Ph.D. Program for Cancer Molecular Biology and Drug Discovery

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output 1996 2020

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2018
5 Citations (Scopus)

Amentoflavone inhibits hepatocellular carcinoma progression through blockage of ERK/NF-κB activation

Lee, K. C., Chen, W. T., Liu, Y. C., Lin, S. S. & Hsu, F. T., Sep 1 2018, In : In Vivo. 32, 5, p. 1097-1103 7 p.

Research output: Contribution to journalArticle

Extracellular Signal-Regulated MAP Kinases
Hepatocellular Carcinoma
Chemical activation
Tumors
Liver
4 Citations (Scopus)
Activating Transcription Factors
CC Chemokines
Epithelial-Mesenchymal Transition
Androgens
Prostatic Neoplasms

A new niclosamide derivatives-B17 can inhibit urological cancers growth through apoptosis-related pathway

Wu, C-L., Chen, C-L., Huang, H-S. & Yu, D-S., Jun 28 2018, In : Cancer Medicine.

Research output: Contribution to journalArticle

Niclosamide
Urologic Neoplasms
Apoptosis
Growth
Control Groups
3 Citations (Scopus)

A novel dual HDAC6 and tubulin inhibitor, MPT0B451, displays anti-tumor ability in human cancer cells in vitro and in vivo

Wu, Y. W., Hsu, K. C., Lee, H. Y., Huang, T. C., Lin, T. E., Chen, Y. L., Sung, T. Y., Liou, J. P., Hwang-Verslues, W. W., Pan, S. L. & HuangFu, W. C., Mar 13 2018, In : Frontiers in Pharmacology. 9, MAR, 205.

Research output: Contribution to journalArticle

Tubulin Modulators
Histone Deacetylases
Neoplasms
Tubulin
Molecular Docking Simulation

A Novel Selective JAK2 Inhibitor Identified Using Pharmacological Interactions

Lin, T. E., HuangFu, W-C., Chao, M-W., Sung, T-Y., Chang, C-D., Chen, Y-Y., Hsieh, J-H., Tu, H-J., Huang, H-L., Pan, S-L. & Hsu, K-C., 2018, In : Frontiers in Pharmacology. 9, p. 1379

Research output: Contribution to journalArticle

Janus Kinases
Phosphotransferases
Binding Sites
Pharmacology
Cytokine Receptors
5 Citations (Scopus)

Anti-TNF-α restricts dengue virus-induced neuropathy

Jhan, M. K., Huangfu, W. C., Chen, Y. F., Kao, J. C., Tsai, T. T., Ho, M. R., Shen, T. J., Tseng, P. C., Wang, Y. T. & Lin, C. F., Jan 1 2018, (Accepted/In press) In : Journal of Leukocyte Biology.

Research output: Contribution to journalArticle

Dengue Virus
Encephalitis
Virus Diseases
Dengue
Neurons
11 Citations (Scopus)

Application of bioconjugation chemistry on biosensor fabrication for detection of TAR-DNA binding protein 43

Dai, Y., Wang, C., Chiu, L. Y., Abbasi, K., Tolbert, B. S., Sauvé, G., Yen, Y. & Liu, C. C., Oct 15 2018, In : Biosensors and Bioelectronics. 117, p. 60-67 8 p.

Research output: Contribution to journalArticle

DNA-Binding Proteins
Biosensing Techniques
Biosensors
DNA
Fabrication
4 Citations (Scopus)

Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction

Cheng, C. T., Qi, Y., Wang, Y. C., Chi, K. K., Chung, Y., Ouyang, C., Chen, Y. R., Oh, M. E., Sheng, X., Tang, Y., Liu, Y. R., Lin, H. H., Kuo, C. Y., Schones, D., Vidal, C. M., Chu, J. C. Y., Wang, H. J., Chen, Y. H., Miller, K. M., Chu, P. & 4 others, Yen, Y., Jiang, L., Kung, H. J. & Ann, D. K., Dec 1 2018, In : Communications Biology. 1, 1, 178.

Research output: Contribution to journalArticle

Open Access
aspartic acid
Starvation
Aspartic Acid
arginine
starvation
3 Citations (Scopus)

Arthroprotective effects of Cf-02 sharing structural similarity with quercetin

Liu, F. C., Lu, J. W., Chien, C. Y., Huang, H. S., Lee, C. C., Lien, S. B., Lin, L. C., Chen, L. W., Ho, Y. J., Shen, M. C., Ho, L. J. & Lai, J. H., May 14 2018, In : International Journal of Molecular Sciences. 19, 5, 1453.

