Ph.D. Program for Cancer Molecular Biology and Drug Discovery

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output 1996 2020

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Article
6 Citations (Scopus)
Cholangiocarcinoma
Case-Control Studies
Diabetes Mellitus
Population
Cholecystectomy
2 Citations (Scopus)

Intralymphatic Spread is a Rare Finding Associated with Poor Prognosis in Diffuse Large B-Cell Lymphoma with Extranodal Involvements

Cheng, C. L., Su, Y. C., Chao, T. Y., Lin, C. W., Chou, S. C., Yao, M., Kuo, S. H. & Yu, S. C., Jan 1 2018, In : American Journal of Surgical Pathology. 42, 5, p. 616-624 9 p.

Research output: Contribution to journalArticle

Lymphoma, Large B-Cell, Diffuse
Lymphoma
Lymphatic Vessels
Neoplasms
Survival
2 Citations (Scopus)

In tumor cells, thyroid hormone analogues non-immunologically regulate PD-L1 and PD-1 accumulation that is anti-apoptotic

Lin, H. Y., Chin, Y. T., Shih, Y. J., Chen, Y. R., Leinung, M., Keating, K. A., Mousa, S. A. & Davis, P. J., Sep 1 2018, In : Oncotarget. 9, 75, p. 34033-34037 5 p.

Research output: Contribution to journalArticle

Thyroid Hormones
Neoplasms
Lymphocytes
CD4-Positive T-Lymphocytes
Cell Surface Receptors

In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells

Chen, J. C., Hsieh, Y. Y., Lo, H. L., Li, A., Chou, C. J. & Yang, P. M., Sep 9 2019, In : Biomolecules. 9, 9

Research output: Contribution to journalArticle

Open Access
Drug Resistance
Computer Simulation
Colorectal Neoplasms
Etoposide
Topoisomerase Inhibitors
4 Citations (Scopus)

In vitro and in vivo anti-tumour effects of MPT0B014, a novel derivative aroylquinoline, and in combination with erlotinib in human non-small-cell lung cancer cells

Tsai, A. C., Pai, H. C., Wang, C. Y., Liou, J. P., Teng, C. M., Wang, J. C. & Pan, S. L., Jan 2014, In : British Journal of Pharmacology. 171, 1, p. 122-133 12 p.

Research output: Contribution to journalArticle

P-Glycoprotein
Non-Small Cell Lung Carcinoma
lissamine rhodamine B
Neoplasms
Cyclin B1
1 Citation (Scopus)

In vitro SUMOylation assay to study SUMO E3 ligase activity

Yang, W. S., Campbell, M., Kung, H. J. & Chang, P. C., Jan 29 2018, In : Journal of Visualized Experiments. 2018, 131, e56629.

Research output: Contribution to journalArticle

Sumoylation
Ubiquitin-Protein Ligases
Ubiquitin
Assays
Proteins
29 Citations (Scopus)

Isoliquiritigenin induces apoptosis and autophagy and inhibits endometrial cancer growth in mice

Wu, C-H., Chen, H. Y., Wang, C-W., Shieh, T. M., Huang, T-C., Lin, L. C., Wang, K. L. & Hsia, S-M., 2016, In : Oncotarget. 7, 45, p. 73432-73447 16 p.

Research output: Contribution to journalArticle

Autophagy
Endometrial Neoplasms
Apoptosis
Growth
Neoplasms
15 Citations (Scopus)

Isoliquiritigenin induces autophagy and inhibits ovarian cancer cell growth

Chen, H. Y., Huang, T. C., Shieh, T. M., Wu, C. H., Lin, L. C. & Hsia, S. M., Oct 1 2017, In : International Journal of Molecular Sciences. 18, 10, 2025.

