Division of Thoracic Medicine

Projects

Projects per year 2010 2012 2013 2014 2015 2020 2021 2022

• 6 Active
• 99 Finished

Projects per year

Search results

• a - National Health Research Institutes

  針對表皮生長因子受體研發肺癌治療之抑制型胜肽藥物

  Lin, E. P.

  1/1/21 → 12/31/21

  Project: A - Government Institution › a - National Health Research Institutes

• 探討CD155/TIGIT在類骨髓衍生抑制細胞/腫瘤衍生巨噬細胞誘導自然殺手細胞失調的機轉-研究肺癌病人免疫檢查點阻斷藥物抗藥性機轉

  Feng, P.

  1/1/20 → 2/28/21

  Project: A - Government Institution › a - National Health Research Institutes

• b - Ministry of Science and Technology

  血中的纖維細胞在嚴重氣喘患者扮演第二型細胞激素嶄新的細胞來源其臨床相關性與調控機制(2/3)

  Kuo, H.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 粒狀空氣污染物所產生的氧化壓力對慢性阻塞性肺疾病患者的泛素-蛋白酉每平衡系統之影響:探討氧化壓力，異常發炎以及蛋白質氧化之關係

  Chuang, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The effect of endothelin-1 on myofibroblast transformation of pleural mesothelial cells and its implications for pleural and pulmonary fibrosis

  Chung, C.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Myofibroblasts 100%
  • Endothelin-1 85%
  • Fibrosis 70%
  • Pulmonary Fibrosis 54%
  • Epithelial-Mesenchymal Transition 49%

• 腫瘤相關巨噬細胞在誘發產生表皮生長因子受器酪胺酸酉每抑制劑的抗藥性的角色

  Feng, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Imapct of Oxidative Stress on the Pathogenesis of COPD---An Ivestigation into Its Relationship with Abnormal Inflammation, Dna Instability, Epigenetics and Cell Metabolism

  Lee, K.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Oxidative Stress 47%
  • Inflammation 33%
  • Blood Cells 26%
  • Glucocorticoids 21%

• 三維仿肺呼吸功能實驗室晶片之研發以應用於空污誘發哮喘過敏與肺癌免疫治療研究(2/2)

  Lee, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Tumor Microenvironment Induced Egfr-Tki Resistance

  Feng, P.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • ErbB Receptors 100%
  • Adenocarcinoma of Lung 37%
  • Macrophages 36%
  • Tumor Microenvironment 36%
  • Neoplasms 33%

• CAAT/enhancer binding protein beta訊息路徑參與thrombin誘導人類肺部上皮細胞IL-8/ CXCL8表現之研究

  Chen, B.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of ADAM 17 in Hypoxia-Induced CTGF Expression and Pulmonary Fibrosis (II)

  Chen, B.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies of Cxcl12 in Hypoxia-Induced Pulmonary Fibrosis

  Chen, B.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hypoxia 100%
  • Pulmonary Fibrosis 62%
  • Fibroblasts 58%
  • Lung 55%
  • Phosphatidylinositol 3-Kinases 35%

• Immune Alteration and Immunogenic Cell Death in Advanced Non-Small Cell Lung Cancer Patients

  Feng, P.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Myeloid-Derived Suppressor Cells 100%
  • Immunogenic Cell Death 67%
  • Lung Neoplasms 59%
  • Drug Therapy 56%
  • Neoplasms 24%

• 針對肺癌轉移中樞神經系統發展特定適體(2/2)

  Lin, E. P.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Investigation of Chromatin Remodeling and Akt-Dependnet mTOR/S6K Mediate Thrombin-Induced IL-8/CXCL8 in Lung Epithelial Cells

  Chen, B.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Interleukin-8 100%
  • Thrombin 96%
  • Chromatin Assembly and Disassembly 43%
  • Histone Acetyltransferases 39%
  • Histone Deacetylases 34%

• Analyze Exhaled Gas of COPD Patients ( II )

  Shih, C.

  5/1/15 → 4/30/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electronic Nose 100%
  • Chronic Obstructive Pulmonary Disease 82%
  • Gases 26%
  • Smart Materials 25%
  • Hand 23%

• Study the Bacteria Species of Pneumonia and Early Detect the Pathogen from Expired Gas by Electronic Nose

  Shih, C.

  5/1/13 → 10/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the bacteria species of pneumonia and early detect the pathogen from expired gas by electronic nose

  Shih, C.

  5/1/12 → 9/30/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Bacteria Species of Pneumonia and Early Detect the Pathogen from Expired Gas by Electronic Nose

  Shih, C.

  5/1/11 → 4/30/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Electronic Nose 100%
  • Pneumonia 35%
  • Sputum 34%
  • Air 28%
  • Medicine Chests 15%

• Investigate Pathogenic Role of Rheumatoid Arthritis, Sjogren's Syndrome, Systemic Lupus Erythematosus and Its Combined Syndromes from Post-Translational Modification of Novel Synovial Fluid and Serum Proteins---Study of 4-Hydroxy-2-Nonenal Modificatio

  Lin, C. & Chang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • rheumatoid arthritis 100%
  • lupus erythematosus 99%
  • autoantibodies 49%
  • proteins 31%
  • autoimmune diseases 29%

• The Imapct of Oxidative Stress on the Pathogenesis of COPD---An Ivestigation into Its Relationship with Abnormal Inflammation, DNA Instability, Epigenetics and Cell Metabolism

  Lee, K.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role and Mechanism of Dendritic Cell Pd-L1/Pd-L2 Dysregulation in Aberrant Inflammation of Copd

  Lee, K.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• TIGIT 在調節免疫拮抗點抑制劑抗藥性的角色(1/3)

  Feng, P.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• A Toxicological Assessment of Air Pollution in the Vicinity of a Petrochemical Complex

