Department of General Medicine

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output 1996 2019

1996
19 Citations (Scopus)

Polymerase chain reaction diagnosis of Helicobacter pylori in gastroduodenal diseases: Comparison with culture and histopathological examinations

Lin, S. Y., Jeng, Y. S., Wang, C. K., Ko, F. T., Lin, K. Y., Wang, C. S., Liu, J. D., Chen, P. H. & Chang, J. G., 1996, In : Journal of Gastroenterology and Hepatology (Australia). 11, 3, p. 286-289 4 p.

Research output: Contribution to journalArticle

Helicobacter pylori
Polymerase Chain Reaction
Helicobacter Infections
Urease
Gastrointestinal Diseases
1998
12 Citations (Scopus)

Multiple truncated transcripts of TSG101 in gastrointestinal cancers

Lin, S. Y., Chen, Y. J. & Chang, J. G., 1998, In : Journal of Gastroenterology and Hepatology (Australia). 13, 11, p. 1111-1114 4 p.

Research output: Contribution to journalArticle

Gastrointestinal Neoplasms
Stomach
Esophageal Neoplasms
Tumor Suppressor Genes
Reverse Transcriptase Polymerase Chain Reaction
1999
3 Citations (Scopus)

Analysis of aberrant transcription of TSG101 in hepatocellular carcinomas

Chen, Y. J., Chen, P. H., Lin, S. Y. & Chang, J. G., Feb 1999, In : European Journal of Cancer. 35, 2, p. 302-308 7 p.

Research output: Contribution to journalArticle

Hepatocellular Carcinoma
Genes
Chromosomes
Choristoma
Cell Line

MSH2 and MLH1 Expression in Sporadic Colorectal Cancer

Lin, S-Y., Wang, C. K., Pan, S., Chen, Y-J. & Liu, J-D., Jun 2000, In : New Taipei Journal of Medicine. 2, 2, p. 109-113 5 p.

Research output: Contribution to journalArticle

2001
98 Citations (Scopus)
Liver Neoplasms
Liver
Colonic Neoplasms
Cells
Apoptosis
69 Citations (Scopus)

Molecular mechanisms of apoptosis induced by magnolol in colon and liver cancer cells

Lin, S. Y., Chang, Y. T., Liu, J-D., Yu, C. H., Ho, Y. S., Lee, Y-H. & Lee, W. S., 2001, In : Molecular Carcinogenesis. 32, 2, p. 73-83 11 p.

Research output: Contribution to journalArticle

Liver Neoplasms
Colonic Neoplasms
Caspase 8
Apoptosis
Caspase 9
28 Citations (Scopus)

Suppression of Fas ligand expression on endothelial cells by arsenite through reactive oxygen species

Tsai, S. H., Hsieh, M-S., Chen, L., Liang, Y. C., Lin, J. K. & Lin, S. Y., Aug 6 2001, In : Toxicology Letters. 123, 1, p. 11-19 9 p.

Research output: Contribution to journalArticle

Fas Ligand Protein
Endothelial cells
Reactive Oxygen Species
Endothelial Cells
Vascular Diseases
2002
21 Citations (Scopus)

Antitumor effects of miconazole on human colon carcinoma xenografts in nude mice through induction of apoptosis and G0/G1 cell cycle arrest

Wu, C. H., Jeng, J. H., Wang, Y. J., Tseng, C. J., Liang, Y. C., Chen, C. H., Lee, H. M., Lin, J. K., Lin, C-H., Lin, S. Y., Li, C. P. & Ho, Y. S., Apr 1 2002, In : Toxicology and Applied Pharmacology. 180, 1, p. 22-35 14 p.

Research output: Contribution to journalArticle

G1 Phase Cell Cycle Checkpoints
Miconazole
Heterografts
Nude Mice
Colon
36 Citations (Scopus)
JNK Mitogen-Activated Protein Kinases
Extracellular Signal-Regulated MAP Kinases
Tetradecanoylphorbol Acetate
Colonic Neoplasms
Up-Regulation
22 Citations (Scopus)

Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity

Wang, Y. J., Yu, C. F., Chen, L. C., Chen, C. H., Lin, J. K., Liang, Y. C., Lin, C. H., Lin, S. Y., Chen, C. F. & Ho, Y. S., 2002, In : Journal of Cellular Biochemistry. 87, 2, p. 147-159 13 p.

