Graduate Institute of Clinical Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2023

• 12 Active
• 404 Finished

Projects per year

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• Finished

  纖維芽細胞生成因子1對氧化誘導之氧化壓力、鈣平衡失調、和心律不整在肺靜脈的影響：一種新的心房顫動治療策略

  Chen, Y.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 推動新南向醫衛合作與產業鏈發展

  Kuo, H.

  2/11/19 → 12/11/19

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 癌症溫熱治療：利用臨床、實驗室與基因體學方法開發精準療效預測模組及最佳治療模式-建立人源性腫瘤移植動物平台測試腹腔惡性腫瘤溫熱化學治療成效及臨床療效預測模組開發

  Huang, C.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 雙打擊在瀰漫大B細胞淋巴瘤所扮演的角色-致病機轉與臨床特色之探討-篩選雙打擊瀰漫大B細胞淋巴瘤的新流程-根據台灣BCL6轉位之瀰漫大B細胞淋巴瘤的盛行狀況所提出的構想

  Chao, T.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 人性化的網路平台協助醫學資訊管理與報表產出-自動擷取資訊並基於規則之系統－應用於輸出骨密度及身體組成報告

  Chan, W. P.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 新穎癌幹原與免疫標靶療法於轉移性肝腫瘤的臨床前開發：臺北醫學大學全方位消化系腫瘤治療中心轉譯研究計畫-轉移性肝腫瘤Wnt 以及癌幹細胞標靶基因療法的臨床前開發 (第二年)

  Tsai, K. K.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 胃腸道腫瘤精準醫療奈米與免疫指標暨療法開發-2

  Tsai, K. K.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 運用人工智慧建構慢性疼痛患者長期監測及自我照顧的健康平台-發展智慧型手機和穿戴式裝置為基礎之慢性病痛患者監測系統

  Hou, W.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 108年度研究型主治醫師研究計畫-蔡坤志醫師

  Tsai, K. K.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• Taipei Medical University Speciality Equipment Service Plan

  Lin, S.

  12/1/18 → 12/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新聘教師研究補助

  Loh, E.

  11/1/18 → 10/31/20

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 胃腸道腫瘤精準醫療奈米與免疫指標暨療法開發-2

  Tsai, K. K.

  10/1/18 → 12/1/18

  Project: A - Government Institution › d - Ministry of Education

• Establishment of a Biophysical Effect-Based Platform for Rapid Expansion of Functional Mesenchymal Stem Cells(3/3)

  Ho, J.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • stromal cells 100%
  • stem cells 79%
  • cell transplantation 46%
  • microfluidic technology 39%
  • shear stress 32%

• Studies on the Mechanisms of Dna Primase（Prim1）Involved in Smoking-Induced Breast Cancer Formations and Its Translational Applications

  Chen, L.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Therapeutic Potentials of Peptide-Based Cytokine Binding Decoy against Sepsis and Its Effects on Modulating Inflammation, Oxidation, Apoptosis, Autophagy and Inflammasome

  Huang, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sepsis 100%
  • Peptides 37%
  • Cytokine Receptors 31%
  • Cytokines 24%
  • Inflammasomes 23%

• Therapeutic Potentials of Exosomes from Mesenchymal Stem Cell on Mitigating Cardiac Alterations and Their Effects on Modulating Oxidation, Inflammation, Mitochondrial Dysfunction and Insulin Resistance in Obesity Mice and Obesity Mice with Sepsis

  Huang, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study on the Roles of Unfolded Protein Response and Ubiquitin-Proteasome System in Radiotherapy Using Nanoparticle Drug Delivery in Triple-Negative Breast Cancer(3/3)

  Chiu, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • tubacin 87%
  • Endoplasmic Reticulum Stress 51%
  • Nucleotide Aptamers 40%
  • Proteasome Endopeptidase Complex 38%

• Galectins-Immune Signaling Reprograming in Atrial Remodeling and Arrhythmogenesis: a Novel Therapeutic Strategy for Atrial Fibrillation

  Chen, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Pathophysiology of Macrophage Migration Inhibitory Factor on Electrical and Structural Remodelings in Heart Failure-Induced Atrial Arrhythmogenesis(3/3)

  Chen, Y.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heart Failure 100%
  • Atrial Fibrillation 95%
  • Atrial Remodeling 81%
  • Histone Deacetylases 68%
  • Pulmonary Veins 44%

• Epigenetic Targeting for Potential Tumor Suppressor Genes, Poldip2 and Sox1, with Investigations of Prognostic and Therapeutic Implications in Non-Small Cell Lung Cancer

  Tzao, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanisms for Epithelium-Derived Interleukin 33 (Il-33) Up-Regulation and Its Effects on Circulating Fibrocyte Chemotaxis, Proliferation and Differentiation in Patients with Chronic Obstructive Asthma

  Kuo, H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Confounding Factors Associated with Immature Testicular Graft Survival for Fertility Preservation - Transgenic Mouse Model

  Chen, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • immatures 100%
  • spermatogenesis 43%
  • reperfusion injury 31%
  • image analysis 26%
  • drugs 21%

• 細胞外基質蛋白Nephronectin在腎小管細胞形成緊密連結的功能角色探討(2/2)

  Cheng, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • nephronectin 100%
  • Renal Cell Carcinoma 30%
  • Tight Junctions 25%
  • Neoplasm Metastasis 14%
  • Epithelial Cells 9%

• Investigation of Endoplasmic Reticulum Stress Response and Autophagy in Chronic Kidney Disease by Nanoparticle Drug Delivery System

