Graduate Institute of Pharmacognosy

Projects

Projects per year 2010 2011 2012 2013 2014 2015 2017 2020 2023

• 5 Active
• 137 Finished

Projects per year

Search results

• Active

  結構優化苯丙炔醯胺基礎之蛋白質雙硫鍵異構酶抑制劑以作為具潛力之抗多形性神經膠質母細胞瘤試劑(1/3)

  Huang, W.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-開發抗α9尼古丁受體/抗CD3雙功能抗體以一步驟建構可高效標靶毒殺乳癌腫瘤之武裝型T細胞免疫療法(2/3)

  Chuang, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以體內外模式進行臺灣藥草及其成分於骨質重塑作用之探討(1/3)

  Lee, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發可刺激胰島beta細胞增生之拮抗型BACE-2抗體以改善第二型糖尿病(1/3)

  Chuang, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Adapting novel chemical strategies and exploitation biosynthetic pathways for the synthesis of triterpene saponins for pharmacologic studies

  Hsieh, Y.

  1/12/21 → 12/31/23

  Project: D - Other Project

• Finished

  探索治療神經纖維瘤之抗發炎天然物

  Lai, K.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 利用內生性報告基因轉殖鼠以開發第一型糖尿病之治療藥物及其應用策略

  Chuang, K.

  1/1/21 → 12/31/21

  Project: A - Government Institution › a - National Health Research Institutes

• 中藥治療發炎疾病的化學與藥理圖譜研究

  Lai, K.

  1/1/21 → 10/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探索治療神經纖維瘤之抗發炎天然物

  Lai, K.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• A blood circulation-mimicking microfluidic thrombosis device to assess novel thrombin-responsive, anticoagulant sulfopeptide carriers under fluid shear

  Hsieh, Y.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 新聘教師研究補助

  Lai, K.

  12/15/20 → 12/14/21

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 產學合作計畫－開發千根草於調控骨頭再塑產品之應用

  Lee, M.

  11/1/20 → 10/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探索衰老新穎性標的與神經退化性疾病相互作用並以衰老作為開發神經保護潛力藥物之新策略

  Lee, M.

  8/1/20 → 7/31/21

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 乳癌細胞α9尼古丁受體作為新穎靶向RNA奈米藥物與T細胞療法之臨床轉譯研究-開發抗α9尼古丁受體/抗CD3雙功能抗體以一步驟建構可高效標靶毒殺乳癌腫瘤之武裝型T細胞免疫療法(1/3)

  Chuang, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 桑黃天然物hispolon及其結構衍生物延緩老化與神經退化疾病的研究:從體外試驗到體內動物模式(3/3)

  Hou, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發蛋白質雙硫鍵異構酶抑制劑作為抗多形性神經膠質母細胞瘤藥物

  Huang, W.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發新型EGFR專一性之武裝型T細胞(Anti-EGFR BsAb Armed T cell)以應用於三陰性乳癌之治療

  Chuang, K.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 開發拮抗型BACE-2抗體逆轉第二型糖尿病胰島凋亡之病程

  Chuang, K.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 芸香科中草藥於抑制酒糟性皮膚炎指標酵素及相關活性與成分分析之探討

  Lee, M.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎小分子抗多發性骨髓瘤藥物機轉研究

  Huang, W.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 類薑黃素誘導人類大腸癌細胞株計畫性死亡探討

  Hou, W.

  3/1/20 → 2/28/21

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• 利用內生性報告基因轉殖鼠以開發第一型糖尿病之治療藥物及其應用策略

  Chuang, K.

  1/1/20 → 12/31/20

  Project: A - Government Institution › a - National Health Research Institutes

• Studies of Hispolon and Its Structural Analogues on Delaying Aging Process and Neurodegenerative Disorders in Vitro and in Vivo(2/3)

  Hou, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Establishment of Screening Platform by Novel Bio-Markers of Clinical Osteoporosis and Development of Taiwanese Native Plants in Bone Remodeling: in Vivo and in Vitro Study(3/3)

  Lee, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of an Innovative Bispecific Engager Simultaneously Binding Pd-L1 and Cd28 to Reverse Immunosuppressive Tumor Microenvironment for Enhancing Anti-Cancer Efficacy of T Cell-Based Therapies

  Chuang, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Prediction System of Cell-Free Methylated Dna Markers for Tracking Treatment Response and Recurrence of Breast Cancer Patients Following Treatment

  Lin, R.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Anti-Α9nachr/Anti-Polyethylene Glycol Bispecific Antibody to Enhance the Therapeutic Efficacy of Nano-Drugs against Breast Cancer( III )Development of Anti-Α9nachr/Anti-Polyethylene Glycol Bispecific Antibody to Enhance the Therapeutic Efficacy of Nano-Drugs against Breast Cancer( III )

  Chuang, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Discovery of Multitarget Agents That Target Alzheimer'S Disease

  Huang, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Breast Cancer Early Detection and Post-Treatment Smart Healthcare Tracking Platform

  Lin, R.

