Division of Hematology and Oncology

Research Output 1990 2019

23 Citations (Scopus)
Chinese Traditional Medicine
Drug Therapy
Liver
Neoplasms
Confidence Intervals
7 Citations (Scopus)

Effects of symptoms and complementary and alternative medicine use on the yang deficiency pattern among breast cancer patients receiving chemotherapy

Huang, S. M., Chien, L. Y., Tai, C. J., Chen, P. H., Lien, P. J. & Tai, C. J., Apr 1 2015, In : Complementary Therapies in Medicine. 23, 2, p. 233-241 9 p.

Research output: Contribution to journalArticle

Yang Deficiency
Complementary Therapies
Meridians
Breast Neoplasms
Drug Therapy
5 Citations (Scopus)

Elimination of cancer stem-like side population in human glioblastoma cells accompanied with stemness gene suppression by Korean herbal recipe MSC500

Yao, C. J., Han, T. Y., Shih, P. H., Yi, T. Y., Lai, I. C., Chang, K. H., Lai, T-I., Chang, C. L. & Lai, G. M., Nov 19 2014, In : Integrative Cancer Therapies. 13, 6, p. 541-554 14 p.

Research output: Contribution to journalArticle

Glioblastoma
Side-Population Cells
temozolomide
Neoplastic Stem Cells
Glioma
95 Citations (Scopus)

Epidemiological characteristics and multiple risk factors of stomach cancer in Taiwan

Lee, H. H., Wu, H. Y., Chuang, Y. C., Chang, A. S., Chao, H. H., Chen, K. Y., Chen, H. K., Lai, G. M., Huang, H. H. & Chen, C. J., 1990, In : Anticancer Research. 10, 4, p. 875-882 8 p.

Research output: Contribution to journalArticle

Taiwan
Stomach Neoplasms
Meat
Stomach Diseases
Food

Erratum: Oxidative stress enhances AXL-mediated cell migration through AKT1/Rac1-dependent mechanism (Free Radical Biology and Medicine (2013) 65 (1246-1256))

Huang, J. S., Cho, C. Y., Hong, C. C., Yan, M. D., Hsieh, M-C., Lay, J. D., Lai, G. M., Ann-Lii, C. & Chuang, S. E., Feb 2014, In : Free Radical Biology and Medicine. 67, p. 416 1 p.

Research output: Contribution to journalArticle

Oxidative stress
Medicine
Free Radicals
25 Citations (Scopus)

Esophagectomy for locally advanced esophageal cancer, followed by chemoradiotherapy and adjuvant chemotherapy

Liu, H. C., Hung, S. K., Huang, C. J., Chen, C. C., Chen, M. J., Chang, C. C., Tai, C. J., Tzen, C. Y., Lu, L. H. & Chen, Y. J., Sep 14 2005, In : World Journal of Gastroenterology. 11, 34, p. 5367-5372 6 p.

Research output: Contribution to journalArticle

Esophagectomy
Chemoradiotherapy
Adjuvant Chemotherapy
Esophageal Neoplasms
Cisplatin
15 Citations (Scopus)
Unfolded Protein Response
Autophagy
Colorectal Neoplasms
Up-Regulation
Endoplasmic Reticulum Stress
6 Citations (Scopus)

FDG-PET for a thyroid MALT lymphoma

Lee, C. J., Hsu, C. H., Tai, C. J. & Lin, S-E., 2008, In : Acta Oncologica. 47, 6, p. 1165-1167 3 p.

Research output: Contribution to journalArticle

Marginal Zone B-Cell Lymphoma
Radiopharmaceuticals
Fluorodeoxyglucose F18
Thyroid Neoplasms
Positron-Emission Tomography

FDG-PET in an Eccrine Carcinoma of the Scalp

Lee, T. J., Tai, C-J., Chu, J-S. & Hsu, C-H., 2009, In : 核子醫學雜誌. 22, 1, p. 43-46 4 p.

Research output: Contribution to journalArticle

Scalp
Adenocarcinoma
Carcinoma
Occipital Lobe
Sweat Glands
1 Citation (Scopus)

FDG uptake in a rectal malignant melanoma [2]

Tai, C. J., Hsu, C. H., Chiou, J. F., Wu, C. H. & Lin, S-E., 2007, In : Acta Oncologica. 46, 7, p. 1030-1031 2 p.

