Division of Hematology and Oncology

Research Output 1990 2019

2019
1 Citation (Scopus)

Chemovirotherapeutic Treatment Using Camptothecin Enhances Oncolytic Measles Virus-Mediated Killing of Breast Cancer Cells

Tai, C. J., Liu, C. H., Pan, Y. C., Wong, S. H., Tai, C. J., Richardson, C. D. & Lin, L. T., Dec 1 2019, In : Scientific Reports. 9, 1, 6767.

Research output: Contribution to journal › Article

Open Access
Oncolytic Viruses
Camptothecin
Measles virus
Breast Neoplasms
Therapeutics
2 Citations (Scopus)

HDAC1,2 Knock-Out and HDACi Induced Cell Apoptosis in Imatinib-Resistant K562 Cells

Chen, S. H., Chow, J. M., Hsieh, Y. Y., Lin, C. Y., Hsu, K. W., Hsieh, W. S., Chi, W. M., Shabangu, B. M. & Lee, C. H., May 8 2019, In : International Journal of Molecular Sciences. 20, 9

Research output: Contribution to journal › Article

Open Access
Histone Deacetylase Inhibitors
K562 Cells
apoptosis
Cell death
inhibitors

In silico repurposing the Rac1 inhibitor NSC23766 for treating PTTG1-high expressing clear cell renal carcinoma

Hsieh, Y. Y., Liu, T. P. & Yang, P. M., Jan 1 2019, In : Pathology Research and Practice.

Research output: Contribution to journal › Article

Pituitary Neoplasms
Oncogenes
Renal Cell Carcinoma
Computer Simulation
Neoplasms

Integration of Bioinformatics Resources Reveals the Therapeutic Benefits of Gemcitabine and Cell Cycle Intervention in SMAD4-Deleted Pancreatic Ductal Adenocarcinoma

Hsieh, Y. Y., Liu, T. P., Chou, C. J., Chen, H. Y., Lee, K. H. & Yang, P. M., Sep 28 2019, In : Genes. 10, 10

Research output: Contribution to journal › Article

Open Access
gemcitabine
Computational Biology
Cell Cycle
Adenocarcinoma
Therapeutics

In Vitro and In Silico Mechanistic Insights into miR-21-5p-Mediated Topoisomerase Drug Resistance in Human Colorectal Cancer Cells

Chen, J. C., Hsieh, Y. Y., Lo, H. L., Li, A., Chou, C. J. & Yang, P. M., Sep 9 2019, In : Biomolecules. 9, 9

Research output: Contribution to journal › Article

Open Access
Drug Resistance
Computer Simulation
Colorectal Neoplasms
Etoposide
Topoisomerase Inhibitors

Pardaxin Promoted Differentiation and Maturation of Leukemic Cells via Regulating TLR2/MyD88 Signal against Cell Proliferation

Uen, W. C., Choong, C. Y., Tai, C. J. & Tai, C. J., Jan 1 2019, In : Evidence-based Complementary and Alternative Medicine. 2019, 7035087.

Research output: Contribution to journal › Article

Open Access
Cell Proliferation
Toll-Like Receptor 2
U937 Cells
Leukemia
Myeloid Differentiation Factor 88

Transcatheter arterial chemoembolization improves the resectability of malignant breast phyllodes tumor with angiosarcoma component: A case report

Kuo, C. Y., Lin, S. H., Lee, K. D., Cheng, S. J., Chu, J. S. & Tu, S. H., Jul 27 2019, In : BMC Surgery. 19, 1, 100.

Research output: Contribution to journal › Article

Open Access
Phyllodes Tumor
Hemangiosarcoma
Breast Neoplasms
Thoracic Wall
Neoplasms
2018
2 Citations (Scopus)

A Phase I/II study of the combination of lapatinib and oral vinorelbine in HER2-positive metastatic breast cancer

Chen, T. W-W., Yeh, D-C., Chao, T-Y., Lin, C-H., Chow, L. W-C., Chang, D-Y., Hsieh, Y-Y., Huang, S-M., Cheng, A-L. & Lu, Y-S., Mar 1 2018, In : Japanese Journal of Clinical Oncology. 48, 3, p. 242-247 6 p.

