17 Citations (Scopus)

LKB1 Loss at Transcriptional Level Promotes Tumor Malignancy and Poor Patient Outcomes in Colorectal Cancer

He, T. Y., Tsai, L. H., Huang, C. C., Chou, M. C. & Lee, H., 2014, In : Annals of Surgical Oncology. 21, 4, p. 703-710 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Phosphotransferases
Liver
Neoplasms
Sirolimus
19 Citations (Scopus)

LKB1 loss by alteration of the NKX2-1/p53 pathway promotes tumor malignancy and predicts poor survival and relapse in lung adenocarcinomas

Tsai, L. H., Chen, P. M., Cheng, Y. W., Chen, C. Y., Sheu, G. T., Wu, T. C. & Lee, H., Jul 17 2014, In : Oncogene. 33, 29, p. 3851-3860 10 p.

Research output: Contribution to journalArticle

Recurrence
Survival
Neoplasms
Adenocarcinoma of lung
Lung
36 Citations (Scopus)

Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance

Siu, M. K., Abou-Kheir, W., Yin, J. J., Chang, Y. S., Barrett, B., Suau, F., Casey, O., Chen, W. Y., Fang, L., Hynes, P., Hsieh, Y. Y., Liu, Y. N., Huang, J. & Kelly, K., 2014, In : Oncotarget. 5, 11, p. 3770-3784 15 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Protein-Tyrosine Kinases
Prostatic Neoplasms
Neoplasm Metastasis
Apoptosis Regulatory Proteins
16 Citations (Scopus)

Low/negative expression of DDX3 might predict poor prognosis in non-smoker patients with oral cancer

Lee, C. H., Lin, S. H., Yang, S. F., Yang, S. M., Chen, M. K., Lee, H., Ko, J. L., Chen, C. J. & Yeh, K. T., Jan 2014, In : Oral Diseases. 20, 1, p. 76-83 8 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Squamous Cell Carcinoma
Neoplasms
Survival
Mastication
36 Citations (Scopus)

Metabolism and mis-metabolism of the neuropathological signature protein TDP-43

Huang, C. C., Bose, J. K., Majumder, P., Lee, K. H., Huang, J. T. J., Huang, J. K. & Shen, C. K. J., 2014, In : Journal of Cell Science. 127, 14, p. 3024-3038 15 p.

Research output: Contribution to journalArticle

TDP-43 Proteinopathies
Autophagy
Caspases
Frontotemporal Lobar Degeneration
Proteins
49 Citations (Scopus)

MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo

Hsu, T. I., Hsu, C. H., Lee, K. H., Lin, J. T., Chen, C. S., Chang, K. C., Su, C. Y. J., Hsiao, M. & Lu, P. J., Jan 1 2014, In : Oncogenesis. 3, 4, e99.

Research output: Contribution to journalArticle

Protein-Serine-Threonine Kinases
MicroRNAs
Prostatic Neoplasms
Carcinogenesis
Neoplasms
26 Citations (Scopus)

MicroRNA-21 promotes tumour malignancy via increased nuclear translocation of β-catenin and predicts poor outcome in APC-mutated but not in APC-wild-type colorectal cancer

Lin, P. L., Wu, D. W., Huang, C. C., He, T. Y., Chou, M. C., Sheu, G. T. & Lee, H., Oct 1 2014, In : Carcinogenesis. 35, 10, p. 2175-2182 8 p.

Research output: Contribution to journalArticle

Catenins
Adenomatous Polyposis Coli
MicroRNAs
Colorectal Neoplasms
Neoplasms
34 Citations (Scopus)

MicroRNA-224 suppresses colorectal cancer cell migration by targeting Cdc42

Ke, T. W., Hsu, H. L., Wu, Y. H., Chen, W. T. L., Cheng, Y. W. & Cheng, C. W., 2014, In : Disease Markers. 2014, 617150.

Research output: Contribution to journalArticle

MicroRNAs
Cell Movement
Colorectal Neoplasms
Cells
Tissue
58 Citations (Scopus)

MicroRNA-296-5p (miR-296-5p) functions as a tumor suppressor in prostate cancer by directly targeting Pin1

Lee, K. H., Lin, F. C., Hsu, T. I., Lin, J. T., Guo, J. H., Tsai, C. H., Lee, Y. C., Lee, Y. C., Chen, C. L., Hsiao, M. & Lu, P. J., 2014, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1843, 9, p. 2055-2066 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Prostatic Neoplasms
Neoplasms
3' Untranslated Regions
Cell Line
11 Citations (Scopus)

MicroRNA expression profiling in PBMCs: A potential diagnostic biomarker of chronic hepatitis C

Chang, C. C., Lin, C. C., Hsieh, W. L., Lai, H. W., Tsai, C. H. & Cheng, Y. W., 2014, In : Disease Markers. 2014, 367157.

Research output: Contribution to journalArticle

Biomarkers
Chronic Hepatitis C
MicroRNAs
Regression analysis
Logistics
99 Citations (Scopus)

MiR-30 as a tumor suppressor connects EGF/Src signal to ERG and EMT

Kao, C. J., Martiniez, A., Shi, X. B., Yang, J., Evans, C. P., Dobi, A., Devere White, R. W. & Kung, H. J., May 8 2014, In : Oncogene. 33, 19, p. 2495-2503 9 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Epidermal Growth Factor
Genes
Neoplasms
Prostatic Neoplasms
22 Citations (Scopus)

MiR326 maturation is crucial for VEGF-C-driven cortactin expression and esophageal cancer progression

Hong, C. C., Chen, P. S., Chiou, J., Chiu, C. F., Yang, C. Y., Hsiao, M., Chang, Y. W., Yu, Y. H., Hung, M. C., Hsu, N. W., Shiah, S. G., Hsu, N. Y. & Su, J. L., Nov 1 2014, In : Cancer Research. 74, 21, p. 6280-6290 11 p.

Research output: Contribution to journalArticle

Cortactin
Vascular Endothelial Growth Factor C
Esophageal Neoplasms
Actin Cytoskeleton
Neoplasms
19 Citations (Scopus)

MiRNA-221 negatively regulated downstream p27Kip1 gene expression involvement in pterygium pathogenesis

Wu, C. W., Cheng, Y. W., Hsu, N. Y., Yeh, K. T., Tsai, Y. Y., Chiang, C. C., Wang, W. R. & Tung, J. N., Jul 18 2014, In : Molecular Vision. 20, p. 1048-1056 9 p.

Research output: Contribution to journalArticle

Pterygium
Catenins
Gene Expression
MicroRNAs
Small Untranslated RNA
16 Citations (Scopus)

Modified salicylanilide and 3-phenyl-2 H -benzo[ e ][1,3]oxazine-2,4(3 H)-dione derivatives as novel inhibitors of osteoclast differentiation and bone resorption

Chen, C. L., Liu, F. L., Lee, C. C., Chen, T. C., Ahmed Ali, A. A., Sytwu, H. K., Chang, D. M. & Huang, H. S., Oct 9 2014, In : Journal of Medicinal Chemistry. 57, 19, p. 8072-8085 14 p.

Research output: Contribution to journalArticle

Salicylanilides
Osteoclasts
Bone Resorption
Osteogenesis
Bone Density Conservation Agents
36 Citations (Scopus)

Modulation of angiogenesis by thyroid hormone and hormone analogues: Implications for cancer management

Mousa, S. A., Lin, H. Y., Tang, H. Y., Hercbergs, A., Luidens, M. K. & Davis, P. J., 2014, In : Angiogenesis. 17, 3, p. 463-469 7 p.

Research output: Contribution to journalArticle

Thyroid Hormones
Modulation
Hormones
Thyroid Hormone Receptors
Neoplasms
8 Citations (Scopus)

Moniliformediquinone induces in vitro and in vivo antitumor activity through glutathione involved DNA damage response and mitochondrial stress in human hormone refractory prostate cancer

Hsu, J. L., Lee, Y. J., Leu, W. J., Dong, Y. S., Pan, S. L., Uang, B. J. & Guh, J. H., 2014, In : Journal of Urology. 191, 5, p. 1429-1438 10 p.

