Department of Pediatrics

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output 1979 2019

2019

Behavioral characteristics of autism spectrum disorder in very preterm birth children

Chen, L. W., Wang, S. T., Wang, L. W., Kao, Y. C., Chu, C. L., Wu, C. C., Hsieh, Y. T., Chiang, C. H. & Huang, C. C., Jul 22 2019, In : Molecular Autism. 10, 1, 32.

Research output: Contribution to journalArticle

Open Access
Premature Birth
Interpersonal Relations
Term Birth
Autism Spectrum Disorder
Gestational Age
Blood Urea Nitrogen
Glomerular Filtration Rate
Chronic Renal Insufficiency
Urea
Blood

Camptothecin activates SIRT1 to promote lipid catabolism through AMPK/FoxO1/ATGL pathway in C2C12 myogenic cells

Lo, M-C., Chen, J-Y., Kuo, Y-T., Chen, W-L., Lee, H-M. & Wang, S-G., Apr 24 2019, In : Archives of Pharmacal Research.

Research output: Contribution to journalArticle

Sirtuin 1
Adenylate Kinase
Camptothecin
Adenosine Monophosphate
Lipase
1 Citation (Scopus)
Hyperoxia
Rats
Air
Wounds and Injuries
Permeability

Cathelicidin attenuates hyperoxia-induced kidney injury in newborn rats

Chou, H. C. & Chen, C. M., Jan 1 2019, In : Renal Failure. 41, 1, p. 733-741 9 p.

Research output: Contribution to journalArticle

Open Access
Hyperoxia
Kidney
Wounds and Injuries
Air
Oxidative Stress

Developmental outcomes and prevalence of SLC2A1 variants in young infants with hypoglycorrhachia

Yu, W. H., Chen, L. W., Wang, S. T., Tu, Y. F. & Huang, C. C., Jan 1 2019, (Accepted/In press) In : Brain and Development.

Research output: Contribution to journalArticle

Facilitative Glucose Transport Proteins
Cerebrospinal Fluid
History
Glucose
Cell Count

Enterovirus A71 neurologic complications and long-term sequelae

Chang, L. Y., Lin, H. Y., Gau, S. S. F., Lu, C. Y., Hsia, S. H., Huang, Y. C., Huang, L. M. & Lin, T-Y., Aug 8 2019, In : Journal of Biomedical Science. 26, 1, 57.

Research output: Contribution to journalArticle

Open Access
Enterovirus
Neurology
Nervous System
Central Nervous System
Hand, Foot and Mouth Disease

ETF-QO Mutants Uncoupled Fatty Acid β-Oxidation and Mitochondrial Bioenergetics Leading to Lipid Pathology

Chokchaiwong, S., Kuo, Y-T., Hsu, S-P., Hsu, Y-C., Lin, S-H., Zhong, W-B., Lin, Y-F. & Kao, S-H., Jan 31 2019, In : Cells. 8, 2, p. 106

Research output: Contribution to journalArticle

Multiple Acyl Coenzyme A Dehydrogenase Deficiency
Acyl-CoA Dehydrogenase
Ubiquinone
Electron-Transferring Flavoproteins
Pathology
2 Citations (Scopus)
Wharton Jelly
Detergents
Platelets
Mesenchymal Stromal Cells
Blood Platelets

HDAC1,2 Knock-Out and HDACi Induced Cell Apoptosis in Imatinib-Resistant K562 Cells

Chen, S. H., Chow, J. M., Hsieh, Y. Y., Lin, C. Y., Hsu, K. W., Hsieh, W. S., Chi, W. M., Shabangu, B. M. & Lee, C. H., May 8 2019, In : International Journal of Molecular Sciences. 20, 9

Research output: Contribution to journalArticle

Open Access
Histone Deacetylase Inhibitors
K562 Cells
apoptosis
Cell death
inhibitors
Ventilator-Induced Lung Injury
Continuous Positive Airway Pressure
Lung Injury
Pneumonia
Respiration
Airway Remodeling
Matrix Metalloproteinases
Asthma
Antibodies
thymic stromal lymphopoietin

Maternal inflammation exacerbates neonatal hyperoxia-induced kidney injury in rat offspring

Chen, C. M. & Chou, H. C., Aug 1 2019, In : Pediatric Research. 86, 2, p. 174-180 7 p.

