Graduate Institute of Clinical Medicine

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output

2020

A multicenter, phase I/II trial of biweekly S-1, leucovorin, oxaliplatin and gemcitabine in metastatic pancreatic adenocarcinoma–TCOG T1211 study

Chiang, N. J., Tsai, K. K., Hsiao, C. F., Yang, S. H., Hsiao, H. H., Shen, W. C., Hsu, C., Lin, Y. L., Chen, J. S., Shan, Y. S. & Chen, L. T., Jan 2020, In : European Journal of Cancer. 124, p. 123-130 8 p.

Research output: Contribution to journalArticle

Astaxanthin protects PC12 cells against homocysteine- And glutamate-induced neurotoxicity

Chang, C. H., Chen, K. C., Liaw, K. C., Peng, C. C. & Peng, R. Y., Jan 5 2020, In : Molecules. 25, 1, 214.

Research output: Contribution to journalArticle

Open Access

CD44-associated radioresistance of glioblastoma in irradiated brain areas with optimal tumor coverage

Liu, W. H., Lin, J. C., Chou, Y. C., Li, M. H. & Tsai, J. T., Jan 1 2020, In : Cancer Medicine. 9, 1, p. 350-360 11 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Comparison of fractional excretion of electrolytes in patients at different stages of chronic kidney disease: A cross-sectional study

Hsiao, P. J., Liao, C. Y., Kao, Y. H., Chan, J. S., Lin, Y. F., Chuu, C. P. & Chen, J. S., Jan 1 2020, In : Medicine (United States). 99, 2, e18709.

Research output: Contribution to journalArticle

Open Access

Dishevelled 1-Regulated Superpotent Cancer Stem Cells Mediate Wnt Heterogeneity and Tumor Progression in Hepatocellular Carcinoma

Liao, W. Y., Hsu, C. C., Chan, T. S., Yen, C. J., Chen, W. Y., Pan, H. W. & Tsai, K. K., Mar 10 2020, In : Stem Cell Reports. 14, 3, p. 462-477 16 p.

Research output: Contribution to journalArticle

Open Access

Effects of ANP on pulmonary vein electrophysiology, Ca2+ homeostasis and adrenergic arrhythmogenesis via PKA

Lu, Y. Y., Cheng, C. C., Wu, H. J., Lin, Y. K., Chen, Y. C., Chen, S. A. & Chen, Y. J., Feb 1 2020, In : Clinical and Experimental Pharmacology and Physiology. 47, 2, p. 247-254 8 p.

Research output: Contribution to journalArticle

Erratum: Author Correction: Relationship between body mass index and renal function deterioration among the Taiwanese chronic kidney disease population (Scientific reports (2018) 8 1 (6908))

Chang, T. J., Zheng, C. M., Wu, M. Y., Chen, T. T., Wu, Y. C., Wu, Y. L., Lin, H. T., Zheng, J. Q., Chu, N. F., Lin, Y. M., Su, S. L., Lu, K. C., Chen, J. S., Sung, F. C., Lee, C. T., Yang, Y., Hwang, S. J., Wang, M. C., Hsu, Y. H., Chiou, H. Y. & 2 others, Kao, S. & Lin, Y. F., Feb 13 2020, In : Scientific Reports. 10, 1, 1 p.

Research output: Contribution to journalComment/debate

Open Access

High level of physical activity reduces the risk of renal progression in hypertensive patients

Chang, P. Y., Lyu, S. Y., Lin, Y. F. & Huang, C. C., Mar 1 2020, In : International Journal of Environmental Research and Public Health. 17, 5, 1669.

Research output: Contribution to journalArticle

Open Access

Histone 2A family member j drives mesenchymal transition and temozolomide resistance in glioblastoma multiforme

Lee, H. H., Lin, C. H., Lin, H. Y., Kuei, C. H., Zheng, J. Q., Wang, Y. H., Lu, L. S., Lee, F. P., Hu, C. J., Wu, D. & Lin, Y. F., Jan 2020, In : Cancers. 12, 1, 98.

Research output: Contribution to journalArticle

Open Access

In vitro and in vivo evaluation of the neuroprotective activity of Uncaria hirsuta Haviland

Lin, C. M., Lin, Y. T., Lee, T. L., Imtiyaz, Z., Hou, W. C. & Lee, M. H., Jan 2020, In : Journal of Food and Drug Analysis. 28, 1, p. 147-158 12 p.

Research output: Contribution to journalArticle

Open Access

Killer cell immunoglobulin-like receptors (KIR) and human leukocyte antigen-C (HLA-C) allorecognition patterns in women with endometriosis

Chou, Y. C., Chen, C. H., Chen, M. J., Chang, C. W., Chen, P. H., Yu, M. H., Chen, Y. J., Tsai, E. M., Yang, P. S., Lin, S. Y. & Tzeng, C. R., Dec 1 2020, In : Scientific Reports. 10, 1, 4897.

