College of Medicine

Projects

Projects per year 2010 2022

• 2 Not started
• 305 Active
• 2581 Finished

Projects per year

Search results

• b - Ministry of Science and Technology

  Targeting Hepatitis C Virus-Induced Hepatocellular Carcinoma with Precision Medicine-Tailored Oncolytic Measles Virus(1/3)

  Lin, L. T.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Ultrasound-Guide Hypertonic Dextrose Injection for Chronic Subacromial Bursitis

  Huang, S.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• CAAT/enhancer binding protein beta訊息路徑參與thrombin誘導人類肺部上皮細胞IL-8/CXCL8表現之研究(3/3)

  Chen, B.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• Antibody Repertoire in Mycobacterium Tuberculosis Infection: Investigate Functional Immunoglobulins in Tb Infection and Translational Applications

  Tsai, I.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Systemic Safety Allograft Strategies for Cell Therapeutic Product Development: Targeting Unmet Medical Need Human Chronic Inflammatory Disease - Diabetes Mellitus /Decubitus Wound, Severe Burn, and Multiple Sclerosis( III )

  Huang, Y.

  5/1/19 → 4/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Research and Development Plans of Embodied Medical Humanity Education(The Practice)：Curriculum Design and Educational Action Research of the Medical Simulation Learning and the Clinical Practicum in Long-Term Respiratory Care

  Ho, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • curriculum 100%
  • simulation 72%
  • learning 62%
  • research and development 56%
  • expertise 45%

• Psychophysiological Effects of Lactobacillus Plantarum Ps128 in Patients with Major Depressive Disorder: a Pilot Study of 8-Week Open Trial

  Chen, C.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Lactobacillus plantarum 100%
  • Probiotics 77%
  • Gastrointestinal Microbiome 71%
  • Inflammation 53%
  • Permeability 46%

• Cell Penetrating Peptide Derived from Human Eosinophil Cationic Protein in Allergic Inflammation Modulation- Enhancing Delivery and Effect of Anti-Sense Rna Targeting Stat-6

  Hou, T. & Lee, Y.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Role of Er Stress in Evodiamine-Induced Apoptosis and G2/M Arrest of Human Colorectal Carcinoma Cells

  Chen, Y.

  8/1/12 → 7/31/13

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Colorectal Neoplasms 100%
  • Apoptosis 41%
  • Cyclin B1 30%
  • Proteins 16%
  • Structure-Activity Relationship 13%

• The Study of Therapeutic Effects for Stroke with Phenserine, an Amyloid Precursor Protein Inhibitor, in Rodent Focal Cerebral Ischemia Model

  Chang, C. & Chiang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • phenserine 100%
  • Stroke 75%
  • Amyloid beta-Protein Precursor 49%
  • pifithrin 40%
  • Stem Cells 31%

• 乳癌是目前世界上女性癌症病患中為數最多的癌症之ㄧ。腺病毒蛋白type 5 E1A (E1A)和許多抗腫瘤作用有關，曾於多種癌症如乳癌、卵巢癌及頭頸癌之病患進行臨床基因治療試驗。許多的研究指出E1A具有多項抗腫瘤的功能，包括抑制腫瘤的發生、增加腫瘤細胞對於化療藥物的感受性以及減少腫瘤轉移的現象。腫瘤的轉移對於癌症患者的死亡率有極大的影響當然也包括了乳癌的患者。E1A於抑制腫瘤發展的過程中具有多重生物學上的意義，這也促使我們想要釐清E1A抑制癌症的機制。因此，我們對於了解E1A抑制癌症轉移相關的分子機制感到有興趣，並期望藉以作為未來改進乳癌病人臨床試驗的基石。我們初步的實驗結果顯示，E1A可以有效的抑制Glucose-regulated protein 78 (GRP78)這種已被廣泛報導和腫瘤惡化及轉移相關的蛋白的表現。 提出此研究計劃之目的在於詳細探討E1A所造成的抑制癌轉移作用中，GRP78所扮演的生物功能及其調控的機轉。為了達到此目的，我們將著重於E1A如何調控GRP78表現並進而展現對乳癌轉移的抑制作用。以下為此項研究計畫的四大主要目標： 目標一：探討GRP78在E1A所抑制之癌細胞移行及侵入作用中所扮演的角色 目標二：研究E1A抑制GRP78表現之分子機轉 目標三：於動物模式中驗證GRP78的表現對於E1A抗腫瘤作用的影響 目標四：探討GRP78及其相關分子的表現在乳癌病人的臨床重要性 完成以上的主要目標能夠幫助我們對於E1A之抗腫瘤轉移作用建立更加詳細的分子訊息傳遞機制。另外，藉由此研究計畫的新發現也許可以對未來發展癌症治療上提供更多具有潛力的標的物。

  Wang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • glucose-regulated proteins 100%
  • Neoplasm Metastasis 25%
  • Neoplasms 23%
  • Breast Neoplasms 16%
  • Psychological Inhibition 12%

• The Neuroprotection Effect and Mechanism of Long Non-Coding RNA MALAT1 in Acute Ischemic Stroke

  Chi, N. & Hu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Stroke 100%
  • Long Noncoding RNA 67%
  • Ischemia 47%
  • Untranslated RNA 47%
  • Cell Line 24%

• Roles of Central OX2R Activities in the Pathophysiology of Hypertension in SHR

  Hwang, L.

