Department of General Medicine

  • No. 250 Wu-Xing Street

    11031 Taipei

Research Output

2020
1 Citation (Scopus)
2019

Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5-diamino-6-chloro-N-(N-(2,6-dichlorobenzoyl)carbamimidoyl)pyrazine-2-carboxide

Lee, C. C., Chang, W. H., Chang, Y. S., Yang, J. M., Chang, C. S., Hsu, K. C., Chen, Y. T., Liu, T. Y., Chen, Y. C., Lin, S. Y., Wu, Y. C. & Chang, J. G., Jan 1 2019, In : Molecular Oncology. 13, 8, p. 1744-1762 19 p.

Research output: Contribution to journalArticle

Open Access
Open Access

Decellularized lymph node scaffolding as a carrier for dendritic cells to induce anti-tumor immunity

Lin, H. J., Wang, W., Huang, Y. Y., Liao, W. T., Lin, T. Y., Lin, S. Y. & Liu, D. Z., Nov 2019, In : Pharmaceutics. 11, 11, 553.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Deep Intronic Variant c.5999-277G>A of F8 Gene May Be a Hot-Spot Mutation for Mild Hemophilia A Patients Without Mutation in Exonic DNA

Chang, C-Y., Perng, C-L., Cheng, S-N., Hu, S-H., Wu, T-Y., Lin, S-Y. & Chen, Y-C., Jul 2019, In : European Journal of Haematology. 103, 1, p. 47-55 9 p.

Research output: Contribution to journalArticle

Open Access
7 Citations (Scopus)

Sodium hydrosulphide restores tumour necrosis factor-α-induced mitochondrial dysfunction and metabolic dysregulation in HL-1 cells

Lee, T. I., Kao, Y. H., Baigalmaa, L., Lee, T. W., Lu, Y. Y., Chen, Y. C., Chao, T. F. & Chen, Y. J., Jan 1 2019, (Accepted/In press) In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journalArticle

Open Access
2 Citations (Scopus)

Therapeutic potential of vitamin D in AGE/RAGE-related cardiovascular diseases

Lee, T. W., Kao, Y. H., Chen, Y. J., Chao, T. F. & Lee, T. I., Jan 1 2019, (Accepted/In press) In : Cellular and Molecular Life Sciences.

Research output: Contribution to journalReview article

4 Citations (Scopus)
2018
1 Citation (Scopus)

Activation of Class I histone deacetylases contributes to mitochondrial dysfunction in cardiomyocytes with altered complex activities

Lkhagva, B., Kao, Y. H., Lee, T. I., Lee, T. W., Cheng, W. L. & Chen, Y. J., May 1 2018, (Accepted/In press) In : Epigenetics. p. 1-10 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Aging modulates the substrate and triggers remodeling in atrial fibrillation

Lin, Y. K., Chen, Y. A., Lee, T. I., Chen, Y. C., Chen, S. A. & Chen, Y. J., Jan 1 2018, In : Circulation Journal. 82, 5, p. 1237-1244 8 p.

Research output: Contribution to journalReview article

8 Citations (Scopus)
8 Citations (Scopus)
1 Citation (Scopus)

Difference between observed and predicted glycated hemoglobin at baseline and treatment response to vildagliptin-based dual oral therapy in patients with type 2 diabetes

Wang, J. S., Hung, Y. J., Lu, Y. C., Tsai, C. L., Yang, W. S., Lee, T. I., Hsiao, Y. C. & Sheu, W. H. H., Apr 1 2018, In : Diabetes Research and Clinical Practice. 138, p. 119-127 9 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
3 Citations (Scopus)

MCPIP3 as a potential metastasis suppressor gene in human colorectal cancer

Suk, F. M., Chang, C. C., Lin, R. J., Lin, S. Y., Chen, Y. T. & Liang, Y. C., May 3 2018, In : International Journal of Molecular Sciences. 19, 5, 1350.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Oxidized phospholipids are proinflammatory and proatherogenic in hypercholesterolaemic mice

