Division of Hematology and Oncology

Research Output 1990 2019

Filter
Article
2019

Chemovirotherapeutic Treatment Using Camptothecin Enhances Oncolytic Measles Virus-Mediated Killing of Breast Cancer Cells

Tai, C. J., Liu, C. H., Pan, Y. C., Wong, S. H., Tai, C. J., Richardson, C. D. & Lin, L. T., Dec 1 2019, In : Scientific Reports. 9, 1, 6767.

Research output: Contribution to journalArticle

Open Access
Oncolytic Viruses
Camptothecin
Measles virus
Breast Neoplasms
Therapeutics

HDAC1,2 Knock-Out and HDACi Induced Cell Apoptosis in Imatinib-Resistant K562 Cells

Chen, S. H., Chow, J. M., Hsieh, Y. Y., Lin, C. Y., Hsu, K. W., Hsieh, W. S., Chi, W. M., Shabangu, B. M. & Lee, C. H., May 8 2019, In : International Journal of Molecular Sciences. 20, 9

Research output: Contribution to journalArticle

Open Access
Histone Deacetylase Inhibitors
K562 Cells
apoptosis
Cell death
inhibitors
Pituitary Neoplasms
Oncogenes
Renal Cell Carcinoma
Computer Simulation
Neoplasms
Open Access
gemcitabine
Computational Biology
Cell Cycle
Adenocarcinoma
Therapeutics
7 Citations (Scopus)
Stenotrophomonas maltophilia
Acinetobacter baumannii
Imipenem
Taiwan
Pseudomonas aeruginosa

In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells

Chen, J. C., Hsieh, Y. Y., Lo, H. L., Li, A., Chou, C. J. & Yang, P. M., Sep 9 2019, In : Biomolecules. 9, 9

Research output: Contribution to journalArticle

Open Access
Drug Resistance
Computer Simulation
Colorectal Neoplasms
Etoposide
Topoisomerase Inhibitors
Open Access
Cell Proliferation
Toll-Like Receptor 2
U937 Cells
Leukemia
Myeloid Differentiation Factor 88
Open Access
Phyllodes Tumor
Hemangiosarcoma
Breast Neoplasms
Thoracic Wall
Neoplasms
2018
2 Citations (Scopus)

A Phase I/II study of the combination of lapatinib and oral vinorelbine in HER2-positive metastatic breast cancer

Chen, T. W-W., Yeh, D-C., Chao, T-Y., Lin, C-H., Chow, L. W-C., Chang, D-Y., Hsieh, Y-Y., Huang, S-M., Cheng, A-L. & Lu, Y-S., Mar 1 2018, In : Japanese Journal of Clinical Oncology. 48, 3, p. 242-247 6 p.

Research output: Contribution to journalArticle

Breast Neoplasms
lapatinib
vinorelbine
Neutropenia
Diarrhea
7 Citations (Scopus)

Cantharidic acid induces apoptosis of human leukemic HL-60 cells via c-Jun N-terminal kinase-regulated caspase-8/-9/-3 activation pathway

Wang, S. C., Chow, J. M., Chien, M. H., Lin, C. W., Chen, H. Y., Hsiao, P. C. & Yang, S. F., Jan 1 2018, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journalArticle

Caspase 9
Caspase 8
JNK Mitogen-Activated Protein Kinases
HL-60 Cells
apoptosis
1 Citation (Scopus)

Cordycepin suppressed lipid accumulation via regulating AMPK activity and mitochondrial fusion in hepatocytes

Uen, W-C., Shi, Y-C., Choong, C-Y. & Tai, C-J., Aug 15 2018, In : Journal of Food Biochemistry. 0, 0, p. e12569

Research output: Contribution to journalArticle

2 Citations (Scopus)
Solanum nigrum
Mitochondrial Dynamics
Mouth Neoplasms
Squamous Cell Neoplasms
Cell Proliferation
2 Citations (Scopus)

Innovatively Therapeutic Strategy on Lung Cancer by Daily Drinking Antioxidative Plasmon-Induced Activated Water

Wang, C-K., Chen, H-C., Fang, S-U., Ho, C-W., Tai, C-J., Yang, C-P. & Liu, Y-C., Dec 1 2018, In : Scientific Reports. 8, 1, p. 6316 6316.