Research output: Contribution to journalArticle

Quercetin
Nitric oxide
Cartilage
Chondrocytes
arthritis
3 Citations (Scopus)

A synergistic anti-cancer effect of troglitazone and lovastatin in a human anaplastic thyroid cancer cell line and in a mouse xenograft model

Zhong, W. B., Tsai, Y. C., Chin, L. H., Tseng, J. H., Tang, L. W., Horng, S., Fan, Y. C. & Hsu, S. P., Jul 1 2018, In : International Journal of Molecular Sciences. 19, 7, 1834.

Research output: Contribution to journalArticle

troglitazone
Lovastatin
cultured cells
Heterografts
mice
7 Citations (Scopus)

Autophagic reliance promotes metabolic reprogramming in oncogenic KRAS-driven tumorigenesis

Lin, H. H., Chung, Y., Cheng, C. T., Ouyang, C., Fu, Y., Kuo, C. Y., Chi, K. K., Sadeghi, M., Chu, P., Kung, H. J., Li, C. F., Limesand, K. H. & Ann, D. K., Sep 2 2018, In : Autophagy. 14, 9, p. 1481-1498 18 p.

Research output: Contribution to journalArticle

Autophagy
Carcinogenesis
Aspartate-Ammonia Ligase
Asparagine
Neoplasms
5 Citations (Scopus)

Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) promotes EGF receptor signaling of oral squamous cell carcinoma metastasis via the complex N-glycosylation

Chiang, W. F., Cheng, T. M., Chang, C. C., Pan, S. H., Changou, C. A., Chang, T. H., Lee, K. H., Wu, S. Y., Chen, Y. F., Chuang, K. H., Shieh, D. B., Chen, Y. L., Tu, C. C., Tsui, W. L. & Wu, M. H., Jan 4 2018, In : Oncogene. 37, 1, p. 116-127 12 p.

Research output: Contribution to journalArticle

Carcinoembryonic Antigen
Cell Adhesion Molecules
Glycosylation
Epidermal Growth Factor Receptor
Squamous Cell Carcinoma
4 Citations (Scopus)

CCN6-mediated MMP-9 activation enhances metastatic potential of human chondrosarcoma

Tzeng, H. E., Tang, C. H., Wu, S. H., Chen, H. T., Fong, Y. C., Lu, Y. C., Chen, W. C., Huang, H. D., Lin, C. Y. & Wang, S. W., Oct 1 2018, In : Cell Death and Disease. 9, 10, 955.

Research output: Contribution to journalArticle

Chondrosarcoma
Metalloproteases
Neoplasm Metastasis
S 10
Cell Movement
1 Citation (Scopus)

Characterization of chicken-derived single chain antibody fragments against venom of Naja naja atra

Lee, C. H., Leu, S. J., Lee, Y. C., Liu, C. I., Lin, L. T., Mwale, P. F., Chiang, J. R., Tsai, B. Y., Chen, C. C., Hung, C. S. & Yang, Y. Y., Oct 1 2018, In : Toxins. 10, 10, 383.

Research output: Contribution to journalArticle

Cobra Venoms
Elapidae
Single-Chain Antibodies
Immunoglobulin Fragments
Venoms
2 Citations (Scopus)

Correlation between CCL4 gene polymorphisms and clinical aspects of breast cancer

Hu, G. N., Tzeng, H. E., Chen, P. C., Wang, C. Q., Zhao, Y. M., Wang, Y., Su, C. M. & Tang, C. H., Jul 30 2018, In : International Journal of Medical Sciences. 15, 11, p. 1179-1186 8 p.

Research output: Contribution to journalArticle

Single Nucleotide Polymorphism
Breast Neoplasms
Genotype
Genes
Neoplasm Metastasis

Design of diarylheptanoid derivatives as dual inhibitors against class IIa histone deacetylase and β-amyloid aggregation

Chen, L. C., Tseng, H. J., Liu, C. Y., Huang, Y. Y., Yen, C. C., Weng, J. R., Lu, Y. L., Hou, W. C., Lin, T. E., Pan, I. H., Huang, K. K., Huang, W. J. & Hsu, K. C., Jul 3 2018, In : Frontiers in Pharmacology. 9, JUL, 708.

