Graduate Institute of Clinical Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2023

• 12 Active
• 404 Finished

Projects per year

Search results

• Finished

  Pathophysiology of Macrophage Migration Inhibitory Factor on Electrical and Structural Remodelings in Heart Failure-Induced Atrial Arrhythmogenesis

  Chen, Y.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heart Failure 100%
  • Atrial Fibrillation 95%
  • Atrial Remodeling 81%
  • Histone Deacetylases 68%
  • Pulmonary Veins 44%

• A Preclinical Study of the Therapeutic Targeting of Inflammatory-Cytokine-Addicted Cancer Stem Cells in Advanced Pancreatic Cancer

  Tsai, K. K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role and Molecular Mechanisms of N-Α-Acetyltransferase in Driving Tumor Invasion and Metastasis of Osteosarcoma

  Chien, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • osteosarcoma 100%
  • gelatinase A 66%
  • metastasis 59%
  • neoplasms 30%
  • acetyltransferases 21%

• 咽喉部疾病的危險因子及治療的流行病學研究

  Wang, Y.

  6/1/16 → 5/31/17

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 奈米藥物傳遞系統於治療慢性腎臟疾病之研究

  Chiu, H.

  6/1/16 → 5/31/17

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 糖尿病與手部肌肉骨骼症狀之關聯性探討：一個以族群為基礎之流行病學研究

  Hou, W.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• Edoxaban對於肺靜脈心肌組織及左心房肌之電生理特性及心律不整活性之調控

  Chen, Y.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 探討雄性素訊息相關蛋白參與降血糖藥物對腎臟保護的角色

  Chen, K.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 以組織工程活體保留未成熟睪丸生育能力 - 基因轉殖小鼠模式

  Chen, C.

  3/1/16 → 2/28/17

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• Investigation of the cerebral perfusion changes in patients with mild traumatic brain injury using 3D bSSFP arterial spin labeling MRI

  Liu, H., Tsai, P., Chen, C. & Lu, C.

  2/1/16 → 1/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study of the Molecular Mechanism Underlying Psat1-Induced Cancer Metastasis

  Lin, Y.

  1/1/16 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Metabolic 100%
  • Serine 77%
  • Biosynthesis 68%
  • Microarrays 44%
  • Drug Target 23%

• 新聘教師研究補助

  Chen, L.

  1/1/16 → 12/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• 臺北醫學大學附設醫院之疾病個案收集與建立臺灣人體生物資料庫

  Yen, Y.

  1/1/16 → 12/31/16

  Project: A - Government Institution › f - Other (Funded by Government)

• Establishing Health and Welfare Biotechnology Electronic Database Sharing Platform, Promoting Evidence-Based Medicine and Disseminating Technology Knowledge in Taiwan

  Chen, C., Tam, K., Chen, K., Hou, W. & Bai, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Healthcare 100%
  • evidence 76%
  • welfare 56%
  • ministry 47%
  • health 44%

• 105年度第二期癌症研究計畫-臺北醫學大學

  Yen, Y., Whang-Peng, J., Liu, L. & Chang, W.

  1/1/16 → 12/31/16

  Project: A - Government Institution › c - Ministry of Health and Welfare

  • Neoplasms 100%
  • Breast Neoplasms 71%
  • Antibodies 52%
  • Computational Biology 40%
  • Nicotine 34%

• 器官移植病患服用免疫抑制劑之流行病學研究

  Wang, Y.

  12/1/15 → 11/30/20

  Project: C - Project of Alliance › r - Tung's Taichung MetroHarbor Hospital

• Studies on the Carcinogenic Mechanisms of Glucose Transporters in Gastrointestinal Cancer Cells and Its Clinical Therapeutic Applications

  Chen, L. & Wu, C.

  9/1/15 → 8/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glucose 100%
  • Antitumor 19%
  • Occurrence in Nature 17%
  • Pharmacological Metabolism 11%
  • Biological Role 8%

• SOX2-Mediated Oncogenesis and Its Crosstalk with Environmental Risk Factors in Bladder Cancer

  Wang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Urinary Bladder Neoplasms 100%
  • Arsenic 24%
  • Stem Cells 23%
  • Neoplastic Stem Cells 22%
  • Cigarette Smoking 20%

• Relationship between Lumbar Vertebral Perfusion and Fat Marrow Content in Normal Subjects, Osteoporosis and Bone Metastases Using DCE-MRI and Fat-Water Separation

  Chan, W. P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Perfusion 100%
  • Bone Marrow 87%
  • Fats 39%
  • Osteoporosis 35%
  • Neoplasm Metastasis 32%

• Functional Investigation of Heat Shock Protein in Esophageal Squamous Cell Cancer with Implications in Prognostic Prediction and Therapeutic Targeting

  Tzao, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heat-Shock Proteins 100%
  • Esophageal Squamous Cell Carcinoma 56%
  • Neoplasms 33%
  • 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin 28%
  • Esophageal Neoplasms 24%