  Lin, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 1. Cardiac Fibroblast Inhibition and Potential Treatment of Heart Failure: Histone Deacetylase Regulates the Mitochondria

  Kao, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Histone Deacetylases 100%
  • Fibroblasts 86%
  • Calcium 53%
  • Homeostasis 34%
  • Heart Failure 34%

• Identifying Gαh-Coupled Receptor and Studying on Its Translational Application in Triple-Negative Breast Cancer

  Lin, Y.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Triple Negative Breast Neoplasms 100%
  • Neoplasms 15%
  • Growth 13%
  • Neutralizing Antibodies 13%
  • Proteins 10%

• To Study the Role of Slc35b4 in the Progression of Colorectal Cancer and Molecular Mechanism

  Chang, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Protective Role of Hmg-Coa Reductase Inhibitor，Statins，In Postoperative Complications and Survival of Critically Ill Subjects(2/3)

  Chen, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Simultaneous Center-Periphery Neuroimaging for Data-Driven Rehabilitation Assessment of Fallers

  Chan, W. P.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effectiveness of Implementing Shared Decision-Making on Quality of Care among Patients with Lumbar Degenerative Diseases: a Cluster Randomized Controlled Trail(1/3)

  Hou, W.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Anti-Egfr×Anti-Fap Bi-Specific Targeting Antibody Combined with Irinotecan Encapsulated Liposomes for Pancreatic Cancer Therapy

  Lin, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Cross-Talk between Endothelial Cell-Specific Molecule-1 (Esm1) and Epidermal Growth Factor Receptor (Egfr) in the Progression of Non-Small-Cell Lung Cancer (Nsclc)(1/3)

  Chien, M.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Preclinical Study of the Therapeutic Targeting of Inflammatory-Cytokine-Addicted Cancer Stem Cells in Advanced Pancreatic Cancer

  Tsai, K. K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Aspm-Wnt Signaling in Hepatoma Cancer Stemness and Progression and the Development of the Related Nano- and Gene-Therapy(2/3)

  Tsai, K. K.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role and Molecular Mechanisms of N-Α-Acetyltransferase in Driving Tumor Invasion and Metastasis of Osteosarcoma(3/3)

  Chien, M.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • osteosarcoma 100%
  • gelatinase A 66%
  • metastasis 59%
  • neoplasms 30%
  • acetyltransferases 21%

• Using Arterial Spin Labeled Magnetic Resonance Imaging (Asl-Mri) to Evaluate Cerebral Blood Flow Changes in Patients with Chronic Kidney Disease(2/2)

  Liu, H.

  8/1/18 → 10/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Cerebrovascular Circulation 49%
  • Gadolinium 31%
  • Kidney 31%
  • Brain 28%

• 107年度研究型主治醫師研究計畫-蔡坤志醫師

  Tsai, K. K.

  7/1/18 → 12/31/18

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 探討肌醇單磷酸酶於亮細胞腎癌轉移所扮演之角色

  Chiu, H.

  5/1/18 → 4/30/19

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 構建以靜音核磁共振血管成像技術為基礎之定量化動脈血流量測

  Chan, W. P., 陳, 志., Chen, C. & Yang, S.

  3/1/18 → 2/28/19

  Project: D - Other Project

• 鴉片類藥物信號在肺靜脈心肌細胞致心律不整之作用與嗎啡誘導心房顫動的機轉探討

  Chen, Y.

  3/1/18 → 2/28/19

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• RGL2促進大腸/直腸癌抗藥性之轉譯醫學研究

  Lin, Y.

  3/1/18 → 2/28/19

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 探討AMPK/SREBP訊息調控Nifedipine於腎臟脂質沉積的角色

  Peng, C.

  3/1/18 → 2/28/20

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 建構人工智慧分類程序輔助電腦斷層影像自動檢測壓迫性骨折

  易謙, 呂., Chan, W. P., Chen, C., 木春, 蘇., Hung, K. & Lin, Y.

  3/1/18 → 2/28/19

  Project: D - Other Project

• Study of the roles of nuclear transcription factor Y (NF-Y) in human hepatocellular carcinoma

  Chien, M.

  3/1/18 → 2/28/19

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 新穎癌幹原與免疫標靶療法於轉移性肝腫瘤的臨床前開發：臺北醫學大學全方位消化系腫瘤治療中心轉譯研究計畫

  Tsai, K. K.

  1/1/18 → 12/31/18

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 新聘教師研究補助

  Huang, C.

  1/1/18 → 12/31/18

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 臺北醫學大學自有貴重儀器共用服務計畫

  Lin, S.

  12/1/17 → 12/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Therapeutic Potentials of Peptide-Based Cytokine Binding Decoy against Sepsis and Its Effects on Modulating Inflammation, Oxidation, Apoptosis, Autophagy and Inflammasome

  Huang, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Sepsis 100%
  • Peptides 37%
  • Cytokine Receptors 31%
  • Cytokines 24%
  • Inflammasomes 23%

• Epigenetic Targeting for Potential Tumor Suppressor Genes, Poldip2 and Sox1, with Investigations of Prognostic and Therapeutic Implications in Non-Small Cell Lung Cancer

  Tzao, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Evaluation the Cotherapeutic Ginkgo Biloba Plus Metformin against the Methylglyoxal-Induced Renal Tubular Lipotoxicity and Cellular Senescence in Cell Cycle via Srebp and Ppar Pathways

  Peng, C.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Ginkgo biloba extract 100%
  • Kidney 82%
  • Cellular Senescence 64%
  • Metformin 50%
  • Pyruvaldehyde 33%