Que, X., Hung, M. Y., Yeang, C., Gonen, A., Prohaska, T. A., Sun, X., Diehl, C., Määttä, A., Gaddis, D. E., Bowden, K., Pattison, J., MacDonald, J. G., Ylä-Herttuala, S., Mellon, P. L., Hedrick, C. C., Ley, K., Miller, Y. I., Glass, C. K., Peterson, K. L., Binder, C. J. & 2 others, Tsimikas, S. & Witztum, J. L., Jun 14 2018, In : Nature. 558, 7709, p. 301-306 6 p.

Research output: Contribution to journalArticle

91 Citations (Scopus)

Surface assembly of poly(I:C) on polyethyleneimine-modified gelatin nanoparticles as immunostimulatory carriers for mucosal antigen delivery

Lin, S. F., Jiang, P. L., Tsai, J. S., Huang, Y. Y., Lin, S. Y., Lin, J. H. & Liu, D. Z., Jan 1 2018, (Accepted/In press) In : Journal of Biomedical Materials Research - Part B Applied Biomaterials.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Using modified information delivery to enhance the traditional pharmacy OSCE program at TMU – a pilot study

Lin, C. W., Chang, E. H., Clinciu, D. L., Peng, Y. T., Huang, W. C., Wu, C. C., Wu, J. C. & Li, Y. C., May 1 2018, In : Computer Methods and Programs in Biomedicine. 158, p. 147-152 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

ZFP36L1 and ZFP36L2 inhibit cell proliferation in a cyclin D-dependent and p53-independent manner

Suk, F-M., Chang, C-C., Lin, R-J., Lin, S-Y., Liu, S-C., Jau, C-F. & Liang, Y-C., Feb 9 2018, In : Scientific Reports. 8, 1, p. 2742

Research output: Contribution to journalArticle

14 Citations (Scopus)
2017

ADAM10 modulates calcitriol-regulated RAGE in cardiomyocytes

Lee, T. W., Kao, Y. H., Lee, T. I. & Chen, Y. J., Sep 1 2017, In : European Journal of Clinical Investigation. 47, 9, p. 675-683 9 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Discrepant effects of heart failure on electrophysiological property in right ventricular outflow tract and left ventricular outflow tract cardiomyocytes

Lu, Y. Y., Cheng, C. C., Tsai, C. F., Lin, Y. K., Lee, T. I., Chen, Y. C., Chen, S. A. & Chen, Y. J., Jun 1 2017, In : Clinical Science. 131, 12, p. 1317-1327 11 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Hot-Water Extracts from Roots of Vitis thunbergii var. taiwaniana and Identified ε-Viniferin Improve Obesity in High-Fat Diet-Induced Mice

Lu, Y. L., Lin, S. Y., Fang, S. U., Hsieh, Y. Y., Chen, C. R., Wen, C. L., Chang, C. I. & Hou, W. C., Mar 29 2017, In : Journal of Agricultural and Food Chemistry. 65, 12, p. 2521-2529 9 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Modulation the alternative splicing of GLA (IVS4+919G>A) in Fabry disease

Chang, W. H., Niu, D. M., Lu, C. Y., Lin, S. Y., Liu, T. C. & Chang, J. G., Apr 1 2017, In : PLoS One. 12, 4, e0175929.

Research output: Contribution to journalArticle

6 Citations (Scopus)

PPARs modulate cardiac metabolism and mitochondrial function in diabetes

Lee, T. W., Bai, K. J., Lee, T. I., Chao, T. F., Kao, Y. H. & Chen, Y. J., Jan 10 2017, In : Journal of Biomedical Science. 24, 1, 5.