Research output: Contribution to journal › Article

Breast Neoplasms
lapatinib
vinorelbine
Neutropenia
Diarrhea
9 Citations (Scopus)

Cantharidic acid induces apoptosis of human leukemic HL-60 cells via c-Jun N-terminal kinase-regulated caspase-8/-9/-3 activation pathway

Wang, S. C., Chow, J. M., Chien, M. H., Lin, C. W., Chen, H. Y., Hsiao, P. C. & Yang, S. F., Jan 1 2018, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journal › Article

Caspase 9
Caspase 8
JNK Mitogen-Activated Protein Kinases
HL-60 Cells
apoptosis
1 Citation (Scopus)

Cordycepin suppressed lipid accumulation via regulating AMPK activity and mitochondrial fusion in hepatocytes

Uen, W-C., Shi, Y-C., Choong, C-Y. & Tai, C-J., Aug 15 2018, In : Journal of Food Biochemistry. 0, 0, p. e12569

Research output: Contribution to journal › Article

2 Citations (Scopus)

Correction: Loss of EGFR signaling-regulated miR-203 promotes prostate cancer bone metastasis and tyrosine kinase inhibitors resistance [Oncotarget. 5, (2014), 3770-3784]doi 10.18632/oncotarget.1994

Siu, M. K., Abou-Kheir, W., Yin, J. J., Chang, Y. S., Barrett, B., Suau, F., Casey, O., Chen, W. Y., Fang, L., Hynes, P., Hsieh, Y. Y., Liu, Y. N., Huang, J. & Kelly, K., Aug 17 2018, In : Oncotarget. 9, 64, p. 32403 1 p.

Research output: Contribution to journal › Comment/debate

Bone Neoplasms
Protein-Tyrosine Kinases
Prostatic Neoplasms
Medicine
Neoplasm Metastasis
3 Citations (Scopus)

Inhibition of aqueous extracts of Solanum nigrum (AESN) on oral cancer through regulation of mitochondrial fission

Uen, W. C., Lee, B. H., Shi, Y. C., Wu, S. C., Tai, C. J. & Tai, C. J., 2018, In : Journal of Traditional and Complementary Medicine.

Research output: Contribution to journal › Article

Solanum nigrum
Mitochondrial Dynamics
Mouth Neoplasms
Squamous Cell Neoplasms
Cell Proliferation
3 Citations (Scopus)

Innovatively Therapeutic Strategy on Lung Cancer by Daily Drinking Antioxidative Plasmon-Induced Activated Water

Wang, C-K., Chen, H-C., Fang, S-U., Ho, C-W., Tai, C-J., Yang, C-P. & Liu, Y-C., Dec 1 2018, In : Scientific Reports. 8, 1, p. 6316 6316.

Research output: Contribution to journal › Article

Drinking
Lung Neoplasms
Water
Cisplatin
Therapeutics
3 Citations (Scopus)

Intensity-modulated radiotherapy with systemic chemotherapy improves survival in patients with nonmetastatic unresectable pancreatic adenocarcinoma: A propensity score-matched, nationwide, population-based cohort study

Lin, Y. K., Hsieh, M. C., Chang, C. L., Chow, J. M., Yuan, K. S. P., Wu, A. T. H. & Wu, S. Y., Nov 1 2018, In : Radiotherapy and Oncology. 129, 2, p. 326-332 7 p.

Research output: Contribution to journal › Article

Intensity-Modulated Radiotherapy
Propensity Score
Adenocarcinoma
Cohort Studies
Drug Therapy

Maspin enhances the anticancer activity of curcumin in hormone-refractory prostate cancer cells

Cheng, W. L., Huang, C. Y., Tai, C. J., Chang, Y. J. & Hung, C. S., Feb 1 2018, In : Anticancer Research. 38, 2, p. 863-870 8 p.