Research output: Contribution to journalArticle

Open Access

Macrophage migration inhibitory factor increases atrial arrhythmogenesis through CD74 signaling

Cheng, W. L., Kao, Y. H., Chen, Y. C., Lin, Y. K., Chen, S. A. & Chen, Y. J., Feb 2020, In : Translational Research. 216, p. 43-56 14 p.

Research output: Contribution to journalArticle

Optimal measuring timing of cystatin C for early detection of contrast-induced acute kidney injury: A systematic review and meta-analysis

Chen, C. T., Chang, L. Y., Chuang, C. W., Wang, S. C., Kao, M. C., Tzeng, I. S., Kuo, K. L., Wu, C. C., Tsai, P. S. & Huang, C. J., Jan 2020, In : Toxicology Letters. 318, p. 65-73 9 p.

Research output: Contribution to journalArticle

Ovatodiolide suppresses oral cancer malignancy by down-regulating exosomal mir-21/STAT3/β-catenin cargo and preventing oncogenic transformation of normal gingival fibroblasts

Chen, J. H., Wu, A. T. H., Bamodu, O. A., Yadav, V. K., Chao, T. Y., Tzeng, Y. M., Mukhopadhyay, D., Hsiao, M. & Lee, J. C., Jan 2020, In : Cancers. 12, 1, 56.

Research output: Contribution to journalArticle

Open Access

Potent impact of plastic nanomaterials and micromaterials on the food chain and human health

Wang, Y. L., Lee, Y. H., Chiu, I. J., Lin, Y. F. & Chiu, H. W., Mar 1 2020, In : International Journal of Molecular Sciences. 21, 5, 1727.

Research output: Contribution to journalReview article

Open Access

Relationship Between Diurnal Cortisol Profile and Sleep Quality in Patients With Hepatocellular Carcinoma

Huang, T. W., Cheung, D. S. T., Xu, X., Loh, E. W., Lai, J. H., Su, W. W., Wu, S. S. & Lin, C. C., Jan 1 2020, In : Biological Research for Nursing. 22, 1, p. 139-147 9 p.

Research output: Contribution to journalArticle

The influence of atrial fibrillation on the mortality of incident ESRD patients undergoing maintenance hemodialysis

Hsieh, H. L., Hsu, S. C., Cheng, H. S., Chen, C. Y., Huang, W., Sue1, Y. M., Lin, F. Y., Shih, C. M., Chen, J., Lin, S. J., Huang, P. H. & Liu, C., Jan 1 2020, In : PLoS ONE. 15, 1, e0228405.

Research output: Contribution to journalArticle

Open Access
2019

A bioinspired hyperthermic macrophage-based polypyrrole-polyethylenimine (Ppy-PEI) nanocomplex carrier to prevent and disrupt thrombotic fibrin clots

Burnouf, T., Chen, C. H., Tan, S. J., Tseng, C. L., Lu, K. Y., Chang, L. H., Nyambat, B., Huang, S. C., Jheng, P. R., Aditya, R. N., Mi, F. L. & Chuang, E. Y., Sep 15 2019, In : Acta Biomaterialia. 96, p. 468-479 12 p.

Research output: Contribution to journalArticle

Adenylate kinase 4 modulates oxidative stress and stabilizes HIF-1α to drive lung adenocarcinoma metastasis

Jan, Y. H., Lai, T. C., Yang, C. J., Lin, Y. F., Huang, M. S. & Hsiao, M., Jan 29 2019, In : Journal of Hematology and Oncology. 12, 1, 12.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Adverse stroke outcomes among patients with bipolar disorder

Chen, P. H., Kao, Y. W., Shia, B. C., Lin, H. C. & Kang, J. H., Mar 1 2019, In : PLoS One. 14, 3, p. e0213072 e0213072.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)
Open Access

Alteration of mesenchymal stem cells polarity by laminar shear stimulation promoting β-catenin nuclear localization

Chen, W-T., Hsu, W-T., Yen, M-H., Changou, C. A., Han, C-L., Chen, Y-J., Cheng, J-Y., Chang, T-H., Lee, O. K-S. & Ho, J. H-C., Jan 1 2019, In : Biomaterials. 190-191, p. 1-10 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

A new histone deacetylase inhibitor enhances radiation sensitivity through the induction of misfolded protein aggregation and autophagy in triple-negative breast cancer

Chiu, H. W., Yeh, Y. L., Ho, S. Y., Wu, Y. H., Wang, B. J., Huang, W. J., Ho, Y. S., Wang, Y. J., Chen, L. C. & Tu, S. H., Nov 1 2019, In : Cancers. 11, 11, 1703.

