Graduate Institute of Clinical Medicine

Projects

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• 11 Active
• 403 Finished

Projects per year

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• Finished

  精準醫學臨床模組開發_開發可預測結核病患者治療反應和疾病進展的血清標記蛋白

  Putri, D. U.

  1/1/22 → 12/31/22

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 糖尿病所致慢性腎臟病變發展:尿液暨血液外泌體多體學分析與創新生物標記開發

  Huang, C.

  1/1/22 → 12/31/22

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 間質幹細胞療法治療 COVID-19引起的急性呼吸窘迫綜合症的個人化監測

  Putri, D. U.

  1/1/22 → 12/31/22

  Project: C - Project of Alliance › t - Taipei Municipal Wanfang Hospital

• 2-1-3 精進核心研究服務平台-研究型主治醫師蔡坤志

  Tsai, K. K.

  1/1/22 → 12/31/22

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 新穎癌幹細胞侵犯腳治療標靶之整合性蛋白質體、基因體、小分子與功能篩選：聚焦細胞表面AMFR於侵犯性消化道癌症治療標的(2/3)

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 進展性胰臟癌新穎增進免疫療法的治療策略與生物指標-節拍式化學治療增進基質硬化性胰臟癌免疫監督與免疫檢查點阻斷療法: 聚焦於腫瘤基質與髓源性抑制細胞(3/3)

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 奈米控釋介導間質幹細胞外泌體合併細胞激素結合誘餌胜?與微囊蛋白-1支架領域胜?之三功能協同創新療法於治療肥胖併發敗血症所致器官傷害與死亡之療效: 聚焦細胞死亡相關機轉(1/2)

  Huang, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討新型冠狀病毒棘狀蛋白S1誘導心臟電生理及結構性重塑之病理機制：治療新型冠狀肺炎引發心臟損傷之新契機

  Kao, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討G-CSF於膀胱癌腫瘤微環境所扮演的角色及分子機制

  Wang, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 針對IL-33/ST2訊息路徑調控鈣平衡、內質網壓力與粒線體功能作為心房與肺靜脈心律不整活性與心房顫動致病機轉及治療策略探討(2/3)

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用人工智慧虛擬篩選平台鑑定DNA聚合酶theta之小分子抑制劑和評估其對於轉移型去勢抗性之攝護腺癌的治療效果(3/3)

  Lin, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究BTK/HER2信號通路在HER2陽性乳腺癌生物特性角色: 調控T細胞的效應及逆轉賀癌平抗藥性的分子機制(3/3)

  Chao, T.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討在慢性腎臟疾病中經由抑制內皮素轉化?調節前列腺素E2受體和自體吞噬作用的治療潛力之機轉(2/3)

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討腎臟細胞暴露於塑膠微粒和塑膠奈米中誘發自體吞噬作用和增加SREBPs並引起血管內皮細胞滲漏作用之機制(2/3)

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• FGF9在急性腎損傷與發展至慢性腎臟病進程之角色探討(1/3)

  Cheng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• ASPM-PAR-PCP訊息軸於侵犯性癌幹細胞造成癌轉移的角色與其標靶治療(3/3)

  Tsai, K. K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討KH-Type切割調控蛋白在腎細胞癌惡性進程中所扮演的角色(2/3)

  Chien, M.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討腎臟細胞暴露於塑膠微粒和塑膠奈米中誘發自體吞噬作用和增加SREBPs並引起血管內皮細胞滲漏作用之機制(2/3)

  Chiu, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 攝護腺癌經PGC1α/SIRT3/ETC Complexes調節粒線體動態及代謝重整促進腫瘤細胞存活及侵襲性之探討-以SIRT3調節劑減緩化學抗藥性之策略評估

  Peng, C.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 自體免疫心肌炎引起心室心律不整及鈣離子調控失衡、粒線體異常與NLRP3/MIF發炎體訊息路徑活化之致病機轉及治療策略探討(1/3)

  Chen, Y.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 細胞毒性T淋巴細胞相關蛋白4基因多形性對罹患乳癌風險之影響：系統性文獻回顧與統合分析

  Wang, Y.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 一種新穎的靜脈注射擬鈣劑改善慢性腎臟疾病-礦物質骨病變的骨轉換率

  Chiu, H.

  5/1/21 → 4/30/22

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 以細胞模式研究的第IIA期大腸直腸癌術後復發基因標誌的精準醫學

  Chang, C.

  3/1/21 → 2/28/22

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 評估在三陰性乳癌中阻斷OTUD7B相關之訊息傳遞軸對於增強太平洋紫杉醇敏感度與抑制轉移能力的效果

  Lin, Y.

