Ph.D. Program for Cancer Molecular Biology and Drug Discovery

Research output

Research output per year 1986 2021

• 35429 Citations
• 78 h-Index
• 1549 Article
• 69 Review article
• 35 Comment/debate
• 35 Patent
• 48 More
  • 12 Conference contribution
  • 11 Book
  • 10 Chapter
  • 4 Letter
  • 3 Erratum
  • 2 Chapter (peer-reviewed)
  • 2 Paper
  • 1 Anthology
  • 1 Poster
  • 1 Editorial
  • 1 Short survey

Research output per year

Research output per year

Search results

• 2021

  2,3,5,4′-Tetrahydroxystilbene-2-O-β-d-glucoside promotes the effects of dental pulp stem cells on rebuilding periodontal tissues in experimental periodontal defects

  Lin, C. Y., Tsai, M. S., Kuo, P. J., Chin, Y. T., Weng, I. T., Wu, Y., Huang, H. M., Hsiung, C. N., Lin, H. Y. & Lee, S. Y., Feb 2021, In: Journal of Periodontology. 92, 2, p. 306-316 11 p.

  Research output: Contribution to journal › Article › peer-review

  • 2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside
  • Dental Pulp
  • Stem Cells
  • X-Ray Microtomography
  • Osteogenesis

• An annotation-free whole-slide training approach to pathological classification of lung cancer types using deep learning

  Chen, C. L., Chen, C. C., Yu, W. H., Chen, S. H., Chang, Y. C., Hsu, T. I., Hsiao, M., Yeh, C. Y. & Chen, C. Y., Dec 2021, In: Nature Communications. 12, 1, 1193.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • annotations
  • Deep Learning
  • learning
  • lungs
  • chutes
  1 Citation (Scopus)

• An integrated bioinformatics study of a novel niclosamide derivative, nsc765689, a potential gsk3β/β-catenin /stat3/ cd44 suppressor with anti-glioblastoma properties

  Mokgautsi, N., Wen, Y. T., Lawal, B., Khedkar, H., Sumitra, M. R., Wu, A. T. H. & Huang, H. S., Mar 1 2021, In: International journal of molecular sciences. 22, 5, p. 1-23 23 p., 2464.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Glycogen
  • Niclosamide
  • glycogens
  • suppressors
  • Glycogen Synthase Kinase 3
  1 Citation (Scopus)

• A novel dual HDAC and HSP90 inhibitor, MPT0G449, downregulates oncogenic pathways in human acute leukemia in vitro and in vivo

  Wu, Y. W., Chao, M. W., Tu, H. J., Chen, L. C., Hsu, K. C., Liou, J. P., Yang, C. R., Yen, S. C., HuangFu, W. C. & Pan, S. L., May 2021, In: Oncogenesis. 10, 5, 39.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Histone Deacetylase Inhibitors
  • Leukemia
  • Down-Regulation
  • In Vitro Techniques
  • Mitogen-Activated Protein Kinase Kinases

• A novel histone deacetylase inhibitor MPT0L184 dysregulates cell-cycle checkpoints and initiates unscheduled mitotic signaling

  Chang, T. Y., Nepali, K., Chen, Y. Y., Yang, Y. C. S. H., Hsu, K. C., Yen, Y., Pan, S. L., Liou, J. P. & Lee, S. B., Jun 2021, In: Biomedicine and Pharmacotherapy. 138, 111485.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Histone Deacetylase Inhibitors
  • Histone Deacetylases
  • Cell Cycle Checkpoints
  • Mitosis
  • Epigenomics

• Association between arsenic exposure, DNA damage, and urological cancers incidence: A long-term follow-up study of residents in an arseniasis endemic area of northeastern Taiwan

  Tsai, T. L., Kuo, C. C., Hsu, L. I., Tsai, S. F., Chiou, H. Y., Chen, C. J., Hsu, K. H. & Wang, S. L., Mar 2021, In: Chemosphere. 266, 129094.

