Ph.D. Program for Cancer Molecular Biology and Drug Discovery

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output 1996 2020

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Article
2016
34 Citations (Scopus)

Elevated HMGA2 expression is associated with cancer aggressiveness and predicts poor outcome in breast cancer

Wu, J., Zhang, S., Shan, J., Hu, Z., Liu, X., Chen, L., Ren, X., Yao, L., Sheng, H., Li, L., Ann, D., Yen, Y., Wang, J. & Wang, X., Jul 1 2016, In : Cancer Letters. 376, 2, p. 284-292 9 p.

Research output: Contribution to journalArticle

AT-Hook Motifs
Breast Neoplasms
Neoplasms
Biological Phenomena
Transcriptome
2 Citations (Scopus)

Environmental exposure and HPV infection may act synergistically to induce lung tumorigenesis in nonsmokers

Cheng, Y. W., Lin, F. C. F., Chen, C. Y. & Hsu, N. Y., Apr 12 2016, In : Oncotarget. 7, 15, p. 19850-19862 13 p.

Research output: Contribution to journalArticle

Papillomavirus Infections
Environmental Exposure
Carcinogenesis
Lung
Benzo(a)pyrene
17 Citations (Scopus)

Erlotinib-Conjugated Iron Oxide Nanoparticles as a Smart Cancer-Targeted Theranostic Probe for MRI

Ali, A. A. A., Hsu, F. T., Hsieh, C. L., Shiau, C. Y., Chiang, C. H., Wei, Z. H., Chen, C. Y. & Huang, H. S., Nov 11 2016, In : Scientific Reports. 6, 36650.

Research output: Contribution to journalArticle

Nanoparticles
Neoplasms
Transmission Electron Microscopy
Heterografts
Nude Mice
1 Citation (Scopus)

Evaluation of the In Vivo Therapeutic Effects of Radix Paeoniae Rubra Ethanol Extract with the Hypoglycemic Activities Measured from Multiple Cell-Based Assays

Chang, C. C., Yuan, W., Lin, Y. L., Liu, R. S., Juan, Y. C., Sun, W. H., Tsay, H. J., Huang, H. C., Lee, Y. C. & Liu, H. K., Jan 1 2016, In : Evidence-based Complementary and Alternative Medicine. 2016, 3262790.

Research output: Contribution to journalArticle

Paeonia
Therapeutic Uses
Hypoglycemic Agents
Ethanol
Polyphenols
5 Citations (Scopus)

Expression levels of estrogen receptor α mRNA in peripheral blood cells are an independent biomarker for postmenopausal osteoporosis

Chou, C. W., Chiang, T. I., Chang, I. C., Huang, C. H. & Cheng, Y. W., Jun 1 2016, In : BBA Clinical. 5, p. 124-129 6 p.

Research output: Contribution to journalArticle

Postmenopausal Osteoporosis
Estrogen Receptors
Blood Cells
Biomarkers
Messenger RNA
13 Citations (Scopus)

Expression Pattern and Clinicopathological Relevance of the Indoleamine 2,3-Dioxygenase 1/Tryptophan 2,3-Dioxygenase Protein in Colorectal Cancer

Chen, I. C., Lee, K. H., Hsu, Y. H., Wang, W. R., Chen, C. M. & Cheng, Y. W., 2016, In : Disease Markers. 2016, 8169724.

Research output: Contribution to journalArticle

Tryptophan Oxygenase
Indoleamine-Pyrrole 2,3,-Dioxygenase
Colorectal Neoplasms
beta Catenin
Proteins
15 Citations (Scopus)
Unfolded Protein Response
Autophagy
Colorectal Neoplasms
Up-Regulation
Endoplasmic Reticulum Stress
2 Citations (Scopus)

Glucocorticoids may compromise the effect of gefitinib in non-small cell lung cancer

Wang, H. Y., Chang, Y. L., Cheng, C. C., Chao, M. W., Lin, S. I., Pan, S-L., Hsu, C. C., Liu, T. W., Cheng, H. C., Tseng, C. P., Liu, S. J., Tsai, H. J., Chang, H. Y. & Hsu, J. T. A., 2016, In : Oncotarget. 7, 52, p. 85917-85928 12 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Glucocorticoids
Protein-Tyrosine Kinases
Epidermal Growth Factor Receptor
Heterografts
12 Citations (Scopus)