Research output: Contribution to journalArticle

Anus Neoplasms
Radiopharmaceuticals
Fluorodeoxyglucose F18
Positron-Emission Tomography
Melanoma
13 Citations (Scopus)
Fluorouracil
Cisplatin
Hepatocellular Carcinoma
Cell Death
Neoplasms
14 Citations (Scopus)

Genetic analysis of haemophilia A in Taiwan

Chen, Y. C., Hu, S. H., Cheng, S. N. & Chao, T. Y., May 2010, In : Haemophilia. 16, 3, p. 538-544 7 p.

Research output: Contribution to journalArticle

Hemophilia A
Taiwan
Introns
Mutation
Factor VIII
29 Citations (Scopus)

Glucose-regulated protein 78 (GRP78) mediated the efficacy to curcumin treatment on hepatocellular carcinoma

Chang, Y. J., Tai, C. J., Kuo, L. J., Wei, P. L., Liang, H. H., Liu, T. Z., Wang, W., Tai, C. J., Ho, Y. S., Wu, C. H. & Huang, M. T., Aug 2011, In : Annals of Surgical Oncology. 18, 8, p. 2395-2403 9 p.

Research output: Contribution to journalArticle

Curcumin
Hepatocellular Carcinoma
In Situ Nick-End Labeling
Small Interfering RNA
Cell Cycle
61 Citations (Scopus)

Glucose-regulated protein 78 Is a novel contributor to acquisition of resistance to sorafenib in hepatocellular carcinoma

Chiou, J-F., Tai, C-J., Huang, M-T., Wei, P-L., Wang, Y. H., An, J., Wu, C-H., Liu, T. Z. & Chang, Y-J., Feb 2010, In : Annals of Surgical Oncology. 17, 2, p. 603-612 10 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Hep G2 Cells
sorafenib
glucose-regulated proteins
Neoplasms
7 Citations (Scopus)

Glucose-regulated protein 94 mediates metastasis by CCT8 and the JNK pathway in hepatocellular carcinoma

Wei, P-L., Huang, C. Y., Tai, C-J., Batzorig, U., Cheng, W. L., Hunag, M. T. & Chang, Y-J., Jun 1 2016, In : Tumor Biology. 37, 6, p. 8219-8227 9 p.

Research output: Contribution to journalArticle

MAP Kinase Signaling System
Hepatocellular Carcinoma
Neoplasm Metastasis
Neoplasms
Wound Healing
8 Citations (Scopus)

Glucose-regulated protein 94 modulates the therapeutic efficacy to taxane in cervical cancer cells

Tai, C. J., Wang, J. W., Su, H. Y., Tai, C. J., Wang, C. K., Wu, C. T., Lien, Y. C. & Chang, Y. J., Jan 2014, In : Tumor Biology. 35, 1, p. 403-410 8 p.

Research output: Contribution to journalArticle

Uterine Cervical Neoplasms
Therapeutics
Apoptosis
bcl-Associated Death Protein
glucose-regulated proteins
3 Citations (Scopus)

HDAC1,2 Knock-Out and HDACi Induced Cell Apoptosis in Imatinib-Resistant K562 Cells

Chen, S. H., Chow, J. M., Hsieh, Y. Y., Lin, C. Y., Hsu, K. W., Hsieh, W. S., Chi, W. M., Shabangu, B. M. & Lee, C. H., May 8 2019, In : International Journal of Molecular Sciences. 20, 9

Research output: Contribution to journalArticle

Open Access
Histone Deacetylase Inhibitors
K562 Cells
apoptosis
Cell death
inhibitors
11 Citations (Scopus)

Highly bioavailable silibinin nanoparticles inhibit HCV infection

Liu, C. H., Lin, C. C., Hsu, W. C., Chung, C. Y., Lin, C. C., Jassey, A., Chang, S. P., Tai, C. J., Tai, C. J., Shields, J., Richardson, C. D., Yen, M. H., Tyrrell, D. L. J. & Lin, L. T., Oct 2017, In : Gut. 66, 10, p. 1853-1861

Research output: Contribution to journalArticle

Nanoparticles
Infection
Hepatitis C
Solubility
Biological Availability
5 Citations (Scopus)

Highly diverse efficacy of salvage treatment regimens for relapsed or refractory peripheral T-cell lymphoma: A systematic review

Yang, Y. T., Tai, C-J., Chen, C-F., Wu, H. C., Mikhaylichenko, N., Chiu, H. T., Chen, Y-Y. & Hsu, Y-H., Oct 1 2016, In : PLoS One. 11, 10

Research output: Contribution to journalReview article

11 Citations (Scopus)

High nuclear expression of phosphorylated extracellular signal-regulated kinase in tumor cells in colorectal glands is associated with poor outcome in colorectal cancer

Tai, C. J., Lee, C. H., Chen, H. C., Wang, H. K., Jiang, M. C., Su, T. C., Shen, K. H., Lin, S. H., Yeh, C. M., Chen, C. J., Yeh, K. T. & Chang, C. C., Apr 2013, In : Annals of Diagnostic Pathology. 17, 2, p. 165-171 7 p.