  6/1/19 → 5/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 108年度毛豆機能性產品動物功效驗證

  Chuang, K.

  3/29/19 → 12/29/19

  Project: A - Government Institution › e - Council of Agriculture

• 白藜蘆醇二聚體化合物抑制脂肪堆積的活性評估

  Hou, W.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• Development of the Fully Humanized Bispecific Antibody to One-Step Expand and Arm T Cells for Selective Tumor Therapy(3/3)

  Chuang, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • T-Lymphocytes 100%
  • Muromonab-CD3 39%
  • Bispecific Antibodies 20%
  • Blood Cells 18%
  • Cell- and Tissue-Based Therapy 13%

• Exploiting Acridine Scaffold to Develop Novel Anticancer Agents Based on a Dual Target Strategy

  Huang, W.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone 100%
  • Topoisomerase Inhibitor 34%
  • Structure-Activity Relationship 26%
  • Antineoplastic Agent 18%
  • Camptothecin 13%

• Establishment of Screening Platform by Novel Bio-Markers of Clinical Osteoporosis and Development of Taiwanese Native Plants in Bone Remodeling: in Vivo and in Vitro Study

  Lee, M.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Anti-Α9nachr/Anti-Polyethylene Glycol Bispecific Antibody to Enhance the Therapeutic Efficacy of Nano-Drugs against Breast Cancer(II)(2/3)

  Chuang, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies of Hispolon and Its Structural Analogues on Delaying Aging Process and Neurodegenerative Disorders in Vitro and in Vivo

  Hou, W.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 「大豆(毛豆)機能性產品動物功效驗證」委辦勞務採購案

  Chuang, K.

  4/13/18 → 12/15/18

  Project: A - Government Institution › e - Council of Agriculture

• 探討小葉葡萄抑制二肽基胜肽酶-4活性與改善葡萄糖不耐受性的研究

  Hou, W.

  3/1/18 → 2/28/19

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• Study of Novel Genes Regulated by Aberrant Dna Methylation and Application in Colon Cancer Treatment

  Lin, R.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Neoplasm Genes 100%
  • Methylation 91%
  • Taiwan 82%
  • DNA Methylation 72%
  • Colonic Neoplasms 66%

• Development of the Fully Humanized Bispecific Antibody to One-Step Expand and Arm T Cells for Selective Tumor Therapy

  Chuang, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • T-Lymphocytes 100%
  • Muromonab-CD3 39%
  • Bispecific Antibodies 20%
  • Blood Cells 18%
  • Cell- and Tissue-Based Therapy 13%

• Development of Anti-Α9nachr/Anti-Polyethylene Glycol Bispecific Antibody to Enhance the Therapeutic Efficacy of Nano-Drugs against Breast Cancer( I )

  Chuang, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Exploiting Acridine Scaffold to Develop Novel Anticancer Agents Based on a Dual Target Strategy

  Huang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone 100%
  • Topoisomerase Inhibitor 34%
  • Structure-Activity Relationship 26%
  • Antineoplastic Agent 18%
  • Camptothecin 13%

• 以小分子化合物開發新穎且具選擇性塗藥用於血管支架(先期補助)

  Huang, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › f - Other (Funded by Government)

• Evaluation of the Effects of Plant Trypsin Inhibitors on Lipoprotein Binding and Metabolism

  Hou, W.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • trypsin inhibitors 100%
  • low density lipoprotein 79%
  • low density lipoprotein receptors 54%
  • hyperlipidemia 49%
  • subtilisin 35%

• Establishment of Screening Platform by Novel Bio-Markers of Clinical Osteoporosis and Development of Taiwanese Native Plants in Bone Remodeling: in Vivo and in Vitro Study

  Lee, M.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 臺灣特色茶品異溫萃取物之活性成分分析及對於骨質新生作用之探討

  Lee, M.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 表現膜抗體報告基因於第一型糖尿病鼠之胰島細胞以非侵犯性造影自體免疫型糖尿病之病程

  Chuang, K.

  7/1/17 → 2/28/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討山藥儲藏性蛋白質胃蛋白酶水解之區分物及模擬水解合成之胜肽抑制二肽基胜肽酶-4活性與改善葡萄糖不耐性的可行性評估

  Hou, W.

  3/1/17 → 2/28/18

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• 106年度「大豆(毛豆)機能性產品動物功效驗證」研究委辦勞務採購

  Chuang, K.

  2/22/17 → 12/25/17

  Project: A - Government Institution › e - Council of Agriculture

• 106年度「中西藥交互作用實證資料探討分析」

  Lee, C.

  2/21/17 → 12/15/17

  Project: A - Government Institution › c - Ministry of Health and Welfare