Graduate Institute of Pharmacognosy

Projects

Projects per year 2010 2011 2012 2013 2014 2015 2017 2020 2021 2023

• 7 Active
• 144 Finished

Projects per year

Search results

• Exploiting Acridine Scaffold to Develop Novel Anticancer Agents Based on a Dual Target Strategy

  Huang, W.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone 100%
  • Topoisomerase Inhibitor 34%
  • Structure-Activity Relationship 26%
  • Antineoplastic Agent 18%
  • Camptothecin 13%

• Evaluations of Apolipoprotein E on the Pathological Role in Lung Cancer and the Application in Early Prediction of Clinical Outcome

  Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lung Neoplasms 100%
  • Apolipoproteins E 98%
  • Hyperlipidemias 84%
  • Growth 33%
  • Formal Social Control 25%

• Evaluation of the Effects of Plant Trypsin Inhibitors on Lipoprotein Binding and Metabolism

  Hou, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • trypsin inhibitors 100%
  • low density lipoprotein 79%
  • low density lipoprotein receptors 54%
  • hyperlipidemia 49%
  • subtilisin 35%

• Establishment of Screening Platform by Novel Bio-Markers of Clinical Osteoporosis and Development of Taiwanese Native Plants in Bone Remodeling: in Vivo and in Vitro Study(3/3)

  Lee, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Establishment of Screening Platform by Novel Bio-Markers of Clinical Osteoporosis and Development of Taiwanese Native Plants in Bone Remodeling: in Vivo and in Vitro Study

  Lee, M.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Establishment of Screening Platform by Novel Bio-Markers of Clinical Osteoporosis and Development of Taiwanese Native Plants in Bone Remodeling: in Vivo and in Vitro Study

  Lee, M.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Establish a E-learning platform for Fundamental of Chinese Medicine

  Liang, W., Wang, C. & Sheu, S.

  2/10/11 → 12/31/11

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • medicine 100%
  • electronic learning 49%
  • learning 17%
  • drug interactions 13%
  • therapeutics 7%

• Establish a E-learning platform for Clinical Application of Chinese Medicine

  Wang, C.

  1/23/13 → 12/15/13

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • electronic learning 100%
  • medicine 67%
  • learning 34%
  • therapeutics 14%
  • methodology 5%

• Effects of Functional Peptides Derived from Yam Dioscorin on Anti-aging Activities and Related Mechanisms

  Hou, W.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Peptide 100%
  • Antioxidant Agent 73%
  • Methylglyoxal 51%
  • Galactose 39%
  • Oxidative Stress 38%

• Effects of Curcumin and Its 25 Kinds of Structural Analogs on Antiproliferation, Antimetastasis, Solubility Improvements, and Related Mechanism Investigations

  Hou, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Curcumin 100%
  • Antimetastatic 16%
  • Cell Viability 10%
  • Intraperitoneal 6%
  • Blood Pressure 6%

• Drugs for Metabolic Syndrome---Structural Optimization of Hypoglycemic nstpbp 168 Derivatives and HSU-STD Lead Compounds

  Hsu, F.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Antidiabetic Agent 100%
  • Total Synthesis 71%
  • Modification 45%
  • Drug 43%
  • Compound Derivative 36%

• Discovery of Multitarget Agents That Target Alzheimer'S Disease

  Huang, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of the Fully Humanized Bispecific Antibody to One-Step Expand and Arm T Cells for Selective Tumor Therapy(3/3)

  Chuang, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • T-Lymphocytes 100%
  • Bispecific Antibodies 62%
  • Muromonab-CD3 39%
  • Blood Cells 18%
  • Cell- and Tissue-Based Therapy 13%

• Development of the Fully Humanized Bispecific Antibody to One-Step Expand and Arm T Cells for Selective Tumor Therapy

  Chuang, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • T-Lymphocytes 100%
  • Bispecific Antibodies 62%
  • Muromonab-CD3 39%
  • Blood Cells 18%
  • Cell- and Tissue-Based Therapy 13%

• Development of the Fully Humanized Bispecific Antibody to One-Step Expand and Arm T Cells for Selective Tumor Therapy

  Chuang, K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • T-Lymphocytes 100%
  • Bispecific Antibodies 62%
  • Muromonab-CD3 39%
  • Blood Cells 18%
  • Cell- and Tissue-Based Therapy 13%

• Development of Targeted Cancer Agents Using a Naturally Occurring Scaffold and Knowledge-Based Design