Glucose-regulated protein 94 mediates cancer progression via AKT and eNOS in hepatocellular carcinoma

Huang, C. Y., Batzorig, U., Cheng, W. L., Huang, M. T., Chen, W. Y., Wei, P. L. & Chang, Y. J., Apr 1 2016, In : Tumor Biology. 37, 4, p. 4295-4304

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Neoplasms
glucose-regulated proteins
AMP-Activated Protein Kinases
Heterografts
6 Citations (Scopus)
AT-Hook Motifs
HSP90 Heat-Shock Proteins
Epithelial-Mesenchymal Transition
Hooks
colorectal neoplasms
6 Citations (Scopus)

HIF-1-alpha links mitochondrial perturbation to the dynamic acquisition of breast cancer tumorigenicity

Kuo, C. Y., Cheng, C. T., Hou, P., Lin, Y. P., Ma, H., Chung, Y., Chi, K., Chen, Y., Li, W., Kung, H. J. & Ann, D. K., Jun 7 2016, In : Oncotarget. 7, 23, p. 34052-34069 18 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Breast Neoplasms
Fumarates
Succinic Acid
Hypoxia-Inducible Factor-Proline Dioxygenases

Identification of a new class of WNT1 inhibitor: Cancer cells migration, G-quadruplex stabilization and target validation

Chang, L. C., Chen, T. C., Chen, S. J., Chen, C. L., Lee, C. C., Wu, S. H., Yen, Y., Huang, H. S. & Lin, J. J., Oct 18 2016, In : Oncotarget. 7, 42, p. 67986-68001 16 p.

Research output: Contribution to journalArticle

G-Quadruplexes
Cell Movement
Neoplasms
Wnt Signaling Pathway
Excipients
2 Citations (Scopus)

Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES)

Huang, K. W., Hsu, K. C., Chu, L. Y., Yang, J. M., Yuan, H. S. & Hsiao, Y. Y., Sep 8 2016, In : Journal of Medicinal Chemistry. 59, 17, p. 8019-8029 11 p.

Research output: Contribution to journalArticle

Exonucleases
Lassa Fever
Lassa virus
Viral Proteins
Virus Replication
3 Citations (Scopus)

Indole-3-ethylsulfamoylphenylacrylamides with potent anti-proliferative and anti-angiogenic activities

Mehndiratta, S., Pan, S. L., Kumar, S. & Liou, J. P., Jul 1 2016, In : Anti-Cancer Agents in Medicinal Chemistry. 16, 7, p. 907-913 7 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Acrylamide
Acrylamides
Neoplasms
Nude Mice
9 Citations (Scopus)
Metallothionein
Computer Simulation
Hepatocellular Carcinoma
Genes
Therapeutics
10 Citations (Scopus)

Integrin β3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma

Yang, S. H., Lin, H. Y., Changou, C. A., Chen, C. H., Liu, Y. R., Wang, J., Jiang, X., Luh, F. & Yen, Y., Jan 1 2016, In : Oncotarget. 7, 1, p. 362-373 12 p.

Research output: Contribution to journalArticle

Lovastatin
Cholangiocarcinoma
Integrins
Cell Adhesion
Intercellular Adhesion Molecule-1
29 Citations (Scopus)

Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice

Wu, C-H., Chen, H. Y., Wang, C-W., Shieh, T. M., Huang, T-C., Lin, L. C., Wang, K. L. & Hsia, S-M., 2016, In : Oncotarget. 7, 45, p. 73432-73447 16 p.