  Research output: Contribution to journal › Article › peer-review

  • Arsenic
  • Urologic Neoplasms
  • DNA
  • Taiwan
  • cancer

• Association between dietary patterns and serum hepatic enzyme levels in adults with dyslipidemia and impaired fasting plasma glucose

  Lin, L. Y., Hsu, C. Y., Chiou, H. Y., Lee, H. A., Hsu, L. M., Chang, P. Y., Kurniawan, A. L. & Chao, J. C. J., Mar 2021, In: Nutrients. 13, 3, p. 1-17 17 p., 987.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • hyperlipidemia
  • eating habits
  • Western Diet
  • Dyslipidemias
  • fasting

• Author Correction: Comparison of clinical outcomes between laparoscopic and open surgery for left-sided colon cancer: a nationwide population-based study (Scientific Reports, (2020), 10, 1, (75), 10.1038/s41598-019-57059-6)

  Huang, Y. M., Lee, Y. W., Huang, Y. J. & Wei, P. L., Dec 2021, In: Scientific Reports. 11, 1, 9084.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Laparoscopy
  • Colonic Neoplasms
  • Population

• CAP rigidification of MS-275 and chidamide leads to enhanced antiproliferative effects mediated through HDAC1, 2 and tubulin polymerization inhibition

  Singh, A., Chang, T. Y., Kaur, N., Hsu, K. C., Yen, Y., Lin, T. E., Lai, M. J., Lee, S. B. & Liou, J. P., Apr 5 2021, In: European Journal of Medicinal Chemistry. 215, 113169.

  Research output: Contribution to journal › Article › peer-review

  • N-(2-amino-5-fluorobenzyl)-4-(N-(pyridine-3-acrylyl)aminomethyl)benzamide
  • Anilides
  • entinostat
  • Polymerization
  • Tubulin
  2 Citations (Scopus)

• CCDC167 as a potential therapeutic target and regulator of cell cycle-related networks in breast cancer

  Chen, P. S., Hsu, H. P., Phan, N. N., Yen, M. C., Chen, F. W., Liu, Y. W., Lin, F. P., Feng, S. Y., Cheng, T. L., Yeh, P. H., Omar, H. A., Sun, Z., Jiang, J. Z., Chan, Y. S., Lai, M. D., Wang, C. Y. & Hung, J. H., Feb 15 2021, In: Aging. 13, 3, p. 4157-4181 25 p.

  Research output: Contribution to journal › Article › peer-review

  • Protein Domains
  • Cell Cycle
  • Breast Neoplasms
  • Estrogen Receptors
  • Therapeutics
  3 Citations (Scopus)

• Chemoradiotherapy for Inoperable Carotid Body Leiomyosarcoma: A Case Report and Review of Literature

  Liu, C. S., Tsai, J. R., Kao, Y. T., Lu, L. S., Chen, Y. J., Burnouf, T., Wang, P. Y., Chiou, J. F. & Ting, L. L., Feb 11 2021, In: Frontiers in Oncology. 10, 599403.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Carotid Body
  • Leiomyosarcoma
  • Chemoradiotherapy
  • Liquid Biopsy
  • Blood Vessels

• Clinical assay for the early detection of colorectal cancer using mass spectrometric wheat germ agglutinin multiple reaction monitoring

  Tsai, I. J., Su, E. C. Y., Tsai, I. L. & Lin, C. Y., May 1 2021, In: Cancers. 13, 9, 2190.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Wheat Germ Agglutinins
  • Early Detection of Cancer
  • Colorectal Neoplasms
  • Biomarkers
  • Peptides

• Corrigendum to “Early versus delayed surgery after short-course radiotherapy for rectal cancer: A network meta-analysis of randomized controlled trials” [Asian J Surg S1015-9584 (19) (2019) 30824-3] (Asian Journal of Surgery (2020) 43(8) (810–818), (S1015958419308243), (10.1016/j.asjsur.2019.10.006))

  Huang, Y. J., Tai, C., Kang, Y. N. & Wei, P. L., Feb 2021, In: Asian Journal of Surgery. 44, 2, p. 526 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Network Meta-Analysis
  • Rectal Neoplasms
  • Emotions
  • Radiotherapy
  • Randomized Controlled Trials

• Corrigendum to “Effects of laparoscopic vs robotic-assisted mesorectal excision for rectal cancer: An update systematic review and meta-analysis of randomized controlled trials”. [Asian J Surg. 42 (6) 2019 Jun 657-666](S1015958418305384)(10.1016/j.asjsur.2018.11.007)

  Huang, Y. J., Kang, Y. N., Huang, Y. M., Wu, A. T., Wang, W. & Wei, P. L., Jan 2021, In: Asian Journal of Surgery. 44, 1, p. 429 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Robotics
  • Rectal Neoplasms
  • Emotions
  • Meta-Analysis
  • Systematic Reviews