Research output: Contribution to journalArticle

Drinking
Lung Neoplasms
Water
Cisplatin
Therapeutics
Intensity-Modulated Radiotherapy
Propensity Score
Adenocarcinoma
Cohort Studies
Drug Therapy

Maspin enhances the anticancer activity of curcumin in hormone-refractory prostate cancer cells

Cheng, W. L., Huang, C. Y., Tai, C. J., Chang, Y. J. & Hung, C. S., Feb 1 2018, In : Anticancer Research. 38, 2, p. 863-870 8 p.

Research output: Contribution to journalArticle

Curcumin
Prostatic Neoplasms
Hormones
Curcuma
Androgens

Opposite regulation of CHOP and GRP78 and synergistic apoptosis induction by selenium yeast and fish oil via AMPK activation in lung adenocarcinoma cells

Kao, R. H., Lai, G. M., Chow, J. M., Liao, C. H., Zheng, Y. M., Tsai, W. L., Hsia, S., Lai, I. C., Lee, H. L., Chuang, S. E., Whang-Peng, J. & Yao, C. J., Oct 8 2018, In : Nutrients. 10, 10, 1458.

Research output: Contribution to journalArticle

AMP-activated protein kinase
AMP-Activated Protein Kinases
Fish Oils
Selenium
adenocarcinoma
2 Citations (Scopus)

Stimulation of Fas/FasL-mediated apoptosis by luteolin through enhancement of histone H3 acetylation and c-Jun activation in HL-60 leukemia cells

Wang, S. W., Chen, Y. R., Chow, J. M., Chien, M. H., Yang, S. F., Wen, Y. C., Lee, W. J. & Tseng, T. H., Jan 1 2018, (Accepted/In press) In : Molecular Carcinogenesis.

Research output: Contribution to journalArticle

Luteolin
Fas Ligand Protein
HL-60 Cells
Acetylation
Histones
1 Citation (Scopus)
Complementary Therapies
Taiwan
Colorectal Neoplasms
Breast Neoplasms
Therapeutics
1 Citation (Scopus)

Systematic polypharmacology and drug repurposing via an integrated L1000-based Connectivity Map database mining

Liu, T. P., Hsieh, Y. Y., Chou, C. J. & Yang, P. M., Nov 1 2018, In : Royal Society Open Science. 5, 11, 181321.

Research output: Contribution to journalArticle

Polypharmacology
Drug Repositioning
Databases
Pharmaceutical Preparations
Topoisomerase Inhibitors
Amphotericin B
Drug Therapy
Neoplasms
Ethanol
Cinnamomum
Propensity Score
Cholangiocarcinoma
Cohort Studies
Chemoradiotherapy
Population
Diabetic Ketoacidosis
Type 1 Diabetes Mellitus
Diabetes Mellitus
Esophagogastric Junction
Therapeutics
2017
5 Citations (Scopus)
MAP Kinase Signaling System
Non-Small Cell Lung Carcinoma
Lung Neoplasms
lissamine rhodamine B
Protein-Tyrosine Kinases
5 Citations (Scopus)
gemcitabine
Chemotherapy
Tumor Burden
Pancreatic Neoplasms
Heterografts
1 Citation (Scopus)

Cancer-related pain: A nationwide survey of patients' treatment modification and satisfaction in Taiwan

Rau, K. M., Chen, J. S., Wu, H. B., Lin, S. F., Huang, M. L., Tai, C. J., Hwang, W. L., Lu, Y. C., Wang, C. C. & Hsieh, R. K., Jan 1 2017, In : Japanese Journal of Clinical Oncology. 47, 11, p. 1060-1065 6 p.

Research output: Contribution to journalArticle

Taiwan
Pain
Pain Management
Analgesics
Outpatients

Cyproheptadine use in hepatocellular carcinoma

Hsieh, M. C., Lee, W. H., Wu, A. T. H., Chow, J. M., Chang, C. L., Yuan, K. S. P. & Wu, S. Y., 2017, In : American Journal of Cancer Research. 7, 3, p. 584-602 19 p.

Research output: Contribution to journalArticle

Cyproheptadine
Hepatocellular Carcinoma
Palliative Care
Cause of Death
Therapeutics
7 Citations (Scopus)

Danshen improves survival of patients with advanced lung cancer and targeting the relationship between macrophages and lung cancer cells

Wu, C. Y., Cherng, J. Y., Yang, Y. H., Lin, C. L., Kuan, F. C., Lin, Y. Y., Lin, Y. S., Shu, L. H., Cheng, Y. C., Liu, H. T., Lu, M. C., Lung, J., Chen, P. C., Lin, H. K., Lee, K. D. & Tsai, Y. H., 2017, In : Oncotarget. 8, 53, p. 90925-90947 23 p.