Research output: Contribution to journalArticle

Autophagy
Endometrial Neoplasms
Apoptosis
Growth
Neoplasms

KLF4 functions as an activator of the androgen receptor through reciprocal feedback

Siu, M-K., Suau, F., Chen, W-Y., Tsai, Y-C., Tsai, H-Y., Yeh, H-L. & Liu, Y-N., Dec 2016, In : Oncogenesis. 5, 12, p. e282

Research output: Contribution to journalArticle

Activator Appliances
Androgen Receptors
MicroRNAs
Prostatic Neoplasms
Neoplasm Metastasis
5 Citations (Scopus)

LTP-1, a novel antimitotic agent and Stat3 inhibitor, inhibits human pancreatic carcinomas in vitro and in vivo

Huang, H. L., Chao, M. W., Chen, C. C., Cheng, C. C., Chen, M. C., Lin, C. F., Liou, J. P., Teng, C. M. & Pan, S. L., Jun 9 2016, In : Scientific Reports. 6, 27794.

Research output: Contribution to journalArticle

Antimitotic Agents
Pancreatic Neoplasms
Polyploidy
Microtubules
Growth
5 Citations (Scopus)

Methyl Protodioscin, a Steroidal Saponin, Inhibits Neointima Formation in Vitro and in Vivo

Chung, Y. L., Pan, C. H., Wang, C. C. N., Hsu, K. C., Sheu, M. J., Chen, H. F. & Wu, C. H., Jun 24 2016, In : Journal of Natural Products. 79, 6, p. 1635-1644 10 p.

Research output: Contribution to journalArticle

Neointima
Saponins
Vascular Smooth Muscle
Smooth Muscle Myocytes
Muscle
1 Citation (Scopus)

MiR-30c-2* negative regulated MTA-1 expression involved in metastasis and drug resistance of HPV-infected non-small cell lung cancer

Wu, Y. L., Hsu, N-Y., Lin, F. C. F., Lee, H. & Cheng, Y-W., Dec 1 2016, In : Surgery (United States). 160, 6, p. 1591-1598 8 p.

Research output: Contribution to journalArticle

Pemetrexed
Drug Resistance
Non-Small Cell Lung Carcinoma
Neoplasm Metastasis
Neoplasms
5 Citations (Scopus)
Antineoplastic Agents
Ovarian Neoplasms
Cisplatin
Apoptosis
Pharmaceutical Preparations
9 Citations (Scopus)

Novel anthra[1,2-c][1,2,5]thiadiazole-6,11-diones as promising anticancer lead compounds: Biological evaluation, characterization & molecular targets determination

Ali, A. A. A., Lee, Y. R., Chen, T. C., Chen, C. L., Lee, C. C., Shiau, C. Y., Chiang, C. H. & Huang, H. S., Apr 1 2016, In : PLoS One. 11, 4, e0154278.

Research output: Contribution to journalArticle

biochemical compounds
Lead compounds
Cells
bioavailability
rifamycins
7 Citations (Scopus)

Novel leptin OB3 peptide-induced signaling and progression in thyroid cancers: Comparison with leptin

Yang, Y. C. S. H., Chin, Y. T., Hsieh, M. T., Lai, H. Y., Ke, C. C., Crawford, D. R., Lee, O. K., Fu, E., Mousa, S. A., Grasso, P., Liu, L-F., Chang, H-Y., Tang, H. Y., Lin, H-Y. & Davis, P. J., May 10 2016, In : Oncotarget. 7, 19, p. 27641-27654 14 p.

Research output: Contribution to journalArticle

leptin (116-130)
Leptin
Thyroid Neoplasms
Adipose Tissue
Cell Proliferation
8 Citations (Scopus)

Novel regulators and molecular mechanisms of p53R2 and its disease relevance

Cho, E. C. & Yen, Y., Apr 1 2016, In : Biochimie. 123, p. 81-84 4 p.

Research output: Contribution to journalArticle

Mitochondria
Ribonucleotide Reductases
Neoplasms
Oncology
Animals
10 Citations (Scopus)

Observation of polarization and thickness dependent third-harmonic generation in multilayer black phosphorus

Wu, H. Y., Yen, Y. & Liu, C. H., Dec 26 2016, In : Applied Physics Letters. 109, 26, 261902.