• Corrigendum to “Surgical outcomes of robotic transanal minimally invasive surgery for selected rectal neoplasms: A single-hospital experience” [Asian J Surg. 43 (1) (2020 Jan) 290–296] (Asian Journal of Surgery (2020) 43(1) (290–296), (S1015958419301770), (10.1016/j.asjsur.2019.04.007))

  Huang, Y. J., Huang, Y. M., Wang, W. L., Tong, Y. S., Hsu, W. & Wei, P. L., Feb 2021, In: Asian Journal of Surgery. 44, 2, p. 525 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Transanal Endoscopic Surgery
  • Robotics
  • Rectal Neoplasms
  • Emotions

• Effect of 3-subsitution of quinolinehydroxamic acids on selectivity of histone deacetylase isoforms

  Mehndiratta, S., Chen, M. C., Chao, Y. H., Lee, C. H., Liou, J. P., Lai, M. J. & Lee, H. Y., Dec 2021, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 36, 1, p. 74-84 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Histone Deacetylases
  • A549 Cells
  • Inhibitory Concentration 50
  • 3-(5-nitrofuryl)-7-(5-nitrofurfurylidene)-3,3a,4,5,6,7-hexahydro-2H-indazole
  • Protein Isoforms

• Efficacy of cinnamon patch treatment for alleviating symptoms of overactive bladder: A double-blind, randomized, placebo-controlled trial

  Chen, L. L., Shen, Y. C., Ke, C. C., Imtiyaz, Z., Chen, H. I., Chang, C. H. & Lee, M. H., Jan 2021, In: Phytomedicine. 80, 153380.

  Research output: Contribution to journal › Article › peer-review

  • Cinnamomum zeylanicum
  • Overactive Urinary Bladder
  • Placebos
  • Randomized Controlled Trials
  • Urinary Bladder
  2 Citations (Scopus)

• EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody

  Sung, T. Y., Huang, H. L., Cheng, C. C., Chang, F. L., Wei, P. L., Cheng, Y. W., Huang, C. C., Lee, Y. C., HuangFu, W. C. & Pan, S. L., Dec 2021, In: Cell and Bioscience. 11, 1, 53.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Cell growth
  • Epidermal Growth Factor
  • Colorectal Neoplasms
  • Antibodies
  • Growth

• Enhancing Data Linkage to Break the Chain of COVID-19 Spread: The Taiwan Experience

  Lo, W-C., Wang, F-C., Lin, L-Y., Jyan, H-W., Wu, H-C., Huang, Y-L., Parng, I-M. & Chiou, H-Y., May 7 2021, In: Journal of Medical Internet Research. 23, 5, e24294.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Taiwan
  • Information Storage and Retrieval
  • Pandemics
  • Technology
  • National Health Programs

• Erratum: TIMP3 expression associates with prognosis in colorectal cancer and its novel arylsulfonamide inducer, MPT0B390, inhibits tumor growth, metastasis and angiogenesis (Theranostics (2019) 9:22 (6676-6689) DOI: 10.7150/thno.34020)

  Huang, H. L., Liu, Y. M., Sung, T. Y., Huang, T. C., Cheng, Y. W., Liou, J. P. & Pan, S. L., Jan 1 2021, In: Theranostics. 11, 5, p. 2079 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Theranostic Nanomedicine
  • Research Ethics Committees
  • Informed Consent
  • Colorectal Neoplasms
  • Neoplasm Metastasis

• Erratum: Melissa officinalis extract induces apoptosis and inhibits migration in human colorectal cancer cells (ACS Omega (2020) 5:49 (31792-31800) DOI: 10.1021/acsomega.0c04489)

  Kuo, T. T., Chang, H. Y., Chen, T. Y., Liu, B. C., Chen, H. Y., Hsiung, Y. C., Hsia, S. M., Chang, C. J. & Huang, T. C., 2021, (Accepted/In press) In: ACS Omega. 6, 8, p. 6030 1 p.

  Research output: Contribution to journal › Comment/debate › peer-review

  Open Access

  • Cell death
  • Cells
  • Apoptosis

• Genetic variants in MAPK10 modify renal cell carcinoma susceptibility and clinical outcomes

  Tsai, Y. C., Huang, C. Y., Hsueh, Y. M., Fan, Y. C., Fong, Y. C., Huang, S. P., Geng, J. H., Chen, L. C., Lu, T. L. & Bao, B. Y., Jun 15 2021, In: Life Sciences. 275, 119396.