Research output: Contribution to journalArticle

Hyperoxia
Lipopolysaccharides
Mothers
Inflammation
Kidney
Hyperoxia
Lung Injury
Immunization
Oxidative Stress
Mothers
Hedgehogs
Urinary Bladder Neoplasms
Hedgehog Proteins
Muscles
Cadherins
3 Citations (Scopus)

Seasonal influenza prevention and control in Taiwan—Strategies revisited

Influenza Control Group & Infectious Disease Control Advisory Committee, Jan 1 2019, (Accepted/In press) In : Journal of the Formosan Medical Association.

Research output: Contribution to journalArticle

Human Influenza
Taiwan
Immunization Programs
Health
Advisory Committees
7 Citations (Scopus)

Structure–function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans

Huang, K. Y. A., Rijal, P., Jiang, H., Wang, B., Schimanski, L., Dong, T., Liu, Y. M., Chang, P., Iqbal, M., Wang, M. C., Chen, Z., Song, R., Huang, C. C., Yang, J. H., Qi, J., Lin, T. Y., Li, A., Powell, T. J., Jan, J. T., Ma, C. & 3 others, Gao, G. F., Shi, Y. & Townsend, A. R., Feb 1 2019, In : Nature Microbiology. 4, 2, p. 306-315 10 p.

Research output: Contribution to journalArticle

Neutralizing Antibodies
Human Influenza
Antibodies
Hemagglutinins
Binding Sites
Open Access
Petroselinum
G1 Phase Cell Cycle Checkpoints
Cell Cycle Resting Phase
G1 Phase
Nude Mice

Tetrac and NDAT Induce Anti-proliferation via Integrin αvβ3 in Colorectal Cancers With Different K-RAS Status

Chin, Y-T., He, Z-R., Chen, C-L., Chu, H-C., Ho, Y., Su, P-Y., Yang, Y-C. S. H., Wang, K., Shih, Y-J., Chen, Y-R., Pedersen, J. Z., Incerpi, S., Nana, A. W., Tang, H-Y., Lin, H-Y., Mousa, S. A., Davis, P. J. & Whang-Peng, J., 2019, In : Frontiers in Endocrinology. 10, p. 130

Research output: Contribution to journalArticle

Integrins
Colorectal Neoplasms
HCT116 Cells
Neoplasms
HT29 Cells

The Development and Applications of a Dual Optical Imaging System for Studying Glioma Stem Cells

Tai, P. A., Liu, Y. L., Wen, Y. T., Lin, C. M., Huynh, T. T., Hsiao, M., Wu, A. T. H. & Wei, L., Jan 1 2019, In : Molecular Imaging. 18

Research output: Contribution to journalArticle

Open Access
Optical Devices
stem cells
Optical Imaging
Stem cells
Glioma
1 Citation (Scopus)

Therapeutic Targeting of Non-oncogene Dependencies in High-risk Neuroblastoma

Huang, C-T., Hsieh, C-H., Lee, W-C., Liu, Y-L., Yang, T-S., Hsu, W-M., Oyang, Y-J., Huang, H-C. & Juan, H-F., Apr 5 2019, In : Clinical cancer research : an official journal of the American Association for Cancer Research.

Research output: Contribution to journalArticle

Neuroblastoma
Niclosamide
NM23 Nucleoside Diphosphate Kinases
Therapeutics
Drug Repositioning
2018

Acute aortoiliac thrombosis due to minimal change disease

Tam, W. C., Lin, C. H., Chuang, C. Y. & Cheng, C. Y., Apr 1 2018, In : Nephrology. 23, 4, p. 377-378 2 p.

Research output: Contribution to journalLetter

Lipoid Nephrosis
Thrombosis

Alpha-lipoic acid suppresses N ε -(carboxymethyl) lysine-induced epithelial mesenchymal transition in HK-2 human renal proximal tubule cells

Lo, M. C., Chen, M. H., Hsueh, Y. T., Kuo, Y. T. & Lee, H. M., Dec 2 2018, In : Free Radical Research. 52, 11-12, p. 1387-1397 11 p.

Research output: Contribution to journalArticle

Thioctic Acid
Proximal Kidney Tubule
Epithelial-Mesenchymal Transition
Hypoxia-Inducible Factor 1
Reactive Oxygen Species
2 Citations (Scopus)
Connective Tissue Growth Factor
Airway Remodeling
Matrix Metalloproteinases
Ovalbumin
Asthma
Interferon Regulatory Factors
Cleft Lip
Cleft Palate
Polymorphism
Meta-Analysis
1 Citation (Scopus)

Association of thiazolidinedione with a lower risk of Parkinson’s disease in a population with newly-diagnosed diabetes mellitus

Lin, H. L., Lin, H. C., Tseng, Y. F., Chao, J. C. J. & Hsu, C. Y., Jul 4 2018, In : Annals of Medicine. 50, 5, p. 430-436 7 p.