Research output: Contribution to journalArticle

Diarylheptanoids
Histone Deacetylases
Amyloid
Alzheimer Disease
Pyrogallol
4 Citations (Scopus)

Differences in silencing of mismatched targets by sliced versus diced siRNAs

Sun, G., Wang, J., Huang, Y., Yuan, C. W. Y., Zhang, K., Hu, S., Chen, L., Lin, R. J., Yen, Y. & Riggs, A. D., Jan 1 2018, In : Nucleic Acids Research. 46, 13, p. 6806-6822 17 p.

Research output: Contribution to journalArticle

Small Interfering RNA
Argonaute Proteins
Guide RNA
RNA
RNA Interference
7 Citations (Scopus)

Dioscin overcome TKI resistance in EGFR-mutated lung adenocarcinoma cells via down-regulation of tyrosine phosphatase SHP2 expression

Wang, Y. C., Wu, D. W., Wu, T. C., Wang, L., Chen, C. Y. & Lee, H., Jan 11 2018, In : International Journal of Biological Sciences. 14, 1, p. 47-56 10 p.

Research output: Contribution to journalArticle

src Homology Domains
adenocarcinoma
Phosphoric Monoester Hydrolases
Epidermal Growth Factor Receptor
phosphatase
8 Citations (Scopus)

Discovery of aliphatic-chain hydroxamates containing indole derivatives with potent class I histone deacetylase inhibitory activities

Chao, S. W., Chen, L. C., Yu, C. C., Liu, C. Y., Lin, T. E., Guh, J. H., Wang, C. Y., Chen, C. Y., Hsu, K. C. & Huang, W. J., Jan 1 2018, In : European Journal of Medicinal Chemistry. 143, p. 792-805 14 p.

Research output: Contribution to journalArticle

Histone Deacetylases
Derivatives
Carbon
Molecular Docking Simulation
Cutaneous T-Cell Lymphoma
1 Citation (Scopus)
Epidermal Growth Factor Receptor
Protein-Tyrosine Kinases
Prostatic Neoplasms
Genes
Castration

Distributed and side-pumped fiber laser using a laser diode bar stack

Lee, Y. W., Huangfu, W. C., Li, Y. Y., Wu, I. C., Huang, S. L., Peter Liaw, S. K. & Dubinskii, M., Jan 1 2018, In : IEEE Access. 6, p. 70456-70462 7 p., 8533341.

Research output: Contribution to journalArticle

Fiber lasers
Semiconductor lasers
Pumps
Fibers
Fused silica
10 Citations (Scopus)

Dual inhibition of PIK3C3 and FGFR as a new therapeutic approach to treat bladder cancer

Chen, C. H., Changou, C. A., Hsieh, T. H., Lee, Y. C., Chu, C. Y., Hsu, K. C., Wang, H. C., Lin, Y. C., Lo, Y. N., Liu, Y. R., Liou, J. P. & Yen, Y., Mar 1 2018, In : Clinical Cancer Research. 24, 5, p. 1176-1189 14 p.

Research output: Contribution to journalArticle

Autophagy
Urinary Bladder Neoplasms
Cell Death
Therapeutics
Clustered Regularly Interspaced Short Palindromic Repeats

Effective Sirolimus Treatment for Refractory Spindle Cell Haemangioma

Ho, C. B., Hsieh, K., Chen, W. Y., Lin, Y. T., Chiou, J. F., Lee, H. L. & Shiah, H. S., May 11 2018, In : British Journal of Dermatology.

Research output: Contribution to journalArticle

Sirolimus
Hemangioma
Blood Vessels
Enchondromatosis
Therapeutics
2 Citations (Scopus)

Enhancement by Nano-Diamino-Tetrac of Antiproliferative Action of Gefitinib on Colorectal Cancer Cells: Mediation by EGFR Sialylation and PI3K Activation

Chang, T. C., Chin, Y. T., Nana, A. W., Wang, S. H., Liao, Y. M., Chen, Y. R., Shih, Y. J., Changou, C. A., Yang, Y. C. S., Wang, K., Whang-Peng, J., Wang, L. S., Stain, S. C., Shih, A., Lin, H. Y., Wu, C. H. & Davis, P. J., Jan 1 2018, (Accepted/In press) In : Hormones and Cancer.

Research output: Contribution to journalArticle

Phosphatidylinositol 3-Kinases
Colorectal Neoplasms
HCT116 Cells
Heterografts
Cell Proliferation
4 Citations (Scopus)

Fucoidan Inhibits the Proliferation of Leiomyoma Cells and Decreases Extracellular Matrix-Associated Protein Expression

Chen, H. Y., Huang, T. C., Lin, L. C., Shieh, T. M., Wu, C. H., Wang, K. L., Hong, Y. H. & Hsia, S. M., Oct 1 2018, In : Cellular Physiology and Biochemistry. 49, 5, p. 1970-1986 17 p.

Research output: Contribution to journalArticle

Extracellular Matrix Proteins
Leiomyoma
Cell Proliferation
Heterografts
Neoplasms
1 Citation (Scopus)

Generation and characterization of avian-derived anti-human CD19 single chain fragment antibodies

Tsai, K. C., Chiang, C. W., Lo, Y. N., Chang, F. L., Lin, T. Y., Chang, C. Y., Chen, W. C. & Lee, Y. C., Jan 1 2018, (Accepted/In press) In : Animal Biotechnology.

Research output: Contribution to journalArticle

Complementarity Determining Regions
Single-Chain Antibodies
Immunoglobulin Fragments
Antibodies
Chickens
2 Citations (Scopus)

Global DNA methylation analysis reveals miR-214-3p contributes to cisplatin resistance in pediatric intracranial nongerminomatous malignant germ cell tumors

Hsieh, T. H., Liu, Y. R., Chang, T. Y., Liang, M. L., Chen, H. H., Wang, H. W., Yen, Y. & Wong, T-T., Mar 27 2018, In : Neuro-Oncology. 20, 4, p. 519-530 12 p.

Research output: Contribution to journalArticle

Germ Cell and Embryonal Neoplasms
Germinoma
DNA Methylation
Cisplatin
MicroRNAs
2 Citations (Scopus)

Hepatitis B virus X protein represses LKB1 expression to promote tumor progression and poor postoperative outcome in hepatocellular carcinoma

Wu, C. C., Wu, D. W., Lin, Y. Y., Lin, P. L. & Lee, H., Jan 1 2018, (Accepted/In press) In : Surgery (United States).

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Phosphotransferases
Liver
Neoplasms
Protein Kinases
2 Citations (Scopus)

Heteronemin induces anti-Proliferation in cholangiocarcinoma cells via inhibiting TGF-β pathway

Lin, H. Y., Tey, S. L., Ho, Y., Chin, Y. T., Wang, K., Whang-Peng, J., Shih, Y. J., Chen, Y. R., Yang, Y. N., Chen, Y. C., Liu, Y. C., Tang, H. Y. & Yang, Y. C. SH., Dec 6 2018, In : Marine Drugs. 16, 12, 489.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Transforming Growth Factors
Neoplasm Metastasis
Cell Adhesion
Cell Movement
6 Citations (Scopus)

HMGB1 genetic polymorphisms are biomarkers for the development and progression of breast cancer

Huang, B. F., Tzeng, H. E., Chen, P. C., Wang, C. Q., Su, C. M., Wang, Y., Hu, G. N., Zhao, Y. M., Wang, Q. & Tang, C. H., Mar 12 2018, In : International Journal of Medical Sciences. 15, 6, p. 580-586 7 p.

Research output: Contribution to journalArticle

HMGB1 Protein
Genetic Polymorphisms
Biomarkers
Breast Neoplasms
Triple Negative Breast Neoplasms
3 Citations (Scopus)

Identification and preclinical evaluation of the small molecule, NSC745887, for treating glioblastomas via suppressing DcR3- associated signaling pathways

Fann, L. Y., Chen, Y., Chu, D. C., Weng, S. J., Chu, H. C., Wu, A. T. H., Lee, J. F., Ali, A. A. A., Chen, T. C., Huang, H. S. & Ma, K. H., Jan 1 2018, In : Oncotarget. 9, 15, p. 11922-11937 16 p.

Research output: Contribution to journalArticle

Glioblastoma
Brain Neoplasms
Caspase 3
Ataxia Telangiectasia Mutated Proteins
Staining and Labeling
Antigens
Nanofibers
Antibodies
Grafts
Semiconductor quantum dots
6 Citations (Scopus)

Influences of core morphology on electrocapacitive performance of NiCo2O4-based core/shell electrodes

Lin, L-Y., Lin, H-Y., Hong, W-L. & Lin, L-Y., 2018, In : Thin Solid Films. 667, p. 69-75 7 p.

