Division of Hematology and Oncology

Research Output 1990 2019

22 Citations (Scopus)

6-Dehydrogingerdione sensitizes human hepatoblastoma hep G2 cells to trail-induced apoptosis via reactive oxygen species-mediated increase of dr5

Chen, C. Y., Tai, C. J., Cheng, J. T., Zheng, J. J., Chen, Y. Z., Liu, T. Z., Yiin, S. J. & Chern, C. L., May 12 2010, In : Journal of Agricultural and Food Chemistry. 58, 9, p. 5604-5611 8 p.

Research output: Contribution to journalArticle

Hepatoblastoma
Hep G2 Cells
reactive oxygen species
Reactive Oxygen Species
apoptosis
13 Citations (Scopus)

A comparative study of symptoms and quality of life among patients with breast cancer receiving target, chemotherapy, or combined therapy

Huang, S. M., Tai, C-J., Lin, K. C., Tai, C-J., Tseng, L. M. & Chien, L. Y., Jul 2013, In : Cancer Nursing. 36, 4, p. 317-325 9 p.

Research output: Contribution to journalArticle

Quality of Life
Breast Neoplasms
Drug Therapy
Therapeutics
Group Psychotherapy
4 Citations (Scopus)
Neoplasms
Apoptosis
Lung Neoplasms
Proteins
Epithelial-Mesenchymal Transition
6 Citations (Scopus)
MAP Kinase Signaling System
Non-Small Cell Lung Carcinoma
Lung Neoplasms
lissamine rhodamine B
Protein-Tyrosine Kinases
12 Citations (Scopus)

Activity-based and fraction-guided analysis of Phyllanthus urinaria identifies loliolide as a potent inhibitor of hepatitis C virus entry

Chung, C. Y., Liu, C. H., Burnouf, T., Wang, G. H., Chang, S. P., Jassey, A., Tai, C. J., Tai, C. J., Huang, C. J., Richardson, C. D., Yen, M. H., Lin, C. C. & Lin, L. T., Jun 1 2016, In : Antiviral Research. 130, p. 58-68 11 p.

Research output: Contribution to journalArticle

Phyllanthus
Virus Internalization
Hepacivirus
Antiviral Agents
Hepatitis C
6 Citations (Scopus)

Adjuvant trastuzumab for 6 months is effective in patients with HER2-positive stage II or III breast cancer

Tai, C. J., Pan, C. K., Chen, C. S., Hung, C. S., Wu, C. H. & Chiou, H. Y., 2013, In : Asian Pacific Journal of Cancer Prevention. 14, 3, p. 1981-1984 4 p.

Research output: Contribution to journalArticle

Breast Neoplasms
Chills
Trastuzumab
Dizziness
Therapeutics
9 Citations (Scopus)

Alpha 7-nicotinic acetylcholine receptor mediates the sensitivity of gastric cancer cells to 5-fluorouracil

Chen, W-Y., Huang, C. Y., Cheng, W. L., Hung, C-S., Huang, M-T., Tai, C-J., Liu, Y-N., Chen, C-L. & Chang, Y-J., Jul 3 2015, (Accepted/In press) In : Tumor Biology. 36, 12, p. 9537-9544

Research output: Contribution to journalArticle

Nicotinic Receptors
Fluorouracil
Stomach Neoplasms
In Situ Nick-End Labeling
Cell Cycle
9 Citations (Scopus)

A multicenter phase II study of biweekly capecitabine in combination with oxaliplatin as first-line chemotherapy in patients with locally advanced or metastatic gastric cancer

Chao, Y., Hsieh, J. S., Yeh, H. T., Su, Y. C., Wu, C. C., Chen, J. S., Tai, C. J., Bai, L. Y., Yeh, K. H., Su, W. C. & Li, C. P., 2014, In : Cancer Chemotherapy and Pharmacology. 73, 4, p. 799-806 8 p.