  Research output: Contribution to journal › Article › peer-review

  • Mitogen-Activated Protein Kinases
  • Cells
  • Renal Cell Carcinoma
  • Anisomycin
  • Cell growth

• Genistein Triggers Translocation of Estrogen Receptor-Alpha in Mitochondria to Induce Expressions of ATP Synthesis-Associated Genes and Improves Energy Production and Osteoblast Maturation

  Wu, G. J., Cherng, Y. G., Chen, J. T., Chang, C. C., Liu, S. H. & Chen, R. M., 2021, (Accepted/In press) In: American Journal of Chinese Medicine.

  Research output: Contribution to journal › Article › peer-review

  • Genistein
  • Estrogen Receptor alpha
  • Osteoblasts
  • Mitochondria
  • Adenosine Triphosphate

• Glucose-regulated protein 94 mediates the proliferation and metastasis through the regulation of etv1 and mapk pathway in colorectal cancer

  Batzorig, U., Wei, P. L., Wang, W., Huang, C. Y. & Chang, Y. J., 2021, In: International Journal of Medical Sciences. 18, 11, p. 2251-2261 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • glucose-regulated proteins
  • Colorectal Neoplasms
  • Neoplasm Metastasis
  • MAP Kinase Signaling System
  • Cell Proliferation

• Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

  Klionsky, D. J., Abdel-Aziz, A. K., Abdelfatah, S., Abdellatif, M., Abdoli, A., Abel, S., Abeliovich, H., Abildgaard, M. H., Abudu, Y. P., Acevedo-Arozena, A., Adamopoulos, I. E., Adeli, K., Adolph, T. E., Adornetto, A., Aflaki, E., Agam, G., Agarwal, A., Aggarwal, B. B., Agnello, M., Agostinis, P. & 30 others, Agrewala, J. N., Agrotis, A., Aguilar, P. V., Ahmad, S. T., Ahmed, Z. M., Ahumada-Castro, U., Aits, S., Aizawa, S., Akkoc, Y., Akoumianaki, T., Akpinar, H. A., Al-Abd, A. M., Al-Akra, L., Al-Gharaibeh, A., Alaoui-Jamali, M. A., Alberti, S., Alcocer-Gómez, E., Alessandri, C., Ali, M., Alim Al-Bari, M. A., Aliwaini, S., Alizadeh, J., Almacellas, E., Almasan, A., Alonso, A., Alonso, G. D., Altan-Bonnet, N., Lin, L. T., Wu, S. Y. & Yang, P. M., 2021, (Accepted/In press) In: Autophagy.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Autophagy
  • Guidelines
  • Knowledge Bases
  • Eukaryota
  • Evaluation Studies
  35 Citations (Scopus)

• Health care needs of elderly patients with lung, liver, or colon cancer in Taiwan

  Lee, T. Y., Susanti, H. D., Hung, K. C., Yang, S. Y., Fang, H. F., Tsai, J. R., Chiou, J. F. & Chung, M. H., Dec 2021, In: BMC Palliative Care. 20, 1, 21.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Liver Neoplasms
  • Taiwan
  • Colonic Neoplasms
  • Lung Neoplasms
  • Elderly

• High-grade b-cell lymphoma (Hgbl) with myc and bcl2 and/or bcl6 rearrangements is predominantly bcl6-rearranged and bcl6-expressing in Taiwan

  Tsai, C. C., Su, Y. C., Bamodu, O. A., Chen, B. J., Tsai, W. C., Cheng, W. H., Lee, C. H., Hsieh, S. M., Liu, M. L., Fang, C. L., Lin, H. T., Chen, C. L., Yeh, C. T., Lee, W. H., Ho, C. L., Lai, S. W., Tzeng, H. E., Hsieh, Y. Y., Chang, C. L., Zheng, Y. M. & 4 others, Liu, H. W., Yen, Y., Whang-Peng, J. & Chao, T. Y., Apr 1 2021, In: Cancers. 13, 7, 1620.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • B-Cell Lymphoma
  • Taiwan
  • Non-Hodgkin's Lymphoma
  • Lymphoma
  • Lost to Follow-Up

• Identification of a dual TAOK1 and MAP4K5 inhibitor using a structure-based virtual screening approach