Research output: Contribution to journalReview article

24 Citations (Scopus)

Primary Sjogren's syndrome and the risk of acute pancreatitis: A nationwide cohort study

Chang, C. C., Chang, Y. S., Wang, S. H., Lin, S. Y., Chen, Y. H. & Chen, J. H., Aug 1 2017, In : BMJ Open. 7, 8, e014807.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Rotura traqueal yatrogénica tras una intubación de urgencia

Translated title of the contribution: Iatrogenic Tracheal Rupture After Emergent IntubationChou, C. L., Lee, T. I. & Hu, T. Y., Feb 1 2017, In : Archivos de Bronconeumologia. 53, 2, p. 75-76 2 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)
2016

Does enhanced diabetes management reduce the risk and improve the outcome of tuberculosis?

Lo, H. Y., Yang, S. L., Lin, H. H., Bai, K. J., Lee, J. J., Lee, T. I. & Chiang, C. Y., Mar 1 2016, In : International Journal of Tuberculosis and Lung Disease. 20, 3, p. 376-382 7 p.

Research output: Contribution to journalArticle

14 Citations (Scopus)
10 Citations (Scopus)

Glucagon-like peptide-1 regulates calcium homeostasis and electrophysiological activities of HL-1 cardiomyocytes

Huang, J. H., Chen, Y. C., Lee, T. I., Kao, Y. H., Chazo, T. F., Chen, S. A. & Chen, Y. J., Apr 1 2016, In : Peptides. 78, p. 91-98 8 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

HDAC inhibition modulates cardiac PPARs and fatty acid metabolism in diabetic cardiomyopathy

Lee, T. I., Kao, Y. H., Tsai, W. C., Chung, C. C., Chen, Y. C. & Chen, Y. J., 2016, In : PPAR Research. 2016, 5938740.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Iatrogenic tracheal rupture after emergent intubation

Chou, C. L., Lee, T. I. & Hu, T. Y., 2016, (Accepted/In press) In : Archivos de Bronconeumologia.

Research output: Contribution to journalArticle

Successful multivessel percutaneous coronary intervention for acute coronary syndrome in a HIV-positive severe haemophiliac

Chang, C. Y., Lin, S. Y., Tsai, J. R., Tsai, C. H. & Chen, Y. C., Sep 1 2016, In : Haemophilia. 22, 5, p. e481-e484

Research output: Contribution to journalLetter

1 Citation (Scopus)
8 Citations (Scopus)

翻轉教學應用於擬真臨床技能學習之滿意度初探

Translated title of the contribution: An Exploratory Study on Simulated Clinical Skill Learning Satisfaction in the Flipped Approach康以諾, 林哲瑋(Che-Wei L, 陳建宇(Jonathan C-Y C, 曾德銘(Te-Ming T & 吳建志(Chien-Chih W, 2016, In : 台灣擬真醫學教育期刊. 3, 1, p. 23-31 9 p.

Research output: Contribution to journalArticle

2015

Bortezomib inhibits Burkitt's lymphoma cell proliferation by downregulating sumoylated hnRNP K and c-Myc expression

Suk, F. M., Lin, S. Y., Lin, R-J., Hsine, Y. H., Liao, Y. J., Fang, S. U. & Liang, Y. C., 2015, In : Oncotarget. 6, 28, p. 25988-26001 14 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)
13 Citations (Scopus)

CanMEDS角色與醫學生臨床情境認知之相容性探究

Translated title of the contribution: CanMEDS roles as framework for analyzing Taiwanese medical students’ reflective journals: an exploratory research for cross-cultural compatibility唐功培, 康以諾, 何建志, 曾櫻枝, 林宗達, 林時宜 & 陳建宇, 2015, In : 中榮醫教. 18, p. 21-28 8 p.

Research output: Contribution to journalArticle

Correction: Surface-enhanced Raman scattering on a silver film-modified Au nanoparticle-decorated SiO2 mask array

Chang, C. C., Chen, L. Y., Yang, K. H., Chen, Q. Y., Liang, Y. C., Lin, S. Y. & Liu, Y. C., Aug 12 2015, In : RSC Advances. 5, 86, p. 70501 1 p.

