Department of General Medicine

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output 1996 2019

Article

Noninsulinoma pancreatogenous hypoglycemic syndrome - A case report and review of literature

Lee, T. I., Yang, H. J., Wang, F. F., Won, G. S., Lee, M. T., Lin, H. D. & Tang, K. T., 2002, In : Journal of Internal Medicine of Taiwan. 13, 3, p. 133-140 8 p.

Research output: Contribution to journalArticle

Hypoglycemia
Hypoglycemic Agents
C-Peptide
Insulin
Glucagon
15 Citations (Scopus)

Observations on online services for diabetes management [3]

Liu, C. T., Yeh, Y. T., Lee, T. I. & Li, Y. C., 2005, In : Diabetes Care. 28, 11, p. 2807-2808 2 p.

Research output: Contribution to journalArticle

Computer-Assisted Instruction
User-Computer Interface
Blood Glucose Self-Monitoring
Cell Phones
Patient Education
34 Citations (Scopus)

Osthole enhances glucose uptake through activation of AMP-activated protein kinase in skeletal muscle cells

Lee, W. H., Lin, R-J., Lin, S. Y., Chen, Y. C., Lin, H. M. & Liang, Y. C., Dec 28 2011, In : Journal of Agricultural and Food Chemistry. 59, 24, p. 12874-12881 8 p.

Research output: Contribution to journalArticle

AMP-activated protein kinase
AMP-Activated Protein Kinases
myocytes
Muscle Cells
Muscle
28 Citations (Scopus)
Peroxisome Proliferator-Activated Receptors
Oxidative stress
Oxidative Stress
Inflammation
Medical problems
57 Citations (Scopus)

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

Que, X., Hung, M. Y., Yeang, C., Gonen, A., Prohaska, T. A., Sun, X., Diehl, C., Määttä, A., Gaddis, D. E., Bowden, K., Pattison, J., MacDonald, J. G., Ylä-Herttuala, S., Mellon, P. L., Hedrick, C. C., Ley, K., Miller, Y. I., Glass, C. K., Peterson, K. L., Binder, C. J. & 2 others, Tsimikas, S. & Witztum, J. L., Jun 14 2018, In : Nature. 558, 7709, p. 301-306 6 p.

Research output: Contribution to journalArticle

Phospholipids
Macrophages
Atherosclerosis
Peritoneal Macrophages
Inflammation
33 Citations (Scopus)

Peroxisome proliferator-activated receptors modulate cardiac dysfunction in diabetic cardiomyopathy

Lee, T. I., Kao, Y. H., Chen, Y. C., Huang, J. H., Hsiao, F. C. & Chen, Y. J., Jun 2013, In : Diabetes Research and Clinical Practice. 100, 3, p. 330-339 10 p.

Research output: Contribution to journalArticle

Diabetic Cardiomyopathies
Peroxisome Proliferator-Activated Receptors
Diabetes Mellitus
Homeostasis
Inflammation
9 Citations (Scopus)

Pheochromocytoma mimicking both acute coronary syndrome and sepsis: A case report

Lee, T. W., Lin, K. H., Chang, C. J., Lew, W. H. & Lee, T. I., Jun 2013, In : Medical Principles and Practice. 22, 4, p. 405-407 3 p.

Research output: Contribution to journalArticle

Pheochromocytoma
Acute Coronary Syndrome
Sepsis
Glandular and Epithelial Neoplasms
Adrenalectomy
2 Citations (Scopus)

Pheochromocytoma presenting as hyperglycemic hyperosmolar syndrome and unusual fever

Lee, I. S., Lee, T. W., Chang, C. J., Chien, Y. M. & Lee, T. I., Mar 3 2015, In : Internal and Emergency Medicine. 10, 6, p. 753-755 3 p.

Research output: Contribution to journalArticle

Hyperglycemic Hyperosmolar Nonketotic Coma
Adrenal Gland Neoplasms
Pheochromocytoma
Body Mass Index
Fever
70 Citations (Scopus)
Succinic Acid
Surface-Active Agents
Polysorbates
Pharmaceutical Preparations
Proteins
5 Citations (Scopus)
Polygonum
Thoracic Aorta
Vasodilation
Nitric Oxide Synthase
Endothelial Cells
13 Citations (Scopus)

Polygonum viviparum L. inhibits the lipopolysaccharide-induced inflammatory response in RAW264.7 macrophages through haem oxygenase-1 induction and activation of the Nrf2 pathway

Cheng, H. W., Lee, K. C., Cheah, K. P., Chang, M. L., Lin, C-W., Li, J. S., Yu, W. Y., Liu, E. T. & Hu, C. M., Feb 2013, In : Journal of the Science of Food and Agriculture. 93, 3, p. 491-497 7 p.