Research output: Contribution to journalArticle

Terfenadine
Cytochrome P-450 CYP3A
Ketoconazole
Hep G2 Cells
Apoptosis

Noninsulinoma pancreatogenous hypoglycemic syndrome - A case report and review of literature

Lee, T. I., Yang, H. J., Wang, F. F., Won, G. S., Lee, M. T., Lin, H. D. & Tang, K. T., 2002, In : Journal of Internal Medicine of Taiwan. 13, 3, p. 133-140 8 p.

Research output: Contribution to journalArticle

Hypoglycemia
Hypoglycemic Agents
C-Peptide
Insulin
Glucagon

Recent Advances in Cancer Therapy Research

Lin, S-Y., Dec 2002, In : New Taipei Journal of Medicine. 4, 4, p. 205-209 5 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

The accuracy of fine-needle aspiration biopsy and frozen section in patients with thyroid cancer

Lee, T. I., Yang, H. J., Lin, S. Y., Lee, M. T., Lin, H. D., Braverman, L. E. & Tang, K. T., 2002, In : Thyroid. 12, 7, p. 619-626 8 p.

Research output: Contribution to journalArticle

Frozen Sections
Fine Needle Biopsy
Thyroid Neoplasms
Thyroid Nodule
Thyroidectomy

Ventricular dysfunction in a patient with Plummer's disease: A case report

Lee, T. I., Lin, C. C., Chan, T. S., Chan, P. & Chen, Y. J., 2002, In : Heart and Vessels. 16, 3, p. 118-120 3 p.

Research output: Contribution to journalArticle

Ventricular Dysfunction
Sinus Tachycardia
Nodular Goiter
Cardiomegaly
Triiodothyronine
2003
2 Citations (Scopus)

A reappraisal of the ovine corticotropin-releasing hormone stimulation test in the differential diagnosis of cushing's syndrome: A comparison with the standard high-dose dexamethasone suppression test

Lee, T. I. T. I., Lin, S. Y., Won, J. G. S., Tang, K. T., Jap, T. S., Kwok, C. F. & Lin, H. D., Jan 1 2003, In : Chinese Medical Journal (Taipei). 65, 10, p. 474-482 9 p.

Research output: Contribution to journalArticle

Cushing Syndrome
Corticotropin-Releasing Hormone
Dexamethasone
Sheep
Differential Diagnosis
14 Citations (Scopus)

Inflammatory Pseudotumor Resulting from Foreign Body in Abdominal Cavity Detected by FDG PET

Hsu, C-H., Lee, C-M. & Lin, S-Y., Oct 2003, In : Clinical Nuclear Medicine. 28, 10, p. 842-844 3 p.

Research output: Contribution to journalArticle

Plasma Cell Granuloma
Abdominal Cavity
Foreign Bodies
Abdomen
Body Image
53 Citations (Scopus)

In vitro and in vivo studies of the anticancer action of terbinafine in human cancer cell lines: G0/G1 p53-associated cell cycle arrest

Lee, W. S., Chen, R. J., Wang, Y. J., Tseng, H., Jeng, J. H., Lin, S. Y., Liang, Y. C., Chen, C. H., Lin, C. H., Lin, J. K., Ho, P. Y., Chu, J. S., Ho, W. L., Chen, L. C. & Ho, Y. S., Aug 10 2003, In : International Journal of Cancer. 106, 1, p. 125-137 13 p.

Research output: Contribution to journalArticle

terbinafine
Cell Cycle Checkpoints
Cell Line
Neoplasms
In Vitro Techniques
30 Citations (Scopus)
JNK Mitogen-Activated Protein Kinases
Stomach
Epithelial Cells
Phosphotransferases
Apoptosis
8 Citations (Scopus)

The relationship between morning serum cortisol and the short ACTH test in the evaluation of adrenal insufficiency

Lee, M. T., Won, J. G. S., Lee, T. I., Yang, H. J., Lin, H. D. & Tang, K. T., Dec 1 2003, In : Chinese Medical Journal (Taipei). 65, 12, p. 580-587 8 p.

Research output: Contribution to journalArticle

Adrenal Insufficiency
Adrenocorticotropic Hormone
Hydrocortisone
Serum
Intravenous Injections
2004
14 Citations (Scopus)

Anti-proliferation effect of 5,5-diphenyl-2-thiohydantoin (DPTH) in human vascular endothelial cells

Shih, C. R., Wu, J., Liu, Y., Liang, Y. C., Lin, S. Y., Sheu, M. T. & Lee, W. S., Jan 1 2004, In : Biochemical Pharmacology. 67, 1, p. 67-75 9 p.