• Identification of Roles of microRNAs in Drug Resistance Development of Chronic Myeloid Leukemia

  Shih, C. & Liu, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Leukemia, Myelogenous, Chronic, BCR-ABL Positive 87%
  • Drug Resistance 40%
  • Imatinib Mesylate 29%
  • ran GTP-Binding Protein 29%

• The Comparison of Complications and Mortality after Surgery between General Anesthesia and Regional Anesthesia in the Elderly

  Liao, C., Cherng, Y. & Chen, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Conduction Anesthesia 100%
  • General Anesthesia 89%
  • Elderly 42%
  • Mortality 35%
  • Postoperative Complications 30%

• Association Study of Persistent Metabolic Syndrome, Inflammatory Markers, Adipose Markers and Mild Cognitive Decline

  Bai, C. & Hsu, R.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Cognitive Dysfunction 100%
  • Metabolic Syndrome 67%
  • Mental Status and Dementia Tests 50%
  • Thromboplastin 27%
  • Waist Circumference 24%

• Study of Expression and Functional Mechanisms of Histamine N-Methyltransferase (HNMT) in Tumorigenesis and Correlation with Progression in Lung Cancer

  Wang, L., Lee, W., Ho, Y. & Wu, A. T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histamine N-Methyltransferase 100%
  • Lung Neoplasms 43%
  • Carcinogenesis 18%
  • Neoplasms 10%
  • Genes 9%

• Preparation Mechanism and Application of Innovatively Plasmon-Induced Activated Liquid Water with Reduced Hydrogen-Bonded Structure

  Liu, Y. & Chang, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • hydrogen 100%
  • water 45%
  • nanoparticle 14%
  • medicine 12%
  • chemical reaction 9%

• Study the Therapeutic Effects and Novel Molecular Mechanisms of Resveratrol in Human Osteosarcoma---The Treatment of Metastatic Cancer

  Chien, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Resveratrol 100%
  • MicroRNA 72%
  • Microarrays 10%
  • Non Toxic 10%
  • Dose 7%

• The Development and Preclinical Evaluation of a Theronostic Nanovehicle Drug for Treating Acute Myeloid Leukemia and Leukemia Stem Cells (I)

  Yen, Y., Cheng, T. & Wu, A. T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Leukemia 100%
  • haptoglobin-hemoglobin complex 54%
  • Calicheamicins 53%
  • Neoplasms 49%
  • Multifunctional Nanoparticles 49%

• Studying on the Mechanism and Translational Application of Blocking the Protein-Protein Interaction between Galpha-h and PLC-delta1 in Combating Drug-Resistance and Metastasis of Triple-Negative Breast Cancer

  Lin, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • Drug Resistance 40%
  • Proteins 28%
  • Peptide Fragments 19%
  • Neoplasm Metastasis 18%

• Lipid Raft Associated Signaling in Regulation of Osteoclast Activation in Inflammatory Arthritis

  Tsai, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Osteoclasts 100%
  • Arthritis 34%
  • Osteogenesis 33%
  • Lipids 31%
  • Inflammation 28%

• Steroid and Antihistamin Synergize to Inhibit Rat’s Tracheal Smooth Muscle Contractility and Its Possible Mechanisms

  Wang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Smooth Muscle 100%
  • Histamine Antagonists 82%
  • Trachea 73%
  • levocetirizine 71%
  • Glucocorticoids 64%

• Systemic Analysis on Dynamic Mechanism of Actin Cytoskeleton Organization Regulated Physiological Changes Caused by Physical Stimuli in Mesenchymal Stem Cells

  Ho, J. & Chang, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Actins 100%
  • Mesenchymal Stem Cells 72%
  • Proteins 24%
  • Polymerization 22%
  • Microfilament Proteins 19%

• Electrophysiological and Molecular Insights into the Cardiac Regulations of ZFHX3 Gene---Implication in the Pathophysiology of Atrial Fibrillation

  Chen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Atrial Fibrillation 100%
  • MicroRNAs 68%
  • Calcium 48%
  • Electrophysiology 45%
  • Small Interfering RNA 34%

• Can Sesamin Alone or Cotheapy with Anti-DM Medicines Alleviate the Abnormal Intermediate Metabolites of Glucose and Fatty Acids, the Oxygen Consumption and Renal Fibrotic Progression?