Research output: Contribution to journalArticle

DNA Damage
Glutathione
Prostatic Neoplasms
Hormones
Mitochondrial Membrane Potential
27 Citations (Scopus)

Mutants TP53 p.R273H and p.R273C but not p.R273G Enhance Cancer Cell Malignancy

Li, J., Yang, L., Gaur, S., Zhang, K., Wu, X., Yuan, Y. C., Li, H., Hu, S., Weng, Y. & Yen, Y., Jan 1 2014, In : Human Mutation. 35, 5, p. 575-584 10 p.

Research output: Contribution to journalArticle

Mutation
Neoplasms
BRCA1 Protein
p53 Genes
Molecular Dynamics Simulation
15 Citations (Scopus)

Nickel accumulation in lung tissues is associated with increased risk of p53 mutation in lung cancer patients

Chiou, Y. H., Wong, R. H., Chao, M. R., Chen, C. Y., Liou, S. H. & Lee, H., Oct 1 2014, In : Environmental and Molecular Mutagenesis. 55, 8, p. 624-632 9 p.

Research output: Contribution to journalArticle

Nickel
Lung Neoplasms
Lung
Mutation
DNA Repair
9 Citations (Scopus)

NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells

Wu, S. Y., Pan, S. L., Xiao, Z. Y., Hsu, J. L., Chen, M. C., Lee, K. H. & Teng, C. M., Nov 5 2014, In : PLoS One. 9, 11, e112220.

Research output: Contribution to journalArticle

DNA topoisomerase (ATP-hydrolysing)
Type II DNA Topoisomerase
Poisons
Renal Cell Carcinoma
DNA damage
14 Citations (Scopus)

Orally active microtubule-targeting agent, MPT0B271, for the treatment of human non-small cell lung cancer, alone and in combination with erlotinib

Tsai, A. C., Wang, C. Y., Liou, J. P., Pai, H. C., Hsiao, C. J., Chang, J. Y., Wang, J. C., Teng, C. M. & Pan, S. L., 2014, In : Cell Death and Disease. 5, 4, e1162.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Microtubules
Tubulin
Cyclin B1
Therapeutics
35 Citations (Scopus)

Paxillin promotes tumor progression and predicts survival and relapse in oral cavity squamous cell carcinoma by microRNA-218 targeting

Wu, D. W., Chuang, C. Y., Lin, W. L., Sung, W. W., Cheng, Y. W. & Lee, H., 2014, In : Carcinogenesis. 35, 8

Research output: Contribution to journalArticle

Paxillin
MicroRNAs
Mouth
Squamous Cell Carcinoma
Recurrence
11 Citations (Scopus)

Pharmacologic down-regulation of EZH2 suppresses bladder cancer in vitro and in vivo

Tang, S. H., Huang, H. S., Wu, H. U., Tsai, Y. T., Chuang, M. J., Yu, C. P., Huang, S. M., Sun, G. H., Chang, S. Y., Hsiao, P. W., Yu, D. S. & Cha, T. L., 2014, In : Oncotarget. 5, 21, p. 10342-10355 14 p.

Research output: Contribution to journalArticle

Urinary Bladder Neoplasms
Down-Regulation
Neoplasms
Growth
Emodin
40 Citations (Scopus)

Phosphorylation of paxillin confers cisplatin resistance in non-small cell lung cancer via activating ERK-mediated Bcl-2 expression

Wu, D. W., Wu, T. C., Wu, J. Y., Cheng, Y. W., Chen, Y. C., Lee, M. C., Chen, C. Y. & Lee, H., Aug 28 2014, In : Oncogene. 33, 35, p. 4385-4395 11 p.

Research output: Contribution to journalArticle

Paxillin
Non-Small Cell Lung Carcinoma
Cisplatin
Phosphorylation
Neoplasms
41 Citations (Scopus)

Radiation induces senescence and a bystander effect through metabolic alterations.

Liao, E. C., Hsu, Y. T., Chuah, Q. Y., Lee, Y. J., Hu, J. Y., Huang, T. C., Yang, P. M. & Chiu, S. J., 2014, In : Cell Death and Disease. 5

Research output: Contribution to journalArticle

Bystander Effect
Radiation
Glycolysis
Lactic Acid
Anaphase
22 Citations (Scopus)

Reciprocal regulation of autophagy and dNTP pools in human cancer cells

Chen, W., Zhang, L., Zhang, K., Zhou, B., Kuo, M. L., Hu, S., Chen, L., Tang, M., Chen, Y. R., Yang, L., Ann, D. K. & Yen, Y., Jan 1 2014, In : Autophagy. 10, 7, p. 1272-1284 13 p.