Research output: Contribution to journalArticle

Open Access

Angiotensin-converting enzyme inhibitors or angiotensin receptor blocker monotherapy retard deterioration of renal function in Taiwanese chronic kidney disease population

Zheng, C. M., Wang, J. Y., Chen, T. T., Wu, Y. C., Wu, Y. L., Lin, H. T., Chiu, S. P., Chang, T. J., Zheng, J. Q., Chu, N. F., Lin, Y. M., Su, S. L., Lu, K. C., Chen, J. S., Sung, F. C., Lee, C. T., Yang, Y., Hwang, S. J., Wang, M. C., Hsu, Y. H. & 4 others, Chiou, H. Y., Kao, S., Wu, M. Y. & Lin, Y. F., Dec 1 2019, In : Scientific Reports. 9, 1, 2694.

Research output: Contribution to journalArticle

Open Access

An Open-Label, Multicenter, Phase I, Dose Escalation Study with Phase II Expansion Cohort to Determine the Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Intravenous TKM-080301 in Subjects with Advanced Hepatocellular Carcinoma

El Dika, I., Lim, H. Y., Yong, W. P., Lin, C. C., Yoon, J. H., Modiano, M., Freilich, B., Choi, H. J., Chao, T. Y., Kelley, R. K., Brown, J., Knox, J., Ryoo, B. Y., Yau, T. & Abou-Alfa, G. K., Jan 1 2019, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)
1 Citation (Scopus)
Open Access

Antrocin, a bioactive component from Antrodia cinnamomea, suppresses breast carcinogenesis and stemness via downregulation of β-catenin/Notch1/Akt signaling

Chen, J. H., T.H Wu, A., T.W Tzeng, D., Huang, C. C., Tzeng, Y. M. & Chao, T. Y., Jan 1 2019, In : Phytomedicine. 52, p. 70-78 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Appendix, an evolutionary vestigial linked to colorectal cancer

Wu, S. M., Lu, K. C., Lin, E. K., Chen, C. H. & Huang, C. J., Apr 3 2019, In : Scandinavian Journal of Gastroenterology. 54, 4, p. 478-479 2 p.

Research output: Contribution to journalLetter

Arginine vasopressin modulates electrical activity and calcium homeostasis in pulmonary vein cardiomyocytes

Huang, J. H., Chen, Y. C., Lu, Y. Y., Lin, Y. K., Chen, S. A. & Chen, Y. J., Sep 17 2019, In : Journal of Biomedical Science. 26, 1, 71.

Research output: Contribution to journalArticle

Open Access

ASPM promotes prostate cancer stemness and progression by augmenting Wnt−Dvl-3−β-catenin signaling

Pai, V. C., Hsu, C. C., Chan, T. S., Liao, W. Y., Chuu, C. P., Chen, W-Y., Li, C. R., Lin, C. Y., Huang, S. P., Chen, L. T. & Tsai, K. K., Feb 21 2019, In : Oncogene. 38, 8, p. 1340-1353 14 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
Open Access

Association between air pollution and risk of vascular dementia: A multipollutant analysis in Taiwan

Li, C. Y., Li, C. H., Martini, S. & Hou, W. H., Dec 2019, In : Environment International. 133, Pt B, 105233.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)
Open Access
1 Citation (Scopus)

Association of EGFR mutations and HMGB1 genetic polymorphisms in lung adenocarcinoma patients

Wu, Y. L., Chien, M. H., Chou, Y. E., Chang, J. H., Liu, T. C., Tsao, T. C. Y., Chou, M. C. & Yang, S. F., Jan 1 2019, In : Journal of Cancer. 10, 13, p. 2907-2914 8 p.

Research output: Contribution to journalArticle

Open Access
1 Citation (Scopus)

Association of endothelin genetic variants and hospitalized infection complications in end-stage renal disease (ESRD) patients

Kao, C. C., Cheng, S. Y., Wang, Y. J., Chien, S. C., Hsu, Y. W., Wu, M. Y., Lu, H. F., Nam, S., Sun, T., Wu, M. S. & Chang, W. C., Jun 5 2019, In : BMC Nephrology. 20, 1, p. 203 203.

Research output: Contribution to journalArticle

Open Access

Associations of gene polymorphisms in interferon-alpha signature-related genes with autoimmune thyroid diseases

Lin, J. D., Yang, S. F., Wang, Y. H., Fang, W. F., Tang, K. T. & Cheng, C. W., Dec 1 2019, In : Clinical Endocrinology. 91, 6, p. 860-868 9 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
1 Citation (Scopus)
Open Access
1 Citation (Scopus)

Bromelain inhibits the ability of colorectal cancer cells to proliferate via activation of ROS production and autophagy

Chang, T. C., Wei, P. L., Makondi, P. T., Chen, W. T., Huang, C. Y. & Chang, Y. J., Jan 1 2019, In : PLoS One. 14, 1, e0210274.

Research output: Contribution to journalArticle

4 Citations (Scopus)