Graduate Institute of Clinical Medicine

Projects

Projects per year 2010 2013 2014 2015 2016 2017 2018 2019 2020 2022

• 19 Active
• 383 Finished

Projects per year

Search results

• Finished

  Investigation of Endoplasmic Reticulum Stress Response and Autophagy in Chronic Kidney Disease by Nanoparticle Drug Delivery System

  Lin, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Cross-Talk between Endothelial Cell-Specific Molecule-1 (Esm1) and Epidermal Growth Factor Receptor (Egfr) in the Progression of Non-Small-Cell Lung Cancer (Nsclc)

  Chien, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Aspm-Wnt Signaling in Hepatoma Cancer Stemness and Progression and the Development of the Related Nano- and Gene-Therapy

  Tsai, K. K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Plasmon-Activated Water on the Microbiota of Inflammatory Bowel Disease, Crohn’S Disease and Ulcerative Colitis, by Drug-Induced and Transgenic Mouse Models

  Chang, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Role of Slc35b4 in the Progression of Colorectal Cancer and Molecular Mechanism

  Chang, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Drug Delivery by Nano Scaffold Improved Immature Testicular Tissue Graft Survival Rate -A Transgenic Mouse Model

  Chen, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effectiveness of Implementing Shared Decision-Making on Quality of Care among Patients with Lumbar Degenerative Diseases: a Cluster Randomized Controlled Trail(2/3)

  Hou, W.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Metronomic Chemotherapy Potentiates Immuno-Surveillance and Immunotherapy in Desmoplastic Pancreatic Cancer: Focusing on the Roles of Tumor Stroma and Myeloid-Derived Suppressor Cells( I )(1/3)

  Tsai, K. K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigating the Role of Btk/Her2 Signaling as a Therapeutic Target for Restoration of T Cell Function and Reversal of Trastuzumab Resistance in Her2+ Breast Cancer(1/3)

  Chao, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Galectins-Immune Signaling Reprograming in Atrial Remodeling and Arrhythmogenesis: a Novel Therapeutic Strategy for Atrial Fibrillation(2/3)

  Chen, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Epigenetic Targeting for Potential Tumor Suppressor Genes, Poldip2 and Sox1, with Investigations of Prognostic and Therapeutic Implications in Non-Small Cell Lung Cancer(3/3)

  Tzao, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Characterization of Glioblastoma Using Advanced Multimodal Small Animal Mr Imaging Techniques

  Liu, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Mechanisms of Dna Primase（Prim1）Involved in Smoking-Induced Breast Cancer Formations and Its Translational Applications

  Chen, L.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Simultaneous Center-Periphery Neuroimaging for Data-Driven Rehabilitation Assessment of Fallers(2/3)

  Chan, W. P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Therapeutic Potentials of Exosomes from Mesenchymal Stem Cell on Mitigating Cardiac Alterations and Their Effects on Modulating Oxidation, Inflammation, Mitochondrial Dysfunction and Insulin Resistance in Obesity Mice and Obesity Mice with Sepsis

  Huang, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Anti-Egfr×Anti-Fap Bi-Specific Targeting Antibody Combined with Irinotecan Encapsulated Liposomes for Pancreatic Cancer Therapy(2/3)

  Lin, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Mechanisms for Epithelium-Derived Interleukin 33 (Il-33) Up-Regulation and Its Effects on Circulating Fibrocyte Chemotaxis, Proliferation and Differentiation in Patients with Chronic Obstructive Asthma(3/3)

  Kuo, H.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Protective Role of Hmg-Coa Reductase Inhibitor，Statins，In Postoperative Complications and Survival of Critically Ill Subjects(3/3)

  Chen, T.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Sub-Project 3: Predicting Rehabilitation Effectiveness on Incomplete Spinal Cord Injured Patients: Longitudinal Multi-Modal Neuroimaging Evaluation of Paired Associative Nerve Stimulation( I )

  Chan, W. P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of Aspm-Par-Pcp Signaling in Invasive-Cancer-Stem-Cell-Mediated Metastasis and Its Therapeutic Targeting(1/3)

  Tsai, K. K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Could Bicalutamide–Induced Renal Fibrosis Take the Pathway Tgf-B1/Wnt That Further Triggers Mesangial Mitochondrial Dysfunction and Metabolic Reprogramming? - Evaluation of Prognosis on Cotherapy of Nac, Nad+, Riboflavin, and Coq?

  Peng, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Utilizing Artificial Intelligence Vi Rtual Screening Platform to Identify a Small-Molecule Inhibitor of Dna Polymerase Theta and Estimating Its Therapeutic Effectiveness on Metastatic Castration-Resistant Prostate Cancer

  Lin, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討乳糖鐵蛋白於腎臟疾病的保護效果

  Chiu, H.

  5/1/19 → 4/30/20

  Project: C - Project of Alliance › u - Taipei Medical University Shuang Ho Hospital

• 開發帶有免疫提升佐劑之明膠微粒膠體劑型

  Lin, S.