  8/1/13 → 7/31/14

  Project: A - Government Institution › b - Ministry of Science and Technology

• To Investigate the Role of Rbm3 in Therapeutic Hypothermia Mediated Neuroprotection in Ischemia Stroke(2/3)

  Yang, C. H.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Dissected the Role of Defensin 6 (Def 6),The Clinically Therapeutic Implication and Drug Development in Colon Cancer

  Wei, P.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • colorectal neoplasms 100%
  • neoplasms 37%
  • therapeutics 31%
  • metastasis 31%
  • death 25%

• Investigation on Developing Novel Biomarkers and Treatments in the Patients with Fibromyalgia

  Kang, J.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Transcranial Direct Current Stimulation 38%
  • Exercise 32%
  • Virtual Reality 30%
  • Biomarkers 12%

• Anti-Tumor Mechanisms of the Novel Series of Aliphatic Hydroxamate Derivatives, Wmj-J Compounds

  Hsu, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • WMJ-S-001 100%
  • Neoplasms 73%
  • Colorectal Neoplasms 66%
  • Acetylation 65%
  • HCT116 Cells 53%

• Bsp-Like Repeat Family Proteins in Bacterial Immune Evasion and Biofilm Formation in Viridans Streptococci-Induced Infective Endocarditis

  Jung, C.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• Developing Smart Voice-Control Interfaces and Establishing Smart Living and Work Environments: Based on the Unmet Needs of the Spinal Quadriplegics(Focusing Topic: A6)( II )

  Chen, S.

  1/1/18 → 12/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Platelet Nano-Scale Vesicles: Delivery Cargo Platform of Neuroregenerative Biomolecules to the Brain(I)

  Burnouf, T. P. R.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Using Automatic Facial Expression Analysis as a Tool to Long Term Evaluation in Fibromyalgia Patients

  Kang, J., Lee, H. & Yeh, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fibromyalgia 100%
  • Systems Analysis 42%
  • Cell Phone 34%
  • Facial Expression 33%
  • Clinical Psychology 12%

• Functional Role of Transcription Factor Sp1 in Brain Neuronal Injury (III)

  Chang, W.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

• Therapeutic Effects of New Derivatives of Thalidomide and p53 Inhibitors in Acute Traumatic Injury---Dosing Regimen, Routes and Multiple Mechanism

  Wang, J.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Research Personnel 62%
  • pifithrin 60%
  • Thalidomide 47%
  • Therapeutic Uses 41%

• Jet Lag as a Potent Manipulator of Mood(1/2)

  Myung, J.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Effects of Different Sources of n-3 Fatty Acids on Bone Loss, Body Fat and Inflammatory Markers in Osteoporotic Condition with Diabetes

  Chiu, W. & Fong, T.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Fatty Acid 100%
  • Fat 66%
  • Ligand 24%
  • Deoxypyridinoline 20%
  • Marker 19%

• Investigating the Role of Ck1 Delta in Tumor Progression, and as a Therapeutic Target for New Drug Discovery in Bladder Cancer.

  Chen, C.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Marker 100%
  • Threonine 63%
  • Serine 53%
  • Pharmacokinetics 43%
  • Flow 36%

• Repositioning Drug Therapies for Traumatic Brain Injury

  Chiu, W., Chang, C. & Chiang, Y.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Wounds and Injuries 37%
  • Dipeptidyl-Peptidase IV Inhibitors 33%
  • Incretins 33%
  • Acetylcysteine 28%

• Development of Cortical Electrical Stimulation Technique for Improving Neuroplasticity and Motor Function in Parkinsonian Rats

  Hsieh, T., Chiang, Y. & Peng, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• 結合奈米診斷治療、影像免疫基因圖譜與人工智慧於原發性與再復發膠質母細胞瘤之研究-建立原發性和再復發膠質母細胞瘤免疫圖譜以及建立免疫療法(2/3)

  Lee, G.

  8/1/20 → 7/31/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• 建置公衛研究專用之衛星遙測影像環境資料自動化平台

  Chuang, T.

  8/1/20 → 7/1/21

  Project: A - Government Institution › b - Ministry of Science and Technology

• Study the Function and Regulation of Mirnas in Pancreatic Cancer Progression( III )

  Huang, M.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Implication of Plasminogen Activator Inhibitor-1 in the Regulation of Thrombin-Induced Fibrogenesis in Inflammatory Pleural Effusions.

  Chung, C.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Plasminogen Activator Inhibitor 1 100%
  • Thrombin 88%
  • Fibrosis 40%
  • Collagen 18%
  • Pleural Effusion 17%

• Studies of Folic Acid-Induced Anti-Tumor Growth Activity---Anti-Angiogensis and Anti-Cancer Cell Growth

  Lee, W.