Research output: Contribution to journalArticle

Extracellular Signal-Regulated MAP Kinases
Colorectal Neoplasms
Neoplasms
Adenoma
Cell Nucleus
3 Citations (Scopus)

High nuclear phosphorylated extracellular signal-regulated kinase expression associated with poor differentiation, larger tumor size, and advanced stage of breast cancer

Kuo, H. T., Hsu, H. T., Chang, C. C., Jiang, M. C., Yeh, C. M., Shen, K. H., Hsu, P. C. & Tai, C. J., 2013, In : Polish Journal of Pathology. 64, 3, p. 163-169 7 p.

Research output: Contribution to journalArticle

Extracellular Signal-Regulated MAP Kinases
Breast Neoplasms
Neoplasms
Biomarkers
Mitogen-Activated Protein Kinase 1
27 Citations (Scopus)
caspase-8
myeloid leukemia
Caspase 9
Caspase 8
Myeloid Cells
29 Citations (Scopus)
Catenins
Neoplastic Stem Cells
Mouth Neoplasms
Side-Population Cells
Apoptosis
43 Citations (Scopus)

Honokiol-induced apoptosis and autophagy in glioblastoma multiforme cells

Chang, K. H., Yan, M. D., Yao, C. J., Lin, P. C. & Lai, G. M., Nov 2013, In : Oncology Letters. 6, 5, p. 1435-1438 4 p.

Research output: Contribution to journalArticle

Autophagy
Glioblastoma
Apoptosis
lissamine rhodamine B
Cell Line
67 Citations (Scopus)
Caspases
Cytochromes c
Blood-Brain Barrier
Neuroblastoma
Mitochondria
3 Citations (Scopus)

Identification of a new peptide for fibrosarcoma tumor targeting and imaging in vivo

Wu, C. C., Lin, E. H., Lee, Y. C., Tai, C. J., Kuo, T. H., Wang, H. E., Luo, T. Y., Fu, Y. K., Chen, H. J., Sun, M. D., Wu, C. H., Wu, C. W., Leu, S. J. & Deng, W. P., 2010, In : Journal of Biomedicine and Biotechnology. 2010, 167045.

Research output: Contribution to journalArticle

Fibrosarcoma
Tumors
Bacteriophages
Imaging techniques
Peptides
33 Citations (Scopus)

Increased cellular apoptosis susceptibility (CSE1L/CAS) protein expression promotes protrusion extension and enhances migration of MCF-7 breast cancer cells

Tai, C. J., Shen, S. C., Lee, W. R., Liao, C. F., Deng, W. P., Chiou, H. Y., Hsieh, C. I., Tung, J. N., Chen, C. S., Chiou, J. F., Li, L. T., Lin, C. Y., Hsu, C. H. & Jiang, M. C., Oct 2010, In : Experimental Cell Research. 316, 17, p. 2969-2981 13 p.

Research output: Contribution to journalArticle

Cellular Apoptosis Susceptibility Protein
Tubulin
Apoptosis
Breast Neoplasms
Microtubules
2 Citations (Scopus)

Increases in Xu Zheng and Yu Zheng among patients with breast cancer receiving different anticancer drug therapies

Tai, C. J., Huang, S. M., Chien, L. Y., Tai, C. J., Tseng, L. M. & Chen, P. H., 2013, In : Evidence-based Complementary and Alternative Medicine. 2013, 392024.

Research output: Contribution to journalArticle

Yin Deficiency
Yang Deficiency
Breast Neoplasms
Drug Therapy
Therapeutics
3 Citations (Scopus)
Solanum nigrum
Mitochondrial Dynamics
Mouth Neoplasms
Squamous Cell Neoplasms
Cell Proliferation
37 Citations (Scopus)
Apigenin
Acetylation
Cell proliferation
tumor
Histones
3 Citations (Scopus)

Innovatively Therapeutic Strategy on Lung Cancer by Daily Drinking Antioxidative Plasmon-Induced Activated Water

Wang, C-K., Chen, H-C., Fang, S-U., Ho, C-W., Tai, C-J., Yang, C-P. & Liu, Y-C., Dec 1 2018, In : Scientific Reports. 8, 1, p. 6316 6316.