Research output: Contribution to journalArticle

Salvia miltiorrhiza
Lung Neoplasms
Macrophages
Survival
STAT3 Transcription Factor
17 Citations (Scopus)
Intensity-Modulated Radiotherapy
Chemoradiotherapy
Thorax
Mortality
Neoplasms
16 Citations (Scopus)
Esophagectomy
Chemoradiotherapy
Radiotherapy
Thorax
Confidence Intervals
11 Citations (Scopus)

Highly bioavailable silibinin nanoparticles inhibit HCV infection

Liu, C. H., Lin, C. C., Hsu, W. C., Chung, C. Y., Lin, C. C., Jassey, A., Chang, S. P., Tai, C. J., Tai, C. J., Shields, J., Richardson, C. D., Yen, M. H., Tyrrell, D. L. J. & Lin, L. T., Oct 2017, In : Gut. 66, 10, p. 1853-1861

Research output: Contribution to journalArticle

Nanoparticles
Infection
Hepatitis C
Solubility
Biological Availability
1 Citation (Scopus)

JAK2V617F influences epigenomic changes in myeloproliferative neoplasms

Chen, C. C., Chiu, C. C., Lee, K. D., Hsu, C. C., Chen, H. C., Huang, T. H. M., Hsiao, S. H. & Leu, Y. W., Dec 16 2017, In : Biochemical and Biophysical Research Communications. 494, 3-4, p. 470-476 7 p.

Research output: Contribution to journalArticle

STAT3 Transcription Factor
Epigenomics
Methylation
Chromatin
Neoplasms
8 Citations (Scopus)
Cell Cycle Resting Phase
HL-60 Cells
Quercetin
Autophagy
apoptosis
21 Citations (Scopus)
JNK Mitogen-Activated Protein Kinases
Extracellular Signal-Regulated MAP Kinases
apoptosis
Non-Small Cell Lung Carcinoma
cancer
6 Citations (Scopus)
Terminally Ill
Caregivers
Cross-Sectional Studies
Neoplasms
Therapeutics
2 Citations (Scopus)

The bidirectional association between oral cancer and esophageal cancer: A population-based study in Taiwan over a 28-year period

Lee, K. D., Wang, T. Y., Lu, C. H., Huang, C. E. & Chen, M. C., 2017, In : Oncotarget. 8, 27, p. 44567-44578 12 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Esophageal Neoplasms
Taiwan
Population
Second Primary Neoplasms
5 Citations (Scopus)
JNK Mitogen-Activated Protein Kinases
HL-60 Cells
apoptosis
Cell death
Reactive Oxygen Species
4 Citations (Scopus)

Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts

Chien, M. H., Lee, T. H., Lee, W. J., Yeh, Y. H., Li, T. K., Wang, P. C., Chen, J. J., Chow, J. M., Lin, Y. W., Hsiao, M., Wang, S. W. & Hua, K. T., Mar 1 2017, In : Cancer Letters. 388, p. 249-261 13 p.

Research output: Contribution to journalArticle

Trichodermin
JNK Mitogen-Activated Protein Kinases
Pancreatic Neoplasms
Heterografts
DNA Damage
2016
4 Citations (Scopus)
Neoplasms
Apoptosis
Lung Neoplasms
Proteins
Epithelial-Mesenchymal Transition
10 Citations (Scopus)

Activity-based and fraction-guided analysis of Phyllanthus urinaria identifies loliolide as a potent inhibitor of hepatitis C virus entry

Chung, C. Y., Liu, C. H., Burnouf, T., Wang, G. H., Chang, S. P., Jassey, A., Tai, C. J., Tai, C. J., Huang, C. J., Richardson, C. D., Yen, M. H., Lin, C. C. & Lin, L. T., Jun 1 2016, In : Antiviral Research. 130, p. 58-68 11 p.

Research output: Contribution to journalArticle

Phyllanthus
Virus Internalization
Hepacivirus
Antiviral Agents
Hepatitis C
20 Citations (Scopus)

Anti-cancer activity of Solanum nigrum (AESN) through suppression of mitochondrial function and epithelial-mesenchymal transition (EMT) in breast cancer cells

Lai, Y. J., Tai, C. J., Wang, C. W., Choong, C. Y., Lee, B. H., Shi, Y. C. & Tai, C. J., May 1 2016, In : Molecules. 21, 5, 553.