  Chao, M. W., Lin, T. E., HuangFu, W. C., Chang, C. D., Tu, H. J., Chen, L. C., Yen, S. C., Sung, T. Y., Huang, W. J., Yang, C. R., Pan, S. L. & Hsu, K. C., Dec 2021, In: Journal of Enzyme Inhibition and Medicinal Chemistry. 36, 1, p. 98-108 11 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Phosphotransferases
  • Cell Cycle Resting Phase
  • Enzyme Assays
  • G1 Phase
  • Neoplasms

• Interactive Effects of a Combination of the HDAC3 and HDAC9 Genes with Diabetes Mellitus on the Risk of Ischemic Stroke

  Chiou, H. Y., Bai, C. H., Lien, L. M., Hu, C. J., Jeng, J. S., Tang, S. C., Lin, H. J. & Hsieh, Y. C., Mar 2021, In: Thrombosis and Haemostasis. 121, 3

  Research output: Contribution to journal › Article › peer-review

  • Diabetes Mellitus
  • Stroke
  • Genes
  • Atherosclerosis
  • Single Nucleotide Polymorphism

• Interleukin-2 receptor alpha as a biomarker for nonalcoholic fatty liver disease diagnosis

  Kao, W. Y., Lin, Y. F., Chang, I. W., Chen, C. L., Tang, J. H., Chang, C. C., Chang, Y. J. & Wang, W., Mar 2021, In: Journal of the Chinese Medical Association. 84, 3, p. 261-266 6 p.

  Research output: Contribution to journal › Article › peer-review

  • Interleukin-2 Receptor alpha Subunit
  • Non-alcoholic Fatty Liver Disease
  • Biomarkers
  • Immunohistochemistry
  • Bariatric Surgery
  1 Citation (Scopus)

• Investigation of Selected Flavonoid Derivatives as Potent FLT3 Inhibitors for the Potential Treatment of Acute Myeloid Leukemia

  Yen, S. C., Chen, L. C., Huang, H. L., Ngo, S. T., Wu, Y. W., Lin, T. E., Sung, T. Y., Lien, S. T., Tseng, H. J., Pan, S. L., Huang, W. J. & Hsu, K. C., Jan 22 2021, In: Journal of Natural Products. 84, 1, p. 1-10 10 p.

  Research output: Contribution to journal › Article › peer-review

  • Flavonoids
  • Acute Myeloid Leukemia
  • Protein-Tyrosine Kinases
  • Derivatives
  • 6-methoxyflavone

• In vivo and in vitro evaluation of the osteogenic potential of Davallia mariesii T. Moore ex Baker

  Lin, Y. T., Peng, S. W., Imtiyaz, Z., Ho, C. W., Chiou, W. F. & Lee, M. H., Jan 10 2021, In: Journal of Ethnopharmacology. 264, 113126.

  Research output: Contribution to journal › Article › peer-review

  • Dimenhydrinate
  • In Vitro Techniques
  • Osteoblasts
  • Osteogenesis
  • Rhizome

• Involvement of microrna in solid cancer: Role and regulatory mechanisms

  Lin, Y. C., Chen, T. H., Huang, Y. M., Wei, P. L. & Lin, J. C., Apr 2021, In: Biomedicines. 9, 4, 343.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • MicroRNAs
  • Gene expression
  • Neoplasms
  • Biomarkers
  • Gene Targeting
  1 Citation (Scopus)

• Isotypes of autoantibodies against novel differential 4-hydroxy-2-nonenal-modified peptide adducts in serum is associated with rheumatoid arthritis in Taiwanese women

  Tsai, K. L., Chang, C. C., Chang, Y. S., Lu, Y. Y., Tsai, I. J., Chen, J. H., Lin, S. H., Tai, C. C., Lin, Y. F., Chang, H. W., Lin, C. Y. & Su, E. C. Y., Dec 2021, In: BMC Medical Informatics and Decision Making. 21, 1, 49.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • 4-hydroxy-2-nonenal
  • Autoantibodies
  • Rheumatoid Arthritis
  • anti-IgM
  • Peptides
  1 Citation (Scopus)

• Long-term exposure to ozone and sulfur dioxide increases the incidence of type 2 diabetes mellitus among aged 30 to 50 adult population

  Li, Y. L., Chuang, T. W., Chang, P. Y., Lin, L. Y., Su, C. T., Chien, L. N. & Chiou, H. Y., Mar 2021, In: Environmental Research. 194, 110624.

