International Master/Ph.D. Program in Medicine

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2020

Activation of PERK contributes to apoptosis and G2/M arrest by microtubule disruptors in human colorectal carcinoma cells

Wu, M. S., Chien, C. C., Jargalsaikhan, G., Ilsan, N. A. & Chen, Y. C., Jan 2020, In : Cancers. 12, 1, 97.

Research output: Contribution to journalArticle

Open Access

Alda-1, an activator of ALDH2, ameliorates Achilles tendinopathy in cellular and mouse models

Liu, Y. C., Wang, H. L., Huang, Y. Z., Weng, Y. H., Chen, R. S., Tsai, W. C., Yeh, T. H., Lu, C. S., Chen, Y. L., Lin, Y. W., Chen, Y. J., Hsu, C. C., Chiu, C. H. & Chiu, C. C., May 2020, In : Biochemical Pharmacology. 175, 113919.

Research output: Contribution to journalArticle

AR ubiquitination induced by the curcumin analog suppresses growth of temozolomide-resistant glioblastoma through disrupting GPX4-Mediated redox homeostasis

Chen, T. C., Chuang, J. Y., Ko, C. Y., Kao, T. J., Yang, P. Y., Yu, C. H., Liu, M. S., Hu, S. L., Tsai, Y. T., Chan, H., Chang, W. C. & Hsu, T. I., Feb 1 2020, In : Redox Biology. 30, p. 101413 101413.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Astaxanthin protects PC12 cells against homocysteine- And glutamate-induced neurotoxicity

Chang, C. H., Chen, K. C., Liaw, K. C., Peng, C. C. & Peng, R. Y., Jan 5 2020, In : Molecules. 25, 1, 214.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Biomass and Lipid Production Potential of an Indian Marine Algal Isolate Tetraselmis striata BBRR1

Boopathy, A. B., Jayakumar, T., Chinnasamy, S., Rajaram, M. G., Mohan, N., Nagaraj, S., Rengasamy, R., Manubolu, M., Sheu, J. R. & Chang, C. C., Jan 1 2020, In : Energies. 13, 2, 341.

Research output: Contribution to journalArticle

Open Access

Circulating proteoglycan endocan mediates EGFR-driven progression of non-small cell lung cancer

Yang, Y-C., Pan, K-F., Lee, W-J., Chang, J-H., Tan, P., Gu, C-C., Chang, W-M., Yang, S-F., Hsiao, M., Hua, K-T. & Chien, M-H., Jun 19 2020, In : Cancer Research.

Research output: Contribution to journalArticle

Comparison of fractional excretion of electrolytes in patients at different stages of chronic kidney disease: A cross-sectional study

Hsiao, P. J., Liao, C. Y., Kao, Y. H., Chan, J. S., Lin, Y. F., Chuu, C. P. & Chen, J. S., Jan 1 2020, In : Medicine (United States). 99, 2, e18709.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access
1 Citation (Scopus)

Effects of ANP on pulmonary vein electrophysiology, Ca2+ homeostasis and adrenergic arrhythmogenesis via PKA

Lu, Y. Y., Cheng, C. C., Wu, H. J., Lin, Y. K., Chen, Y. C., Chen, S. A. & Chen, Y. J., Feb 1 2020, In : Clinical and Experimental Pharmacology and Physiology. 47, 2, p. 247-254 8 p.

Research output: Contribution to journalArticle

Open Access

Fractional Laser-Mediated siRNA Delivery for Mitigating Psoriasis-like Lesions via IL-6 Silencing

Lee, W. R., Lin, Y. K., Alalaiwe, A., Wang, P. W., Liu, P. Y. & Fang, J. Y., Mar 6 2020, In : Molecular Therapy - Nucleic Acids. 19, p. 240-251 12 p.

Research output: Contribution to journalArticle

Open Access

High level of physical activity reduces the risk of renal progression in hypertensive patients

Chang, P. Y., Lyu, S. Y., Lin, Y. F. & Huang, C. C., Mar 1 2020, In : International Journal of Environmental Research and Public Health. 17, 5, 1669.