Research output: Contribution to journalArticle

Deoxyribonucleosides
Autophagy
Ribonucleotide Reductases
Neoplasms
Sirolimus
13 Citations (Scopus)

Ring fusion strategy for the synthesis of anthra[2,3-d ]oxazole-2-thione-5,10-dione homologues as DNA topoisomerase inhibitors and as antitumor agents

Chen, C. L., Liu, F. L., Lee, C. C., Chen, T. C., Chang, W. W., Guh, J. H., Ahmed Ali, A. A., Chang, D. M. & Huang, H. S., Nov 24 2014, In : European Journal of Medicinal Chemistry. 87, p. 30-38 9 p.

Research output: Contribution to journalArticle

Topoisomerase Inhibitors
Oxazoles
Thiones
Type I DNA Topoisomerase
Antineoplastic Agents
15 Citations (Scopus)

SCP phosphatases suppress renal cell carcinoma by stabilizing PML and inhibiting mTOR/HIF signaling

Lin, Y. C., Lu, L. T., Chen, H. Y., Duan, X., Lin, X., Feng, X. H., Tang, M. J. & Chen, R. H., Dec 1 2014, In : Cancer Research. 74, 23, p. 6935-6946 12 p.

Research output: Contribution to journalArticle

Renal Cell Carcinoma
Phosphoric Monoester Hydrolases
Leukemia
Neoplasms
Down-Regulation
56 Citations (Scopus)

Sirtuin 7 plays a role in ribosome biogenesis and protein synthesis

Tsai, Y. C., Greco, T. M. & Cristea, I. M., 2014, In : Molecular and Cellular Proteomics. 13, 1, p. 73-83 11 p.

Research output: Contribution to journalArticle

Transcription
Ribosomes
Transfer RNA
Ribosomal DNA
Purification
13 Citations (Scopus)

Suppression of pancreatic cancer by sulfated non-anticoagulant low molecular weight heparin

Sudha, T., Yalcin, M., Lin, H. Y., Elmetwally, A. M., Nazeer, T., Arumugam, T., Phillips, P. & Mousa, S. A., Aug 1 2014, In : Cancer Letters. 350, 1-2, p. 25-33 9 p.

Research output: Contribution to journalArticle

Low Molecular Weight Heparin
Pancreatic Neoplasms
Heparin
gemcitabine
Neoplasms
32 Citations (Scopus)

Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in liver cancer cells in vitro and in vivo

Chen, C. H., Chen, M. C., Wang, J. C., Tsai, A. C., Chen, C. S., Liou, J. P., Pan, S. L. & Teng, C. M., 2014, In : Clinical Cancer Research. 20, 5, p. 1274-1287 14 p.

Research output: Contribution to journalArticle

Histone Deacetylase Inhibitors
Liver Neoplasms
Heterografts
Cell Survival
Histone Code
26 Citations (Scopus)

The mechanisms by which pardaxin, a natural cationic antimicrobial peptide, targets the endoplasmic reticulum and induces c-FOS

Ting, C. H., Huang, H. N., Huang, T. C., Wu, C. J. & Chen, J. Y., Apr 2014, In : Biomaterials. 35, 11, p. 3627-3640 14 p.

Research output: Contribution to journalArticle

Antimicrobial Cationic Peptides
Cell death
Endoplasmic Reticulum
Peptides
Transcription factors
9 Citations (Scopus)

The prognostic value of ribonucleotide reductase small subunit M2 in predicting recurrence for prostate cancers

Huang, Y., Liu, X., Wang, Y. H., Yeh, S. D., Chen, C. L., Nelson, R. A., Chu, P., Wilson, T. & Yen, Y., Jan 2014, In : Urologic Oncology: Seminars and Original Investigations. 32, 1

Research output: Contribution to journalArticle

Prostatic Neoplasms
Recurrence
Capsules
Neoplasm Grading
Metalloproteases
18 Citations (Scopus)

Thyroid hormone inhibition in L6 myoblasts of IGF-I-mediated glucose uptake and proliferation: New roles for integrin αvβ3