Research output: Contribution to journalArticle

Down-regulation of α-L-fucosidase 1 expression confers inferior survival for triple-negative breast cancer patients by modulating the glycosylation status of the tumor cell surface

Cheng, T. C., Tu, S. H., Chen, L. C., Chen, M. Y., Chen, W. Y., Lin, Y-K., Ho, C. T., Lin, S. Y., Wu, C. H. & Ho, Y. S., 2015, In : Oncotarget. 6, 25, p. 21283-21300 18 p.

Research output: Contribution to journalArticle

17 Citations (Scopus)
8 Citations (Scopus)

Effects of yam dioscorin interventions on improvements of the metabolic syndrome in high-fat diet-induced obese rats

Shih, S-L., Lin, Y-S., Lin, S-Y. & Hou, W-C., 2015, In : Botanical Studies. 56, 1, p. 1-9 9 p.

Research output: Contribution to journalArticle

10 Citations (Scopus)

Glycine hydroxamate inhibits tyrosinase activity and melanin contents through downregulating cAMP/PKA signaling pathways

Lin, Y. S., Wu, W. C., Lin, S. Y. & Hou, W. C., 2015, In : Amino Acids. 47, 3, p. 617-625 9 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

High anti-dengue virus activity of the OAS gene family is associated with increased severity of dengue

Simon-Loriere, E., Lin, R-J., Kalayanarooj, S. M., Chuansumrit, A., Casademont, I., Lin, S. Y., Yu, H. P., Lert-Itthiporn, W., Chaiyaratana, W., Tangthawornchaikul, N., Tangnararatchakit, K., Vasanawathana, S., Chang, B. L., Suriyaphol, P., Yoksan, S., Malasit, P., Despres, P., Paul, R., Lin, Y. L. & Sakuntabhai, A., 2015, In : Journal of Infectious Diseases. 212, 12, p. 2011-2020 10 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)
20 Citations (Scopus)

Increased risk of hepatocellular carcinoma in chronic hepatitis C patients with new onset diabetes: A nation-wide cohort study

Huang, Y. W., Wang, T. C., Yang, S. S., Lin, S. Y., Fu, S. C., Hu, J. T., Liu, C. J., Kao, J. H. & Chen, D. S., Oct 1 2015, In : Alimentary Pharmacology and Therapeutics. 42, 7, p. 902-911 10 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Japanese Encephalitis Virus Nonstructural Protein NS5 Interacts with Mitochondrial Trifunctional Protein and Impairs Fatty Acid β-Oxidation

Kao, Y. T., Chang, B. L., Liang, J. J., Tsai, H. J., Lee, Y. L., Lin, R. J. & Lin, Y. L., Mar 1 2015, In : PLoS Pathogens. 11, 3, p. 1-26 26 p., e1004750.

Research output: Contribution to journalArticle

12 Citations (Scopus)

Managing mass events and competitions with difficult-to-access locations using mobile electrocardiac monitoring

Shih, C-M., Lin, C-W., Clinciu, D. L., Jian, W-S., Kuo, T. B. J., Nguyen, P. A., Usman, I., Hsu, C. K., Owili, P. O. & Li, Y-C., Apr 13 2015, (Accepted/In press) In : Computer Methods and Programs in Biomedicine. 121, 2, p. 109-115

Research output: Contribution to journalArticle

5 Citations (Scopus)

N-hydroxycinnamide derivatives of osthole ameliorate hyperglycemia through activation of AMPK and p38 MAPK

Lee, W. H., Wu, H. H., Huang, W. J., Li, Y. N., Lin, R-J., Lin, S. Y. & Liang, Y. C., Mar 1 2015, In : Molecules. 20, 3, p. 4516-4529 14 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)