  Chuang, H. & Lee, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Particulate Matter 100%
  • Taiwan 54%
  • Toxicology 44%
  • Risk Assessment 38%
  • Methionine 19%

• The Role of ADAM 17 in Hypoxia-Induced CTGF Expression and Pulmonary Fibrosis (I)

  Chen, B.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• CAAT/enhancer binding protein beta訊息路徑參與thrombin誘導人類肺部上皮細胞IL-8/CXCL8表現之研究

  Chen, B.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role of SUV39H1 in Control of Inflammatory Genes and in Chronic Inflammation of Copd

  Lee, K., Feng, P. & Chuang, H.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Inflammation 60%
  • Blood Cells 33%
  • Histone Deacetylase 2 32%
  • Glucocorticoids 27%

• 樹突細胞PD-L1/PD-L2失調在COPD 異常發炎的角色及機制探討(2/3)

  Lee, K.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討PINK1於肺癌代謝鏈的調控機轉並研發可以調控PINK1活性的藥物(3/3)

  Lin, E. P.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Ultrafine Particles on Cardiopulmonary System: a Population-Based Approach

  Chuang, K. & Feng, P.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Particulate Matter 100%
  • Air Pollution 68%
  • Taiwan 34%
  • United States Environmental Protection Agency 33%
  • Organized Financing 13%

• Studies of Cxcl12 in Hypoxia-Induced Pulmonary Fibrosis

  Chen, B. & Chung, C.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Hypoxia 100%
  • Pulmonary Fibrosis 62%
  • Fibroblasts 58%
  • Lung 55%
  • Phosphatidylinositol 3-Kinases 35%

• The Effect of Endothelin-1 on Myofibroblast Transformation of Pleural Mesothelial Cells and Its Implications for Pleural and Pulmonary Fibrosis

  Chung, C. & Hsiao, G.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Myofibroblasts 100%
  • Endothelin-1 85%
  • Fibrosis 70%
  • Pulmonary Fibrosis 54%
  • Epithelial-Mesenchymal Transition 49%

• The Effect and Mechanisms of Chemotherapy in Recruit Inflammatory Cells into Tumor Microenvironment of Lung Cancer Patients

  Feng, P. & Lee, K.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Myeloid-Derived Suppressor Cells 100%
  • Neoplasms 26%
  • Tumor Microenvironment 25%
  • Lung Neoplasms 19%
  • Drug Therapy 19%

• 胸腔醫學學門規劃研究推動計畫

  Lee, K.

  1/1/21 → 12/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討缺氧環境對Yap/Taz調控胚胎肺部之分枝與型態:纖維母細胞所扮演的角色

  Lee, K.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Analyze Exhaled Gas of COPD Patients( I )

  Shih, C.

  5/1/14 → 10/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • Gases 47%
  • Electronic Nose 30%
  • Volatile Organic Compounds 27%
  • Therapeutic Irrigation 21%

• 慢性阻塞性氣喘患者呼吸道上皮細胞所釋放的介白質33（IL-33）影響血液中成纖維細胞的趨化、增殖與分化作用之機轉(1/3)

  Kuo, H.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• 樹突細胞PD-L1/PD-L2失調在COPD 異常發炎的角色及機制探討(3/3)

  Lee, K.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • inter-alpha-inhibitor 82%
  • Particulate Matter 74%
  • Inflammation 30%
  • human ITIH4 protein 25%

• Nucleic Acid Amplification as the Initial Diagnostic Test in Patients Suspected of Having Pulmonary Tuberculosis

  Chiang, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討慢性阻塞性肺病受類Toll受體活化調控長鏈非編碼核醣核酸的角色(3/3)

  Wu, S.

  8/1/21 → 7/31/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• 探討HMGB1對於DCLK1調控急性呼吸窘迫症候群之第二型肺泡上皮細胞老化之角色

  Lee, K.

  7/1/21 → 2/28/22

  Project: A - Government Institution › b - Ministry of Science and Technology

• NF-kB以及NF-kB repressing factor (NRF) 在慢性阻塞性肺疾病引發系統性發炎之角色探討(3/3)

  Lee, K.

  8/1/12 → 10/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • inter-alpha-inhibitor 82%
  • Particulate Matter 74%
  • Inflammation 30%
  • human ITIH4 protein 25%

• The Role and Mechanism of Cd155/Tigit in Mdsc/Tam Induced Nk Cell Dysfunction -A Link to Lung Cancer Resistance to Immune Checkpoint Blockade

  Feng, P.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 肺癌病人 T 細胞耗竭的調控機制

  Feng, P.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Impacts of Particulate Air Pollution on Repair and Abnormal Inflammation in Copd: the Role of Itih4 and the Regeneration Pathways

  Lee, K.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Chronic Obstructive Pulmonary Disease 100%
  • inter-alpha-inhibitor 82%
  • Particulate Matter 74%
  • Inflammation 30%
  • human ITIH4 protein 25%

• Studies on the Role of ORMDL3 in Thrombin-Induced IL-8/CXCL8 Expression and Airway Inflammation

  Chen, B.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Orosomucoid 100%
  • Thrombin 74%
  • Interleukin-8 34%
  • Transcription Factor AP-1 26%
  • Asthma 23%

• CAAT/enhancer binding protein beta訊息路徑參與thrombin誘導人類肺部上皮細胞IL-8/CXCL8表現之研究(3/3)

  Chen, B.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Studies on the Role of ORMDL3 in Thrombin-Induced IL-8/CXCL8 Expression and Airway Inflammation

  Chen, B.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Orosomucoid 100%
  • Thrombin 74%
  • Interleukin-8 34%
  • Transcription Factor AP-1 26%
  • Asthma 23%