Research output: Contribution to journalArticle

phosphorus
harmonic generations
flakes
polarization
constrictions
13 Citations (Scopus)

One-pot green hydrothermal synthesis of fluorescent nitrogen-doped carbon nanodots for in vivo bioimaging

Kuo, T. R., Sung, S. Y., Hsu, C. W., Chang, C. J., Chiu, T. C. & Hu, C. C., Jan 1 2016, In : Analytical and Bioanalytical Chemistry. 408, 1, p. 77-82 6 p.

Research output: Contribution to journalArticle

Hydrothermal synthesis
Nitrogen
Carbon
Fluorescence
Optical Imaging
12 Citations (Scopus)

PAK1 confers chemoresistance and poor outcome in non-small cell lung cancer via β-catenin-mediated stemness

Chen, M. J., Wu, D. W., Wang, Y. C., Chen, C. Y. & Lee, H., Oct 7 2016, In : Scientific Reports. 6, 34933.

Research output: Contribution to journalArticle

Catenins
Non-Small Cell Lung Carcinoma
Cisplatin
Drug Therapy
Neoplasms
21 Citations (Scopus)
Phosphatidylinositol 3-Kinases
Protein-Tyrosine Kinases
Cadherins
Mutation
Neoplasms
20 Citations (Scopus)

Paxillin confers resistance to tyrosine kinase inhibitors in EGFR-mutant lung cancers via modulating BIM and Mcl-1 protein stability

Wu, D. W., Chen, C. Y., Chu, C. L. & Lee, H., Feb 4 2016, In : Oncogene. 35, 5, p. 621-630 10 p.

Research output: Contribution to journalArticle

Paxillin
Protein Stability
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Lung Neoplasms
33 Citations (Scopus)

Phenyl Benzenesulfonylhydrazides Exhibit Selective Indoleamine 2,3-Dioxygenase Inhibition with Potent in Vivo Pharmacodynamic Activity and Antitumor Efficacy

Lin, S. Y., Yeh, T. K., Kuo, C. C., Song, J. S., Cheng, M. F., Liao, F. Y., Chao, M. W., Huang, H. L., Chen, Y. L., Yang, C. Y., Wu, M. H., Hsieh, C. L., Hsiao, W., Peng, Y. H., Wu, J. S., Lin, L. M., Sun, M., Chao, Y. S., Shih, C., Wu, S. Y. & 3 others, Pan, S. L., Hung, M. S. & Ueng, S. H., Jan 14 2016, In : Journal of Medicinal Chemistry. 59, 1, p. 419-430 12 p.

Research output: Contribution to journalArticle

Indoleamine-Pyrrole 2,3,-Dioxygenase
Tryptophan
Kynurenine
Immune Tolerance
Immunotherapy
2 Citations (Scopus)

Polygonum multiflorum Decreases Airway Allergic Symptoms in a Murine Model of Asthma

Lee, C. C., Lee, Y. L., Wang, C. N., Tsai, H. C., Chiu, C. L., Liu, L. F., Lin, H. Y. & Wu, R., Feb 1 2016, In : American Journal of Chinese Medicine. 44, 1, p. 133-147 15 p.

Research output: Contribution to journalArticle

Asthma
Ovalbumin
Cytokines
Respiratory Hypersensitivity
Transcription Factor 3
5 Citations (Scopus)

Precision Medicine and Pancreatic Cancer

Farrell, J. J., Moughan, J., Wong, J. L., Regine, W. F., Schaefer, P., Benson, A. B., Macdonald, J. S., Liu, X., Yen, Y., Lai, R., Zheng, Z., Bepler, G., Guha, C. & Elsaleh, H., Nov 1 2016, In : Pancreas. 45, 10, p. 1485-1493 9 p.

Research output: Contribution to journalArticle

gemcitabine
Precision Medicine
Pancreatic Neoplasms
Deoxycytidine Kinase
Radiation Oncology
18 Citations (Scopus)
Camptothecin
Glioblastoma
Nanoparticles
Apoptosis
Glioma
5 Citations (Scopus)

Primary versus castration-resistant prostate cancer: Modeling through novel murine prostate cancer cell line

Daoud, G., Monzer, A., Bahmad, H., Chamaa, F., Hamdar, L., Mouhieddine, T. H., Shayya, S., Eid, A., Kobeissy, F., Liu, Y. N. & Abou-Kheir, W., May 17 2016, In : Oncotarget. 7, 20, p. 28961-28975 15 p.