  Huang, W.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone 100%
  • Antitumor 25%
  • Antiproliferative 18%
  • Antineoplastic Agent 16%
  • Osthole 16%

• Development of Prediction System of Cell-Free Methylated Dna Markers for Tracking Treatment Response and Recurrence of Breast Cancer Patients Following Treatment

  Lin, R.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Novel HDAC Inhibitors from Natural Products and Studies on Their Biological Activities

  Huang, W.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hydroxylysine 100%
  • Histone 34%
  • Acetylation 21%
  • Modification 17%
  • Occurrence in Nature 17%

• Development of Novel Dna Methyltransferases Inhibitors for Breast Cancer Treatment

  Lin, R. & Huang, W.

  1/1/11 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • mithramycin A 100%
  • mithramycin SK 42%
  • Tumor Suppressor Genes 37%
  • Neoplasms 32%
  • CpG Islands 22%

• Development of Dna Methyltransferases Inhibitors from Natural Products for Target Therapy of Lung Cancer

  Lin, R.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • mithramycin A 100%
  • Tumor Suppressor Genes 56%
  • DNA Methylation 28%
  • Lung Neoplasms 22%
  • Tissue Inhibitor of Metalloproteinase-3 21%

• Development of Breast Cancer Early Detection and Post-Treatment Smart Healthcare Tracking Platform

  Lin, R.

  6/1/19 → 5/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Anti-Α9nachr/Anti-Polyethylene Glycol Bispecific Antibody to Enhance the Therapeutic Efficacy of Nano-Drugs against Breast Cancer( III )Development of Anti-Α9nachr/Anti-Polyethylene Glycol Bispecific Antibody to Enhance the Therapeutic Efficacy of Nano-Drugs against Breast Cancer( III )

  Chuang, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Anti-Α9nachr/Anti-Polyethylene Glycol Bispecific Antibody to Enhance the Therapeutic Efficacy of Nano-Drugs against Breast Cancer(II)(2/3)

  Chuang, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Anti-Α9nachr/Anti-Polyethylene Glycol Bispecific Antibody to Enhance the Therapeutic Efficacy of Nano-Drugs against Breast Cancer( I )

  Chuang, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Anti-Α9nachr/Anti-Cd3 Bispecific Antibody to One-Step Construct an Armed T Cell Immunotherapy for Efficiently Eliminating Breast Tumor( III )

  Chuang, K.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Antagonistic Bace-2 Antibodies to Improve Type 2 Diabetes by Inducing Pancreatic Beta-Cells Proliferation( II )

  Chuang, K.

  8/1/22 → 7/31/23

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of an Innovative Bispecific Engager Simultaneously Binding Pd-L1 and Cd28 to Reverse Immunosuppressive Tumor Microenvironment for Enhancing Anti-Cancer Efficacy of T Cell-Based Therapies

  Chuang, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development and utilization of indigenous Taiwanese herbal medicine - Uncaria hirsuta Haviland

  Lee, M., Hou, W. & Lin, C.

  5/5/11 → 12/31/11

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Neuroprotective 100%
  • Heat 57%
  • Convulsion 57%
  • Blood Pressure 49%
  • Liquid 42%

• Design and Preclinical Translation Study of Mixed-Bispecific/Trispecific Antibody for Enhancing Therapeutic Effectiveness of Anticancer Drug-Loaded Pegylated Nanocarriers by Simultaneously Targeting to Tumor Cells and Cancer/Tumor Associated Fibrobla (I)

  Sheu, M., Chuang, K. & Ho, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Nanocarrier 100%
  • Antigen 77%
  • Tumor Marker 61%
  • Modification 51%
  • Liposome 42%

• Chinese prescriptions for external application in acne(2-2)

  Wang, C.

  12/2/11 → 11/20/12

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Acne Vulgaris 100%
  • Evidence-Based Medicine 33%
  • Lipase 16%
  • Chinese Traditional Medicine 15%
  • Prescriptions 12%

• Chinese prescriptions for external application in acne(2-1)

  Wang, C.