Research output: Contribution to journalArticle

Nanowires
Nanosheets
Nickel
Energy storage
Electrodes
5 Citations (Scopus)

Inhibitory effect of Anoectochilus formosanus extract on hyperglycemia-related PD-L1 expression and cancer proliferation

Ho, Y., Chen, Y. F., Wang, L. H., Hsu, K. Y., Chin, Y. T., Yang, Y. C. S. H., Wang, S. H., Chen, Y. R., Shih, Y. J., Liu, L. F., Wang, K., Whang-Peng, J., Tang, H. Y., Lin, H. Y., Liu, H. L. & Lin, S. J., Aug 2 2018, In : Frontiers in Pharmacology. 9, AUG, 807.

Research output: Contribution to journalArticle

Obese Mice
Hyperglycemia
Blood Glucose
Metformin
Hypoglycemic Agents

Interaction of S17 antibody with the functional binding region of the hepatitis B virus pre-S2 epitope

Chang, C. Y., Chang, F. L., Chiang, C. W., Lo, Y. N., Lin, T. Y., Chen, W. C., Tsai, K. C. & Lee, Y. C., Sep 1 2018, In : Viral Immunology. 31, 7, p. 492-499 8 p.

Research output: Contribution to journalArticle

Hepatitis B virus
Epitopes
Single-Chain Antibodies
Virus Diseases
Surface Antigens
2 Citations (Scopus)

Intralymphatic Spread is a Rare Finding Associated with Poor Prognosis in Diffuse Large B-Cell Lymphoma with Extranodal Involvements

Cheng, C. L., Su, Y. C., Chao, T. Y., Lin, C. W., Chou, S. C., Yao, M., Kuo, S. H. & Yu, S. C., Jan 1 2018, In : American Journal of Surgical Pathology. 42, 5, p. 616-624 9 p.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Lymphoma
Lymphatic Vessels
Neoplasms
Survival
2 Citations (Scopus)

In tumor cells, thyroid hormone analogues non-immunologically regulate PD-L1 and PD-1 accumulation that is anti-apoptotic

Lin, H. Y., Chin, Y. T., Shih, Y. J., Chen, Y. R., Leinung, M., Keating, K. A., Mousa, S. A. & Davis, P. J., Sep 1 2018, In : Oncotarget. 9, 75, p. 34033-34037 5 p.

Research output: Contribution to journalArticle

Thyroid Hormones
Neoplasms
Lymphocytes
CD4-Positive T-Lymphocytes
Cell Surface Receptors
1 Citation (Scopus)

In vitro SUMOylation assay to study SUMO E3 ligase activity

Yang, W. S., Campbell, M., Kung, H. J. & Chang, P. C., Jan 29 2018, In : Journal of Visualized Experiments. 2018, 131, e56629.

Research output: Contribution to journalArticle

Sumoylation
Ubiquitin-Protein Ligases
Ubiquitin
Assays
Proteins
1 Citation (Scopus)

Isosteviol Derivative Inhibits Osteoclast Differentiation and Ameliorates Ovariectomy-Induced Osteoporosis

Tzeng, H. E., Huang, P. H., Tsai, C. H., Tsay, G. J., Lee, Y. J., Huang, T. J., Lin, T. H., Chiu, Y. M. & Wu, Y. Y., Dec 1 2018, In : Scientific Reports. 8, 1, 11190.

Research output: Contribution to journalArticle

Ovariectomy
Osteoclasts
Osteoporosis
Bone Resorption
Serum
30 Citations (Scopus)

Machine learning–based radiomics for molecular subtyping of gliomas

Lu, C-F., Hsu, F-T., Hsieh, KL-C., Kao, Y-CJ., Cheng, S-J., Hsu, JB-K., Tsai, P-H., Chen, R-J., Huang, C-C., Yen, Y. & Chen, C-Y., Sep 15 2018, In : Clinical Cancer Research. 24, 18, p. 4429-4436 8 p.

Research output: Contribution to journalArticle

Glioma
Isocitrate Dehydrogenase
Histology
Phenotype
Glioblastoma
5 Citations (Scopus)

Manzamine a exerts anticancer activity against human colorectal cancer cells

Lin, L. C., Kuo, T. T., Chang, H. Y., Liu, W. S., Hsia, S. M. & Huang, T. C., Jul 29 2018, In : Marine Drugs. 16, 8, 252.

Research output: Contribution to journalArticle

Human Activities
Colorectal Neoplasms
Porifera
HCT116 Cells
Carbolines
12 Citations (Scopus)

MicroRNA-19a and microRNA-19b promote the malignancy of clear cell renal cell carcinoma through targeting the tumor suppressor RhoB

Niu, S., Ma, X., Zhang, Y., Liu, Y. N., Chen, X., Gong, H., Yao, Y., Liu, K. & Zhang, X., Feb 1 2018, In : PLoS One. 13, 2, e0192790.