Research output: Contribution to journalArticle

Endothelial cells
Human Umbilical Vein Endothelial Cells
Endothelial Cells
Phosphotransferases
Thymidine
18 Citations (Scopus)

Primary hypothalamic lymphoma with panhypopituitarism presenting as Stiff-man syndrome

Lee, M. T., Lee, T. I., Won, J. G. S., Chau, W. K., Yang, H. J., Li, J. C., Lin, H. D. & Tang, K. T., Aug 2004, In : American Journal of the Medical Sciences. 328, 2, p. 124-128 5 p.

Research output: Contribution to journalArticle

Stiff-Person Syndrome
Lymphoma
Myalgia
Thyroxine
Hydrocortisone
32 Citations (Scopus)

Promoter CpG methylation caveolin-1 in sporadic colorectal cancer

Lin, S. Y., Yeh, K. T., Chen, W. T. L., Chen, H. C., Chen, S. T. & Chang, J. G., May 2004, In : Anticancer Research. 24, 3 A, p. 1645-1650 6 p.

Research output: Contribution to journalArticle

Caveolin 1
Methylation
Colorectal Neoplasms
Genes
Gene Silencing
39 Citations (Scopus)

Promoter CpG methylation of tumor suppressor genes in colorectal cancer and its relationship to clinical features

Lin, S. Y., Yeh, K. T., Chen, W. T. L., Chen, H. C., Chen, S. T., Chiou, H. Y. & Chang, J. G., Feb 2004, In : Oncology Reports. 11, 2, p. 341-348 8 p.

Research output: Contribution to journalArticle

Tumor Suppressor Genes
Methylation
Colorectal Neoplasms
Glycogen Synthase Kinase 3
Cadherins
27 Citations (Scopus)

Thiol antioxidant and thiol-reducing agents attenuate 15-deoxy-Δ 12,14-prostaglandin J2-induced heme oxygenase-1 expression

Liu, J-D., Tsai, S. H., Lin, S. Y., Ho, Y. S., Hung, L. F., Pan, S., Ho, F. M., Lin, C. M. & Liang, Y. C., Mar 26 2004, In : Life Sciences. 74, 19, p. 2451-2463 13 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Reducing Agents
Sulfhydryl Compounds
Antioxidants
Dithiothreitol
2005
20 Citations (Scopus)

Antioxidant activities of mucilages from different Taiwanese yam cultivars

Lin, S. Y., Liu, H. Y., Lu, Y. L. & Hou, W. C., Jul 2005, In : Botanical Bulletin of Academia Sinica. 46, 3, p. 183-188 6 p.

Research output: Contribution to journalArticle

mucilages
yams
antioxidant activity
cultivars
hydroxyl radicals
74 Citations (Scopus)

Balthazar computed tomography severity index is superior to Ranson criteria and APACHE II scoring system in predicting acute pancreatitis outcome

Leung, T-K., Lee, C-M., Lin, S. Y., Chen, H. C., Wang, H. J., Shen, L. K. & Chen, Y. Y., Oct 14 2005, In : World Journal of Gastroenterology. 11, 38, p. 6049-6052 4 p.

Research output: Contribution to journalArticle

APACHE
Pancreatitis
Tomography
Spiral Computed Tomography
Hospitalization
3 Citations (Scopus)

Elevated nitric oxide levels inhibit malondialdehyde production in patients with diabetes mellitus in Taiwan [2]

Lee, T. I., Sun, M. F., Wen, Y. R., Kuo, P. L. & Liu, C. F., Dec 2005, In : Nutrition, Metabolism and Cardiovascular Diseases. 15, 6, p. 452-453 2 p.

Research output: Contribution to journalArticle

Malondialdehyde
Type 1 Diabetes Mellitus
Taiwan
Type 2 Diabetes Mellitus
Case-Control Studies
27 Citations (Scopus)

Involvement of fatty acid-CoA ligase 4 in hepatocellular carcinoma growth: Roles of cyclic AMP and p38 mitogen-activated protein kinase

Liang, Y. C., Wu, C. H., Chu, J. S., Wang, C. K., Hung, L. F., Wang, Y. J., Ho, Y. S., Chang, J. G. & Lin, S. Y., May 7 2005, In : World Journal of Gastroenterology. 11, 17, p. 2557-2563 7 p.