Research output: Contribution to journalArticle

Bistorta vivipara
NF-E2-Related Factor 2
Polygonum
Heme Oxygenase (Decyclizing)
oxygenases
19 Citations (Scopus)

Polymerase chain reaction diagnosis of Helicobacter pylori in gastroduodenal diseases: Comparison with culture and histopathological examinations

Lin, S. Y., Jeng, Y. S., Wang, C. K., Ko, F. T., Lin, K. Y., Wang, C. S., Liu, J. D., Chen, P. H. & Chang, J. G., 1996, In : Journal of Gastroenterology and Hepatology (Australia). 11, 3, p. 286-289 4 p.

Research output: Contribution to journalArticle

Helicobacter pylori
Polymerase Chain Reaction
Helicobacter Infections
Urease
Gastrointestinal Diseases
21 Citations (Scopus)

Postoperative adverse outcomes after non-hepatic surgery in patients with liver cirrhosis

Lin, C-S., Lin, S-Y., Chang, C-C., Wang, H. H., Liao, C-C. & Chen, T-L., Dec 2013, In : British Journal of Surgery. 100, 13, p. 1784-1790 7 p.

Research output: Contribution to journalArticle

Liver Cirrhosis
Odds Ratio
Mortality
Fibrosis
Confidence Intervals
11 Citations (Scopus)

Potential of vitamin D in treating diabetic cardiomyopathy

Lee, T. W., Lee, T. I., Chang, C. J., Lien, G. S., Kao, Y. H., Chao, T. F. & Chen, Y. J., Apr 1 2015, In : Nutrition Research. 35, 4, p. 269-279 11 p.

Research output: Contribution to journalArticle

Diabetic Cardiomyopathies
Vitamin D
Diabetes Mellitus
Cardiovascular Diseases
Hyperphosphatemia
18 Citations (Scopus)

Primary hypothalamic lymphoma with panhypopituitarism presenting as Stiff-man syndrome

Lee, M. T., Lee, T. I., Won, J. G. S., Chau, W. K., Yang, H. J., Li, J. C., Lin, H. D. & Tang, K. T., Aug 2004, In : American Journal of the Medical Sciences. 328, 2, p. 124-128 5 p.

Research output: Contribution to journalArticle

Stiff-Person Syndrome
Lymphoma
Myalgia
Thyroxine
Hydrocortisone
2 Citations (Scopus)

Primary Sjogren's syndrome and the risk of acute pancreatitis: A nationwide cohort study

Chang, C. C., Chang, Y. S., Wang, S. H., Lin, S. Y., Chen, Y. H. & Chen, J. H., Aug 1 2017, In : BMJ Open. 7, 8, e014807.

Research output: Contribution to journalArticle

Sjogren's Syndrome
Pancreatitis
Cohort Studies
Taiwan
Population
20 Citations (Scopus)
Peroxisome Proliferator-Activated Receptors
Cytokines
Ligands
Tumor Necrosis Factor-alpha
coenzyme Q10
32 Citations (Scopus)

Promoter CpG methylation caveolin-1 in sporadic colorectal cancer

Lin, S. Y., Yeh, K. T., Chen, W. T. L., Chen, H. C., Chen, S. T. & Chang, J. G., May 2004, In : Anticancer Research. 24, 3 A, p. 1645-1650 6 p.

Research output: Contribution to journalArticle

Caveolin 1
Methylation
Colorectal Neoplasms
Genes
Gene Silencing
39 Citations (Scopus)

Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features

Lin, S. Y., Yeh, K. T., Chen, W. T. L., Chen, H. C., Chen, S. T., Chiou, H. Y. & Chang, J. G., Feb 2004, In : Oncology Reports. 11, 2, p. 341-348 8 p.

Research output: Contribution to journalArticle

Tumor Suppressor Genes
Methylation
Colorectal Neoplasms
Glycogen Synthase Kinase 3
Cadherins
30 Citations (Scopus)

Pro-oxidant and cytotoxic activities of atractylenolide I in human promyeloleukemic HL-60 cells

Wang, C. C., Lin, S. Y., Cheng, H. C. & Hou, W. C., Aug 2006, In : Food and Chemical Toxicology. 44, 8, p. 1308-1315 8 p.