  4/2/19 → 11/2/19

  Project: D - Other Project

• 纖維芽細胞生成因子1對氧化誘導之氧化壓力、鈣平衡失調、和心律不整在肺靜脈的影響：一種新的心房顫動治療策略

  Chen, Y.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 利用全基因定序尋找肝癌其體細胞突變基因和基因多型性與環境因子之關聯-聚焦於長鏈非編碼核糖核酸MALAT1之基因多型性探討

  Chien, M.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 探討NEDD8促進口腔癌細胞之放射線療法抗性的分子機轉

  Lin, Y.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › n - Yuan's General Hospital

• 建立中風病人主動參與醫病共享決策的友善支持系統

  Hou, W.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 利用細胞模型來探索在腸胃癌中CSE1L、p53與 DNA ploidy的相互作用

  Chang, C.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › q - Cathay General Hospital

• 馬兜鈴酸相關上泌尿道上皮癌之DNA甲基化生物標記研究

  Wang, Y.

  3/1/19 → 2/1/20

  Project: C - Project of Alliance › o - Chi Mei Medical Center

• 推動新南向醫衛合作與產業鏈發展

  Kuo, H.

  2/11/19 → 12/11/19

  Project: A - Government Institution › c - Ministry of Health and Welfare

• 人性化的網路平台協助醫學資訊管理與報表產出-自動擷取資訊並基於規則之系統－應用於輸出骨密度及身體組成報告

  Chan, W. P.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 108年度研究型主治醫師研究計畫-蔡坤志醫師

  Tsai, K. K.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 運用人工智慧建構慢性疼痛患者長期監測及自我照顧的健康平台-發展智慧型手機和穿戴式裝置為基礎之慢性病痛患者監測系統

  Hou, W.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 癌症溫熱治療：利用臨床、實驗室與基因體學方法開發精準療效預測模組及最佳治療模式-建立人源性腫瘤移植動物平台測試腹腔惡性腫瘤溫熱化學治療成效及臨床療效預測模組開發

  Huang, C.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 胃腸道腫瘤精準醫療奈米與免疫指標暨療法開發-2

  Tsai, K. K.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 新穎癌幹原與免疫標靶療法於轉移性肝腫瘤的臨床前開發：臺北醫學大學全方位消化系腫瘤治療中心轉譯研究計畫-轉移性肝腫瘤Wnt 以及癌幹細胞標靶基因療法的臨床前開發 (第二年)

  Tsai, K. K.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• 雙打擊在瀰漫大B細胞淋巴瘤所扮演的角色-致病機轉與臨床特色之探討-篩選雙打擊瀰漫大B細胞淋巴瘤的新流程-根據台灣BCL6轉位之瀰漫大B細胞淋巴瘤的盛行狀況所提出的構想

  Chao, T.

  1/1/19 → 12/1/19

  Project: A - Government Institution › d - Ministry of Education

• Taipei Medical University Speciality Equipment Service Plan

  Lin, S.

  12/1/18 → 12/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• 新聘教師研究補助

  Loh, E.

  11/1/18 → 10/31/20

  Project: B - Project of TMU › g - Research Grants for Newly Hired Faculty

• 胃腸道腫瘤精準醫療奈米與免疫指標暨療法開發-2

  Tsai, K. K.

  10/1/18 → 12/1/18

  Project: A - Government Institution › d - Ministry of Education

• Anti-Egfr×Anti-Fap Bi-Specific Targeting Antibody Combined with Irinotecan Encapsulated Liposomes for Pancreatic Cancer Therapy

  Lin, S.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Simultaneous Center-Periphery Neuroimaging for Data-Driven Rehabilitation Assessment of Fallers

  Chan, W. P.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Using Arterial Spin Labeled Magnetic Resonance Imaging (Asl-Mri) to Evaluate Cerebral Blood Flow Changes in Patients with Chronic Kidney Disease(2/2)

  Liu, H.

  8/1/18 → 10/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Renal Insufficiency 100%
  • Cerebrovascular Circulation 49%
  • Gadolinium 31%
  • Kidney 31%
  • Brain 28%

• 細胞外基質蛋白Nephronectin在腎小管細胞形成緊密連結的功能角色探討(2/2)

  Cheng, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • nephronectin 100%
  • Renal Cell Carcinoma 30%
  • Tight Junctions 25%
  • Neoplasm Metastasis 14%
  • Epithelial Cells 9%

• Pathophysiology of Macrophage Migration Inhibitory Factor on Electrical and Structural Remodelings in Heart Failure-Induced Atrial Arrhythmogenesis(3/3)

  Chen, Y.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Heart Failure 100%
  • Atrial Fibrillation 95%
  • Atrial Remodeling 81%
  • Histone Deacetylases 68%
  • Pulmonary Veins 44%

• The Role of Aspm-Wnt Signaling in Hepatoma Cancer Stemness and Progression and the Development of the Related Nano- and Gene-Therapy(2/3)

  Tsai, K. K.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Preclinical Study of the Therapeutic Targeting of Inflammatory-Cytokine-Addicted Cancer Stem Cells in Advanced Pancreatic Cancer

  Tsai, K. K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Study the Role of Slc35b4 in the Progression of Colorectal Cancer and Molecular Mechanism

  Chang, Y.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Mechanisms of Dna Primase（Prim1）Involved in Smoking-Induced Breast Cancer Formations and Its Translational Applications

  Chen, L.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology