Division of Hematology and Oncology

Research Output 1990 2019

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7 Citations (Scopus)

Presence of secretory cellular apoptosis susceptibility protein in cerebrospinal fluids of patients with intracerebral hemorrhage caused by stroke and neurotrauma

Tung, J. N., Tsao, T. Y., Chen, S. L., Tai, C. J., Shen, S. C., Cheng, Y. W. & Jiang, M. C., 2010, In : Neuroendocrinology Letters. 31, 3, p. 390-398 9 p.

Research output: Contribution to journalArticle

Cellular Apoptosis Susceptibility Protein
Matrix Metalloproteinase 2
Cerebral Hemorrhage
Cerebrospinal Fluid
Stroke
4 Citations (Scopus)

Pretreatment risk stratification for non-metastatic head and neck squamous cell carcinoma in a high-prevalence area

Hsieh, Y. Y., Mu-Hsin Chang, P., Chen, M. H., Chu, P. Y., Tzeng, C. H., Chang, S. Y., Chen, P. M. & Yang, M. H., Nov 2011, In : Journal of the Chinese Medical Association. 74, 11, p. 487-492 6 p.

Research output: Contribution to journalArticle

Medical Records
Retrospective Studies
Carcinoma, squamous cell of head and neck
9 Citations (Scopus)

Primary leptomeningeal melanoma mimicking meningitis: A case report and literature review

Hsieh, Y. Y., Yang, S. T., Li, W. H., Hu, C. J. & Wang, L. S., Apr 20 2015, In : Journal of Clinical Oncology. 33, 12, p. e57-e61

Research output: Contribution to journalArticle

Meningeal Neoplasms
Viral Meningitis
Meningitis
Melanoma
Differential Diagnosis
32 Citations (Scopus)

Pterostilbene simultaneously induced G0/G1-phase arrest and MAPK-mediated mitochondrial-derived apoptosis in human acute myeloid leukemia cell lines

Hsiao, P. C., Chou, Y. E., Tan, P., Lee, W-J., Yang, S. F., Chow, J-M., Chen, H. Y., Lin, C-H., Lee, L-M. & Chien, M-H., Aug 21 2014, In : PLoS One. 9, 8, e105342.

Research output: Contribution to journalArticle

myeloid leukemia
Cell Cycle Resting Phase
G1 Phase
Myeloid Cells
Acute Myeloid Leukemia
1 Citation (Scopus)

Quality of life assessment in Taiwanese patients with bone metastases from breast cancer receiving zoledronic acid

Chao, T. C., Chen, D. R., Chao, T. Y., Chen, S. C., Yeh, D. C., Wang, H. C., Huang, W. T., Rau, K. M., Chang, K. J., Yang, T. L., Lee, K. D., Tai, C. J., Tseng, L. M. & Hou, M. F., Dec 2013, In : Anticancer Research. 33, 12, p. 5543-5548 6 p.

Research output: Contribution to journalArticle

zoledronic acid
Quality of Life
Breast Neoplasms
Neoplasm Metastasis
Bone and Bones
9 Citations (Scopus)
Cell Cycle Resting Phase
HL-60 Cells
Quercetin
Autophagy
apoptosis

Rapid Remission of a Second Primary Kaposi’s Sarcoma With Thalidomide Treatment in a Patient Receiving Adjuvant Chemotherapy for Colon Cancer

Chow, J-M., Chou, K-F., Chen, W-Y., Lin, E-K., Chang, Y. F. & Su, Y. W., 2013, In : Journal of Medical Cases. 4, p. 466-470

Research output: Contribution to journalArticle

Thalidomide
Kaposi's Sarcoma
Adjuvant Chemotherapy
Colonic Neoplasms
Drug Therapy
8 Citations (Scopus)
Antineoplastic Combined Chemotherapy Protocols
Cholangiocarcinoma
Leucovorin
Liver Neoplasms
Fluorouracil
7 Citations (Scopus)
ErbB-2 Receptor
Salvage Therapy
Proxy
Ovarian Neoplasms
Monoclonal Antibodies
10 Citations (Scopus)
Cyclin-Dependent Kinases
Colorectal Neoplasms
Diphosphates
Deoxyribonucleosides
Ribonucleosides
9 Citations (Scopus)

RPS12 increases the invasiveness in cervical cancer activated by c-Myc and inhibited by the dietary flavonoids luteolin and quercetin

Lin, C. W., Lai, G. M., Chen, K. C., Lin, T. H., Fan, J. J., Hsu, R. L., Chou, C. M., Lin, C. M., Kandaswami, C. C., Lee, M. T. & Cheng, C. H., Dec 1 2015, In : Journal of Functional Foods. 19, p. 236-247 12 p.

Research output: Contribution to journalArticle

Luteolin
uterine cervical neoplasms
luteolin
Quercetin
Flavonoids
Tunica Intima
Heart Atria
Sarcoma
Recurrence
Manuscripts

Salvage therapy with sorafenib plus vinblastine and fluorouracil for metastatic renal cell carcinoma

Tai, C. J., 2009, In : Acta Oncologica. 48, 6, p. 931-932 2 p.

Research output: Contribution to journalArticle

Benzenesulfonates
Antineoplastic Combined Chemotherapy Protocols
Pyridines
Salvage Therapy
X Ray Computed Tomography
6 Citations (Scopus)

Serum Cellular Apoptosis Susceptibility Protein for Cancer Diagnosis

Tai, C. J., Chang, C. C., Shen, S. C., Lee, W. R. & Jiang, M. C., Jun 2011, In : Journal of Experimental and Clinical Medicine(Taiwan). 3, 3, p. 104-107 4 p.

Research output: Contribution to journalArticle

Cellular Apoptosis Susceptibility Protein
Blood Proteins
Neoplasms
Liver Neoplasms
Prostatic Neoplasms
6 Citations (Scopus)

Solanum nigrum protects against hepatic fibrosis via suppression of hyperglycemia in high-fat/ethanol diet-induced rats

Tai, C. J., Choong, C. Y., Shi, Y. C., Lin, Y. C., Wang, C-W., Lee, B. H. & Tai, C. J., Mar 1 2016, In : Molecules. 21, 3, 269.

Research output: Contribution to journalArticle

Solanum nigrum
hyperglycemia
fibrosis
diets
fats
37 Citations (Scopus)

Sorafenib induces preferential apoptotic killing of a drug- and radio-resistant Hep G2 cells through a mitochondria-dependent oxidative stress mechanism

Chiou, J. F., Tai, C. J., Wang, Y. H., Liu, T. Z., Jen, Y. M. & Shiau, C. Y., Oct 15 2009, In : Cancer Biology and Therapy. 8, 20, p. 1904-1913 10 p.

Research output: Contribution to journalArticle

Hep G2 Cells
Radio
Mitochondria
Oxidative Stress
Pharmaceutical Preparations
15 Citations (Scopus)

Statins improve outcomes of nonsurgical curative treatments in hepatocellular carcinoma patients

Wu, L. L., Hsieh, M. C., Chow, J. M., Liu, S. H., Chang, C. L. & Wu, S. Y., 2016, In : Medicine (United States). 95, 36, e4639.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Hepatocellular Carcinoma
Ethanol
Injections
Therapeutics
4 Citations (Scopus)

Stimulation of Fas/FasL-mediated apoptosis by luteolin through enhancement of histone H3 acetylation and c-Jun activation in HL-60 leukemia cells

Wang, S. W., Chen, Y. R., Chow, J. M., Chien, M. H., Yang, S. F., Wen, Y. C., Lee, W. J. & Tseng, T. H., Jan 1 2018, (Accepted/In press) In : Molecular Carcinogenesis.

Research output: Contribution to journalArticle

Luteolin
Fas Ligand Protein
HL-60 Cells
Acetylation
Histones
69 Citations (Scopus)

Sulfasalazine suppresses drug resistance and invasiveness of lung adenocarcinoma cells expressing AXL

Lay, J. D., Hong, C. C., Huang, J. S., Yang, Y. Y., Pao, C. Y., Liu, C. H., Lai, Y. P., Lai, G. M., Cheng, A. L., Su, I. J. & Chuang, S. E., Apr 15 2007, In : Cancer Research. 67, 8, p. 3878-3887 10 p.

Research output: Contribution to journalArticle

Sulfasalazine
Drug Resistance
Non-Small Cell Lung Carcinoma
Receptor Protein-Tyrosine Kinases
Doxorubicin
22 Citations (Scopus)
JNK Mitogen-Activated Protein Kinases
Extracellular Signal-Regulated MAP Kinases
apoptosis
Non-Small Cell Lung Carcinoma
cancer
22 Citations (Scopus)
Epithelial-Mesenchymal Transition
Cell Movement
Hepatocellular Carcinoma
Neoplasms
Vimentin
2 Citations (Scopus)
Complementary Therapies
Taiwan
Colorectal Neoplasms
Breast Neoplasms
Therapeutics
5 Citations (Scopus)

Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: Identification of functional disparities between azacytidine and decitabine

Hsieh, Y. Y., Huang, T. C., Lo, H. L., Jhan, J. Y., Chen, S. T. & Yang, P. M., May 10 2016, In : Oncotarget. 7, 19, p. 27363-27378 16 p.

Research output: Contribution to journalArticle

decitabine
Azacitidine
Drug Discovery
Genomics
Polypharmacology
2 Citations (Scopus)

Systematic polypharmacology and drug repurposing via an integrated L1000-based Connectivity Map database mining

Liu, T. P., Hsieh, Y. Y., Chou, C. J. & Yang, P. M., Nov 1 2018, In : Royal Society Open Science. 5, 11, 181321.

Research output: Contribution to journalArticle

Polypharmacology
Drug Repositioning
Databases
Pharmaceutical Preparations
Topoisomerase Inhibitors
1 Citation (Scopus)
Amphotericin B
Drug Therapy
Neoplasms
Ethanol
Cinnamomum
10 Citations (Scopus)

Targeting PML-RARα and oncogenic signaling pathways by Chinese herbal mixture Tien-Hsien liquid in acute promyelocytic leukemia NB4 cells

Lai, T-I., Yao, C. J., Yang, C. M., Chuang, S. E., Yan, J. L., Liu, C. Y., Chen, S. W., Yan, K. H. & Lai, G. M., 2011, In : Evidence-based Complementary and Alternative Medicine. 2011, 984154.

Research output: Contribution to journalArticle

Acute Promyelocytic Leukemia
Apoptosis
tien-hsien liquid
Cyclin B1
Cyclin A
6 Citations (Scopus)
Terminally Ill
Caregivers
Cross-Sectional Studies
Neoplasms
Therapeutics
5 Citations (Scopus)

The anti-hepatic fibrosis activity of ergosterol depended on upregulation of PPARgamma in HSC-T6 cells

Tai, C. J., Choong, C. Y., Lin, Y. C., Shi, Y. C. & Tai, C. J., Apr 1 2016, In : Food and Function. 7, 4, p. 1915-1923 9 p.

Research output: Contribution to journalArticle

Ergosterol
Hepatic Stellate Cells
liver cirrhosis
ergosterol
PPAR gamma
6 Citations (Scopus)

The bidirectional association between oral cancer and esophageal cancer: A population-based study in Taiwan over a 28-year period

Lee, K. D., Wang, T. Y., Lu, C. H., Huang, C. E. & Chen, M. C., 2017, In : Oncotarget. 8, 27, p. 44567-44578 12 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Esophageal Neoplasms
Taiwan
Population
Second Primary Neoplasms
8 Citations (Scopus)

The effect of mushroom beta-glucans from solid culture of ganoderma lucidum on inhibition of the primary tumor metastasis

Chen, S. N., Chang, C. S., Hung, M. H., Chen, S., Wang, W., Tai, C. J. & Lu, C. L., 2014, In : Evidence-based Complementary and Alternative Medicine. 2014, 252171.

Research output: Contribution to journalArticle

Reishi
beta-Glucans
Agaricales
Lewis Lung Carcinoma
Neoplasm Metastasis
8 Citations (Scopus)
Antrodia
Cytotoxicity
Cell Cycle Checkpoints
Doxorubicin
Cisplatin
9 Citations (Scopus)

The impact of pain control on physical and psychiatric functions of cancer patients: A nation-wide survey in Taiwan

Rau, K. M., Chen, J. S., Wu, H. B., Lin, S. F., Lai, M. K., Chow, J. M., Huang, M. L., Wang, C. J., Tai, C. J., Hwang, W. L., Lu, Y. C., Chan, C. H. & Hsieh, R. K., 2015, In : Japanese Journal of Clinical Oncology. 45, 11, p. 1042-1049 8 p.

Research output: Contribution to journalArticle

Taiwan
Psychiatry
Pain
Neoplasms
Ambulatory Care Facilities
15 Citations (Scopus)

The prognostic significance of nuclear CSE1L in urinary bladder urothelial carcinomas

Chang, C. C., Tai, C. J., Su, T. C., Shen, K. H., Lin, S. H., Yeh, C. M., Yeh, K. T., Lin, Y. M. & Jiang, M. C., Oct 2012, In : Annals of Diagnostic Pathology. 16, 5, p. 362-368 7 p.

Research output: Contribution to journalArticle

Urinary Bladder
Staining and Labeling
Carcinoma
Urinary Bladder Neoplasms
Cellular Apoptosis Susceptibility Protein

Thermal therapy in elderly patients with insomnia

Tai, C. J., You, Y. C. & Liu, C. F., Apr 1 2011, In : Journal of Alternative and Complementary Medicine. 17, 4, p. 291-292 2 p.

Research output: Contribution to journalArticle

Infrared Rays
Acupuncture Points
Sleep Initiation and Maintenance Disorders
Complementary Therapies
Hot Temperature
31 Citations (Scopus)

The synergistic anticancer effect of troglitazone combined with aspirin causes cell cycle arrest and apoptosis in human lung cancer cells

Yan, K. H., Yao, C. J., Chang, H. Y., Lai, G. M., Cheng, A. L. & Chuang, S. E., Mar 2010, In : Molecular Carcinogenesis. 49, 3, p. 235-246 12 p.

Research output: Contribution to journalArticle

troglitazone
Cell Cycle Checkpoints
Aspirin
Lung Neoplasms
Apoptosis
9 Citations (Scopus)

Thrombomodulin mediates the migration of cervical cancer cells through the regulation of epithelial-mesenchymal transition biomarkers

Tai, C-J., Cheng, C-W., Su, H. Y., Chen, W-Y., Wu, C. T., Lin, F-Y., Wang, C. K., Tai, C-J. & Wei, P-L., Jan 2014, In : Tumor Biology. 35, 1, p. 47-54 8 p.

Research output: Contribution to journalArticle

Thrombomodulin
Epithelial-Mesenchymal Transition
Uterine Cervical Neoplasms
Biomarkers
HeLa Cells
9 Citations (Scopus)

Thrombomodulin mediates the progression of epithelial ovarian cancer cells

Chen, L. M., Wang, W., Lee, J. C., Chiu, F. H., Wu, C. T., Tai, C. J., Wang, C. K., Tai, C. J., Huang, M. T. & Chang, Y. J., Dec 2013, In : Tumor Biology. 34, 6, p. 3743-3751 9 p.

Research output: Contribution to journalArticle

Thrombomodulin
Ovarian Neoplasms
Cell Movement
Growth
Ovarian epithelial cancer
Open Access
Phyllodes Tumor
Hemangiosarcoma
Breast Neoplasms
Thoracic Wall
Neoplasms
4 Citations (Scopus)
Propensity Score
Cholangiocarcinoma
Cohort Studies
Chemoradiotherapy
Population
7 Citations (Scopus)
JNK Mitogen-Activated Protein Kinases
HL-60 Cells
apoptosis
Cell death
Reactive Oxygen Species
13 Citations (Scopus)
Matrix Metalloproteinase 2
Glioblastoma
Modulation
Matrix Metalloproteinases
Proteins
5 Citations (Scopus)

Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts

Chien, M. H., Lee, T. H., Lee, W. J., Yeh, Y. H., Li, T. K., Wang, P. C., Chen, J. J., Chow, J. M., Lin, Y. W., Hsiao, M., Wang, S. W. & Hua, K. T., Mar 1 2017, In : Cancer Letters. 388, p. 249-261 13 p.

Research output: Contribution to journalArticle

Trichodermin
JNK Mitogen-Activated Protein Kinases
Pancreatic Neoplasms
Heterografts
DNA Damage
Diabetic Ketoacidosis
Type 1 Diabetes Mellitus
Diabetes Mellitus
Esophagogastric Junction
Therapeutics