Research output: Contribution to journalArticle

Open Access

Hydrolyzed chicken extract (Probeptigen®) on cognitive function in healthy middle-aged people: A randomized double-blind trial

Wu, D., Yang, C. C., Chen, K. Y., Lin, Y. C., Wu, P. J., Hsieh, P. H., Nakao, Y., Ow, M. Y. L., Hsieh, Y. C. & Hu, C. J., May 2020, In : Nutrients. 12, 5, 1362.

Research output: Contribution to journalArticle

Open Access

Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma

Yang, W-B., Hsu, C-C., Hsu, T-I., Liou, J-P., Chang, K-Y., Chen, P-Y., Liu, J-J., Yang, S-T., Wang, J-Y., Yeh, S-H., Chen, R-M., Chang, W-C. & Chuang, J-Y., Apr 24 2020, In : Neuro-Oncology.

Research output: Contribution to journalArticle

Lactotransferrin downregulation drives the metastatic progression in clear cell renal cell carcinoma

Chiu, I. J., Hsu, Y. H., Chang, J. S., Yang, J. C., Chiu, H. W. & Lin, Y. F., Apr 2020, In : Cancers. 12, 4, 847.

Research output: Contribution to journalArticle

Open Access

Limited effects of antibiotic prophylaxis in patients with Child–Pugh class A/B cirrhosis and upper gastrointestinal bleeding

Chang, T. S., Tsai, Y. H., Lin, Y. H., Chen, C. H., Lu, C. K., Huang, W. S., Yang, Y. H., Chen, W. M., Hsieh, Y. Y., Wu, Y. C., Tung, S. Y. & Huang, Y. H., Jan 1 2020, In : PLoS ONE. 15, 2, e0229101.

Research output: Contribution to journalArticle

Open Access

Macrophage migration inhibitory factor increases atrial arrhythmogenesis through CD74 signaling

Cheng, W. L., Kao, Y. H., Chen, Y. C., Lin, Y. K., Chen, S. A. & Chen, Y. J., Feb 2020, In : Translational Research. 216, p. 43-56 14 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Mammalian target of rapamycin and p70S6K mediate thrombin-induced nuclear factor-κB activation and IL-8/CXCL8 release in human lung epithelial cells

Lin, C. H., Shih, C. H., Jiang, C. P., Wen, H. C., Cheng, W. H. & Chen, B. C., Feb 5 2020, In : European Journal of Pharmacology. 868, 172879.

Research output: Contribution to journalArticle

Modulation of human platelet activation and in vivo vascular thrombosis by columbianadin: Regulation by integrin αiIbβ3 inside-out but not outside-in signals

Hou, S. M., Hsia, C. W., Tsai, C. L., Hsia, C. H., Jayakumar, T., Velusamy, M. & Sheu, J. R., May 6 2020, In : Journal of Biomedical Science. 27, 1, 60.

Research output: Contribution to journalArticle

Open Access
Open Access

Ovatodiolide suppresses oral cancer malignancy by down-regulating exosomal mir-21/STAT3/β-catenin cargo and preventing oncogenic transformation of normal gingival fibroblasts

Chen, J. H., Wu, A. T. H., Bamodu, O. A., Yadav, V. K., Chao, T. Y., Tzeng, Y. M., Mukhopadhyay, D., Hsiao, M. & Lee, J. C., Jan 2020, In : Cancers. 12, 1, 56.

Research output: Contribution to journalArticle

Open Access
Open Access

Ruthenium derivatives attenuate LPS-induced inflammatory responses and liver injury via suppressing NF-κB signaling and free radical production

Jayakumar, T., Huang, H. C., Hsia, C. W., Fong, T. H., Khamrang, T., Velusamy, M., Manubolu, M., Sheu, J. R. & Hsia, C. H., Mar 2020, In : Bioorganic Chemistry. 96, 103639.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

The establishment and application of sialoscintigraphic reference values from patients with obstructive sialadenitis

Chen, Y. C., Han, D. Y., Chang, C. C., Su, C. H., Hung, S. H. & Hsu, C. H., Apr 1 2020, In : Nuclear Medicine Communications. 41, 4, p. 308-313 6 p.