Research output: Contribution to journalArticle

Autophagy
Cell growth
Ovarian Neoplasms
cancer
Fluorescence
1 Citation (Scopus)

Isosteviol Derivative Inhibits Osteoclast Differentiation and Ameliorates Ovariectomy-Induced Osteoporosis

Tzeng, H. E., Huang, P. H., Tsai, C. H., Tsay, G. J., Lee, Y. J., Huang, T. J., Lin, T. H., Chiu, Y. M. & Wu, Y. Y., Dec 1 2018, In : Scientific Reports. 8, 1, 11190.

Research output: Contribution to journalArticle

Ovariectomy
Osteoclasts
Osteoporosis
Bone Resorption
Serum

Jejunal Cancer with WRN Mutation Identified from Next-Generation Sequencing: A Case Study and Minireview

Chang, C., Shiah, H-S., Hsu, N-Y., Huang, H. Y., Chu, J-S. & Yen, Y., 2014, In : Case Reports in Surgery.

Research output: Contribution to journalArticle

Jejunal Neoplasms
Jejunum
Mutation
Small Intestine
Exome
8 Citations (Scopus)

KDM8/JMJD5 as a dual coactivator of AR and PKM2 integrates AR/EZH2 network and tumor metabolism in CRPC

Wang, H. J., Pochampalli, M., Wang, L. Y., Zou, J. X., Li, P. S., Hsu, S. C., Wang, B. J., Huang, S. H., Yang, P., Yang, J. C., Chu, C. Y., Hsieh, C. L., Sung, S. Y., Li, C. F., Tepper, C. G., Ann, D. K., Gao, A. C., Evans, C. P., Izumiya, Y., Chuu, C. P. & 3 others, Wang, W. C., Chen, H. W. & Kung, H. J., Jan 3 2019, In : Oncogene. 38, 1, p. 17-32

Research output: Contribution to journalArticle

Pyruvate Kinase
Androgen Receptors
Androgens
Castration
Prostatic Neoplasms

KLF4 functions as an activator of the androgen receptor through reciprocal feedback

Siu, M-K., Suau, F., Chen, W-Y., Tsai, Y-C., Tsai, H-Y., Yeh, H-L. & Liu, Y-N., Dec 2016, In : Oncogenesis. 5, 12, p. e282

Research output: Contribution to journalArticle

Activator Appliances
Androgen Receptors
MicroRNAs
Prostatic Neoplasms
Neoplasm Metastasis
16 Citations (Scopus)

KLHL39 suppresses colon cancer metastasis by blocking KLHL20-mediated PML and DAPK ubiquitination

Chen, H. Y., Hu, J. Y., Chen, T. H., Lin, Y. C., Liu, X., Lin, M. Y., Lang, Y. D., Yen, Y. & Chen, R. H., Oct 1 2015, In : Oncogene. 34, 40, p. 5141-5151 11 p.

Research output: Contribution to journalArticle

Death-Associated Protein Kinases
Cullin Proteins
Ubiquitination
Colonic Neoplasms
Neoplasm Metastasis
4 Citations (Scopus)

Krüpple-like factor 10 regulates radio-sensitivity of pancreatic cancer via UV radiation resistance-associated gene

Chang, V. H. S., Tsai, Y. C., Tsai, Y. L., Peng, S. L., Chen, S. L., Chang, T. M., Yu, W. C. Y. & Ch'ang, H. J., Mar 1 2017, In : Radiotherapy and Oncology. 122, 3, p. 476-484

Research output: Contribution to journalArticle

Radio
Pancreatic Neoplasms
Radiation
Genes
Autophagy
13 Citations (Scopus)

Lanatoside C, a cardiac glycoside, acts through protein kinase Cδ to cause apoptosis of human hepatocellular carcinoma cells

Chao, M. W., Chen, T. H., Huang, H. L., Chang, Y. W., HuangFu, W. C., Lee, Y. C., Teng, C. M. & Pan, S. L., Apr 7 2017, In : Scientific Reports. 7, 46134.

Research output: Contribution to journalArticle

Cardiac Glycosides
Protein Kinase C
Hepatocellular Carcinoma
Apoptosis
Digitalis
24 Citations (Scopus)

Landscape of Pin1 in the cell cycle

Lin, C. H., Li, H. Y., Lee, Y. C., Calkins, M. J., Lee, K. H., Yang, C. N. & Lu, P. J., Mar 25 2015, In : Experimental Biology and Medicine. 240, 3, p. 403-408 6 p.

Research output: Contribution to journalArticle

Cell Cycle
Cells
Substrates
Peptidylprolyl Isomerase
Cyclin E

Leptin-derived peptides block leptin-induced proliferation by reducing expression of pro-inflammatory genes in hepatocellular carcinoma cells

Ho, Y., Wang, S. H., Chen, Y. R., Li, Z. L., Chin, Y. T., Yang, Y. C. S. H., Wu, Y. H., Su, K. W., Chu, H. R., Chiu, H. C., Crawford, D. R., Shih, Y. J., Grasso, P., Tang, H. Y., Lin, H. Y., Davis, P. J., Whang-Peng, J. & Wang, K., Nov 1 2019, In : Food and Chemical Toxicology. 133, p. 110808 110808.

Research output: Contribution to journalArticle

leptin (116-130)
hepatoma
Leptin
leptin
Hepatocellular Carcinoma
9 Citations (Scopus)

Leptin OB3 peptide suppresses leptin-induced signaling and progression in ovarian cancer cells

Chin, Y. T., Wang, L. M., Hsieh, M. T., Shih, Y. J., Nana, A. W., Changou, C. A., Yang, Y. C. S. H., Chiu, H. C., Fu, E., Davis, P. J., Tang, H. Y. & Lin, H. Y., Jul 27 2017, In : Journal of Biomedical Science. 24, 1, 51.

Research output: Contribution to journalArticle

leptin (116-130)
Leptin
Ovarian Neoplasms
Cells
Estrogen Receptors
1 Citation (Scopus)

Leukemia Inhibitory Factor Promotes Castration-resistant Prostate Cancer and Neuroendocrine Differentiation by Activated ZBTB46

Liu, Y-N., Niu, S., Chen, W-Y., Zhang, Q., Tao, Y., Chen, W-H., Jiang, K-C., Chen, X., Shi, H., Liu, A., Li, J., Li, Y., Lee, Y-C., Zhang, X. & Huang, J., Apr 8 2019, In : Clinical cancer research : an official journal of the American Association for Cancer Research.

Research output: Contribution to journalArticle

Leukemia Inhibitory Factor
Castration
Prostatic Neoplasms
Androgens
Therapeutics
17 Citations (Scopus)

LKB1 Loss at Transcriptional Level Promotes Tumor Malignancy and Poor Patient Outcomes in Colorectal Cancer

He, T. Y., Tsai, L. H., Huang, C. C., Chou, M. C. & Lee, H., 2014, In : Annals of Surgical Oncology. 21, 4, p. 703-710 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Phosphotransferases
Liver
Neoplasms
Sirolimus
19 Citations (Scopus)

LKB1 loss by alteration of the NKX2-1/p53 pathway promotes tumor malignancy and predicts poor survival and relapse in lung adenocarcinomas

Tsai, L. H., Chen, P. M., Cheng, Y. W., Chen, C. Y., Sheu, G. T., Wu, T. C. & Lee, H., Jul 17 2014, In : Oncogene. 33, 29, p. 3851-3860 10 p.

Research output: Contribution to journalArticle

Recurrence
Survival
Neoplasms
Adenocarcinoma of lung
Lung
5 Citations (Scopus)

LncRNA NORAD is repressed by the YAP pathway and suppresses lung and breast cancer metastasis by sequestering S100P

Tan, B. S., Yang, M. C., Singh, S., Chou, Y. C., Chen, H. Y., Wang, M. Y., Wang, Y. C. & Chen, R. H., Jan 1 2019, In : Oncogene.

Research output: Contribution to journalArticle

Lung Neoplasms
Long Noncoding RNA
Breast Neoplasms
Neoplasm Metastasis
Mi-2 Nucleosome Remodeling and Deacetylase Complex
46 Citations (Scopus)

Long noncoding RNA LncHIFCAR/MIR31HG is a HIF-1α co-activator driving oral cancer progression

Shih, J. W., Chiang, W. F., Wu, A. T. H., Wu, M. H., Wang, L. Y., Yu, Y. L., Hung, Y. W., Wang, W. C., Chu, C. Y., Hung, C. L., Changou, C. A., Yen, Y. & Kung, H. J., Jun 22 2017, In : Nature Communications. 8, 15874.

Research output: Contribution to journalArticle

Long Noncoding RNA
Mouth Neoplasms
progressions
hypoxia
cancer
30 Citations (Scopus)

Loss of androgen-regulated MicroRNA 1 activates SRC and promotes prostate cancer bone metastasis

Liu, Y. N., Yin, J., Barrett, B., Sheppard-Tillman, H., Li, D., Casey, O. M., Fang, L., Hynes, P. G., Ameri, A. H. & Kelly, K., 2015, In : Molecular and Cellular Biology. 35, 11, p. 1940-1951 12 p.

Research output: Contribution to journalArticle

Bone Neoplasms
MicroRNAs
Androgens
Prostatic Neoplasms
Neoplasm Metastasis
36 Citations (Scopus)

Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance

Siu, M. K., Abou-Kheir, W., Yin, J. J., Chang, Y. S., Barrett, B., Suau, F., Casey, O., Chen, W. Y., Fang, L., Hynes, P., Hsieh, Y. Y., Liu, Y. N., Huang, J. & Kelly, K., 2014, In : Oncotarget. 5, 11, p. 3770-3784 15 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Protein-Tyrosine Kinases
Prostatic Neoplasms
Neoplasm Metastasis
Apoptosis Regulatory Proteins
19 Citations (Scopus)

Loss of SPDEF and gain of TGFBI activity after androgen deprivation therapy promote EMT and bone metastasis of prostate cancer

Chen, W. Y., Tsai, Y. C., Yeh, H. L., Suau, F., Jiang, K. C., Shao, A. N., Huang, J. & Liu, Y. N., Aug 15 2017, In : Science Signaling. 10, 492, eaam6826.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Androgens
Prostatic Neoplasms
Bone
Androgen Receptors
33 Citations (Scopus)

Loss of TIMP-3 promotes tumor invasion via elevated IL-6 production and predicts poor survival and relapse in HPV-infected non-small cell lung cancer

Wu, D. W., Tsai, L. H., Chen, P. M., Lee, M. C., Wang, L., Chen, C. Y., Cheng, Y. W. & Lee, H., Nov 2012, In : American Journal of Pathology. 181, 5, p. 1796-1806 11 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-3
Non-Small Cell Lung Carcinoma
Interleukin-6
Recurrence
Survival
14 Citations (Scopus)

Lovastatin overcomes gefitinib resistance through TNF-a signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo

Yang, S. H., Lin, H. Y., Chang, V. H. S., Chen, C. C., Liu, Y. R., Wang, J., Zhang, K., Jiang, X. & Yen, Y., 2015, In : Oncotarget. 6, 27, p. 23857-23873 17 p.

Research output: Contribution to journalArticle

Lovastatin
Cholangiocarcinoma
Heterografts
In Vitro Techniques
gefitinib
16 Citations (Scopus)

Low/negative expression of DDX3 might predict poor prognosis in non-smoker patients with oral cancer

Lee, C. H., Lin, S. H., Yang, S. F., Yang, S. M., Chen, M. K., Lee, H., Ko, J. L., Chen, C. J. & Yeh, K. T., Jan 2014, In : Oral Diseases. 20, 1, p. 76-83 8 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Squamous Cell Carcinoma
Neoplasms
Survival
Mastication
18 Citations (Scopus)

Lowered circulating aspartate is a metabolic feature of human breast cancer

Xie, G., Zhou, B., Zhao, A., Qiu, Y., Zhao, X., Garmire, L., Shvetsov, Y. B., Yu, H., Yen, Y. & Jia, W., Jan 1 2015, In : Oncotarget. 6, 32, p. 33369-33381 13 p.