Research output: Contribution to journalArticle

HL-60 Cells
oxidants
Reactive Oxygen Species
Cytotoxicity
superoxide dismutase
43 Citations (Scopus)

Rab18 facilitates dengue virus infection by targeting fatty acid synthase to sites of viral replication

Tang, W. C., Lin, R. J., Liao, C. L. & Lin, Y. L., 2014, In : Journal of Virology. 88, 12, p. 6793-6804 12 p.

Research output: Contribution to journalArticle

Fatty Acid Synthases
Dengue virus
fatty-acid synthase
Dengue Virus
Virus Diseases

Recent Advances in Cancer Therapy Research

Lin, S-Y., Dec 2002, In : New Taipei Journal of Medicine. 4, 4, p. 205-209 5 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)
Osmotic Pressure
Drug Delivery Systems
Tablets
Rupture
Membranes
1 Citation (Scopus)

Research update for articles published in EJCI in 2010

Adlbrecht, C., Aigner, E., Bellón, J. M., Bouloukaki, I., Bouzas-Mosquera, A., Carrilho, A. J. F., Chang, K. C., Chattipakorn, N., Chattipakorn, S. C., Chen, Y. J., Chung, Y. C., Colah, R., Datz, C., Frøkjær, J. B., Fujimori, S., Georgiadou, P., Grion, C. M., Hsu, C. P., Hülsmann, M., Hung, M. J. & 16 others, Hung, M. Y., Iliodromitis, E. K., Lang, I. M., Lee, T. I., März, W., Nair, S. B., Pascual, G., Peteiro, J., Sakamoto, C., Satomura, A., Schiza, S. E., Stärkel, P., Stojakovic, T., Vesely, D. L., Walters, D. L. & Yilmaz, Y., Nov 2012, In : European Journal of Clinical Investigation. 42, 11, p. 1149-1164 16 p.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Rosiglitazone induces arrhythmogenesis in diabetic hypertensive rats with calcium handling alteration

Lee, T. I., Chen, Y. C., Kao, Y. H., Hsiao, F. C., Lin, Y. K. & Chen, Y. J., May 10 2013, In : International Journal of Cardiology. 165, 2, p. 299-307 9 p.

Research output: Contribution to journalArticle

rosiglitazone
Inbred SHR Rats
Calcium
Hypertension
Ryanodine Receptor Calcium Release Channel

Rotura traqueal yatrogénica tras una intubación de urgencia

Translated title of the contribution: Iatrogenic Tracheal Rupture After Emergent IntubationChou, C. L., Lee, T. I. & Hu, T. Y., Feb 1 2017, In : Archivos de Bronconeumologia. 53, 2, p. 75-76 2 p.

Research output: Contribution to journalArticle

Intubation
Rupture

Shikonin derivatives inhibited LPS-induced NOS in RAW 264.7 cells via downregulation of MAPK/NF-kappaB signaling

Cheng, Y. W., Chang, C. Y., Lin, K. L., Hu, C. M., Lin, C. H. & Kang, J. J., Nov 20 2008, In : Journal of Ethnopharmacology. 120, 2, p. 264-71 8 p.

Research output: Contribution to journalArticle

NF-kappa B
Lipopolysaccharides
Down-Regulation
Lithospermum
Naphthoquinones
4 Citations (Scopus)

Silent myocardial ischemia in coronary artery disease patients under aspirin therapy presenting with upper gastrointestinal hemorrhage

Chen, C. C., Chong, C. F., Kuo, C. D. & Wang, Z-L., 2007, In : Journal of Gastroenterology and Hepatology (Australia). 22, 1, p. 13-17 5 p.

Research output: Contribution to journalArticle

Gastrointestinal Hemorrhage
Aspirin
Myocardial Ischemia
Coronary Artery Disease
Length of Stay
27 Citations (Scopus)
Dextromethorphan
Plasma (human)
Metabolites
Dextrorphan
High Pressure Liquid Chromatography
1 Citation (Scopus)

Sitagliptin modulates the electrical and mechanical characteristics of pulmonary vein and atrium

Chang, C. J., Yang, T. F., Lee, T. I., Chen, Y. C., Kao, Y. H., Chen, S. A. & Chen, Y. J., 2014, In : Acta Cardiologica Sinica. 30, 1, p. 29-37 9 p.