Research output: Contribution to journalArticle

kidney cells
MicroRNAs
microRNA
Renal Cell Carcinoma
carcinoma
8 Citations (Scopus)

MicroRNA-630 may confer favorable cisplatin-based chemotherapy and clinical outcomes in non-small cell lung cancer by targeting Bcl-2

Chen, M. J., Wu, D. W., Wang, G. C., Wang, Y. C., Chen, C. Y. & Lee, H., Jan 1 2018, In : Oncotarget. 9, 17, p. 13758-13767 10 p.

Research output: Contribution to journalArticle

MicroRNAs
Non-Small Cell Lung Carcinoma
Cisplatin
Drug Therapy
Inhibitory Concentration 50
5 Citations (Scopus)

miR-211 regulates the expression of RRM2 in tumoral metastasis and recurrence in colorectal cancer patients with a k-ras gene mutation

Chang, C. C., Lin, C. C., Wang, C. H., Huang, C. C., Ke, T. W., Wei, P. L., Yeh, K. T., Hsu, K. C., Hsu, N. Y. & Cheng, Y. W., May 1 2018, In : Oncology Letters. 15, 5, p. 8107-8117 11 p.

Research output: Contribution to journalArticle

ras Genes
MicroRNAs
Colorectal Neoplasms
Neoplasm Metastasis
Recurrence
5 Citations (Scopus)

Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers

Nana, A. W., Wu, S. Y., Yang, Y. C. S., Chin, Y. T., Cheng, T. M., Ho, Y., Li, W. S., Liao, Y. M., Chen, Y. R., Shih, Y. J., Liu, Y. R., Pedersen, J., Incerpi, S., Hercbergs, A., Liu, L. F., Whang-Peng, J., Davis, P. J. & Lin, H. Y., Oct 1 2018, In : Hormones and Cancer. 9, 5, p. 349-360 12 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Oxidoreductases
Neoplasms
Integrins
Stilbenes
7 Citations (Scopus)

Nano-diamino-tetrac (NDAT) inhibits PD-L1 expression which is essential for proliferation in oral cancer cells

Lin, S. J., Chin, Y. T., Ho, Y., Chou, S. Y., Sh Yang, Y. C., Nana, A. W., Su, K. W., Lim, Y. T., Wang, K., Lee, SY. Y., Shih, Y. J., Chen, Y. R., Whang-Peng, J., Davis, P. J., Lin, H. Y. & Fu, E., Oct 1 2018, In : Food and Chemical Toxicology. 120, p. 1-11 11 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Cells
death
Ligands
phosphatidylinositol 3-kinase
4 Citations (Scopus)

Novel technique for repairing posterior medial meniscus root tears using porcine knees and biomechanical study

Wu, J. L., Lee, C. H., Yang, C. T., Chang, C. M., Li, G., Cheng, C. K., Chen, C. H., Huang, H. S. & Lai, Y. S., Feb 1 2018, In : PLoS One. 13, 2, e0192027.

Research output: Contribution to journalArticle

Tibial Meniscus
knees
Tendons
sutures
Tears
8 Citations (Scopus)

PD-L1 confers resistance to EGFR mutation-independent tyrosine kinase inhibitors in non-small cell lung cancer via upregulation of YAP1 expression

Tung, J. N., Lin, P. L., Wang, Y. C., Wu, D. W., Chen, C. Y. & Lee, H., Jan 1 2018, In : Oncotarget. 9, 4, p. 4637-4646 10 p.

Research output: Contribution to journalArticle

Non-Small Cell Lung Carcinoma
Protein-Tyrosine Kinases
Up-Regulation
Mutation
Gene Expression
4 Citations (Scopus)

Phase IB trial of ixabepilone and vorinostat in metastatic breast cancer

Luu, T., Kim, K. P., Blanchard, S., Anyang, B., Hurria, A., Yang, L., Beumer, J. H., Somlo, G. & Yen, Y., Jan 1 2018, In : Breast Cancer Research and Treatment. 167, 2, p. 469-478 10 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Maximum Tolerated Dose
Pharmacokinetics
Neutropenia
Appointments and Schedules
Oxylipins
Galactolipids
Capillary Permeability
Melanoma
Neoplasm Metastasis