Research output: Contribution to journalArticle

Aspartic Acid
Breast Neoplasms
Neoplasms
Cell Line
Metabolomics
17 Citations (Scopus)

Low thyroid hormone levels improve survival in murine model for ocular melanoma

Fabian, I. D., Rosner, M., Fabian, I., Vishnevskia-Dai, V., Zloto, O., Maman, E. S., Cohen, K., Ellis, M., Lin, H. Y., Hercbergs, A., Davis, P. J. & Ashur-Fabian, O., 2015, In : Oncotarget. 6, 13, p. 11038-11046 9 p.

Research output: Contribution to journalArticle

Thyroid Hormones
Melanoma
Propylthiouracil
Thyroxine
Hyperthyroidism
5 Citations (Scopus)

LTP-1, a novel antimitotic agent and Stat3 inhibitor, inhibits human pancreatic carcinomas in vitro and in vivo

Huang, H. L., Chao, M. W., Chen, C. C., Cheng, C. C., Chen, M. C., Lin, C. F., Liou, J. P., Teng, C. M. & Pan, S. L., Jun 9 2016, In : Scientific Reports. 6, 27794.

Research output: Contribution to journalArticle

Antimitotic Agents
Pancreatic Neoplasms
Polyploidy
Microtubules
Growth
32 Citations (Scopus)

Machine learning–based radiomics for molecular subtyping of gliomas

Lu, C-F., Hsu, F-T., Hsieh, KL-C., Kao, Y-CJ., Cheng, S-J., Hsu, JB-K., Tsai, P-H., Chen, R-J., Huang, C-C., Yen, Y. & Chen, C-Y., Sep 15 2018, In : Clinical Cancer Research. 24, 18, p. 4429-4436 8 p.

Research output: Contribution to journalArticle

Glioma
Isocitrate Dehydrogenase
Histology
Phenotype
Glioblastoma
6 Citations (Scopus)

Manzamine a exerts anticancer activity against human colorectal cancer cells

Lin, L. C., Kuo, T. T., Chang, H. Y., Liu, W. S., Hsia, S. M. & Huang, T. C., Jul 29 2018, In : Marine Drugs. 16, 8, 252.

Research output: Contribution to journalArticle

Human Activities
Colorectal Neoplasms
Porifera
HCT116 Cells
Carbolines
5 Citations (Scopus)

Markers for efficacy of mammalian target of rapamycin inhibitor

Liao, Y. M., Sy, A. & Yen, Y., Oct 2012, In : Anticancer Research. 32, 10, p. 4235-4244 10 p.

Research output: Contribution to journalArticle

Sirolimus
Intercellular Signaling Peptides and Proteins
Carcinogenesis
Biomarkers
Proteins

Mechanism and clinical properties of stembios cell therapy: Induction of early osseointegration in novel dental implants

Weng, C. C., Ou, K. L., Wu, C. Y., Huang, Y. H., Wang, J., Yen, Y., Cheng, H. Y. & Lin, Y. H., 2017, In : International Journal of Oral and Maxillofacial Implants. 32, 1, p. e47-e54

Research output: Contribution to journalArticle

Osseointegration
Dental Implants
Cell- and Tissue-Based Therapy
Bone and Bones
Atomic Force Microscopy
27 Citations (Scopus)

Mechanisms of ceramide-induced COX-2-dependent apoptosis in human ovarian cancer OVCAR-3 cells partially overlapped with resveratrol

Lin, H. Y., Delmas, D., Vang, O., Hsieh, T. C., Lin, S., Cheng, G. Y., Chiang, H. L., Chen, C. E., Tang, H. Y., Crawford, D. R., Whang-Peng, J., Hwang, J., Liu, L. F. & Wu, J. M., Aug 2013, In : Journal of Cellular Biochemistry. 114, 8, p. 1940-1954 15 p.