Research output: Contribution to journalArticle

Solanum nigrum
Epithelial-Mesenchymal Transition
breast
cancer
Cells
8 Citations (Scopus)

Aqueous extract of Paris polyphylla (AEPP) inhibits ovarian cancer via suppression of peroxisome proliferator-activated receptor-gamma coactivator (PGC)-1alpha

Wang, C. W., Tai, C. J., Choong, C. Y., Lin, Y. C., Lee, B. H., Shi, Y. C. & Tai, C. J., Jun 1 2016, In : Molecules. 21, 6, 727.

Research output: Contribution to journalArticle

PPAR gamma
Paris
Ovarian Neoplasms
Chemotherapy
cancer
6 Citations (Scopus)
gemcitabine
Pancreatic Neoplasms
Nausea
Vomiting
Fluorouracil
22 Citations (Scopus)

Curative-Intent Aggressive Treatment Improves Survival in Elderly Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma and High Comorbidity Index

Chen, J. H., Yen, Y. C., Yang, H. C., Liu, S. H., Yuan, S. P., Wu, L. L., Lee, F. P., Lin, K. C., Lai, M. T., Wu, C. C., Chen, T. M., Chang, C. L., Chow, J. M., Ding, Y. F. & Wu, S. Y., Apr 1 2016, In : Medicine (United States). 95, 14, e3268.

Research output: Contribution to journalArticle

Comorbidity
Survival
Neoplasms
Radiotherapy
Therapeutics
13 Citations (Scopus)
Unfolded Protein Response
Autophagy
Colorectal Neoplasms
Up-Regulation
Endoplasmic Reticulum Stress
6 Citations (Scopus)

Glucose-regulated protein 94 mediates metastasis by CCT8 and the JNK pathway in hepatocellular carcinoma

Wei, P-L., Huang, C. Y., Tai, C-J., Batzorig, U., Cheng, W. L., Hunag, M. T. & Chang, Y-J., Jun 1 2016, In : Tumor Biology. 37, 6, p. 8219-8227 9 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Hepatocellular Carcinoma
Neoplasm Metastasis
Neoplasms
Wound Healing
34 Citations (Scopus)
Apigenin
Acetylation
Cell proliferation
tumor
Histones
27 Citations (Scopus)

Lipocalin 2 prevents oral cancer metastasis through carbonic anhydrase IX inhibition and is associated with favourable prognosis

Lin, C. W., Yang, W. E., Lee, W. J., Hua, K. T., Hsieh, F. K., Hsiao, M., Chen, C. C., Chow, J. M., Chen, M. K., Yang, S. F. & Chien, M. H., Jul 1 2016, In : Carcinogenesis. 37, 7, p. 712-722 11 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Squamous Cell Carcinoma
Neoplasm Metastasis
Cell Movement
MicroRNAs
1 Citation (Scopus)

Maspin mediates the gemcitabine sensitivity of hormone-independent prostate cancer

Huang, C. Y., Chang, Y. J., Luo, S. D., Uyanga, B., Lin, F. Y., Tai, C. J. & Huang, M. T., Mar 1 2016, In : Tumor Biology. 37, 3, p. 4075-4082

Research output: Contribution to journalArticle

gemcitabine
Prostatic Neoplasms
Hormones
B-Cell Lymphoma
Apoptosis
15 Citations (Scopus)

Negative feedback regulation of AXL by miR-34a modulates apoptosis in lung cancer cells

Cho, C. Y., Huang, J. S., Shiah, S. G., Chung, S. Y., Lay, J. D., Yang, Y. Y., Lai, G. M., Cheng, A. L., Chen, L. T. & Chuang, S. E., Feb 1 2016, In : RNA. 22, 2, p. 303-315 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Lung Neoplasms
Activating Transcription Factors
Apoptosis
MAP Kinase Signaling System
16 Citations (Scopus)

Outcomes of induction chemotherapy for head and neck cancer patients a combined study of two national cohorts in Taiwan

Chen, J-H., Yen, Y-C., Liu, S. H., Yuan, S. P., Wu, L. L., Lee, F-P., Lin, K. C., Lai, M-T., Wu, C-C., Chen, T. M., Chang, C. L., Chow, J-M., Ding, Y. F., Lin, M-C. & Wu, S-Y., 2016, In : Medicine (United States). 95, 7, p. e2845

Research output: Contribution to journalArticle

Induction Chemotherapy
Head and Neck Neoplasms
Taiwan
docetaxel
Chemoradiotherapy