Research output: Contribution to journalArticle

Parkinson Disease
Diabetes Mellitus
Population
Cohort Studies
2,4-thiazolidinedione
2 Citations (Scopus)

Coenzyme Q10 serves to couple mitochondrial oxidative phosphorylation and fatty acid β-oxidation, and attenuates NLRP3 inflammasome activation

Chokchaiwong, S., Kuo, Y. T., Lin, S. H., Hsu, Y. C., Hsu, S. P., Liu, Y. T., Chou, A. J. & Kao, S. H., Jan 1 2018, (Accepted/In press) In : Free Radical Research.

Research output: Contribution to journalArticle

coenzyme Q10
Electron-Transferring Flavoproteins
Inflammasomes
Oxidative Phosphorylation
Ubiquinone

Corpus callosum and cerebellar vermis size in very preterm infants: Relationship to long-term neurodevelopmental outcome

Wu, P. M., Shih, H. I., Yu, W. H., Chen, L. W., Wang, L. C., Huang, C. C. & Tu, Y. F., Jan 1 2018, (Accepted/In press) In : Pediatrics and Neonatology.

Research output: Contribution to journalArticle

Corpus Callosum
Premature Infants
Cerebral Palsy
Intellectual Disability
Gestational Age
Plasmapheresis
Hypertriglyceridemia
Pancreatitis
Triglycerides
Therapeutics
3 Citations (Scopus)
Rheumatoid Arthritis
Anti-Inflammatory Agents
Stroke
Myocardial Infarction
Pharmaceutical Preparations
3 Citations (Scopus)
asthma
Pediatrics
immunity
Adaptive Immunity
Innate Immunity
1 Citation (Scopus)

Ferrous glycinate regulates cell energy metabolism by restricting hypoxia-induced factor-1α expression in human A549 cells

Kuo, Y-T., Jheng, J-H., Yang, M-C., Chen, W-L., Wang, S-G. & Lee, H-M., May 15 2018, In : Free Radical Research. p. 1-201 201 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Energy Metabolism
Pyruvic Acid
Prolyl-Hydroxylase Inhibitors
Oxidoreductases
Hyperoxia
Angiotensins
Lung Injury
Renin-Angiotensin System
Stem cells
3 Citations (Scopus)
Epithelial-Mesenchymal Transition
Renin-Angiotensin System
Streptozocin
Hyperglycemia
Gerbillinae
Experimental Diabetes Mellitus
Gerbillinae
Hyperglycemia
Lung
Pulmonary Fibrosis
3 Citations (Scopus)

Hypoxia-Preconditioned Human Umbilical Vein Endothelial Cells Protect Against Neurovascular Damage After Hypoxic Ischemia in Neonatal Brain

Lee, Y. C., Chang, Y. C., Wu, C. C. & Huang, C. C., Feb 19 2018, (Accepted/In press) In : Molecular Neurobiology. p. 1-15 15 p.

Research output: Contribution to journalArticle

Human Umbilical Vein Endothelial Cells
Ischemia
Brain
Hypoxia
Genes
2 Citations (Scopus)

Identifying Risk Factors Shared by Bronchopulmonary Dysplasia, Severe Retinopathy, and Cystic Periventricular Leukomalacia in Very Preterm Infants for Targeted Intervention

Wang, L. W., Lin, Y. C., Wang, S. T. & Huang, C. C., Apr 5 2018, (Accepted/In press) In : Neonatology. p. 17-24 8 p.

Research output: Contribution to journalArticle

Periventricular Leukomalacia
Bronchopulmonary Dysplasia
Retinopathy of Prematurity
Premature Infants
Artificial Respiration
4 Citations (Scopus)

Inhibitory effect of Anoectochilus formosanus extract on hyperglycemia-related PD-L1 expression and cancer proliferation

Ho, Y., Chen, Y. F., Wang, L. H., Hsu, K. Y., Chin, Y. T., Yang, Y. C. S. H., Wang, S. H., Chen, Y. R., Shih, Y. J., Liu, L. F., Wang, K., Whang-Peng, J., Tang, H. Y., Lin, H. Y., Liu, H. L. & Lin, S. J., Aug 2 2018, In : Frontiers in Pharmacology. 9, AUG, 807.

Research output: Contribution to journalArticle

Obese Mice
Hyperglycemia
Blood Glucose
Metformin
Hypoglycemic Agents
2 Citations (Scopus)

Letter to the editor: Occurrence of modified measles during outbreak in Taiwan in 2018

Chen, C. J., Lin, T. Y. & Huang, Y. C., Jan 1 2018, In : Eurosurveillance. 23, 37, 1800485.