Research output: Contribution to journal › Article

Curcumin
Prostatic Neoplasms
Hormones
Curcuma
Androgens
1 Citation (Scopus)

Opposite regulation of CHOP and GRP78 and synergistic apoptosis induction by selenium yeast and fish oil via AMPK activation in lung adenocarcinoma cells

Kao, R. H., Lai, G. M., Chow, J. M., Liao, C. H., Zheng, Y. M., Tsai, W. L., Hsia, S., Lai, I. C., Lee, H. L., Chuang, S. E., Whang-Peng, J. & Yao, C. J., Oct 8 2018, In : Nutrients. 10, 10, 1458.

Research output: Contribution to journal › Article

AMP-activated protein kinase
AMP-Activated Protein Kinases
Fish Oils
Selenium
adenocarcinoma
4 Citations (Scopus)

Stimulation of Fas/FasL-mediated apoptosis by luteolin through enhancement of histone H3 acetylation and c-Jun activation in HL-60 leukemia cells

Wang, S. W., Chen, Y. R., Chow, J. M., Chien, M. H., Yang, S. F., Wen, Y. C., Lee, W. J. & Tseng, T. H., Jan 1 2018, (Accepted/In press) In : Molecular Carcinogenesis.

Research output: Contribution to journal › Article

Luteolin
Fas Ligand Protein
HL-60 Cells
Acetylation
Histones
2 Citations (Scopus)

Symptom severity, symptom interference and use of complementary and alternative medicine among survivors of colorectal and breast cancer after curative treatment in Taiwan

Wu, H. J., Tai, C. J., Tai, C. J. & Chien, L. Y., Jan 1 2018, (Accepted/In press) In : European Journal of Cancer Care. e12925.

Research output: Contribution to journal › Article

Complementary Therapies
Taiwan
Colorectal Neoplasms
Breast Neoplasms
Therapeutics
2 Citations (Scopus)

Systematic polypharmacology and drug repurposing via an integrated L1000-based Connectivity Map database mining

Liu, T. P., Hsieh, Y. Y., Chou, C. J. & Yang, P. M., Nov 1 2018, In : Royal Society Open Science. 5, 11, 181321.

Research output: Contribution to journal › Article

Polypharmacology
Drug Repositioning
Databases
Pharmaceutical Preparations
Topoisomerase Inhibitors
1 Citation (Scopus)

Taiwanofungus camphoratus combined with amphotericin b for metastatic cancer patients unresponsive to or unwilling to undergo chemotherapy: A pilot study

Tai, C. J., Shi, Y. C., Tai, C. J., Kuo, L. J., Chen, R. J., Chang, Y. J., Tzao, C., Wu, C. H., Chang, C. C., Chiou, H. Y. & Su, C. H., Dec 1 2018, In : Alternative Therapies in Health and Medicine. 24, 12

Research output: Contribution to journal › Article

Amphotericin B
Drug Therapy
Neoplasms
Ethanol
Cinnamomum
3 Citations (Scopus)

Treatment outcomes for unresectable intrahepatic cholangiocarcinoma: Nationwide, population-based, cohort study based on propensity score matching with the Mahalanobis metric

Chang, W. W., Hsiao, P. K., Qin, L., Chang, C. L., Chow, J. M. & Wu, S. Y., Jan 1 2018, (Accepted/In press) In : Radiotherapy and Oncology. p. 1-9

Research output: Contribution to journal › Article

Propensity Score
Cholangiocarcinoma
Cohort Studies
Chemoradiotherapy
Population

Type 1 diabetes mellitus with diabetic ketoacidosis after immune checkpoint inhibitor therapy

Chuang, P. Y., Chao, T-Y. & Hsieh, Y-Y., Dec 2018, In : Journal of Cancer Research and Practice. p. 153-155

Research output: Contribution to journal › Article

Diabetic Ketoacidosis
Type 1 Diabetes Mellitus
Diabetes Mellitus
Esophagogastric Junction
Therapeutics
2017
6 Citations (Scopus)

Active fraction (HS7) from Taiwanofungus camphoratus inhibits AKT-mTOR, ERK and STAT3 pathways and induces CDK inhibitors in CL1-0 human lung cancer cells

Lai, I. C., Lai, G. M., Chow, J. M., Lee, H. L., Yeh, C. F., Li, C. H., Yan, J. L., Chuang, S. E., Whang-Peng, J., Bai, K. J. & Yao, C. J., Nov 15 2017, In : Chinese Medicine (United Kingdom). 12, 1, 33.