Research output: Contribution to journalArticle

p38 Mitogen-Activated Protein Kinases
Coenzyme A
Ligases
Cyclic AMP
Hepatocellular Carcinoma
24 Citations (Scopus)

Molecular mechanisms of denbinobin-induced anti-tumorigenesis effect in colon cancer cells

Yang, K-C., Uen, Y. H., Suk, F. M., Liang, Y. C., Wang, Y. J., Ho, Y. S., Li, I. H. & Lin, S. Y., May 28 2005, In : World Journal of Gastroenterology. 11, 20, p. 3040-3045 6 p.

Research output: Contribution to journalArticle

Colonic Neoplasms
Carcinogenesis
Apoptosis Inducing Factor
Apoptosis
Caspase 8
30 Citations (Scopus)
Econazole
G1 Phase Cell Cycle Checkpoints
caspase-8
Caspase 8
colorectal neoplasms
15 Citations (Scopus)

Observations on online services for diabetes management [3]

Liu, C. T., Yeh, Y. T., Lee, T. I. & Li, Y. C., 2005, In : Diabetes Care. 28, 11, p. 2807-2808 2 p.

Research output: Contribution to journalArticle

Computer-Assisted Instruction
User-Computer Interface
Blood Glucose Self-Monitoring
Cell Phones
Patient Education
68 Citations (Scopus)
Succinic Acid
Surface-Active Agents
Polysorbates
Pharmaceutical Preparations
Proteins
10 Citations (Scopus)

Somatostatin analogue mimics acute ischemic preconditioning in a rat model of myocardial infarction

Wang, Z-L., Huang, Y. H. & Chang, H., Apr 2005, In : Journal of Cardiovascular Pharmacology. 45, 4, p. 327-332 6 p.

Research output: Contribution to journalArticle

Ischemic Preconditioning
Octreotide
Somatostatin
Myocardial Infarction
KATP Channels
22 Citations (Scopus)

The possible role of heat shock factor-1 in the negative regulation of heme oxygenase-1

Chou, Y. H., Ho, F. M., Liu, D. Z., Lin, S. Y., Tsai, L-H., Chen, C. H., Ho, Y. S., Hung, L. F. & Liang, Y. C., Mar 2005, In : International Journal of Biochemistry and Cell Biology. 37, 3, p. 604-615 12 p.

Research output: Contribution to journalArticle

Heme Oxygenase-1
Shock
Hot Temperature
Gene expression
Gene Expression

結合醫院就醫資訊之糖尿病衛生教育網際網路系統之返診成效評估

Translated title of the contribution: Evaluation on Return Rates of Follow-ups for An Integrated Diabetes Patient-Centered Education SystemLiu, C-T., Yeh, Y-T., Lee, T-I., Hsu, C-Y. & Li, Y-C., 2005, In : 醫療資訊雜誌. 14, 2, p. 17-25 9 p.

Research output: Contribution to journalArticle

Medical problems
Education
Electronic mail
Websites
Internet

結合醫院臨床照護與衛生教育網際網路服務系統-以糖尿病為例

Translated title of the contribution: A framework for integrating information of clinical care into patient education for diabetesYeh, Y-T., Lee, T-I., Hsu, C-Y., Long, A-J., Li, Y-C. & Liu, C-T., 2005, In : 醫療資訊雜誌. 14, 1, p. 15-24 10 p.

Research output: Contribution to journalArticle

Medical problems
Education
Information systems
Internet
2006
1 Citation (Scopus)

Chronic bifascicular block with intermittent complete atrioventricular block induced by hyperthyroidism

Kuo, Y. C., Tseng, Y. T., Lee, T. I. & Hsieh, M. H., Jun 28 2006, In : International Journal of Cardiology. 110, 3, p. 407-410 4 p.

Research output: Contribution to journalArticle

Atrioventricular Node
Atrioventricular Block
Hyperthyroidism
Heart Diseases
Electrocardiography
9 Citations (Scopus)

Development and evaluation of an integrated patient-oriented education management system for diabetes

Yeh, Y-T., Chiu, Y. T., Liu, C-T., Wu, S. J. & Lee, T-I., 2006, Studies in Health Technology and Informatics. Vol. 122. p. 172-175 4 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Patient Education
Medical problems
Education
Glucose
Self Care
33 Citations (Scopus)
Dioscorea alata
Dioscorea
yams
Blood pressure
Inbred SHR Rats
20 Citations (Scopus)

Influence of iron on the severity of hepatic fibrosis in patients with chronic hepatitis C

Lin, T. J., Liao, L. Y., Lin, S. Y., Lin, C. L. & Chang, T. A., Aug 14 2006, In : World Journal of Gastroenterology. 12, 30, p. 4897-4901 5 p.