Research output: Contribution to journalArticle

oxaliplatin
Chemotherapy
Stomach Neoplasms
Toxicity
Drug Therapy
21 Citations (Scopus)

Anti-cancer activity of Solanum nigrum (AESN) through suppression of mitochondrial function and epithelial-mesenchymal transition (EMT) in breast cancer cells

Lai, Y. J., Tai, C. J., Wang, C. W., Choong, C. Y., Lee, B. H., Shi, Y. C. & Tai, C. J., May 1 2016, In : Molecules. 21, 5, 553.

Research output: Contribution to journalArticle

Solanum nigrum
Epithelial-Mesenchymal Transition
breast
cancer
Cells
9 Citations (Scopus)
Camptotheca
Camptothecin
Endometrial Neoplasms
Fruit
Cisplatin
2 Citations (Scopus)

A Phase I/II study of the combination of lapatinib and oral vinorelbine in HER2-positive metastatic breast cancer

Chen, T. W-W., Yeh, D-C., Chao, T-Y., Lin, C-H., Chow, L. W-C., Chang, D-Y., Hsieh, Y-Y., Huang, S-M., Cheng, A-L. & Lu, Y-S., Mar 1 2018, In : Japanese Journal of Clinical Oncology. 48, 3, p. 242-247 6 p.

Research output: Contribution to journalArticle

Breast Neoplasms
lapatinib
vinorelbine
Neutropenia
Diarrhea
20 Citations (Scopus)
Catenins
Wnt Signaling Pathway
Colonic Neoplasms
Cell Death
Apoptosis
8 Citations (Scopus)

Aqueous extract of Paris polyphylla (AEPP) inhibits ovarian cancer via suppression of peroxisome proliferator-activated receptor-gamma coactivator (PGC)-1alpha

Wang, C. W., Tai, C. J., Choong, C. Y., Lin, Y. C., Lee, B. H., Shi, Y. C. & Tai, C. J., Jun 1 2016, In : Molecules. 21, 6, 727.

Research output: Contribution to journalArticle

PPAR gamma
Paris
Ovarian Neoplasms
Chemotherapy
cancer
15 Citations (Scopus)
docetaxel
Solanum nigrum
Autophagy
Endometrial Neoplasms
Neoplasms
37 Citations (Scopus)
docetaxel
Solanum nigrum
Autophagy
Fluorouracil
Doxorubicin
20 Citations (Scopus)
Nursing Education
Nursing Care
Catheters
Retrospective Studies
Guidelines
11 Citations (Scopus)

Aspirin antagonizes the cytotoxic effect of methotrexate in lung cancer cells

Yan, K. H., Lee, L. M., Hsieh, M-C., Yan, M. D., Yao, C. J., Chang, P. Y., Chen, T. L., Chang, H. Y., Cheng, A. L., Lai, G. M. & Chuang, S. E., Sep 2013, In : Oncology Reports. 30, 3, p. 1497-1505 9 p.

Research output: Contribution to journalArticle

Methotrexate
Aspirin
Lung Neoplasms
Tetrahydrofolate Dehydrogenase
S Phase
7 Citations (Scopus)
gemcitabine
Chemotherapy
Tumor Burden
Pancreatic Neoplasms
Heterografts
3 Citations (Scopus)

Breast MRI for monitoring images of an "adenomyoepithelioma with malignant features", before, during, and after chemotherapy

Leung, T-K., Chu, J. S., Huang, P. J., Lin, Y. H., Lee, C-M., Chen, C. S., Tai, C. J. & Wu, C. H., Nov 2010, In : Breast Journal. 16, 6, p. 652-653 2 p.

Research output: Contribution to journalArticle

Adenomyoepithelioma
Breast
Magnetic Resonance Imaging
Breast Neoplasms
Drug Therapy
2 Citations (Scopus)

Cancer-related pain: A nationwide survey of patients' treatment modification and satisfaction in Taiwan

Rau, K. M., Chen, J. S., Wu, H. B., Lin, S. F., Huang, M. L., Tai, C. J., Hwang, W. L., Lu, Y. C., Wang, C. C. & Hsieh, R. K., Jan 1 2017, In : Japanese Journal of Clinical Oncology. 47, 11, p. 1060-1065 6 p.