  8/1/10 → 7/31/11

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Folic Acid 100%
  • Antiangiogenic 47%
  • Gonadal Steroid Hormone 12%
  • Antisense Oligonucleotide 11%
  • Protein 10%

• Development of Efficient Immunoglobulin G Analytical Method for Investigating Autoantibody Biomarkers for Pancreatic Disease (Continuous Research)

  Tsai, I.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • autoantibodies 100%
  • biomarkers 65%
  • pancreatic diseases 64%
  • pancreatic neoplasms 58%
  • pancreatitis 53%

• Effect of Metabolic Abnormality on Dna Methylation in Schizophrenia: the Role of One-Carbon Metabolism

  Lu, M.

  8/1/19 → 7/31/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• 評估 SSRI 抗憂鬱藥物 sertraline 及 paroxetine 對正常與阿茲海默症高危險群老年人的影響

  Shen, S.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Role and Molecular Mechanism of PPARα in Acute Kidney Injury---Focus on the Protective Effect in Renal Tubular Cell

  Hsu, Y., Chen, T. & Chen, C.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Type C Phospholipases 73%
  • Kidney 56%
  • Acute Kidney Injury 37%
  • Gentamicins 27%

• New drug development using dengue virus-infected mouse models(I)

  Lin, C.

  1/1/16 → 12/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

• Hbx and Its Associated Epigenetic Regulators in Promoting Senp1 Expression and Cancer Stemness in Hbv-Related Hepatocellular Carcinoma: the Role of Hbx/Senp1 and Its Clinical Impact

  Wu, Y.

  8/1/18 → 7/31/19

  Project: A - Government Institution › b - Ministry of Science and Technology

• Development of Vector-Borne Disease Automated Early Warning System--Toward Malaria Eradication in Swaziland

  Chuang, T.

  8/1/18 → 7/1/19

  Project: A - Government Institution › b - Ministry of Science and Technology

  • malaria 100%
  • early warning system 35%
  • population movement 14%
  • program 10%
  • public health 8%

• 溶瘤麻疹病毒抗乳腺癌治療之開發研究(3/3)

  Lin, L. T.

  8/1/16 → 7/31/17

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Measles virus 100%
  • Breast Neoplasms 40%
  • Adenocarcinoma 22%
  • Reverse Genetics 18%
  • Neoplasms 11%

• Genomic, Epigenomic and Epiproteomic Analysis of Etk/Bmx Traumatic Brain Injury

  Chen, K., Chiang, Y. & Wu, C.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Traumatic Brain Injury 100%
  • Protein Kinases 15%
  • Epigenomics 14%
  • Tec protein-tyrosine kinase 14%
  • Inflammation Mediators 10%

• 內毒素引發肺迷走感覺神經過度敏感 ：Sigma-1受器的角色

  Hsu, C.

  7/1/19 → 2/1/20

  Project: A - Government Institution › b - Ministry of Science and Technology

• The Impact of Environmental Change on Spatial and Temporal Variations of Dengue Outbreaks---Toward Dengue Early Warning System

  Chuang, T.

  8/1/15 → 7/31/16

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Land use 100%
  • Population dynamics 81%
  • Alarm systems 62%
  • Remote sensing 57%
  • Satellites 42%

• The Impact of Environmental Change on Spatial and Temporal Variations of Dengue Outbreaks-- Part Ii

  Chuang, T.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • mosquito 100%
  • land cover 91%
  • dengue fever 83%
  • climate 60%
  • environmental factor 46%

• Dissected the Role of Glucosed-Regulated Portein 78 in the Progression, Metastasis and Therapy of Colorectal Cancer

  Wei, P.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • colorectal neoplasms 100%
  • metastasis 69%
  • neoplasms 55%
  • endoplasmic reticulum 32%
  • death 27%

• The Carotid Atherosclerosis and Cardiac Function Measured by Ultrasonography in Bipolar Mania and Their Relevent Clinical Factors

  Tsai, S.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

• Prevention and Treatment of Aki-Ckd Continuum: Targeting on Pparα-Mediated Mitochodria Protection

  Hsu, Y.

  8/1/17 → 7/31/18

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Acute Kidney Injury 100%
  • Chronic Renal Insufficiency 76%
  • PPAR alpha 42%
  • beraprost 27%
  • coenzyme Q10 21%

• The Role of CD24 in TNF-Alpha-Inhibited Erythroid Differentiation

  Huang, H.

  8/1/14 → 7/31/15

  Project: A - Government Institution › b - Ministry of Science and Technology

  • Tumor Necrosis Factor-alpha 100%
  • Hematopoietic Stem Cells 92%
  • Erythropoietin 49%
  • Anemia 39%
  • Inflammation 34%

• The Roles of Micrornas in Endothelin-1 and Hypoxia-Induced Ctgf Production

  Chen, Y.

  8/1/11 → 7/31/12

  Project: A - Government Institution › b - Ministry of Science and Technology

  • MicroRNAs 100%
  • Endothelin-1 59%
  • Hypoxia 31%
  • Fibrosis 29%
  • Lung 23%