  11/15/10 → 11/20/11

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Acne Vulgaris 100%
  • Medicine 80%
  • Systematic Reviews 65%
  • Clinical Medicine 26%
  • Herbal Medicine 24%

• Characterizationof Platelet-Rich Fibrin Releasing Growth Factors and Its Application on Regeneration of Nerve Injury during Radical Prostatectomy

  Ho, H.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibrin 100%
  • prostatic neoplasms 58%
  • nerve regeneration 51%
  • growth factors 40%
  • adhesives 38%

• Characterizationof Platelet-Rich Fibrin Releasing Growth Factors and Its Application on Regeneration of Nerve Injury during Radical Prostatectomy

  Ho, H. & Chiang, H.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • fibrin 100%
  • prostatic neoplasms 58%
  • nerve regeneration 51%
  • growth factors 40%
  • adhesives 38%

• Application of Clinical Anti-Arthralgia Formulas of Traditional Chinese Medicine to Arthritis

  Wang, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • medicine 100%
  • health insurance 57%
  • Taiwan 46%
  • basic research 30%
  • literature 23%

• Application of Clinical Anti-Arthralgia Formulas of Traditional Chinese Medicine to Arthritis

  Wang, C.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • medicine 100%
  • health insurance 57%
  • Taiwan 46%
  • basic research 30%
  • literature 23%

• Application of clinical anti-arthralgia formulas of traditional Chinese medicine to arthritis

  Wang, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • medicine 100%
  • health insurance 57%
  • Taiwan 46%
  • basic research 30%
  • literature 23%

• Anti-Arthritis Constituents of Punica granatum Linne

  Wang, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • arthritis 100%
  • pomegranates 86%
  • alternative medicine 25%
  • Punica granatum 23%
  • standard operating procedures 14%

• Anti-Arthritis Constituents of Punica granatum Linne

  Wang, C.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • arthritis 100%
  • pomegranates 86%
  • alternative medicine 25%
  • Punica granatum 23%
  • standard operating procedures 14%

• Adapting novel chemical strategies and exploitation biosynthetic pathways for the synthesis of triterpene saponins for pharmacologic studies

  Hsieh, Y.

  1/12/21 → 12/31/23

  Project: D - Other Project

• A Clinical Correlation Study of DNA Methyltransferases Alterations in Breast Cancer and Evaluation of DNA Methyltransferases as a Therapeutic Target in Cell and Animal Models

  Lin, R.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Tumor Suppressor Genes 95%
  • DNA (Cytosine-5-)-Methyltransferase 1 67%
  • Methyltransferases 40%
  • DNA Methylation 35%

• A Clinical Correlation Study of Dna Methyltransferases Alterations in Breast Cancer and Evaluation of Dna Methyltransferases as a Therapeutic Target in Cell and Animal Models

  Lin, R.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Tumor Suppressor Genes 95%
  • DNA (Cytosine-5-)-Methyltransferase 1 67%
  • Methyltransferases 40%
  • DNA Methylation 35%

• A Clinical Correlation study of DNA Methyltransferases Alterations in Breast Cancer and Evaluation of DNA Methyltransferases as a Therapeutic Target in Cell and Animal Models

  Lin, R.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Breast Neoplasms 100%
  • Tumor Suppressor Genes 95%
  • DNA (Cytosine-5-)-Methyltransferase 1 67%
  • Methyltransferases 40%
  • DNA Methylation 35%

• A blood circulation-mimicking microfluidic thrombosis device to assess novel thrombin-responsive, anticoagulant sulfopeptide carriers under fluid shear

  Hsieh, Y.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 2014馬祖特用植物之開發應用

  Lee, M.

  7/25/14 → 7/30/15

  Project: A - Government Institution › f - Other (Funded by Government)

• 108年度毛豆機能性產品動物功效驗證

  Chuang, K.

  3/29/19 → 12/29/19

  Project: A - Government Institution › e - Council of Agriculture

• 106年度「大豆(毛豆)機能性產品動物功效驗證」研究委辦勞務採購

  Chuang, K.

  2/22/17 → 12/25/17

  Project: A - Government Institution › e - Council of Agriculture

• 106年度「中西藥交互作用實證資料探討分析」

  Lee, C.

  2/21/17 → 12/15/17

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 105馬祖地區原生植物藥性分析工作案

  Lee, M.

  10/11/16 → 10/10/17

  Project: A - Government Institution › f - Other (Funded by Government)

• 105年度大豆(毛豆)產品動物功效驗證之研究委辦計畫

  Chuang, K.

  2/1/16 → 12/15/16

  Project: A - Government Institution › e - Council of Agriculture

• 103年度「國際中醫藥產業發展趨勢探討與對策研析」

  Wu, C., Lee, M. & Chen, M.

  12/10/14 → 10/31/15

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Industry 100%
  • Communication 41%
  • Drug 24%
  • Time 16%