Incerpi, S., Hsieh, M. T., Lin, H. Y., Cheng, G. Y., De Vito, P., Fiore, A. M., Ahmed, R. G., Salvia, R., Candelotti, E., Leone, S., Luly, P., Pedersen, J. Z., Davis, F. B. & Davis, P. J., Jul 15 2014, In : American Journal of Physiology - Cell Physiology. 307, 2

Research output: Contribution to journalArticle

Myoblasts
Insulin-Like Growth Factor I
Thyroid Hormones
Integrins
Glucose
23 Citations (Scopus)

Tumor suppressor FOXO3 regulates ribonucleotide reductase subunit RRM2B and impacts on survival of cancer patients

Cho, E. C., Kuo, M. L., Liu, X., Yang, L., Hsieh, Y. C., Wang, J., Cheng, Y. & Yen, Y., 2014, In : Oncotarget. 5, 13, p. 4834-4844 11 p.

Research output: Contribution to journalArticle

Ribonucleotide Reductases
Survival
Neoplasms
DNA Replication
Tumor Biomarkers
25 Citations (Scopus)

Up-Regulation of FOXM1 by E6 Oncoprotein through the MZF1/NKX2-1 Axis Is Required for Human Papillomavirus-Associated Tumorigenesis

Chen, P. M., Cheng, Y. W., Wang, Y. C., Wu, T. C., Chen, C. Y. & Lee, H., 2014, In : Neoplasia. 16, 11, p. 961-971 11 p.

Research output: Contribution to journalArticle

Human papillomavirus 18
Human papillomavirus 16
Oncogene Proteins
Carcinogenesis
Up-Regulation
19 Citations (Scopus)

Vascular endothelial growth factor gene polymorphism and protein expression in the pathogenesis of pterygium

Peng, M. L., Tsai, Y. Y., Tung, J. N., Chiang, C. C., Huang, Y. C., Lee, H. & Cheng, Y. W., 2014, In : British Journal of Ophthalmology. 98, 4, p. 556-561 6 p.

Research output: Contribution to journalArticle

Pterygium
Vascular Endothelial Growth Factor A
Genotype
Proteins
Control Groups
2013
31 Citations (Scopus)

Activated PAR-2 regulates pancreatic cancer progression through ILK/HIF-α-induced TGF-α expression and MEK/VEGF-a-mediated angiogenesis

Chang, L. H., Pan, S. L., Lai, C. Y., Tsai, A. C. & Teng, C. M., Aug 2013, In : American Journal of Pathology. 183, 2, p. 566-575 10 p.

Research output: Contribution to journalArticle

PAR-2 Receptor
Mitogen-Activated Protein Kinase Kinases
Transforming Growth Factors
Pancreatic Neoplasms
Vascular Endothelial Growth Factor A
16 Citations (Scopus)

Activation of a novel ubiquitin-independent proteasome pathway when RNA polymerase II encounters a protein roadblock

Ban, Y., Ho, C. W., Lin, R. K., Lyu, Y. L. & Liu, L-F., 2013, In : Molecular and Cellular Biology. 33, 20, p. 4008-4016 9 p.

Research output: Contribution to journalArticle

RNA Polymerase II
Proteasome Endopeptidase Complex
Ubiquitin
Adenosine Triphosphatases
Type II DNA Topoisomerase
23 Citations (Scopus)

Activation of NF-κB by SOD2 promotes the aggressiveness of lung adenocarcinoma by modulating NKX2-1-mediated IKKβ expression

Chen, P. M., Wu, T. C., Wang, Y. C., Cheng, Y. W., Sheu, G. T., Chen, C. Y. & Lee, H., Nov 2013, In : Carcinogenesis. 34, 11, p. 2655-2663 9 p.

Research output: Contribution to journalArticle

Messenger RNA
Neoplasms
Lung
Epithelial-Mesenchymal Transition
Survival
49 Citations (Scopus)

Amplification of FRS2 and activation of FGFR/FRS2 signaling pathway in high-grade liposarcoma

Zhang, K., Chu, K., Wu, X., Gao, H., Wang, J., Yuan, Y. C., Loera, S., Ho, K., Wang, Y., Chow, W., Un, F., Chu, P. & Yen, Y., Jan 15 2013, In : Cancer Research. 73, 4, p. 1298-1307 10 p.