Research output: Contribution to journalArticle

Taiwan
Pain
Pain Management
Analgesics
Outpatients
9 Citations (Scopus)

Cantharidic acid induces apoptosis of human leukemic HL-60 cells via c-Jun N-terminal kinase-regulated caspase-8/-9/-3 activation pathway

Wang, S. C., Chow, J. M., Chien, M. H., Lin, C. W., Chen, H. Y., Hsiao, P. C. & Yang, S. F., Jan 1 2018, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journalArticle

Caspase 9
Caspase 8
JNK Mitogen-Activated Protein Kinases
HL-60 Cells
apoptosis
24 Citations (Scopus)
Rectal Neoplasms
Biopsy
Magnetic Resonance Spectroscopy
Survival Rate
Therapeutics
1 Citation (Scopus)

Chemovirotherapeutic Treatment Using Camptothecin Enhances Oncolytic Measles Virus-Mediated Killing of Breast Cancer Cells

Tai, C. J., Liu, C. H., Pan, Y. C., Wong, S. H., Tai, C. J., Richardson, C. D. & Lin, L. T., Dec 1 2019, In : Scientific Reports. 9, 1, 6767.

Research output: Contribution to journalArticle

Open Access
Oncolytic Viruses
Camptothecin
Measles virus
Breast Neoplasms
Therapeutics
11 Citations (Scopus)

Cisplatin-, Doxorubicin-, and Docetaxel-Induced Cell Death Promoted by the Aqueous Extract of Solanum nigrum in Human Ovarian Carcinoma Cells

Tai, C. J., Wang, C. W., Chen, C. L., Wang, C. K., Chang, Y. J., Jian, J. Y., Lin, C. S. & Tai, C. J., Nov 1 2015, In : Integrative Cancer Therapies. 14, 6, p. 546-555 10 p.

Research output: Contribution to journalArticle

docetaxel
Solanum nigrum
Doxorubicin
Cisplatin
Ovarian Neoplasms
17 Citations (Scopus)

Clinical-pathological correlation of K-Ras mutation and ERK phosphorylation in colorectal cancer

Tai, C. J., Chang, C. C., Jiang, M. C., Yeh, C. M., Su, T. C., Wu, P. R., Chen, C. J., Yeh, K. T., Lin, S. H. & Chen, H. C., 2012, In : Polish Journal of Pathology. 63, 2, p. 93-100 8 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Phosphorylation
Mutation
MAP Kinase Signaling System
Mutation Rate
7 Citations (Scopus)
gemcitabine
Pancreatic Neoplasms
Nausea
Vomiting
Fluorouracil
24 Citations (Scopus)

Combined Effects of ICAM-1 Single-Nucleotide Polymorphisms and Environmental Carcinogens on Oral Cancer Susceptibility and Clinicopathologic Development

Lin, C. W., Chuang, C. Y., Tang, C. H., Chang, J. L., Lee, L-M., Lee, W-J., Chow, J-M., Yang, S. F. & Chien, M-H., Sep 12 2013, In : PLoS One. 8, 9, e72940.

Research output: Contribution to journalArticle

Environmental Carcinogens
Mouth Neoplasms
carcinogens
Intercellular Adhesion Molecule-1
Polymorphism
8 Citations (Scopus)
Hepatocellular Carcinoma
Tomography
PubMed
Libraries
Therapeutics
1 Citation (Scopus)

Cordycepin suppressed lipid accumulation via regulating AMPK activity and mitochondrial fusion in hepatocytes

Uen, W-C., Shi, Y-C., Choong, C-Y. & Tai, C-J., Aug 15 2018, In : Journal of Food Biochemistry. 0, 0, p. e12569

Research output: Contribution to journalArticle

decitabine
Azacitidine
Drug Discovery
Genomics
Medicine
2 Citations (Scopus)

Correction: Loss of EGFR signaling-regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance [Oncotarget. 5, (2014), 3770-3784]doi 10.18632/oncotarget.1994

Siu, M. K., Abou-Kheir, W., Yin, J. J., Chang, Y. S., Barrett, B., Suau, F., Casey, O., Chen, W. Y., Fang, L., Hynes, P., Hsieh, Y. Y., Liu, Y. N., Huang, J. & Kelly, K., Aug 17 2018, In : Oncotarget. 9, 64, p. 32403 1 p.