Research output: Contribution to journal › Article

MAP Kinase Signaling System
Non-Small Cell Lung Carcinoma
Lung Neoplasms
lissamine rhodamine B
Protein-Tyrosine Kinases
7 Citations (Scopus)

Bevacizumab and cetuximab with conventional chemotherapy reduced pancreatic tumor weight in mouse pancreatic cancer xenografts

Tai, C. J., Wang, H., Wang, C. K., Tai, C. J., Huang, M. T., Wu, C. H., Chen, R. J., Kuo, L. J., Wei, P. L., Chang, Y. J., Chang, C. C., Chiou, H. Y. & Wu, C. J., May 1 2017, In : Clinical and Experimental Medicine. 17, 2, p. 141-150 10 p.

Research output: Contribution to journal › Article

gemcitabine
Chemotherapy
Tumor Burden
Pancreatic Neoplasms
Heterografts
2 Citations (Scopus)

Cancer-related pain: A nationwide survey of patients' treatment modification and satisfaction in Taiwan

Rau, K. M., Chen, J. S., Wu, H. B., Lin, S. F., Huang, M. L., Tai, C. J., Hwang, W. L., Lu, Y. C., Wang, C. C. & Hsieh, R. K., Jan 1 2017, In : Japanese Journal of Clinical Oncology. 47, 11, p. 1060-1065 6 p.

Research output: Contribution to journal › Article

Taiwan
Pain
Pain Management
Analgesics
Outpatients

Corrigendum to “RPS12 increases the invasiveness in cervical cancer activated by c-Myc and inhibited by the dietary flavonoids luteolin and quercetin” [J. Funct. Foods (2015) 19PA (236–247)] (S1756464615004478)(10.1016/j.jff.2015.09.030)

Lin, C-W., Lai, G-M., Chen, K-C., Lin, T. H., Fan, J. J., Hsu, R. L., Chou, C-M., Lin, C-M., Kandaswami, C. C., Lee, M. T. & Cheng, C-H., Feb 1 2017, In : Journal of Functional Foods. 29, p. 303 1 p.

Research output: Contribution to journal › Comment/debate

Luteolin
uterine cervical neoplasms
luteolin
Quercetin
Flavonoids

Cyproheptadine use in hepatocellular carcinoma

Hsieh, M. C., Lee, W. H., Wu, A. T. H., Chow, J. M., Chang, C. L., Yuan, K. S. P. & Wu, S. Y., 2017, In : American Journal of Cancer Research. 7, 3, p. 584-602 19 p.

Research output: Contribution to journal › Article

Cyproheptadine
Hepatocellular Carcinoma
Palliative Care
Cause of Death
Therapeutics
10 Citations (Scopus)

Danshen improves survival of patients with advanced lung cancer and targeting the relationship between macrophages and lung cancer cells

Wu, C. Y., Cherng, J. Y., Yang, Y. H., Lin, C. L., Kuan, F. C., Lin, Y. Y., Lin, Y. S., Shu, L. H., Cheng, Y. C., Liu, H. T., Lu, M. C., Lung, J., Chen, P. C., Lin, H. K., Lee, K. D. & Tsai, Y. H., 2017, In : Oncotarget. 8, 53, p. 90925-90947 23 p.

Research output: Contribution to journal › Article

Salvia miltiorrhiza
Lung Neoplasms
Macrophages
Survival
STAT3 Transcription Factor
23 Citations (Scopus)

Dose escalation intensity-modulated radiotherapy-based concurrent chemoradiotherapy is effective for advanced-stage thoracic esophageal squamous cell carcinoma

Chang, C. L., Tsai, H. C., Lin, W. C., Chang, J. H., Hsu, H. L., Chow, J. M., Yuan, K. S. P., Wu, A. T. H. & Wu, S. Y., 2017, (Accepted/In press) In : Radiotherapy and Oncology.

Research output: Contribution to journal › Article

Intensity-Modulated Radiotherapy
Chemoradiotherapy
Thorax
Mortality
Neoplasms
19 Citations (Scopus)

Effectiveness of esophagectomy in patients with thoracic esophageal squamous cell carcinoma receiving definitive radiotherapy or concurrent chemoradiotherapy through intensity-modulated radiation therapy techniques

Yen, Y-C., Chang, J. H., Lin, W. C., Chiou, J. F., Chang, Y. C., Chang, C. L., Hsu, H. L., Chow, J. M., Yuan, K. S. P., Wu, A. T. H. & Wu, S. Y., 2017, (Accepted/In press) In : Cancer.

Research output: Contribution to journal › Article

Esophagectomy
Chemoradiotherapy
Radiotherapy
Thorax
Confidence Intervals
11 Citations (Scopus)

Highly bioavailable silibinin nanoparticles inhibit HCV infection

Liu, C. H., Lin, C. C., Hsu, W. C., Chung, C. Y., Lin, C. C., Jassey, A., Chang, S. P., Tai, C. J., Tai, C. J., Shields, J., Richardson, C. D., Yen, M. H., Tyrrell, D. L. J. & Lin, L. T., Oct 2017, In : Gut. 66, 10, p. 1853-1861

Research output: Contribution to journal › Article

Nanoparticles
Infection
Hepatitis C
Solubility
Biological Availability
1 Citation (Scopus)

JAK2V617F influences epigenomic changes in myeloproliferative neoplasms

Chen, C. C., Chiu, C. C., Lee, K. D., Hsu, C. C., Chen, H. C., Huang, T. H. M., Hsiao, S. H. & Leu, Y. W., Dec 16 2017, In : Biochemical and Biophysical Research Communications. 494, 3-4, p. 470-476 7 p.

Research output: Contribution to journal › Article

STAT3 Transcription Factor
Epigenomics
Methylation
Chromatin
Neoplasms
9 Citations (Scopus)

Quercetin simultaneously induces G0/G1-phase arrest and caspase-mediated crosstalk between apoptosis and autophagy in human leukemia HL-60 cells

Chang, J. L., Chow, J. M., Chang, J. H., Wen, Y-C., Lin, Y. W., Yang, S. F., Lee, W. J. & Chien, M. H., 2017, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journal › Article

Cell Cycle Resting Phase
HL-60 Cells
Quercetin
Autophagy
apoptosis
22 Citations (Scopus)

Suppression of reactive oxygen species-mediated ERK and JNK activation sensitizes dihydromyricetin-induced mitochondrial apoptosis in human non-small cell lung cancer

Kao, S. J., Lee, W. J., Chang, J. H., Chow, J. M., Chung, C. L., Hung, W. Y. & Chien, M. H., Apr 1 2017, In : Environmental Toxicology. 32, 4, p. 1426-1438

Research output: Contribution to journal › Article

JNK Mitogen-Activated Protein Kinases
Extracellular Signal-Regulated MAP Kinases
apoptosis
Non-Small Cell Lung Carcinoma
cancer
6 Citations (Scopus)

Terminally Ill Taiwanese Cancer Patients’ and Family Caregivers’ Agreement on Patterns of Life-Sustaining Treatment Preferences Is Poor to Fair and Declines Over a Decade: Results From Two Independent Cross-Sectional Studies

Liu, T. W., Wen, F. H., Wang, C. H., Hong, R. L., Chow, J. M., Chen, J. S., Chiu, C. F. & Tang, S. T., Jul 1 2017, In : Journal of Pain and Symptom Management. 54, 1, p. 35-45.e4

Research output: Contribution to journal › Article

Terminally Ill
Caregivers
Cross-Sectional Studies
Neoplasms
Therapeutics
6 Citations (Scopus)

The bidirectional association between oral cancer and esophageal cancer: A population-based study in Taiwan over a 28-year period

Lee, K. D., Wang, T. Y., Lu, C. H., Huang, C. E. & Chen, M. C., 2017, In : Oncotarget. 8, 27, p. 44567-44578 12 p.

Research output: Contribution to journal › Article

Mouth Neoplasms
Esophageal Neoplasms
Taiwan
Population
Second Primary Neoplasms
7 Citations (Scopus)

Tricetin induces apoptosis of human leukemic HL-60 cells through a reactive oxygen species-mediated c-jun N-terminal kinase activation pathway

Chien, M. H., Chow, J. M., Lee, W. J., Chen, H. Y., Tan, P., Wen, Y. C., Lin, Y. W., Hsiao, P. C. & Yang, S. F., Aug 1 2017, In : International Journal of Molecular Sciences. 18, 8, 1667.

Research output: Contribution to journal › Article

JNK Mitogen-Activated Protein Kinases
HL-60 Cells
apoptosis
Cell death
Reactive Oxygen Species
5 Citations (Scopus)

Trichodermin induces c-Jun N-terminal kinase-dependent apoptosis caused by mitotic arrest and DNA damage in human p53-mutated pancreatic cancer cells and xenografts

Chien, M. H., Lee, T. H., Lee, W. J., Yeh, Y. H., Li, T. K., Wang, P. C., Chen, J. J., Chow, J. M., Lin, Y. W., Hsiao, M., Wang, S. W. & Hua, K. T., Mar 1 2017, In : Cancer Letters. 388, p. 249-261 13 p.

Research output: Contribution to journal › Article

Trichodermin
JNK Mitogen-Activated Protein Kinases
Pancreatic Neoplasms
Heterografts
DNA Damage
2016
4 Citations (Scopus)

Activation of p53/miR-34a tumor suppressor axis by Chinese herbal formula JP-1 in A549 lung adenocarcinoma cells

Yao, C. J., Chow, J. M., Lin, P. C., Hu, T. S., Kuo, H. C., Huang, J. S., Bai, K. J. & Lai, G. M., 2016, In : Evidence-based Complementary and Alternative Medicine. 2016, 5989681.

Research output: Contribution to journal › Article

Neoplasms
Apoptosis
Lung Neoplasms
Proteins
Epithelial-Mesenchymal Transition
12 Citations (Scopus)

Activity-based and fraction-guided analysis of Phyllanthus urinaria identifies loliolide as a potent inhibitor of hepatitis C virus entry

Chung, C. Y., Liu, C. H., Burnouf, T., Wang, G. H., Chang, S. P., Jassey, A., Tai, C. J., Tai, C. J., Huang, C. J., Richardson, C. D., Yen, M. H., Lin, C. C. & Lin, L. T., Jun 1 2016, In : Antiviral Research. 130, p. 58-68 11 p.

Research output: Contribution to journal › Article

Phyllanthus
Virus Internalization
Hepacivirus
Antiviral Agents
Hepatitis C
21 Citations (Scopus)

Anti-cancer activity of Solanum nigrum (AESN) through suppression of mitochondrial function and epithelial-mesenchymal transition (EMT) in breast cancer cells

Lai, Y. J., Tai, C. J., Wang, C. W., Choong, C. Y., Lee, B. H., Shi, Y. C. & Tai, C. J., May 1 2016, In : Molecules. 21, 5, 553.

Research output: Contribution to journal › Article

Solanum nigrum
Epithelial-Mesenchymal Transition
breast
cancer
Cells
8 Citations (Scopus)

Aqueous extract of Paris polyphylla (AEPP) inhibits ovarian cancer via suppression of peroxisome proliferator-activated receptor-gamma coactivator (PGC)-1alpha

Wang, C. W., Tai, C. J., Choong, C. Y., Lin, Y. C., Lee, B. H., Shi, Y. C. & Tai, C. J., Jun 1 2016, In : Molecules. 21, 6, 727.

Research output: Contribution to journal › Article

PPAR gamma
Paris
Ovarian Neoplasms
Chemotherapy
cancer
7 Citations (Scopus)

Combination of Two Targeted Medications (Bevacizumab Plus Cetuximab) Improve the Therapeutic Response of Pancreatic Carcinoma

Tai, C. J., Huang, M. T., Wu, C. H., Wang, C. K., Tai, C. J., Chang, C. C., Hsieh, C. I., Chang, Y. J., Wu, C. J., Kuo, L. J., Wei, P. L., Chen, R. J. & Chiou, H. Y., Apr 1 2016, In : Medicine (United States). 95, 15, e3259.

Research output: Contribution to journal › Article

gemcitabine
Pancreatic Neoplasms
Nausea
Vomiting
Fluorouracil
8 Citations (Scopus)

Contrast-enhanced ultrasound and computed tomography assessment of hepatocellular carcinoma after transcatheter arterial chemo-embolization: A systematic review

Tai, C. J., Huang, M. T., Wu, C. H., Tai, C. J., Shi, Y. C., Chang, C. C., Chang, Y. J., Kuo, L. J., Wei, P. L., Chen, R. J. & Chiou, H. Y., Dec 1 2016, In : Journal of Gastrointestinal and Liver Diseases. 25, 4, p. 499-507 9 p.

Research output: Contribution to journal › Review article

Hepatocellular Carcinoma
Tomography
PubMed
Libraries
Therapeutics

Correction: Systematic discovery of drug action mechanisms by an integrated chemical genomics approach: Identification of functional disparities between azacytidine and decitabine [Oncotarget. 7, (2016), 27363-27378] doi 10.18632/oncotarget.8455

Hsieh, Y. Y., Huang, T. C., Lo, H. L., Jhan, J. Y., Chen, S. T. & Yang, P. M., May 10 2016, In : Oncotarget. 9, 64, p. 32402 1 p.

Research output: Contribution to journal › Comment/debate

decitabine
Azacitidine
Drug Discovery
Genomics
Medicine
24 Citations (Scopus)

Curative-Intent Aggressive Treatment Improves Survival in Elderly Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma and High Comorbidity Index

Chen, J. H., Yen, Y. C., Yang, H. C., Liu, S. H., Yuan, S. P., Wu, L. L., Lee, F. P., Lin, K. C., Lai, M. T., Wu, C. C., Chen, T. M., Chang, C. L., Chow, J. M., Ding, Y. F. & Wu, S. Y., Apr 1 2016, In : Medicine (United States). 95, 14, e3268.

Research output: Contribution to journal › Article

Comorbidity
Survival
Neoplasms
Radiotherapy
Therapeutics
15 Citations (Scopus)

EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells

Hsieh, Y-Y., Huang, H. L. & Yang, P-M., 2016, In : American Journal of Cancer Research. 6, 8, p. 1661-1680 20 p.

Research output: Contribution to journal › Article

Unfolded Protein Response
Autophagy
Colorectal Neoplasms
Up-Regulation
Endoplasmic Reticulum Stress
6 Citations (Scopus)

Glucose-regulated protein 94 mediates metastasis by CCT8 and the JNK pathway in hepatocellular carcinoma

Wei, P-L., Huang, C. Y., Tai, C-J., Batzorig, U., Cheng, W. L., Hunag, M. T. & Chang, Y-J., Jun 1 2016, In : Tumor Biology. 37, 6, p. 8219-8227 9 p.

Research output: Contribution to journal › Article

MAP Kinase Signaling System
Hepatocellular Carcinoma
Neoplasm Metastasis
Neoplasms
Wound Healing
5 Citations (Scopus)

Highly diverse efficacy of salvage treatment regimens for relapsed or refractory peripheral T-cell lymphoma: A systematic review

Yang, Y. T., Tai, C-J., Chen, C-F., Wu, H. C., Mikhaylichenko, N., Chiu, H. T., Chen, Y-Y. & Hsu, Y-H., Oct 1 2016, In : PLoS One. 11, 10

Research output: Contribution to journal › Review article

36 Citations (Scopus)

Inhibition of MDA-MB-231 breast cancer cell proliferation and tumor growth by apigenin through induction of G2/M arrest and histone H3 acetylation-mediated p21WAF1/CIP1 expression

Tseng, T. H., Chien, M. H., Lin, W. L., Wen, Y-C., Chow, J. M., Chen, C. K., Kuo, T. C. & Lee, W. J., 2016, (Accepted/In press) In : Environmental Toxicology.

Research output: Contribution to journal › Article

Apigenin
Acetylation
Cell proliferation
tumor
Histones