Graduate Institute of Clinical Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2023

• 12 Active
• 404 Finished

Projects per year

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• Finished

  探討 CWH43 大腸直腸癌發展的角色及其調控機制

  Chang, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 間質幹細胞之外泌體於減緩肥胖及肥胖併發敗血症於小鼠所致心臟病變之療效與其調控氧化、發炎、粒線體異常及胰島素抵抗之效應探討(3/3)

  Huang, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 絲氨酸/蘇氨酸蛋白激酶(SIK3)參與乳癌致癌過程的分子機制探討

  Chen, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• anti-EGFR×anti-FAP雙辨識特異性抗體結合包覆抗癌藥物Irinotecan標靶微脂體治療胰臟癌之研究(3/3)

  Lin, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 電漿活化水對潰瘍性大腸炎及克隆氏症等腸道炎症微生物菌叢的影響-由藥物誘導鼠及基因轉殖鼠探討(2/2)

  Chang, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• ASPM-PAR-PCP訊息軸於侵犯性癌幹細胞造成癌轉移的角色與其標靶治療(2/3)

  Tsai, K. K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討KH-Type切割調控蛋白在腎細胞癌惡性進程中所扮演的角色(1/3)

  Chien, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 以anti-FAP/anti-CD3雙功能抗體武裝之毒殺型T細胞搭配臨床化療藥物治療腫瘤纖維化之胰臟癌

  Lin, S.

  7/1/20 → 2/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討內皮素誘發NLRP3發炎體於慢性腎臟疾病之角色

  Chiu, H.

  5/1/20 → 4/30/21

  Project: C - Project of Alliance › p - Taipei Medical University Hospital

• 探討經PGC1-α調控粒線體動態參與Bicalutamide所引致的細胞凋亡

  Peng, C.

  3/1/20 → 2/1/21

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 探討SH2 Domain Containing 5 (SH2D5)促進大腸癌細胞進程之分子機轉

  Lin, Y.

  3/1/20 → 2/1/21

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 探討第一型內皮細胞分子胃癌進程之角色及相關調控機制

  Chien, M.

  3/1/20 → 2/1/21

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 改善於電性重塑引發氧化壓力及細胞內鈣離子調控異常作為心房纖維顫動治療策略的研究

  Kao, Y.

  3/1/20 → 2/1/21

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 研究BTK/HER2信號通路在HER2陽性乳腺癌生物特性角色：調控T細胞的效應及逆轉賀癌平抗藥性的分子機制

  Chao, T.

  1/1/20 → 12/31/20

  Project: A - Government Institution › a - National Health Research Institutes

• 數位化乳房攝影鈣化特異性之人工智能深度學習及分析

  Chan, W. P.

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 2-1-3 精進核心研究服務平台-胃腸道腫瘤精準醫療奈米與免疫指標暨療法開發

  Tsai, K. K.

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• ASPM與Wnt訊息傳導在肝癌幹原性與惡化以及相關奈米基因治療之開發

  Tsai, K. K.

  1/1/20 → 12/31/20

  Project: A - Government Institution › a - National Health Research Institutes

• 乳房影像報告人工智慧醫療助理第一期發展計畫

  Loh, E.

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 降血壓藥物(angiotensin-converting enzyme inhibitor, ACEI)對降低缺血性中風患者的神經性退化性疾病及其死亡率之療效評估：以帕金森氏症及失智症為例

  Chen, T.

  1/1/20 → 12/1/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 新聘教師研究補助

  Shen, Y.

  9/1/19 → 8/31/20

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• Effectiveness of Implementing Shared Decision-Making on Quality of Care among Patients with Lumbar Degenerative Diseases: a Cluster Randomized Controlled Trail(2/3)

  Hou, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Role of Btk/Her2 Signaling as a Therapeutic Target for Restoration of T Cell Function and Reversal of Trastuzumab Resistance in Her2+ Breast Cancer(1/3)

  Chao, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Plasmon-Activated Water on the Microbiota of Inflammatory Bowel Disease, Crohn’S Disease and Ulcerative Colitis, by Drug-Induced and Transgenic Mouse Models

  Chang, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanisms for Epithelium-Derived Interleukin 33 (Il-33) Up-Regulation and Its Effects on Circulating Fibrocyte Chemotaxis, Proliferation and Differentiation in Patients with Chronic Obstructive Asthma(3/3)

  Kuo, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Metronomic Chemotherapy Potentiates Immuno-Surveillance and Immunotherapy in Desmoplastic Pancreatic Cancer: Focusing on the Roles of Tumor Stroma and Myeloid-Derived Suppressor Cells( I )(1/3)

  Tsai, K. K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Cross-Talk between Endothelial Cell-Specific Molecule-1 (Esm1) and Epidermal Growth Factor Receptor (Egfr) in the Progression of Non-Small-Cell Lung Cancer (Nsclc)

  Chien, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Aspm-Wnt Signaling in Hepatoma Cancer Stemness and Progression and the Development of the Related Nano- and Gene-Therapy

  Tsai, K. K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Mechanisms of Dna Primase（Prim1）Involved in Smoking-Induced Breast Cancer Formations and Its Translational Applications

  Chen, L.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Therapeutic Potentials of Exosomes from Mesenchymal Stem Cell on Mitigating Cardiac Alterations and Their Effects on Modulating Oxidation, Inflammation, Mitochondrial Dysfunction and Insulin Resistance in Obesity Mice and Obesity Mice with Sepsis

  Huang, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Epigenetic Targeting for Potential Tumor Suppressor Genes, Poldip2 and Sox1, with Investigations of Prognostic and Therapeutic Implications in Non-Small Cell Lung Cancer(3/3)

  Tzao, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Sub-Project 3: Predicting Rehabilitation Effectiveness on Incomplete Spinal Cord Injured Patients: Longitudinal Multi-Modal Neuroimaging Evaluation of Paired Associative Nerve Stimulation( I )

  Chan, W. P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Simultaneous Center-Periphery Neuroimaging for Data-Driven Rehabilitation Assessment of Fallers(2/3)

  Chan, W. P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Galectins-Immune Signaling Reprograming in Atrial Remodeling and Arrhythmogenesis: a Novel Therapeutic Strategy for Atrial Fibrillation(2/3)

  Chen, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanistic Insights into Scn5a Deficiency on Fibrogenesis: Implications in Channelopathy Induced Structure Remodeling

  Kao, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Endoplasmic Reticulum Stress Response and Autophagy in Chronic Kidney Disease by Nanoparticle Drug Delivery System

  Lin, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Anti-Egfr×Anti-Fap Bi-Specific Targeting Antibody Combined with Irinotecan Encapsulated Liposomes for Pancreatic Cancer Therapy(2/3)

  Lin, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Drug Delivery by Nano Scaffold Improved Immature Testicular Tissue Graft Survival Rate -A Transgenic Mouse Model

  Chen, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Aspm-Par-Pcp Signaling in Invasive-Cancer-Stem-Cell-Mediated Metastasis and Its Therapeutic Targeting(1/3)

  Tsai, K. K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Characterization of Glioblastoma Using Advanced Multimodal Small Animal Mr Imaging Techniques

  Liu, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Utilizing Artificial Intelligence Vi Rtual Screening Platform to Identify a Small-Molecule Inhibitor of Dna Polymerase Theta and Estimating Its Therapeutic Effectiveness on Metastatic Castration-Resistant Prostate Cancer

  Lin, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Role of Slc35b4 in the Progression of Colorectal Cancer and Molecular Mechanism

  Chang, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Protective Role of Hmg-Coa Reductase Inhibitor，Statins，In Postoperative Complications and Survival of Critically Ill Subjects(3/3)

  Chen, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Could Bicalutamide–Induced Renal Fibrosis Take the Pathway Tgf-B1/Wnt That Further Triggers Mesangial Mitochondrial Dysfunction and Metabolic Reprogramming? - Evaluation of Prognosis on Cotherapy of Nac, Nad+, Riboflavin, and Coq?

  Peng, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討乳糖鐵蛋白於腎臟疾病的保護效果

  Chiu, H.

  5/1/19 → 4/30/20

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 開發帶有免疫提升佐劑之明膠微粒膠體劑型

  Lin, S.

  4/2/19 → 11/2/19

  Project: D - Other Project

• 建立中風病人主動參與醫病共享決策的友善支持系統

  Hou, W.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 利用全基因定序尋找肝癌其體細胞突變基因和基因多型性與環境因子之關聯-聚焦於長鏈非編碼核糖核酸MALAT1之基因多型性探討

  Chien, M.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 探討NEDD8促進口腔癌細胞之放射線療法抗性的分子機轉

  Lin, Y.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 利用細胞模型來探索在腸胃癌中CSE1L、p53與 DNA ploidy的相互作用

  Chang, C.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › q - Cathay General Hospital

• 馬兜鈴酸相關上泌尿道上皮癌之DNA甲基化生物標記研究

  Wang, Y.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › o - Chi Mei Medical Center