  Peng, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • sesamin 100%
  • Oxygen Consumption 48%
  • Kidney 36%
  • Diabetic Nephropathies 20%
  • vascular factor 11%

• Application of Scaffold in Ovarian Transplantation for Female Fertility Preservation: an in vivo Transgenic Mouse Model (II)

  Chen, C., Tzeng, C. & Tseng, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • sphingosine 100%
  • vascular endothelial growth factors 67%
  • phosphates 52%
  • female fertility 30%
  • autografting 18%

• Effect of HMGA2 in Chemotherapy Response of Colorectal Cancer Patients with Different APC Status (II)

  Yen, Y., Cheng, Y. & Wei, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Bone-Marrow-Derived Mesenchymal Stem Cells in Prostate Cancer-Induced Bone Remodeling

  Hsieh, C., Chen, K. & Sung, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Adipogenic 100%
  • Osteogenic 37%

• A Mind-Body Approach to Study Irritable Bowel Syndrome: Role of Psychological Distress, Effectiveness and Mechanisms of Mindfulness Training(1/3)

  Tsai, P., Chang, C. & Chen, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Mindfulness 100%
  • Depression 82%
  • Anxiety 79%
  • Self-Help Groups 49%
  • Urbanization 35%

• Effects of Home-Based Exercise Training on Fatigue, Sleep Disturbance, Symptom Distress and Quality of Life in End-Stage Renal Disease Patients

  Lin, C., Chen, C., Lin, Y. & Wu, M.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Exercise 100%
  • Chronic Kidney Failure 90%
  • Quality of Life 77%
  • Sleep 53%
  • Dialysis 43%

• TMU103-AE1-B29

  Liu, H.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Radiogenomics of Malignant Gliomas by Linking Physiological Mr Imaging, Histopathological Patterns, and Genetic Alternations: a Translational Study from Rat to Man

  Chen, C., Tsai, P., Liu, H., Lin, Y. & Chiang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Glioblastoma 100%
  • Glioma 51%
  • Biomarkers 36%
  • Multiparametric Magnetic Resonance Imaging 15%
  • Neoplasms 14%

• Characterization of Thalamocortical Dysrhythmia in Mild Traumatic Brain Injury Using Simultaneous Mri and Eeg Measurements and Pre-Clinical N-Acetylcysteine Treatment Response

  Chen, C., Liu, H., Tseng, S., Lane, T. J., Lu, C., Chiang, Y. & Tsai, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Acetylcysteine 44%
  • Post-Concussion Syndrome 17%
  • Neuroimaging 15%
  • Electroencephalography 14%
  • Atrophy 9%

• Motion-Sensitive MR Imaging in Characterizing Brain Compliance in Cerebral Venous Hypertension: A Translational Study between Humans and Rats

  Lu, C., Liu, H., Chen, C. & Tsai, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Brain 100%
  • Cerebrospinal fluid 69%
  • Magnetic resonance 62%
  • Compliance 52%
  • Imaging techniques 46%

• Development of a Computerized Adaptive Testing of the Health Literacy in Stroke Rehabilitation.

  Hou, W. & Chen, S.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Health Literacy 100%
  • Stroke Rehabilitation 86%
  • Psychometrics 23%
  • Stroke 21%
  • Rehabilitation 19%

• Study of Postoperative Adverse Outcomes of Surgical Patients Using Taiwan National Health Insurance Database

  Chen, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Anesthesia 100%
  • Postoperative Complications 87%
  • Databases 61%
  • National Health Programs 53%
  • Taiwan 50%

• TMU103-AE1-B28

  Chiu, H.

  8/1/15 → 7/31/16

  Project: B - Project of TMU › i - Other (Funded by TMU)

• Kidney Injury and Heat Shock Protein Modulate the Atrial Electrophysiological Characterisitcs

  Hsieh, M., Chen, Y. & Lin, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Atrial Fibrillation 87%
  • Heat-Shock Proteins 68%
  • Indican 66%
  • Neomycin 41%

• Reflecting on Issues of End-Of-Life by Approaching Ventilator-Dependent Patients: an Interdisciplinary Educational Action Research

  Chen, C., Lin, W., Lin, S. & Tang, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • team teaching 100%
  • action research 70%
  • curriculum 64%
  • medicine 57%
  • dialogue 56%

• Cellular and Molecular Mechanisms with Epigenetic Regulation by Histone Deacetylation on Postopratetive Atrial and Pulmonary Vein Arrhythmogenesis

  Chen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylases 100%
  • Atrial Fibrillation 85%
  • Pulmonary Veins 63%
  • Calcium 44%
  • Heart Atria 40%

• Pitx2c Modulations on Atrial Fibroblast Activity, Electrical Characteristic, and Myocyte-Fibroblast Interaction: Implications in the Genesis of Atrial Fibrillation

  Kao, Y. & Chen, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibroblasts 100%
  • Atrial Fibrillation 36%
  • Electrophysiology 26%
  • Angiotensin II 22%
  • Cardiac Myocytes 21%

• Activation Autophagy by the Combination of a Histone Deacetylase Inhibitor and Radiation Limits BNIP3 Regulation in Triple-Negative Breast Cancer Cells and Orthotopic Mouse Model

  Chiu, H. & Ho, Y.

  8/1/15 → 6/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • Histone Deacetylase Inhibitors 97%
  • Ionizing Radiation 42%
  • Autophagy 39%
  • human ERBB2 protein 25%