Research output: Contribution to journalArticle

Castration
Androgens
Prostatic Neoplasms
Cell Line
Neoplasm Invasiveness
11 Citations (Scopus)

Prognostic and therapeutic value of mitochondrial serine hydroxyl-methyltransferase 2 as a breast cancer biomarker

Zhang, L., Chen, Z., Xue, D., Zhang, Q., Liu, X., Luh, F., Hong, L., Zhang, H., Pan, F., Liu, Y., Chu, P., Zheng, S., Lou, G. & Yen, Y., Nov 1 2016, In : Oncology Reports. 36, 5, p. 2489-2500 12 p.

Research output: Contribution to journalArticle

Tumor Biomarkers
Hydroxyl Radical
Serine
Breast Neoplasms
Therapeutics
14 Citations (Scopus)

Proton pump inhibitors and risk of periampullary cancers - A nested case-control study

Chien, L-N., Huang, Y. J., Shao, Y-H., Chang, C. J., Chuang, M. T., Chiou, H-Y. & Yen, Y., Mar 15 2016, In : International Journal of Cancer. 138, 6, p. 1401-1409 9 p.

Research output: Contribution to journalArticle

Proton Pump Inhibitors
Case-Control Studies
Neoplasms
Taiwan
Helicobacter pylori
4 Citations (Scopus)

Pu-erh Tea Extract Attenuates Nicotine-Induced Foam Cell Formation in Primary Cultured Monocytes: An in Vitro Mechanistic Study

Tu, S. H., Chen, M. Y., Chen, L. C., Mao, Y. T., Ho, C. H., Lee, W. J., Lin, Y-K., Pan, M. H., Lo, C. Y., Chen, C. L., Yen, Y., Whang-Peng, J., Ho, C. T., Wu, C. H. & Ho, Y. S., Apr 27 2016, In : Journal of Agricultural and Food Chemistry. 64, 16, p. 3186-3195 10 p.

Research output: Contribution to journalArticle

foam cells
Foam Cells
nicotine
Tea
Nicotine
24 Citations (Scopus)

PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress

Kuo, M. L., Lee, M. B. E., Tang, M., Den Besten, W., Hu, S., Sweredoski, M. J., Hess, S., Chou, C. M., Changou, C. A., Su, M., Jia, W., Su, L. & Yen, Y., Jan 6 2016, In : Scientific Reports. 6, 18846.

Research output: Contribution to journalArticle

Oxidative Stress
Pyrroline Carboxylate Reductases
Fibroblasts
Ribonucleotide Reductases
Foreskin
20 Citations (Scopus)

Reduction of microRNA-184 by E6 oncoprotein confers cisplatin resistance in lung cancer via increasing Bcl-2

Tung, M. C., Lin, P. L., Cheng, Y. W., Wu, D. W., Yeh, S. D., Chen, C. Y. & Lee, H., May 31 2016, In : Oncotarget. 7, 22, p. 32362-32374 13 p.

Research output: Contribution to journalArticle

Oncogene Proteins
MicroRNAs
Cisplatin
Lung Neoplasms
Drug Therapy
10 Citations (Scopus)
Cyclin-Dependent Kinases
Colorectal Neoplasms
Diphosphates
Deoxyribonucleosides
Ribonucleosides
2 Citations (Scopus)

Research of StemBios cell therapy on dental implants containing nanostructured surfaces: Biomechanical behaviors, microstructural characteristics, and clinical trial

Ou, K. L., Weng, C. C., Wu, C. C., Lin, Y. H., Chiang, H. J., Yang, T. S., Wang, J., Yen, Y., Cheng, H. Y. & Sugiatno, E., Feb 1 2016, In : Implant Dentistry. 25, 1, p. 63-73 11 p.