  Research output: Contribution to journal › Article › peer-review

  • Sulfur Dioxide
  • diabetes
  • Ozone
  • Medical problems
  • sulfur dioxide

• Mediation of Coping Strategies among Patients with Advanced Cancer

  Huda, N., Yun-Yen, Deli, H., Shaw, M. K., Huang, T. W. & Chang, H. J., 2021, (Accepted/In press) In: Clinical Nursing Research.

  Research output: Contribution to journal › Article › peer-review

  • Psychological Stress
  • Anxiety
  • Depression
  • Indonesia
  • Data Analysis

• Methyl gallate, gallic acid-derived compound, inhibit cell proliferation through increasing ROS production and apoptosis in hepatocellular carcinoma cells

  Huang, C. Y., Chang, Y. J., Wei, P. L., Hung, C. S. & Wang, W., Mar 2021, In: PLoS ONE. 16, 3 March, e0248521.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • methyl gallate
  • Cell proliferation
  • Gallic Acid
  • hepatoma
  • gallic acid

• Molecular Mechanisms of Chemotherapy Resistance in Head and Neck Cancers

  Kanno, Y., Chen, C. Y., Lee, H. L., Chiou, J. F. & Chen, Y. J., May 7 2021, In: Frontiers in Oncology. 11, 640392.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Head and Neck Neoplasms
  • Drug Therapy
  • Focal Adhesion Protein-Tyrosine Kinases
  • Docetaxel
  • Paclitaxel

• mTOR/EGFR/iNOS/MAP2K1/FGFR/TGFB1 Are Druggable Candidates for N-(2,4-Difluorophenyl)-2′,4′-Difluoro-4-Hydroxybiphenyl-3-Carboxamide (NSC765598), With Consequent Anticancer Implications

  Lawal, B., Lee, C-Y., Mokgautsi, N., Sumitra, M. R., Khedkar, H., Wu, A. T. H. & Huang, H-S., Mar 2021, In: Frontiers in Oncology. 11

  Research output: Contribution to journal › Article › peer-review

  • 4-phenylphenol
  • Receptor, Fibroblast Growth Factor, Type 1
  • Mitogen-Activated Protein Kinase 1
  • TOR Serine-Threonine Kinases
  • Nitric Oxide Synthase Type II
  1 Citation (Scopus)

• Nerve growth factor interacts with CHRM4 and promotes neuroendocrine differentiation of prostate cancer and castration resistance

  Chen, W. Y., Wen, Y. C., Lin, S. R., Yeh, H. L., Jiang, K. C., Chen, W. H., Lin, Y. S., Zhang, Q., Liew, P. L., Hsiao, M., Huang, J. & Liu, Y. N., Dec 2021, In: Communications Biology. 4, 1, 22.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • prostatic neoplasms
  • nerve growth factor
  • cholinergic receptors
  • castration
  • Castration

• Novel signaling pathways regulate SARS-CoV and SARS-CoV-2 infectious disease

  Cheng, L. C., Kao, T. J., Phan, N. N., Chiao, C. C., Yen, M. C., Chen, C. F., Hung, J. H., Jiang, J. Z., Sun, Z., Wang, C. Y. & Hsu, H. P., Feb 2021, In: Medicine. 100, 7, p. e24321

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Communicable Diseases
  • Coronavirus Infections
  • Gene Ontology
  1 Citation (Scopus)

• Nursing manpower forecast for cancer patients

  Chung, M. H., Hung, K. C., Chiou, J. F., Fang, H. F. & Chiu, C. H., Apr 2021, In: Computer Methods and Programs in Biomedicine. 201, 105967.

  Research output: Contribution to journal › Article › peer-review

  • Nursing
  • Workforce
  • Physicians
  • Neoplasms
  • Outpatients

• Paxillin is required for proper spinal motor axon growth into the limb

  Tsai, W-L., Chang, C-J., Wang, C-Y., Hsu, T-I., Chang, M-Y., Wu, Y-H., Chang, P-S., Lin, K-L., Chuang, J-Y., Kania, A. & Kao, T-J., Mar 16 2021, (E-pub ahead of print) In: Journal of Neuroscience.