Research output: Contribution to journalArticle

Untargeted metabolomics predicts the functional outcome of ischemic stroke

Chi, N. F., Chang, T. H., Lee, C. Y., Wu, Y. W., Shen, T. A., Chan, L., Chen, Y. R., Chiou, H. Y., Hsu, C. Y. & Hu, C. J., Jan 1 2020, (Accepted/In press) In : Journal of the Formosan Medical Association.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
2019

A case-control study of the association between sialolithiasis and osteoporosis

Hung, S. H., Xirasagar, S., Cheng, Y. F. & Lin, H. C., May 2019, In : Clinical Otolaryngology. 44, 3, p. 343-348 6 p.

Research output: Contribution to journalArticle

A critical period for the development of schizophrenia-like pathology by aberrant postnatal neurogenesis

Sheu, J. R., Hsieh, C. Y., Jayakumar, T., Tseng, M. F., Lee, H. N., Huang, S. W., Manubolu, M. & Yang, C. H., Jan 1 2019, In : Frontiers in Neuroscience. 13, JUN, 635.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
1 Citation (Scopus)

Acupuncture treatment and the risk of urinary tract infection in stroke patients: a nationwide matched cohort study

Yang, J. L., Chen, T. L., Yeh, C. C., Hu, C. J., Liao, C. C., Lane, H. L. & Shih, C. C., Jan 1 2019, In : Acupuncture in Medicine.

Research output: Contribution to journalArticle

Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis

Jan, Y. H., Lai, T. C., Yang, C. J., Lin, Y. F., Huang, M. S. & Hsiao, M., Jan 29 2019, In : Journal of Hematology and Oncology. 12, 1, 12.

Research output: Contribution to journalArticle

5 Citations (Scopus)

A double-virally-inactivated (Intercept–solvent/detergent) human platelet lysate for in vitro expansion of human mesenchymal stromal cells

Barro, L., Su, Y. T., Nebie, O., Wu, Y. W., Huang, Y. H., Koh, M. B. C., Knutson, F. & Burnouf, T., Jun 2019, In : Transfusion. 59, 6, p. 2061-2073 13 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Adverse stroke outcomes among patients with bipolar disorder

Chen, P. H., Kao, Y. W., Shia, B. C., Lin, H. C. & Kang, J. H., Mar 1 2019, In : PLoS One. 14, 3, p. e0213072 e0213072.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Angiotensin-converting enzyme inhibitors or angiotensin receptor blocker monotherapy retard deterioration of renal function in Taiwanese chronic kidney disease population

Zheng, C. M., Wang, J. Y., Chen, T. T., Wu, Y. C., Wu, Y. L., Lin, H. T., Chiu, S. P., Chang, T. J., Zheng, J. Q., Chu, N. F., Lin, Y. M., Su, S. L., Lu, K. C., Chen, J. S., Sung, F. C., Lee, C. T., Yang, Y., Hwang, S. J., Wang, M. C., Hsu, Y. H. & 4 others, Chiou, H. Y., Kao, S., Wu, M. Y. & Lin, Y. F., Dec 1 2019, In : Scientific Reports. 9, 1, 2694.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access
1 Citation (Scopus)

An Open-Label, Multicenter, Phase I, Dose Escalation Study with Phase II Expansion Cohort to Determine the Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Intravenous TKM-080301 in Subjects with Advanced Hepatocellular Carcinoma

El Dika, I., Lim, H. Y., Yong, W. P., Lin, C. C., Yoon, J. H., Modiano, M., Freilich, B., Choi, H. J., Chao, T. Y., Kelley, R. K., Brown, J., Knox, J., Ryoo, B. Y., Yau, T. & Abou-Alfa, G. K., Jan 1 2019, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Open Access
10 Citations (Scopus)

Antrocin, a bioactive component from Antrodia cinnamomea, suppresses breast carcinogenesis and stemness via downregulation of β-catenin/Notch1/Akt signaling

Chen, J. H., T.H Wu, A., T.W Tzeng, D., Huang, C. C., Tzeng, Y. M. & Chao, T. Y., Jan 1 2019, In : Phytomedicine. 52, p. 70-78 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)