Research output: Contribution to journalLetter

Measles
Taiwan
Disease Outbreaks
17 Citations (Scopus)

Machine learning–based radiomics for molecular subtyping of gliomas

Lu, C-F., Hsu, F-T., Hsieh, KL-C., Kao, Y-CJ., Cheng, S-J., Hsu, JB-K., Tsai, P-H., Chen, R-J., Huang, C-C., Yen, Y. & Chen, C-Y., Sep 15 2018, In : Clinical Cancer Research. 24, 18, p. 4429-4436 8 p.

Research output: Contribution to journalArticle

Glioma
Isocitrate Dehydrogenase
Histology
Phenotype
Glioblastoma
1 Citation (Scopus)

Molecular epidemiology and clinical features of rhinovirus infections among hospitalized patients in a medical center in Taiwan

Hung, H. M., Yang, S. L., Chen, C. J., Chiu, C. H., Kuo, C. Y., Huang, K. Y. A., Lin, T. Y., Hsieh, Y. C., Gong, Y. N., Tsao, K. C. & Huang, Y. C., Jan 1 2018, (Accepted/In press) In : Journal of Microbiology, Immunology and Infection.

Research output: Contribution to journalArticle

Rhinovirus
Molecular Epidemiology
Taiwan
Infection
Coinfection
2 Citations (Scopus)
Attention Deficit Disorder with Hyperactivity
Autistic Disorder
Newborn Infant
Cysts
Odds Ratio
3 Citations (Scopus)

Nano-Diamino-Tetrac (NDAT) Enhances Resveratrol-Induced Antiproliferation by Action on the RRM2 Pathway in Colorectal Cancers

Nana, A. W., Wu, S. Y., Yang, Y. C. S., Chin, Y. T., Cheng, T. M., Ho, Y., Li, W. S., Liao, Y. M., Chen, Y. R., Shih, Y. J., Liu, Y. R., Pedersen, J., Incerpi, S., Hercbergs, A., Liu, L. F., Whang-Peng, J., Davis, P. J. & Lin, H. Y., Oct 1 2018, In : Hormones and Cancer. 9, 5, p. 349-360 12 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Oxidoreductases
Neoplasms
Integrins
Stilbenes
2 Citations (Scopus)

Plasmon-activated water effectively relieves hepatic oxidative damage resulting from chronic sleep deprivation

Chen, H-C., Cheng, C-Y., Chen, L-Y., Chang, C-C., Yang, C-P., Mai, F-D., Liao, W-C., Chang, H-M. & Liu, Y-C., 2018, In : RSC Advances. 8, 18, p. 9618-9626 9 p.

Research output: Contribution to journalArticle

Water
Liver
Protective Agents
Rats
Sleep
Epidermal Growth Factor Receptor
Neoplasm Metastasis
Lung Neoplasms
Brain
Smoking
2 Citations (Scopus)
Cardiac Tamponade
Pericarditis
Staphylococcus aureus
5 Citations (Scopus)

Resveratrol inhibits human leiomyoma cell proliferation via crosstalk between integrin αvβ3 and IGF-1R

Ho, Y., SH Yang, Y. C., Chin, Y. T., Chou, S. Y., Chen, Y. R., Shih, Y. J., Whang-Peng, J., Changou, C. A., Liu, H. L., Lin, S. J., Tang, H. Y., Lin, H. Y. & Davis, P. J., Oct 1 2018, In : Food and Chemical Toxicology. 120, p. 346-355 10 p.

Research output: Contribution to journalArticle

resveratrol
integrins
Myoma
Cell proliferation
somatomedins
1 Citation (Scopus)

Seizure characteristics are related to tumor pathology in children with brain tumors

Tsai, M. L., Chen, C. L., Hsieh, K. L. C., Miser, J. S., Chang, H., Liu, Y. L. & Wong, T-T., Nov 1 2018, In : Epilepsy Research. 147, p. 15-21 7 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Seizures
Pathology
Neoplasms
etiracetam
1 Citation (Scopus)

Systemic 7,8-dihydroxyflavone treatment protects immature retinas against hypoxic-ischemic injury via müller glia regeneration and MAPK/ERK activation

Huang, H. M., Huang, C. C., Tsai, M. H., Poon, Y. C. & Chang, Y. C., Jun 1 2018, In : Investigative Ophthalmology and Visual Science. 59, 7, p. 3124-3135 12 p.

Research output: Contribution to journalArticle

Open Access
trkB Receptor
Newborn Animals
Ependymoglial Cells
Flavones
Electroretinography