Research output: Contribution to journalArticle

Chronic Hepatitis C
Fibrosis
Iron
Liver
Serum
8 Citations (Scopus)

Involvement of proapoptotic Bcl-2 family members in terbinafine-induced mitochondrial dysfunction and apoptosis in HL60 cells

Yang, K-C., Wu, C-C., Wu, C-H., Chen, J. H., Chu, C. H., Chen, C-H., Chou, Y. H., Wang, Y. J., Lee, W-S., Tseng, H., Lin, S-Y., Lee, C-H. & Ho, Y-S., Feb 2006, In : Food and Chemical Toxicology. 44, 2, p. 214-226 13 p.

Research output: Contribution to journalArticle

terbinafine
HL-60 Cells
apoptosis
Apoptosis
Mitochondria
30 Citations (Scopus)

Pro-oxidant and cytotoxic activities of atractylenolide I in human promyeloleukemic HL-60 cells

Wang, C. C., Lin, S. Y., Cheng, H. C. & Hou, W. C., Aug 2006, In : Food and Chemical Toxicology. 44, 8, p. 1308-1315 8 p.

Research output: Contribution to journalArticle

HL-60 Cells
oxidants
Reactive Oxygen Species
Cytotoxicity
superoxide dismutase
23 Citations (Scopus)

Stereoselective effects of 3-hydroxybutyrate on glucose utilization of rat cardiomyocytes

Tsai, Y. C., Chou, Y. C., Wu, A-B., Hu, C-M., Chen, C. Y., Chen, F. A. & Lee, J. A., Feb 16 2006, In : Life Sciences. 78, 12, p. 1385-1391 7 p.

Research output: Contribution to journalArticle

3-Hydroxybutyric Acid
Cardiac Myocytes
Rats
Glucose
Ketone Bodies
2007
46 Citations (Scopus)
Taiwanofungus camphoratus
antihypertensive effect
Inbred SHR Rats
Antihypertensive Agents
Methanol
23 Citations (Scopus)

Chitosan prevents the development of AOM-induced aberrant crypt foci in mice and suppressed the proliferation of AGS cells by inhibiting DNA synthesis

Lin, S. Y., Chan, H. Y., Shen, F. H., Chen, M. H., Wang, Y. J. & Yu, C. K., Apr 15 2007, In : Journal of Cellular Biochemistry. 100, 6, p. 1573-1580 8 p.

Research output: Contribution to journalArticle

Aberrant Crypt Foci
Chitosan
Cell Proliferation
Molecular Weight
Molecular weight
71 Citations (Scopus)

Comparative anti-inflammatory characterization of wild fruiting body, liquid-state fermentation, and solid-state culture of Taiwanofungus camphoratus in microglia and the mechanism of its action

Liu, D. Z., Liang, H. J., Chen, C. H., Su, C. H., Li, Z-H., Huang, C. T., Hou, W. C., Lin, S. Y., Zhong, W-B., Lin, P. J., Hung, L. F. & Liang, Y. C., Aug 15 2007, In : Journal of Ethnopharmacology. 113, 1, p. 45-53 9 p.

Research output: Contribution to journalArticle

Microglia
Fermentation
Methanol
Anti-Inflammatory Agents
Neurodegenerative Diseases
42 Citations (Scopus)
Patient Education
Blood Glucose
Fasting
Control Groups
Education
5 Citations (Scopus)
Taiwanofungus camphoratus
Amine Oxidase (Copper-Containing)
Scavenging
amines
biphenyl
22 Citations (Scopus)

NF-κB pathway is involved in griseofulvin-induced G2/M arrest and apoptosis in HL-60 cells

Uen, Y. H., Liu, D. Z., Weng, M. S., Ho, Y. S. & Lin, S. Y., Aug 1 2007, In : Journal of Cellular Biochemistry. 101, 5, p. 1165-1175 11 p.

Research output: Contribution to journalArticle

Griseofulvin
HL-60 Cells
Apoptosis
Tosylphenylalanyl Chloromethyl Ketone
G2 Phase Cell Cycle Checkpoints