  3/1/21 → 2/28/22

  Project: C - Project of Alliance › s - Shin Kong Wu Ho-Su Memorial Hospital

• 性別差異對Brugada綜合病徵在細胞和分子機轉差異性的研究:藉由鋰中毒誘發新穎型實驗動物模型

  Chen, Y.

  3/1/21 → 2/28/22

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 乳房影像報告人工智慧醫療助理第一期發展計畫

  Loh, E.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 數位化乳房攝影鈣化特異性之人工智能深度學習及分析

  Chan, W. P.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• Sirtuin 1 對小鼠心律不整及心房顫動之影響及鈣離子與電生理之調控

  Kao, Y.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 降血壓藥物(angiotensin-converting enzyme inhibitor, ACEI)對降低缺血性中風患者的神經性退化性疾病及其死亡率之療效評估：以帕金森氏症及失智症為例

  Chen, T.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 攜帶Rrm2b質體的奈米載體系統用於治療慢性腎臟疾病的潛力研究

  Chiu, H.

  1/1/21 → 12/31/21

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 城市角落苗圃：設計思考化跨域教與學

  Chu, J.

  12/1/20 → 5/31/21

  Project: A - Government Institution › d - Ministry of Education

• 探討Sirtuin 1 訊息路徑作為心房顫動致病機轉及新治療策略

  Kao, Y.

  10/1/20 → 12/31/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 攜帶Rrm2b質體的奈米載體系統用於治療慢性腎臟疾病的潛力研究

  Chiu, H.

  10/1/20 → 12/31/20

  Project: B - Project of TMU › h - Higher Education Sprout Project

• 利用人工智慧虛擬篩選平台鑑定DNA聚合?theta之小分子抑制劑和評估其對於轉移型去勢抗性之攝護腺癌的治療效果(2/3)

  Lin, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Bicalutamide經Sirt3/p53引發腎膈細胞電子傳遞鏈複合體I缺陷而致細胞凋亡機制的探討-輔以Idebenone及MitoTempo提升氧化磷酸化系統及調節粒線體動態之治療策略評估

  Peng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 調控半乳糖凝集素之免疫訊號重整作用對心房再塑與心律不整活性的病理機轉探討：一個新的治療心房顫動契機(3/3)

  Chen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 纖維細胞生長因子與其受體之訊息路徑在急性腎損傷中維持腎臟血管結構能力之角色研究

  Cheng, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• anti-EGFR×anti-FAP雙辨識特異性抗體結合包覆抗癌藥物Irinotecan標靶微脂體治療胰臟癌之研究(3/3)

  Lin, S.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 針對IL-33/ST2訊息路徑調控鈣平衡、內質網壓力與粒線體功能作為心房與肺靜脈心律不整活性與心房顫動致病機轉及治療策略探討(1/3)

  Chen, Y.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 間質幹細胞之外泌體於減緩肥胖及肥胖併發敗血症於小鼠所致心臟病變之療效與其調控氧化、發炎、粒線體異常及胰島素抵抗之效應探討(3/3)

  Huang, C.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討KH-Type切割調控蛋白在腎細胞癌惡性進程中所扮演的角色(1/3)

  Chien, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 利用多模式小動物進階磁振造影技術定量膠質母細胞瘤之研究(2/2)

  Liu, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 發展以同步量測中樞與周邊系統功能性訊息為導向之年長跌倒患者步態復健評估(3/3)

  Chan, W. P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 絲氨酸/蘇氨酸蛋白激酶(SIK3)參與乳癌致癌過程的分子機制探討

  Chen, L.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新穎癌幹細胞侵犯腳治療標靶之整合性蛋白質體、基因體、小分子與功 能篩選：聚焦細胞表面AMFR於侵犯性消化道癌症治療標的(1/3)

  Tsai, K. K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• ASPM-PAR-PCP訊息軸於侵犯性癌幹細胞造成癌轉移的角色與其標靶治療(2/3)

  Tsai, K. K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 進展性胰臟癌新穎增進免疫療法的治療策略與生物指標-節拍式化學治療增進基質硬化性胰臟癌免疫監督與免疫檢查點阻斷療法: 聚焦於腫瘤基質與髓源性抑制細胞(2/3)

  Tsai, K. K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討第一型內皮細胞分子與上皮細胞生長因子受體之相互調控在非小細胞肺癌進程之角色(3/3)

  Chien, M.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 研究BTK/HER2信號通路在HER2陽性乳腺癌生物特性角色: 調控T細胞的效應及逆轉賀癌平抗藥性的分子機制(2/3)

  Chao, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討腎臟細胞暴露於塑膠微粒和塑膠奈米中誘發自體吞噬作用和增加SREBPs並引起血管內皮細胞滲漏作用之機制(1/3)

  Chiu, H.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology