Projects per year
Organization profile
Organisation profile
Our department was established in 2002, and our graduate students are supervised by professors from the department of medicine and pharmacology as well. Our main goal is to educate professional researchers in the field of pharmacology, and to promote mechanism studies in our school.
The orientation of our goal is contingent upon the main research goals of our university such as cardiovascular and thrombus studies, natural products in Chinese medicine, the development and study of functional mechanisms in synthetic medicine. In accordance with clinical and pharmacological studies we also strive to strengthen the application of such studies.
Key Points of Middle and Long Term Research Plan:
(1) With the use of cloning and transfection genome-based biotechnology, we examine the different functions and effects of the target genetic polymorphism.
(2) Investigate vector transfection techniques, to better express or suppress specific genes in order to evaluate the effects of drug treatment on genes.
Fingerprint Dive into the research topics where Department of Pharmacology is active. These topic labels come from the works of this organisation's members. Together they form a unique fingerprint.
Blood Platelets
Medicine & Life Sciences
Platelets
Chemical Compounds
Platelet Activation
Medicine & Life Sciences
Platelet Aggregation
Medicine & Life Sciences
Chemical activation
Chemical Compounds
Phosphorylation
Medicine & Life Sciences
Apoptosis
Medicine & Life Sciences
p38 Mitogen-Activated Protein Kinases
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Projects 2010 2020
探討真菌衍生之抗神經發炎成分及其對視網膜疾病之療效評估(2/3)
8/1/19 → 7/1/20
Project: A - Government Institution › b - Ministry of Science and Technology
突觸支架蛋白Shank3調控神經發炎反應在急性缺血性腦中風之病理作用機制研究(1/2)
8/1/19 → 7/1/20
Project: A - Government Institution › b - Ministry of Science and Technology
新穎性長鏈烴基醯胺衍生物之抗癌與抗發炎活性與HDACs、miRNA媒介之後轉錄和後轉譯機轉探討
8/1/19 → 7/1/20
Project: A - Government Institution › b - Ministry of Science and Technology
Research Output 1977 2020
1
Citation
(Scopus)
N-alkyl-hydroxybenzoyl anilide hydroxamates as dual inhibitors of HDAC and HSP90, downregulating IFN-γ induced PD-L1 expression
Mehndiratta, S., Lin, M. H., Wu, Y. W., Chen, C. H., Wu, T. Y., Chuang, K. H., Chao, M. W., Chen, Y. Y., Pan, S. L., Chen, M. C. & Liou, J. P., Jan 1 2020, In : European Journal of Medicinal Chemistry. 185, p. 111725 111725.Research output: Contribution to journal › Article
Anilides
HSP90 Heat-Shock Proteins
Histone Deacetylase Inhibitors
Histone Deacetylases
Down-Regulation
A critical period for the development of schizophrenia-like pathology by aberrant postnatal neurogenesis
Sheu, J. R., Hsieh, C. Y., Jayakumar, T., Tseng, M. F., Lee, H. N., Huang, S. W., Manubolu, M. & Yang, C. H., Jan 1 2019, In : Frontiers in Neuroscience. 13, JUN, 635.Research output: Contribution to journal › Article
Open Access
Neurogenesis
Schizophrenia
Pathology
Critical Period (Psychology)
Hallucinations
1
Citation
(Scopus)
Autophagosome accumulation-mediated ATP energy deprivation induced by penfluridol triggers nonapoptotic cell death of lung cancer via activating unfolded protein response
Hung, W. Y., Chang, J. H., Cheng, Y., Cheng, G. Z., Huang, H. C., Hsiao, M., Chung, C. L., Lee, W. J. & Chien, M. H., Aug 1 2019, In : Cell Death and Disease. 10, 8, 538.Research output: Contribution to journal › Article
Open Access
Penfluridol
Unfolded Protein Response
Lung Neoplasms
Cell Death
Adenosine Triphosphate