Research output: Contribution to journalArticle

Drinking
Lung Neoplasms
Water
Cisplatin
Therapeutics
Pituitary Neoplasms
Oncogenes
Renal Cell Carcinoma
Computer Simulation
Neoplasms
14 Citations (Scopus)
Solanum nigrum
Doxorubicin
Cisplatin
Hepatocellular Carcinoma
Drug Therapy
Open Access
gemcitabine
Computational Biology
Cell Cycle
Adenocarcinoma
Therapeutics
4 Citations (Scopus)
Intensity-Modulated Radiotherapy
Propensity Score
Adenocarcinoma
Cohort Studies
Drug Therapy

Intravenous Pamidronate in the Management of Cancer-associated Hypercalcemia: An Experience in the Taipei Veterans General Hospital

Tai, C-J., Wang, W. S., Chiou, T. J., Liu, J. H., Fan, F. S., Chen, P. M. & Yen, C. C., Sep 2000, In : New Taipei Journal of Medicine. 2, 3, p. 201-206 6 p.

Research output: Contribution to journalArticle

In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells

Chen, J. C., Hsieh, Y. Y., Lo, H. L., Li, A., Chou, C. J. & Yang, P. M., Sep 9 2019, In : Biomolecules. 9, 9

Research output: Contribution to journalArticle

Open Access
Drug Resistance
Computer Simulation
Colorectal Neoplasms
Etoposide
Topoisomerase Inhibitors
1 Citation (Scopus)

JAK2V617F influences epigenomic changes in myeloproliferative neoplasms

Chen, C. C., Chiu, C. C., Lee, K. D., Hsu, C. C., Chen, H. C., Huang, T. H. M., Hsiao, S. H. & Leu, Y. W., Dec 16 2017, In : Biochemical and Biophysical Research Communications. 494, 3-4, p. 470-476 7 p.

Research output: Contribution to journalArticle

STAT3 Transcription Factor
Epigenomics
Methylation
Chromatin
Neoplasms
20 Citations (Scopus)

Keap1-Nrf2 interaction suppresses cell motility in lung adenocarcinomas by targeting the S100P protein

Chien, M. H., Lee, W. J., Hsieh, F. K., Li, C. F., Cheng, T. Y., Wang, M. Y., Chen, J. S., Chow, J. M., Jan, Y. H., Hsiao, M., Hua, K. T. & Kuo, M. L., Oct 15 2015, In : Clinical Cancer Research. 21, 20, p. 4719-4732 14 p.

Research output: Contribution to journalArticle

Protein Transport
Cell Movement
Non-Small Cell Lung Carcinoma
Neoplasm Metastasis
Kelch-Like ECH-Associated Protein 1
31 Citations (Scopus)

Lipocalin 2 prevents oral cancer metastasis through carbonic anhydrase IX inhibition and is associated with favourable prognosis

Lin, C. W., Yang, W. E., Lee, W. J., Hua, K. T., Hsieh, F. K., Hsiao, M., Chen, C. C., Chow, J. M., Chen, M. K., Yang, S. F. & Chien, M. H., Jul 1 2016, In : Carcinogenesis. 37, 7, p. 712-722 11 p.

Research output: Contribution to journalArticle

Mouth Neoplasms
Squamous Cell Carcinoma
Neoplasm Metastasis
Cell Movement
MicroRNAs
36 Citations (Scopus)

Loss of EGFR signaling regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance

Siu, M. K., Abou-Kheir, W., Yin, J. J., Chang, Y. S., Barrett, B., Suau, F., Casey, O., Chen, W. Y., Fang, L., Hynes, P., Hsieh, Y. Y., Liu, Y. N., Huang, J. & Kelly, K., 2014, In : Oncotarget. 5, 11, p. 3770-3784 15 p.

Research output: Contribution to journalArticle

Bone Neoplasms
Protein-Tyrosine Kinases
Prostatic Neoplasms
Neoplasm Metastasis
Apoptosis Regulatory Proteins

Maspin enhances the anticancer activity of curcumin in hormone-refractory prostate cancer cells

Cheng, W. L., Huang, C. Y., Tai, C. J., Chang, Y. J. & Hung, C. S., Feb 1 2018, In : Anticancer Research. 38, 2, p. 863-870 8 p.