Research output: Contribution to journalArticle

Ceramides
Cyclooxygenase 2
Ovarian Neoplasms
Apoptosis
Caspase 7
24 Citations (Scopus)

Mechanisms of dihydrotestosterone action on resveratrolinduced anti-proliferation in breast cancer cells with different ER status

Chin, Y. T., Yang, S. H., Chang, T. C., Changou, C. A., Lai, H. Y., Fu, E., HuangFu, W. C., Davis, P. J., Lin, H. Y. & Liu, L. F., 2015, In : Oncotarget. 6, 34, p. 35866-35879 14 p.

Research output: Contribution to journalArticle

Dihydrotestosterone
Breast Neoplasms
Apoptosis
p53 Genes
Integrins
1 Citation (Scopus)

Melatonin activates cell death programs for the suppression of uterine leiomyoma cell proliferation

Lin, P. H., Tung, Y. T., Chen, H. Y., Chiang, Y. F., Hong, H. C., Huang, K. C., Hsu, S. P., Huang, T. C. & Hsia, S. M., Jan 1 2020, In : Journal of Pineal Research. 68, 1, e12620.

Research output: Contribution to journalArticle

Leiomyoma
Melatonin
Cell Death
Cell Proliferation
Myometrium
37 Citations (Scopus)

Metabolism and mis-metabolism of the neuropathological signature protein TDP-43

Huang, C. C., Bose, J. K., Majumder, P., Lee, K. H., Huang, J. T. J., Huang, J. K. & Shen, C. K. J., 2014, In : Journal of Cell Science. 127, 14, p. 3024-3038 15 p.

Research output: Contribution to journalArticle

TDP-43 Proteinopathies
Autophagy
Caspases
Frontotemporal Lobar Degeneration
Proteins
5 Citations (Scopus)

Methyl Protodioscin, a Steroidal Saponin, Inhibits Neointima Formation in Vitro and in Vivo

Chung, Y. L., Pan, C. H., Wang, C. C. N., Hsu, K. C., Sheu, M. J., Chen, H. F. & Wu, C. H., Jun 24 2016, In : Journal of Natural Products. 79, 6, p. 1635-1644 10 p.

Research output: Contribution to journalArticle

Neointima
Saponins
Vascular Smooth Muscle
Smooth Muscle Myocytes
Muscle
23 Citations (Scopus)

MicroRNA-184 Deregulated by the MicroRNA-21 Promotes Tumor Malignancy and Poor Outcomes in Non-small Cell Lung Cancer via Targeting CDC25A and c-Myc

Lin, T. C., Lin, P. L., Cheng, Y. W., Wu, T. C., Chou, M. C., Chen, C. Y. & Lee, H., Dec 1 2015, In : Annals of Surgical Oncology. 22, p. 1532-1539 8 p.

Research output: Contribution to journalArticle

MicroRNAs
Non-Small Cell Lung Carcinoma
Neoplasms
Messenger RNA
Survival
49 Citations (Scopus)

MicroRNA-18a is elevated in prostate cancer and promotes tumorigenesis through suppressing STK4 in vitro and in vivo

Hsu, T. I., Hsu, C. H., Lee, K. H., Lin, J. T., Chen, C. S., Chang, K. C., Su, C. Y. J., Hsiao, M. & Lu, P. J., Jan 1 2014, In : Oncogenesis. 3, 4, e99.