Research output: Contribution to journalArticle

Pulmonary Veins
Inbred WKY Rats
Inbred SHR Rats
Heart Atria
pamidronate

Sodium hydrosulphide restores tumour necrosis factor-α-induced mitochondrial dysfunction and metabolic dysregulation in HL-1 cells

Lee, T. I., Kao, Y. H., Baigalmaa, L., Lee, T. W., Lu, Y. Y., Chen, Y. C., Chao, T. F. & Chen, Y. J., Jan 1 2019, (Accepted/In press) In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journalArticle

Open Access
Peroxisome Proliferator-Activated Receptors
Tumor Necrosis Factor-alpha
Adenosine Triphosphate
Cardiac Myocytes
Oxidative Stress
10 Citations (Scopus)

Somatostatin analogue mimics acute ischemic preconditioning in a rat model of myocardial infarction

Wang, Z-L., Huang, Y. H. & Chang, H., Apr 2005, In : Journal of Cardiovascular Pharmacology. 45, 4, p. 327-332 6 p.

Research output: Contribution to journalArticle

Ischemic Preconditioning
Octreotide
Somatostatin
Myocardial Infarction
KATP Channels
24 Citations (Scopus)

Stereoselective effects of 3-hydroxybutyrate on glucose utilization of rat cardiomyocytes

Tsai, Y. C., Chou, Y. C., Wu, A-B., Hu, C-M., Chen, C. Y., Chen, F. A. & Lee, J. A., Feb 16 2006, In : Life Sciences. 78, 12, p. 1385-1391 7 p.

Research output: Contribution to journalArticle

3-Hydroxybutyric Acid
Cardiac Myocytes
Rats
Glucose
Ketone Bodies
4 Citations (Scopus)

Subcapsular renal hematoma complicating acute pyelonephritis

You, C. F., Chong, C. F., Wang, Z-L. & Chen, C. C., Oct 2010, In : Journal of Emergency Medicine. 39, 4, p. 440-442 3 p.

Research output: Contribution to journalArticle

Pyelonephritis
Hematoma
Kidney
28 Citations (Scopus)

Suppression of Fas ligand expression on endothelial cells by arsenite through reactive oxygen species

Tsai, S. H., Hsieh, M-S., Chen, L., Liang, Y. C., Lin, J. K. & Lin, S. Y., Aug 6 2001, In : Toxicology Letters. 123, 1, p. 11-19 9 p.

Research output: Contribution to journalArticle

Fas Ligand Protein
Endothelial cells
Reactive Oxygen Species
Endothelial Cells
Vascular Diseases
2 Citations (Scopus)

Surface assembly of poly(I:C) on polyethyleneimine-modified gelatin nanoparticles as immunostimulatory carriers for mucosal antigen delivery

Lin, S. F., Jiang, P. L., Tsai, J. S., Huang, Y. Y., Lin, S. Y., Lin, J. H. & Liu, D. Z., Jan 1 2018, (Accepted/In press) In : Journal of Biomedical Materials Research - Part B Applied Biomaterials.

Research output: Contribution to journalArticle

Polyethyleneimine
Poly I-C
Gelatin
Antigens
Ovalbumin
2 Citations (Scopus)

Surface-enhanced Raman scattering on a silver film-modified Au nanoparticle-decorated SiO2 mask array

Chang, C. C., Chen, L. Y., Yang, K. H., Chen, Q. Y., Liang, Y. C., Lin, S. Y. & Liu, Y. C., Jul 23 2015, In : RSC Advances. 5, 81, p. 66096-66103 8 p.

Research output: Contribution to journalArticle

Silver
Raman scattering
Masks
Nanoparticles
Calcium
20 Citations (Scopus)

Sustained release of 5-FU from Poloxamer gels interpenetrated by crosslinking chitosan network

Chung, T. W., Lin, S. Y., Liu, D. Z., Tyan, Y. C. & Yang, J. S., Dec 1 2009, In : International Journal of Pharmaceutics. 382, 1-2, p. 39-44 6 p.

Research output: Contribution to journalArticle

Poloxamer
Chitosan
Fluorouracil
Gels
Glutaral
12 Citations (Scopus)

Switch activation of PI-PLC downstream signals in activated macrophages with wortmannin

Liu, D. Z., Liang, H. J., Chen, C. H., Lin, S. Y., Zhong, W-B., Ho, F. M., Hou, W. C., Lo, J. L., Ho, Y. S., Lin, P. J., Hung, L. F. & Liang, Y. C., Jun 2007, In : Biochimica et Biophysica Acta - Molecular Cell Research. 1773, 6, p. 869-879 11 p.