  Research output: Contribution to journal › Article › peer-review

  • Paxillin
  • Axons
  • Extremities
  • Growth
  • Axon Guidance

• Platelet autophagic machinery involved in thrombosis through a novel linkage of AMPK-MTOR to sphingolipid metabolism

  Lee, T. Y., Lu, W. J., Changou, C. A., Hsiung, Y. C., Trang, N. T. T., Lee, C. Y., Chang, T. H., Jayakumar, T., Hsieh, C. Y., Yang, C. H., Chang, C. C., Chen, R. J., Sheu, J. R. & Lin, K. H., 2021, (Accepted/In press) In: Autophagy.

  Research output: Contribution to journal › Article › peer-review

  • Sphingolipids
  • Autophagy
  • Blood Platelets
  • Thrombosis
  • Platelet Activation

• Pragmatic recruitment of memantine as the capping group for the design of HDAC inhibitors: A preliminary attempt to unravel the enigma of glioblastoma

  Nepali, K., Hsu, T. I., Hsieh, C. M., Lo, W. L., Lai, M. J., Hsu, K. C., Lin, T. E., Chuang, J. Y. & Liou, J. P., May 5 2021, In: European Journal of Medicinal Chemistry. 217, 113338.

  Research output: Contribution to journal › Article › peer-review

  • Blood-Brain Barrier
  • Hydroxamic Acids
  • Memantine
  • Histone Deacetylase Inhibitors
  • Chemoradiotherapy

• Pretreatment Neutrophil-to-Lymphocyte Ratio Predicts Survival and Liver Toxicity in Patients With Hepatocellular Carcinoma Treated With Stereotactic Ablative Radiation Therapy

  Lo, C. H., Lee, H. L., Hsiang, C. W., Chiou, J. F., Lee, M. S., Chen, S. W., Shen, P. C., Lin, C. S., Chang, W. C., Yang, J. F., Dai, Y. H., Chen, C. Y., Chia-Hsien Cheng, J. & Huang, W. Y., Feb 1 2021, In: International Journal of Radiation Oncology Biology Physics. 109, 2, p. 474-484 11 p.

  Research output: Contribution to journal › Article › peer-review

  • neutrophils
  • lymphocytes
  • toxicity
  • Radiosurgery
  • liver

• Real-time magnetic resonance guided focused ultrasound for painful bone metastases

  Wang, W. J., Lee, H. L., Jeng, S. C., Chiou, J. F. & Huang, Y., Mar 2021, In: Journal of Visualized Experiments. 2021, 169, e60615.

  Research output: Contribution to journal › Article › peer-review

  • Magnetic resonance
  • Bone
  • Ultrasonics
  • Magnetic Resonance Spectroscopy
  • Neoplasm Metastasis

• Recent developments in epigenetic cancer therapeutics: clinical advancement and emerging trends

  Nepali, K. & Liou, J. P., Dec 2021, In: Journal of Biomedical Science. 28, 1, 27.

  Research output: Contribution to journal › Review article › peer-review

  Open Access

  • Scaffolds
  • Molecules
  • Epigenomics
  • Drug Discovery
  • Clustered Regularly Interspaced Short Palindromic Repeats
  1 Citation (Scopus)

• Ring-opening of five-membered heterocycles conjugated 4-isopropylresorcinol scaffold-based benzamides as HSP90 inhibitors suppressing tumor growth in vitro and in vivo

  Liu, Y. M., Tu, H. J., Wu, C. H., Lai, M. J., Yu, S. C., Chao, M. W., Wu, Y. W., Teng, C. M., Pan, S. L. & Liou, J. P., Jul 5 2021, In: European Journal of Medicinal Chemistry. 219, 113428.

  Research output: Contribution to journal › Article › peer-review

  • Benzamides
  • Scaffolds
  • Tumors
  • Cells
  • Inhibitory Concentration 50

• Severe acute respiratory syndrome coronavirus (Sars-cov)-2 infection induces dysregulation of immunity: In silico gene expression analysis

  Wu, Y. H., Yeh, I. J., Phan, N. N., Yen, M. C., Liu, H. L., Wang, C. Y. & Hsu, H. P., 2021, In: International Journal of Medical Sciences. 18, 5, p. 1143-1152 10 p.

  Research output: Contribution to journal › Article › peer-review

  Open Access

  • Coronavirus Infections
  • Severe Acute Respiratory Syndrome
  • Coronavirus
  • Computer Simulation
  • Immunity
  2 Citations (Scopus)