Research output: Contribution to journalArticle

Dental Implants
Cell- and Tissue-Based Therapy
Osseointegration
Clinical Trials
Research
21 Citations (Scopus)

REST reduction is essential for hypoxia-induced neuroendocrine differentiation of prostate cancer cells by activating autophagy signaling

Lin, T. P., Chang, Y. T., Lee, S. Y., Campbell, M., Wang, T. C., Shen, S. H., Chung, H. J., Chang, Y. H., Chiu, A. W., Pan, C. C., Lin, C. H., Chu, C. Y., Kung, H. J., Cheng, C. Y. & Chang, P. C., May 1 2016, In : Oncotarget. 7, 18, p. 26137-26151 15 p.

Research output: Contribution to journalArticle

Transcriptional Silencer Elements
Autophagy
Prostatic Neoplasms
Transcription Factors
AMP-Activated Protein Kinases
8 Citations (Scopus)

Resveratrol inhibits proliferation of myometrial and leiomyoma cells and decreases extracellular matrix-associated protein expression

Wu, C. H., Shieh, T. M., Wei, L. H., Cheng, T. F., Chen, H. Y., Huang, T. C., Wang, K. L. & Hsia, S. M., May 1 2016, In : Journal of Functional Foods. 23, p. 241-252 12 p.

Research output: Contribution to journalArticle

Extracellular Matrix Proteins
resveratrol
Leiomyoma
extracellular matrix
smooth muscle

RINT-1 interacts with MSP58 within nucleoli and plays a role in ribosomal gene transcription

Yang, C. P., Kuo, Y. L., Lee, Y. C., Lee, K. H., Chiang, C. W., Wang, J. M., Hsu, C. C., Chang, W. C. & Lin, D. Y., Sep 16 2016, In : Biochemical and Biophysical Research Communications. 478, 2, p. 873-880 8 p.

Research output: Contribution to journalArticle

Transcription
Genes
Proteins
Ribosomal DNA
Ribosomes
7 Citations (Scopus)

Selective recognition and stabilization of new ligands targeting the potassium form of the human telomeric G-quadruplex DNA

Lin, Y. H., Chuang, S. M., Wu, P. C., Chen, C. L., Jeyachandran, S., Lo, S. C., Huang, H. S. & Hou, M. H., Aug 11 2016, In : Scientific Reports. 6, 31019.

Research output: Contribution to journalArticle

Potassium
Stabilization
Ligands
DNA
Anthraquinones
19 Citations (Scopus)

Signature miRNAs in colorectal cancers were revealed using a bias reduction small RNA deep sequencing protocol

Sun, G., Cheng, Y. W., Lai, L., Huang, T. C., Wang, J., Wu, X., Wang, Y., Huang, Y., Wang, J., Zhang, K., Hu, S., Yang, J. R. & Yen, Y., 2016, In : Oncotarget. 7, 4, p. 3857-3872 16 p.

Research output: Contribution to journalArticle

RNA Sequence Analysis
High-Throughput Nucleotide Sequencing
MicroRNAs
Colorectal Neoplasms
Rectal Neoplasms
4 Citations (Scopus)

Sterol O-acyltransferase 2 contributes to the yolk cholesterol trafficking during zebrafish embryogenesis

Chang, N. Y., Chan, Y. J., Ding, S. T., Lee, Y. H., Huangfu, W. C. & Liu, I. H., Dec 1 2016, In : PLoS One. 11, 12, e0167644.

Research output: Contribution to journalArticle

cholesterol acyltransferase
Zebrafish
Danio rerio
Embryonic Development
embryogenesis
5 Citations (Scopus)

Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: Identification of functional disparities between azacytidine and decitabine

Hsieh, Y. Y., Huang, T. C., Lo, H. L., Jhan, J. Y., Chen, S. T. & Yang, P. M., May 10 2016, In : Oncotarget. 7, 19, p. 27363-27378 16 p.

Research output: Contribution to journalArticle

decitabine
Azacitidine
Drug Discovery
Genomics
Polypharmacology
12 Citations (Scopus)

TC-N19, a novel dual inhibitor of EGFR and cMET, efficiently overcomes EGFR-TKI resistance in non-small-cell lung cancer cells

Wu, D. W., Chen, T. C., Huang, H. S. & Lee, H., Jun 30 2016, In : Cell death & disease. 7, 6, p. e2290

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Paxillin
Heterografts