Research output: Contribution to journalArticle

Phosphoinositide Phospholipase C
Phosphatidylinositol 3-Kinase
Macrophages
Plasmids
Phosphatidylinositol 4,5-Diphosphate
6 Citations (Scopus)
Dioscorea
Dipeptidyl Peptidase 4
yams
glucose tolerance
Glucose Tolerance Test
9 Citations (Scopus)

Taiwanofungus camphoratus activates peroxisome proliferator-activated receptors and induces hypotriglyceride in hypercholesterolemic rats

Suk, F. M., Lin, S. Y., Chen, C. H., Yen, S. J., Su, C. H., Liu, D. Z., Hou, W. C., Hung, L. F., Lin, P. J. & Liang, Y. C., 2008, In : Bioscience, Biotechnology and Biochemistry. 72, 7, p. 1704-1713 10 p.

Research output: Contribution to journalArticle

Taiwanofungus camphoratus
Peroxisome Proliferator-Activated Receptors
PPAR gamma
Rats
fruiting bodies
18 Citations (Scopus)

Testosterone replacement increases aged pulmonary vein and left atrium arrhythmogenesis with enhanced adrenergic activity

Tsai, W. C., Lee, T-I., Chen, Y. C., Kao, Y-H., Lu, Y. Y., Lin, Y-K., Chen, S. A. & Chen, Y-J., 2014, In : International Journal of Cardiology. 176, 1, p. 110-118 9 p.

Research output: Contribution to journalArticle

Pulmonary Veins
Heart Atria
Adrenergic Agents
Testosterone
Rabbits
30 Citations (Scopus)

The accuracy of fine-needle aspiration biopsy and frozen section in patients with thyroid cancer

Lee, T. I., Yang, H. J., Lin, S. Y., Lee, M. T., Lin, H. D., Braverman, L. E. & Tang, K. T., 2002, In : Thyroid. 12, 7, p. 619-626 8 p.

Research output: Contribution to journalArticle

Frozen Sections
Fine Needle Biopsy
Thyroid Neoplasms
Thyroid Nodule
Thyroidectomy
9 Citations (Scopus)
Nicotinic Receptors
Nicotine
Breast Neoplasms
Neoplasm Metastasis
Cell Movement
1 Citation (Scopus)

The antinociceptive and anti-inflammatory activities of Petasites formosanus Kitamura extract

Lin, S. Y., Teng, H. L., Tseng, S. H., Chen, L. G. & Wang, C. C., Oct 2012, In : Botanical Studies. 53, 4, p. 431-438 8 p.

Research output: Contribution to journalArticle

Petasites
anti-inflammatory activity
leaf extracts
carrageenan
edema
3 Citations (Scopus)
Thyroid Diseases
Thyrotropin
Autoimmune Diseases
Hashimoto Disease
Thyroidectomy
25 Citations (Scopus)
Dipeptidyl-Peptidase IV Inhibitors
Peroxisome Proliferator-Activated Receptors
Cardiac Myocytes
Inbred SHR Rats
Inflammation
47 Citations (Scopus)

The influence of diabetes, glycemic control, and diabetes-related comorbidities on pulmonary tuberculosis

Chiang, C. Y., Bai, K. J., Lin, H. H., Chien, S. T., Lee, J. J., Enarson, D. A., Lee, T. I. & Yu, M. C., Mar 30 2015, In : PLoS One. 10, 3, e0121698.

Research output: Contribution to journalArticle

glycemic control
Medical problems
Pulmonary Tuberculosis
tuberculosis
diabetes
22 Citations (Scopus)

The possible role of heat shock factor-1 in the negative regulation of heme oxygenase-1

Chou, Y. H., Ho, F. M., Liu, D. Z., Lin, S. Y., Tsai, L-H., Chen, C. H., Ho, Y. S., Hung, L. F. & Liang, Y. C., Mar 2005, In : International Journal of Biochemistry and Cell Biology. 37, 3, p. 604-615 12 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Shock
Hot Temperature
Gene expression
Gene Expression
8 Citations (Scopus)

The relationship between morning serum cortisol and the short ACTH test in the evaluation of adrenal insufficiency

Lee, M. T., Won, J. G. S., Lee, T. I., Yang, H. J., Lin, H. D. & Tang, K. T., Dec 1 2003, In : Chinese Medical Journal (Taipei). 65, 12, p. 580-587 8 p.

Research output: Contribution to journalArticle

Adrenal Insufficiency
Adrenocorticotropic Hormone
Hydrocortisone
Serum
Intravenous Injections