Research output: Contribution to journalArticle

Fibroblast Growth Factor Receptors
Liposarcoma
Sarcoma
Proteins
Receptor, Fibroblast Growth Factor, Type 2
12 Citations (Scopus)

Association of epidermal growth factor receptor mutations with human papillomavirus 16/18 E6 oncoprotein expression in non-small cell lung cancer

Tung, M. C., Wu, H. H., Cheng, Y. W., Wang, L., Chen, C. Y., Yeh, S. D., Wu, T. C. & Lee, H., Sep 15 2013, In : Cancer. 119, 18, p. 3367-3376 10 p.

Research output: Contribution to journalArticle

Human papillomavirus 18
Human papillomavirus 16
Oncogene Proteins
Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
4 Citations (Scopus)

BPDE-like DNA adduct level in oral tissue may act as a risk biomarker of oral cancer

Chuang, C. Y., Tung, J. N., Su, M. C., Wu, B. C., Hsin, C. H., Chen, Y. J., Yeh, K. T., Lee, H. & Cheng, Y. W., Jan 2013, In : Archives of Oral Biology. 58, 1, p. 102-109 8 p.

Research output: Contribution to journalArticle

DNA Adducts
Mouth Neoplasms
Biomarkers
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide
Smoke
11 Citations (Scopus)

Carboxyl-terminal modulator protein positively regulates Akt phosphorylation and acts as an oncogenic driver in breast cancer

Liu, Y. P., Liao, W. C., Ger, L. P., Chen, J. C., Hsu, T. I., Lee, Y. C., Chang, H. T., Chen, Y. C., Jan, Y. H., Lee, K. H., Zeng, Y. H., Hsiao, M. & Lu, P. J., Oct 15 2013, In : Cancer Research. 73, 20, p. 6194-6205 12 p.

Research output: Contribution to journalArticle

Phosphorylation
Breast Neoplasms
Proteins
Estrogens
1-Phosphatidylinositol 4-Kinase
16 Citations (Scopus)

Chromosomal Instability Triggered by Rrm2b Loss Leads to IL-6 Secretion and Plasmacytic Neoplasms

Chang, L., Guo, R., Huang, Q. & Yen, Y., May 30 2013, In : Cell Reports. 3, 5, p. 1389-1397 9 p.

Research output: Contribution to journalArticle

Chromosomal Instability
Interleukin-6
DNA Damage
Plasma Cell Neoplasms
Deoxyribonucleotides
7 Citations (Scopus)

Depletion of 4E-BP1 and regulation of autophagy lead to YXM110-induced anticancer effects

Lai, C. Y., Pan, S. L., Yang, X. M., Chang, L. H., Chang, Y. L., Yang, P. C., Lee, K. H. & Teng, C. M., Sep 2013, In : Carcinogenesis. 34, 9, p. 2050-2060 11 p.

Research output: Contribution to journalArticle

Autophagy
Cell Death
Light
JNK Mitogen-Activated Protein Kinases
Vacuoles
6 Citations (Scopus)

Different impact of IL10 haplotype on prognosis in lung squamous cell carcinoma and adenocarcinoma

Wang, Y. C., Sung, W. W., Wang, L., Cheng, Y. W., Chen, C. Y., Wu, T. C., Shieh, S. H. & Lee, H., Jun 2013, In : Anticancer Research. 33, 6, p. 2729-2736 8 p.

Research output: Contribution to journalArticle

Interleukin-10
Haplotypes
Squamous Cell Carcinoma
Adenocarcinoma
Lung
31 Citations (Scopus)

Furanylazaindoles: Potent anticancer agents in vitro and in vivo

Lee, H. Y., Pan, S. L., Su, M-C., Liu, Y-M., Kuo, C-C., Chang, Y-T., Wu, J-S., Nien, C-Y., Mehndiratta, S., Chang, C-Y., Wu, S-Y., Lai, M-J., Chang, J-Y. & Liou, J. P., 2013, In : Journal of Medicinal Chemistry. 56, 20, p. 8008-8018 11 p.

Research output: Contribution to journalArticle

Tubulin
Antineoplastic Agents
Body Weight Changes
G2 Phase
Colchicine