Research output: Contribution to journalComment/debate

Bone Neoplasms
Protein-Tyrosine Kinases
Prostatic Neoplasms
Medicine
Neoplasm Metastasis
2 Citations (Scopus)

Correlation of idiopathic thrombocytopenic purpura (ITP) with anti-microsomal antibody [2]

Tai, C. J., Jun 2005, In : European Journal of Haematology. 74, 6, p. 538-539 2 p.

Research output: Contribution to journalArticle

Idiopathic Thrombocytopenic Purpura
Microsomes
Platelet Count
Autoantibodies
Anti-Idiotypic Antibodies
13 Citations (Scopus)

Correlations between cytoplasmic CSE1L in neoplastic colorectal glands and depth of tumor penetration and cancer stage

Tai, C. J., Su, T. C., Jiang, M. C., Chen, H. C., Shen, S. C., Lee, W. R., Liao, C. F., Chen, Y. C., Lin, S. H., Li, L. T., Shen, K. H., Yeh, C. M., Yeh, K. T., Lee, C. H., Shih, H. Y. & Chang, C. C., Jan 31 2013, In : Journal of Translational Medicine. 11, 1, 29.

Research output: Contribution to journalArticle

Tumors
Cells
Colorectal Neoplasms
Cellular Apoptosis Susceptibility Protein
Neoplasm Metastasis
Luteolin
uterine cervical neoplasms
luteolin
Quercetin
Flavonoids
26 Citations (Scopus)

CSE1L, a novel microvesicle membrane protein, mediates Ras-triggered microvesicle generation and metastasis of tumor cells

Liao, C. F., Lin, S. H., Chen, H. C., Tai, C. J., Chang, C. C., Li, L. T., Yeh, C. M., Yeh, K. T., Chen, Y. C., Hsu, T. H., Shen, S. C., Lee, W. R., Chiou, J. F., Luo, S. F. & Jiang, M. C., 2012, In : Molecular Medicine. 18, 9, p. 1269-1280 12 p.

Research output: Contribution to journalArticle

Chromosome Segregation
Chromosomes, Human, Pair 1
Membrane Proteins
Neoplasm Metastasis
Neoplasms
12 Citations (Scopus)

CSE1L modulates ras-induced cancer cell invasion: Correlation of K-ras mutation and CSE1L expression in colorectal cancer progression

Jiang, M. C., Yeh, C. M., Tai, C. J., Chen, H. C., Lin, S. H., Su, T. C., Shen, S. C., Lee, W. R., Liao, C. F., Li, L. T., Lee, C. H., Chen, Y. C., Yeh, K. T. & Chang, C. C., Sep 2013, In : American Journal of Surgery. 206, 3, p. 418-427 10 p.

Research output: Contribution to journalArticle

Chromosome Segregation
Chromosomes, Human, Pair 1
Colorectal Neoplasms
Mutation
Neoplasms
24 Citations (Scopus)

Curative-Intent Aggressive Treatment Improves Survival in Elderly Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma and High Comorbidity Index

Chen, J. H., Yen, Y. C., Yang, H. C., Liu, S. H., Yuan, S. P., Wu, L. L., Lee, F. P., Lin, K. C., Lai, M. T., Wu, C. C., Chen, T. M., Chang, C. L., Chow, J. M., Ding, Y. F. & Wu, S. Y., Apr 1 2016, In : Medicine (United States). 95, 14, e3268.

Research output: Contribution to journalArticle

Comorbidity
Survival
Neoplasms
Radiotherapy
Therapeutics

Cyproheptadine use in hepatocellular carcinoma

Hsieh, M. C., Lee, W. H., Wu, A. T. H., Chow, J. M., Chang, C. L., Yuan, K. S. P. & Wu, S. Y., 2017, In : American Journal of Cancer Research. 7, 3, p. 584-602 19 p.

Research output: Contribution to journalArticle

Cyproheptadine
Hepatocellular Carcinoma
Palliative Care
Cause of Death
Therapeutics
10 Citations (Scopus)

Danshen improves survival of patients with advanced lung cancer and targeting the relationship between macrophages and lung cancer cells

Wu, C. Y., Cherng, J. Y., Yang, Y. H., Lin, C. L., Kuan, F. C., Lin, Y. Y., Lin, Y. S., Shu, L. H., Cheng, Y. C., Liu, H. T., Lu, M. C., Lung, J., Chen, P. C., Lin, H. K., Lee, K. D. & Tsai, Y. H., 2017, In : Oncotarget. 8, 53, p. 90925-90947 23 p.

Research output: Contribution to journalArticle

Salvia miltiorrhiza
Lung Neoplasms
Macrophages
Survival
STAT3 Transcription Factor

Deep Venous Thrombosis and Pulmonary Embolism in Pancreatic Cancer

王智慧(Zhi-Hui W, 張君照(Chung-Chao C & 戴承正(Cheng-Jeng T, 2011, In : 台灣癌症醫學雜誌. 27, 4, p. 171-176 6 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Pulmonary Embolism
Venous Thrombosis
Survival Rate
Thromboembolism
10 Citations (Scopus)

Differential distributions of CSE1L/CAS and E-cadherin in the polarized and non-polarized epithelial glands of neoplastic colorectal epithelium

Uen, W. C., Tai, C-J., Shen, S-C., Lee, W-R., Tsao, T. Y., Deng, W-P., Chiou, H-Y., Hsu, C-H., Hsieh, C. I., Liao, C. F. & Jiang, M. C., Oct 2010, In : Journal of Molecular Histology. 41, 4-5, p. 259-266 8 p.

Research output: Contribution to journalArticle

Cadherins
Epithelium
Epithelial Cells
Staining and Labeling
Cell Polarity
5 Citations (Scopus)

Differential effect of high dietary fat intakes on haemorheological parameters in rats

Tai, C. J., Chen, C. H., Chen, H. H. & Liang, H. J., Apr 2010, In : British Journal of Nutrition. 103, 7, p. 977-983 7 p.

Research output: Contribution to journalArticle

Trans Fatty Acids
Dietary Fats
High Fat Diet
Unsaturated Fatty Acids
Oils
8 Citations (Scopus)

Distribution of lysosome-associated membrane proteins-1 and-2, and cathepsin D in eosinophilic granular bodies: Possible relationship to cyst development in pilocytic astrocytomas

Tung, J. N., Tsao, T. Y., Tai, C. J., Yeh, K. T., Cheng, Y. W. & Jiang, M. C., 2010, In : Journal of International Medical Research. 38, 4, p. 1354-1364 11 p.

Research output: Contribution to journalArticle

Lysosome-Associated Membrane Glycoproteins
Cathepsin D
Astrocytoma
Cysts
Cyst Fluid
22 Citations (Scopus)
Intensity-Modulated Radiotherapy
Chemoradiotherapy
Thorax
Mortality
Neoplasms
9 Citations (Scopus)

Early viral entry assays for the identification and evaluation of antiviral compounds

Tai, C. J., Li, C. L., Tai, C. J., Wang, C. K. & Lin, L. T., Oct 29 2015, In : Journal of Visualized Experiments. 2015, 104, e53124.

Research output: Contribution to journalArticle

Antiviral agents
Antiviral Agents
Assays
Virus Inactivation
Viruses
2 Citations (Scopus)

Editor's quiz: GI Snapshot.. Multiple sessile polypoid lesions in the stomach

Tiong, C., Tai, C-J., Chen, W-Y., Chang, C-C. & Suk, F-M., Dec 2007, In : Gut. 56, 12, p. 1754

Research output: Contribution to journalArticle

Extramedullary Hematopoiesis
Stomach Diseases
Polyps
Gastric Mucosa
Stomach
15 Citations (Scopus)
Breast Neoplasms
Drug Therapy
Leukocyte Count
Teaching Hospitals
Hemoglobins
19 Citations (Scopus)
Esophagectomy
Chemoradiotherapy
Radiotherapy
Thorax
Confidence Intervals
23 Citations (Scopus)
Chinese Traditional Medicine
Drug Therapy
Liver
Neoplasms
Confidence Intervals