Research output: Contribution to journalArticle

Curcumin
Prostatic Neoplasms
Hormones
Curcuma
Androgens
2 Citations (Scopus)

Maspin mediates the gemcitabine sensitivity of hormone-independent prostate cancer

Huang, C. Y., Chang, Y. J., Luo, S. D., Uyanga, B., Lin, F. Y., Tai, C. J. & Huang, M. T., Mar 1 2016, In : Tumor Biology. 37, 3, p. 4075-4082

Research output: Contribution to journalArticle

gemcitabine
Prostatic Neoplasms
Hormones
B-Cell Lymphoma
Apoptosis
15 Citations (Scopus)

Mefloquine exerts anticancer activity in prostate cancer cells via ROS-mediated modulation of Akt, ERK, JNK and AMPK signaling

Yan, K. H., Yao, C. J., Hsiao, C. H., Lin, K. H., Lin, Y. W., Wen, Y-C., Liu, C. C., Yan, M. D., Chuang, S. E., Lai, G. M. & Lee, L. M., Oct 2013, In : Oncology Letters. 5, 5, p. 1541-1545 5 p.

Research output: Contribution to journalArticle

Mefloquine
Extracellular Signal-Regulated MAP Kinases
Adenosine Monophosphate
Protein Kinases
Reactive Oxygen Species
13 Citations (Scopus)

Mefloquine induces cell death in prostate cancer cells and provides a potential novel treatment strategy in vivo

Yan, K. H., Lin, Y. W., Hsiao, C. H., Wen, Y-C., Lin, K. H., Liu, C. C., Hsieh, M-C., Yao, C. J., Yan, M. D., Lai, G. M., Chuang, S. E. & Lee, L. M., Oct 2013, In : Oncology Letters. 5, 5, p. 1567-1571 5 p.

Research output: Contribution to journalArticle

Mefloquine
Prostatic Neoplasms
Cell Death
lissamine rhodamine B
Reactive Oxygen Species
18 Citations (Scopus)

Negative feedback regulation of AXL by miR-34a modulates apoptosis in lung cancer cells

Cho, C. Y., Huang, J. S., Shiah, S. G., Chung, S. Y., Lay, J. D., Yang, Y. Y., Lai, G. M., Cheng, A. L., Chen, L. T. & Chuang, S. E., Feb 1 2016, In : RNA. 22, 2, p. 303-315 13 p.

Research output: Contribution to journalArticle

MicroRNAs
Lung Neoplasms
Activating Transcription Factors
Apoptosis
MAP Kinase Signaling System
22 Citations (Scopus)

Nobiletin suppresses the proliferation and induces apoptosis involving MAPKs and caspase-8/-9/-3 signals in human acute myeloid leukemia cells

Hsiao, P. C., Lee, W-J., Yang, S. F., Tan, P., Chen, H. Y., Lee, L-M., Chang, J. L., Lai, G-M., Chow, J-M. & Chien, M-H., Dec 1 2014, In : Tumor Biology. 35, 12, p. 11903-11911 9 p.

Research output: Contribution to journalArticle

Caspase 9
Caspase 8
Myeloid Cells
Acute Myeloid Leukemia
Apoptosis
1 Citation (Scopus)

Opposite regulation of CHOP and GRP78 and synergistic apoptosis induction by selenium yeast and fish oil via AMPK activation in lung adenocarcinoma cells

Kao, R. H., Lai, G. M., Chow, J. M., Liao, C. H., Zheng, Y. M., Tsai, W. L., Hsia, S., Lai, I. C., Lee, H. L., Chuang, S. E., Whang-Peng, J. & Yao, C. J., Oct 8 2018, In : Nutrients. 10, 10, 1458.

Research output: Contribution to journalArticle

AMP-activated protein kinase
AMP-Activated Protein Kinases
Fish Oils
Selenium
adenocarcinoma
18 Citations (Scopus)

Outcomes of induction chemotherapy for head and neck cancer patients a combined study of two national cohorts in Taiwan

Chen, J-H., Yen, Y-C., Liu, S. H., Yuan, S. P., Wu, L. L., Lee, F-P., Lin, K. C., Lai, M-T., Wu, C-C., Chen, T. M., Chang, C. L., Chow, J-M., Ding, Y. F., Lin, M-C. & Wu, S-Y., 2016, In : Medicine (United States). 95, 7, p. e2845

Research output: Contribution to journalArticle

Induction Chemotherapy
Head and Neck Neoplasms
Taiwan
docetaxel
Chemoradiotherapy
27 Citations (Scopus)

Oxidative stress enhances Axl-mediated cell migration through an Akt1/Rac1-dependent mechanism

Huang, J. S., Cho, C. Y., Hong, C. C., Yan, M. D., Hsieh, M-C., Lay, J. D., Lai, G. M., Cheng, A. L. & Chuang, S. E., 2013, In : Free Radical Biology and Medicine. 65, p. 1246-1256 11 p.

Research output: Contribution to journalArticle

Oxidative stress
Cell Movement
Reactive Oxygen Species
Oxidative Stress
Phosphatidylinositol 3-Kinases