Research output: Contribution to journalArticle

Protein-Serine-Threonine Kinases
MicroRNAs
Prostatic Neoplasms
Carcinogenesis
Neoplasms
12 Citations (Scopus)

MicroRNA-19a and microRNA-19b promote the malignancy of clear cell renal cell carcinoma through targeting the tumor suppressor RhoB

Niu, S., Ma, X., Zhang, Y., Liu, Y. N., Chen, X., Gong, H., Yao, Y., Liu, K. & Zhang, X., Feb 1 2018, In : PLoS One. 13, 2, e0192790.

Research output: Contribution to journalArticle

kidney cells
MicroRNAs
microRNA
Renal Cell Carcinoma
carcinoma
26 Citations (Scopus)

MicroRNA-21 promotes tumour malignancy via increased nuclear translocation of β-catenin and predicts poor outcome in APC-mutated but not in APC-wild-type colorectal cancer

Lin, P. L., Wu, D. W., Huang, C. C., He, T. Y., Chou, M. C., Sheu, G. T. & Lee, H., Oct 1 2014, In : Carcinogenesis. 35, 10, p. 2175-2182 8 p.

Research output: Contribution to journalArticle

Catenins
Adenomatous Polyposis Coli
MicroRNAs
Colorectal Neoplasms
Neoplasms
34 Citations (Scopus)

MicroRNA-224 suppresses colorectal cancer cell migration by targeting Cdc42

Ke, T. W., Hsu, H. L., Wu, Y. H., Chen, W. T. L., Cheng, Y. W. & Cheng, C. W., 2014, In : Disease Markers. 2014, 617150.

Research output: Contribution to journalArticle

MicroRNAs
Cell Movement
Colorectal Neoplasms
Cells
Tissue
60 Citations (Scopus)

MicroRNA-296-5p (miR-296-5p) functions as a tumor suppressor in prostate cancer by directly targeting Pin1

Lee, K. H., Lin, F. C., Hsu, T. I., Lin, J. T., Guo, J. H., Tsai, C. H., Lee, Y. C., Lee, Y. C., Chen, C. L., Hsiao, M. & Lu, P. J., 2014, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1843, 9, p. 2055-2066 12 p.

Research output: Contribution to journalArticle

MicroRNAs
Prostatic Neoplasms
Neoplasms
3' Untranslated Regions
Cell Line
149 Citations (Scopus)

MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway

Hsieh, I. S., Chang, K. C., Tsai, Y. T., Ke, J. Y., Lu, P. J., Lee, K. H., Yeh, S. D., Hong, T. M. & Chen, Y. L., Mar 2013, In : Carcinogenesis. 34, 3, p. 530-538 9 p.

Research output: Contribution to journalArticle

Wnt Signaling Pathway
MicroRNAs
Prostatic Neoplasms
Stem Cells
Down-Regulation
64 Citations (Scopus)

MicroRNA-34a regulates WNT/TCF7 signaling and inhibits bone metastasis in Ras-activated prostate cancer

Chen, W. Y., Liu, S. Y., Chang, Y. S., Yin, J. J., Yeh, H. L., Mouhieddine, T. H., Hadadeh, O., Abou-Kheir, W. & Liu, Y. N., 2015, In : Oncotarget. 6, 1, p. 441-457 17 p.

Research output: Contribution to journalArticle

MicroRNAs
Prostatic Neoplasms
Neoplasm Metastasis
Bone and Bones
3' Untranslated Regions
8 Citations (Scopus)

MicroRNA-630 may confer favorable cisplatin-based chemotherapy and clinical outcomes in non-small cell lung cancer by targeting Bcl-2

Chen, M. J., Wu, D. W., Wang, G. C., Wang, Y. C., Chen, C. Y. & Lee, H., Jan 1 2018, In : Oncotarget. 9, 17, p. 13758-13767 10 p.

Research output: Contribution to journalArticle

MicroRNAs
Non-Small Cell Lung Carcinoma
Cisplatin
Drug Therapy
Inhibitory Concentration 50